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Volumn 3, Issue 1, 2014, Pages 81-90

Concise review: Microfluidic technology platforms: Poised to accelerate development and translation of stem cell-derived therapies

Author keywords

Investigative techniques; Microfluidics; Stem cell research; Stem cells; Translational medical research

Indexed keywords

6 BROMOINDIRUBIN 30 OXIME; CHIR 99021; GLYCOGEN SYNTHASE KINASE 3 INHIBITOR; N (2, 3 DIHYDROXYPROPOXY) 3, 4 DIFLUORO 2 (2 FLUORO 4 IODOANILINO) BENZAMIDE; UNCLASSIFIED DRUG;

EID: 84892718887     PISSN: 21576564     EISSN: 21576580     Source Type: Journal    
DOI: 10.5966/sctm.2013-0118     Document Type: Article
Times cited : (23)

References (70)
  • 1
    • 0032491416 scopus 로고    scopus 로고
    • Embryonic stem cell lines derived from human blastocysts
    • Thomson JA, Itskovitz-Eldor J, Shapiro SS et al. Embryonic stem cell lines derived from human blastocysts. Science 1998;282:1145-1147.
    • (1998) Science , vol.282 , pp. 1145-1147
    • Thomson, J.A.1    Itskovitz-Eldor, J.2    Shapiro, S.S.3
  • 2
    • 36248966518 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult human fibroblasts by defined factors
    • Takahashi K, Tanabe K, OhnukiMet al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007; 131:861-872.
    • (2007) Cell , vol.131 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3
  • 3
    • 0034614576 scopus 로고    scopus 로고
    • Stem cells: Units of development, units of regeneration, and units in evolution
    • Weissman IL. Stem cells: Units of development, units of regeneration, and units in evolution. Cell 2000;100:157-168.
    • (2000) Cell , vol.100 , pp. 157-168
    • Weissman, I.L.1
  • 4
    • 0033515827 scopus 로고    scopus 로고
    • Multilineage potential of adult human mesenchymal stem cells
    • PittengerMF, Mackay AM, Beck SC et al. Multilineage potential of adult human mesenchymal stem cells. Science 1999;284:143-147.
    • (1999) Science , vol.284 , pp. 143-147
    • Pittenger, M.F.1    McKay, A.M.2    Beck, S.C.3
  • 5
    • 84861345298 scopus 로고    scopus 로고
    • Process engineering of human pluripotent stem cells for clinical application
    • Serra M, Brito C, Correia C et al. Process engineering of human pluripotent stem cells for clinical application. Trends Biotechnol 2012; 30:350-359.
    • (2012) Trends Biotechnol , vol.30 , pp. 350-359
    • Serra, M.1    Brito, C.2    Correia, C.3
  • 6
    • 0032403465 scopus 로고    scopus 로고
    • Rapid prototyping of microfluidic systems in poly(dimethylsiloxane)
    • Duffy DC, McDonald JC, Schueller OJ et al. Rapid prototyping of microfluidic systems in poly(dimethylsiloxane). Anal Chem 1998;70: 4974-4984.
    • (1998) Anal Chem , vol.70 , pp. 4974-4984
    • Duffy, D.C.1    McDonald, J.C.2    Schueller, O.J.3
  • 7
    • 84873417297 scopus 로고    scopus 로고
    • Arrayed cellular environments for stem cells and regenerative medicine
    • Titmarsh DM, Chen H, Wolvetang EJ et al. Arrayed cellular environments for stem cells and regenerative medicine. Biotechnol J 2013; 8:167-179.
    • (2013) Biotechnol J , vol.8 , pp. 167-179
    • Titmarsh, D.M.1    Chen, H.2    Wolvetang, E.J.3
  • 8
    • 77953571969 scopus 로고    scopus 로고
    • Latest developments in microfluidic cell biology and analysis systems
    • Salieb-Beugelaar GB, Simone G, Arora A et al. Latest developments in microfluidic cell biology and analysis systems. Anal Chem 2010;82:4848-4864.
    • (2010) Anal Chem , vol.82 , pp. 4848-4864
    • Salieb-Beugelaar, G.B.1    Simone, G.2    Arora, A.3
  • 9
    • 77953353983 scopus 로고    scopus 로고
    • Regulating microenvironmental stimuli for stem cells and cancer cells using microsystems
    • Park JY, Takayama S, Lee S-H. Regulating microenvironmental stimuli for stem cells and cancer cells using microsystems. Integr Biol (Camb) 2010;2:229-240.
    • (2010) Integr Biol (Camb) , vol.2 , pp. 229-240
    • Park, J.Y.1    Takayama, S.2    Lee, S.-H.3
  • 10
    • 84864539307 scopus 로고    scopus 로고
    • Revisiting lab-on-a-chip technology for drug discovery
    • Neuzi P, Giselbrecht S, Länge K et al. Revisiting lab-on-a-chip technology for drug discovery. Nat Rev Drug Discov 2012;11:620-632.
    • (2012) Nat Rev Drug Discov , vol.11 , pp. 620-632
    • Neuzi, P.1    Giselbrecht, S.2    Länge, K.3
  • 11
    • 84873437242 scopus 로고    scopus 로고
    • Microfluidic systems: A new toolbox for pluripotent stem cells
    • Lesher-Perez SC, Frampton JP, Takayama S. Microfluidic systems: A new toolbox for pluripotent stem cells. Biotechnol J 2013;8: 180-191.
    • (2013) Biotechnol J , vol.8 , pp. 180-191
    • Lesher-Perez, S.C.1    Frampton, J.P.2    Takayama, S.3
  • 12
    • 77956061536 scopus 로고    scopus 로고
    • Label-free cell separation and sorting in microfluidic systems
    • Gossett DR, Weaver WM, Mach AJ et al. Label-free cell separation and sorting in microfluidic systems. Anal Bioanal Chem 2010;397: 3249-3267.
    • (2010) Anal Bioanal Chem , vol.397 , pp. 3249-3267
    • Gossett, D.R.1    Weaver, W.M.2    Mach, A.J.3
  • 13
    • 84862224301 scopus 로고    scopus 로고
    • Cell separation based on size and deformability using microfluidic funnel ratchets
    • McFaul SM, Lin BK, Ma H. Cell separation based on size and deformability using microfluidic funnel ratchets. Lab Chip 2012;12: 2369-2376.
    • (2012) Lab Chip , vol.12 , pp. 2369-2376
    • McFaul, S.M.1    Lin, B.K.2    Ma, H.3
  • 14
    • 78049244939 scopus 로고    scopus 로고
    • Adhesion based detection, sorting and enrichment of cells in microfluidic Lab-on-Chip devices
    • Didar TF, Tabrizian M. Adhesion based detection, sorting and enrichment of cells in microfluidic Lab-on-Chip devices. Lab Chip 2010;10:3043-3053.
    • (2010) Lab Chip , vol.10 , pp. 3043-3053
    • Didar, T.F.1    Tabrizian, M.2
  • 15
    • 84877574846 scopus 로고    scopus 로고
    • Adhesion strength-based, label-free isolation of human pluripotent stem cells
    • Singh A, Suri S, Lee T et al. Adhesion strength-based, label-free isolation of human pluripotent stem cells. Nat Methods 2013;10: 438-444.
    • (2013) Nat Methods , vol.10 , pp. 438-444
    • Singh, A.1    Suri, S.2    Lee, T.3
  • 16
    • 84858984802 scopus 로고    scopus 로고
    • Cell sorting by deterministic cell rolling
    • Choi S, Karp JM, Karnik R. Cell sorting by deterministic cell rolling. Lab Chip 2012;12: 1427-1430.
    • (2012) Lab Chip , vol.12 , pp. 1427-1430
    • Choi, S.1    Karp, J.M.2    Karnik, R.3
  • 17
    • 77953762828 scopus 로고    scopus 로고
    • Continuous sorting of heterogeneous-sized embryoid bodies
    • Lillehoj PB, Tsutsui H, Valamehr B et al. Continuous sorting of heterogeneous-sized embryoid bodies. Lab Chip 2010;10:1678-1682.
    • (2010) Lab Chip , vol.10 , pp. 1678-1682
    • Lillehoj, P.B.1    Tsutsui, H.2    Valamehr, B.3
  • 18
    • 79551565557 scopus 로고    scopus 로고
    • Agitation can induce differentiation of human pluripotent stem cells in microcarrier cultures
    • Leung HW, Chen A, Choo AB et al. Agitation can induce differentiation of human pluripotent stem cells in microcarrier cultures. Tissue Eng Part C Methods 2011;17:165-172.
    • (2011) Tissue Eng Part C Methods , vol.17 , pp. 165-172
    • Leung, H.W.1    Chen, A.2    Choo, A.B.3
  • 19
    • 79954601102 scopus 로고    scopus 로고
    • Fluid shear stress primes mouse embryonic stem cells for differentiation in a self-renewing environment via heparan sulfate proteoglycans transduction
    • Toh Y-C, Voldman J. Fluid shear stress primes mouse embryonic stem cells for differentiation in a self-renewing environment via heparan sulfate proteoglycans transduction. FASEB J 2011;25:1208-1217.
    • (2011) FASEB J , vol.25 , pp. 1208-1217
    • Toh, Y.-C.1    Voldman, J.2
  • 20
    • 33644648070 scopus 로고    scopus 로고
    • Microfluidic arrays for logarithmically perfused embryonic stem cell culture
    • KimL, Vahey MD, Lee HY et al. Microfluidic arrays for logarithmically perfused embryonic stem cell culture. Lab Chip 2006;6:394-406.
    • (2006) Lab Chip , vol.6 , pp. 394-406
    • Kim, L.1    Vahey, M.D.2    Lee, H.Y.3
  • 21
    • 80054017005 scopus 로고    scopus 로고
    • Optimization of flowrate for expansion of human embryonic stem cells in perfusion microbioreactors
    • Titmarsh D, Hidalgo A, Turner J et al. Optimization of flowrate for expansion of human embryonic stem cells in perfusion microbioreactors. Biotechnol Bioeng 2011; 108:2894-2904.
    • (2011) Biotechnol Bioeng , vol.108 , pp. 2894-2904
    • Titmarsh, D.1    Hidalgo, A.2    Turner, J.3
  • 22
    • 78149265781 scopus 로고    scopus 로고
    • Fluid shear stress promotes an endothelial-like phenotype during the early differentiation of embryonic stemcells
    • Ahsan T, NeremRM. Fluid shear stress promotes an endothelial-like phenotype during the early differentiation of embryonic stemcells. Tissue Eng Part A 2010;16:3547-3553.
    • (2010) Tissue Eng Part A , vol.16 , pp. 3547-3553
    • Ahsan, T.1    Nerem, R.M.2
  • 23
    • 84876308427 scopus 로고    scopus 로고
    • Regulation of fibrochondrogenesis of mesenchymal stem cells in an integrated microfluidic platform embedded with biomimetic nanofibrous scaffolds
    • Zhong W, Zhang W, Wang S et al. Regulation of fibrochondrogenesis of mesenchymal stem cells in an integrated microfluidic platform embedded with biomimetic nanofibrous scaffolds. PLoS One 2013;8:e61283.
    • (2013) PLoS One , vol.8
    • Zhong, W.1    Zhang, W.2    Wang, S.3
  • 24
    • 77953365784 scopus 로고    scopus 로고
    • Extrinsic regulation of pluripotent stem cells
    • Pera MF, Tam PPL. Extrinsic regulation of pluripotent stem cells. Nature 2010;465:713-720.
    • (2010) Nature , vol.465 , pp. 713-720
    • Pera, M.F.1    Tam, P.P.L.2
  • 25
    • 59649114748 scopus 로고    scopus 로고
    • An integrated microfluidic culture device for quantitative analysis of human embryonic stem cells
    • Kamei K-i, Guo S, Yu ZT et al. An integrated microfluidic culture device for quantitative analysis of human embryonic stem cells. Lab Chip 2009;9:555-563.
    • (2009) Lab Chip , vol.9 , pp. 555-563
    • Kamei, K.-I.1    Guo, S.2    Yu, Z.T.3
  • 26
    • 67649396057 scopus 로고    scopus 로고
    • Microfluidic culture of single human embryonic stem cell colonies
    • Villa-Diaz LG, Torisawa YS, Uchida T et al. Microfluidic culture of single human embryonic stem cell colonies. Lab Chip 2009;9:1749-1755.
    • (2009) Lab Chip , vol.9 , pp. 1749-1755
    • Villa-Diaz, L.G.1    Torisawa, Y.S.2    Uchida, T.3
  • 27
    • 84879756725 scopus 로고    scopus 로고
    • Full factorial screening of human embryonic stem cell maintenance with multiplexed microbioreactor arrays
    • Titmarsh DM, Ovchinnikov DA, Wolvetang EJ et al. Full factorial screening of human embryonic stem cell maintenance with multiplexed microbioreactor arrays. Biotechnol J 2013;8:822-834.
    • (2013) Biotechnol J , vol.8 , pp. 822-834
    • Titmarsh, D.M.1    Ovchinnikov, D.A.2    Wolvetang, E.J.3
  • 28
    • 77950788166 scopus 로고    scopus 로고
    • Microfluidic image cytometry for quantitative single-cell profiling of human pluripotent stem cells in chemically defined conditions
    • Kamei K-i, Ohashi M, Gschweng E et al. Microfluidic image cytometry for quantitative single-cell profiling of human pluripotent stem cells in chemically defined conditions. Lab Chip 2010;10:1113-1119.
    • (2010) Lab Chip , vol.10 , pp. 1113-1119
    • Kamei, K.-I.1    Ohashi, M.2    Gschweng, E.3
  • 29
    • 39349106325 scopus 로고    scopus 로고
    • Differentiation of embryonic stem cells to clinically relevant populations: Lessons from embryonic development
    • Murry CE, Keller G. Differentiation of embryonic stem cells to clinically relevant populations: Lessons from embryonic development. Cell 2008;132:661-680.
    • (2008) Cell , vol.132 , pp. 661-680
    • Murry, C.E.1    Keller, G.2
  • 30
    • 34247226529 scopus 로고    scopus 로고
    • Gene function in mouse embryogenesis: Get set for gastrulation
    • Tam PPL, Loebel DAF. Gene function in mouse embryogenesis: Get set for gastrulation. Nat Rev Genet 2007;8:368-381.
    • (2007) Nat Rev Genet , vol.8 , pp. 368-381
    • Tam, P.P.L.1    Loebel, D.A.F.2
  • 31
    • 84862526635 scopus 로고    scopus 로고
    • Selfformation of optic cups and storable stratified neural retina from human ESCs
    • Nakano T, Ando S, Takata N et al. Selfformation of optic cups and storable stratified neural retina from human ESCs. Cell Stem Cell 2012;10:771-785.
    • (2012) Cell Stem Cell , vol.10 , pp. 771-785
    • Nakano, T.1    Ando, S.2    Takata, N.3
  • 32
    • 58049213491 scopus 로고    scopus 로고
    • Micro-bioreactor arrays for controlling cellular environments: Design principles for human embryonic stem cell applications
    • Cimetta E, Figallo E, Cannizzaro C et al. Micro-bioreactor arrays for controlling cellular environments: Design principles for human embryonic stem cell applications. Methods 2009; 47:81-89.
    • (2009) Methods , vol.47 , pp. 81-89
    • Cimetta, E.1    Figallo, E.2    Cannizzaro, C.3
  • 33
    • 34249821066 scopus 로고    scopus 로고
    • Micro-bioreactor array for controlling cellular microenvironments
    • Figallo E, Cannizzaro C, Gerecht S et al. Micro-bioreactor array for controlling cellular microenvironments. Lab Chip 2007;7:710-719.
    • (2007) Lab Chip , vol.7 , pp. 710-719
    • Figallo, E.1    Cannizzaro, C.2    Gerecht, S.3
  • 34
    • 17144398875 scopus 로고    scopus 로고
    • Human neural stem cell growth and differentiation in a gradient-generating microfluidic device
    • Chung BG, Flanagan LA, Rhee SW et al. Human neural stem cell growth and differentiation in a gradient-generating microfluidic device. Lab Chip 2005;5:401-406.
    • (2005) Lab Chip , vol.5 , pp. 401-406
    • Chung, B.G.1    Flanagan, L.A.2    Rhee, S.W.3
  • 35
    • 72849143548 scopus 로고    scopus 로고
    • Differentiation of neural progenitor cells in a microfluidic chip-generated cytokine gradient
    • Park JY, Kim SK, Woo DH et al. Differentiation of neural progenitor cells in a microfluidic chip-generated cytokine gradient. STEM CELLS 2009;27:2646-2654.
    • (2009) STEM CELLS , vol.27 , pp. 2646-2654
    • Park, J.Y.1    Kim, S.K.2    Woo, D.H.3
  • 36
    • 84867322318 scopus 로고    scopus 로고
    • Spatiotemporally controlled delivery of soluble factors for stem cell differentiation
    • Kawada J, Kimura H, Akutsu H et al. Spatiotemporally controlled delivery of soluble factors for stem cell differentiation. Lab Chip 2012; 12:4508-4515.
    • (2012) Lab Chip , vol.12 , pp. 4508-4515
    • Kawada, J.1    Kimura, H.2    Akutsu, H.3
  • 37
    • 84872090939 scopus 로고    scopus 로고
    • Microfluidic bioreactor for dynamic regulation of early mesodermal commitment in human pluripotent stem cells
    • Cimetta E, Sirabella D, Yeager K et al. Microfluidic bioreactor for dynamic regulation of early mesodermal commitment in human pluripotent stem cells. Lab Chip 2013;13:355-364.
    • (2013) Lab Chip , vol.13 , pp. 355-364
    • Cimetta, E.1    Sirabella, D.2    Yeager, K.3
  • 38
    • 84884412620 scopus 로고    scopus 로고
    • Patterning pluripotency in embryonic stem cells
    • Zhang YS, Sevilla A, WanLQ et al. Patterning pluripotency in embryonic stem cells. STEM CELLS 2013;31:1806-1815.
    • (2013) STEM CELLS , vol.31 , pp. 1806-1815
    • Zhang, Y.S.1    Sevilla, A.2    Wan, L.Q.3
  • 39
    • 84871593878 scopus 로고    scopus 로고
    • Microbioreactor arrays for full factorial screening of exogenous and paracrine factors in human embryonic stem cell differentiation
    • Titmarsh DM, Hudson JE, Hidalgo A et al. Microbioreactor arrays for full factorial screening of exogenous and paracrine factors in human embryonic stem cell differentiation. PLoS One 2012;7:e52405.
    • (2012) PLoS One , vol.7
    • Titmarsh, D.M.1    Hudson, J.E.2    Hidalgo, A.3
  • 40
    • 37349067768 scopus 로고    scopus 로고
    • Microfluidic flow-encoded switching for parallel control of dynamic cellular microenvironments
    • King KR, Wang S, Jayaraman A et al. Microfluidic flow-encoded switching for parallel control of dynamic cellular microenvironments. Lab Chip 2008;8:107-116.
    • (2008) Lab Chip , vol.8 , pp. 107-116
    • King, K.R.1    Wang, S.2    Jayaraman, A.3
  • 41
    • 36448935709 scopus 로고    scopus 로고
    • Versatile, fully automated, microfluidic cell culture system
    • G'Omez-Sjöberg R, Leyrat AA, Pirone DM et al. Versatile, fully automated, microfluidic cell culture system. Anal Chem 2007; 79:8557-8563.
    • (2007) Anal Chem , vol.79 , pp. 8557-8563
    • G'Omez-Sjöberg, R.1    Leyrat, A.A.2    Pirone, D.M.3
  • 42
    • 79959830458 scopus 로고    scopus 로고
    • High-throughput analysis of single hematopoietic stem cell proliferation in microfluidic cell culture arrays
    • Lecault V, VaninsbergheM, Sekulovic S et al. High-throughput analysis of single hematopoietic stem cell proliferation in microfluidic cell culture arrays. Nat Methods 2011; 8:581-586.
    • (2011) Nat Methods , vol.8 , pp. 581-586
    • Lecault, V.1    Vaninsberghe, M.2    Sekulovic, S.3
  • 43
    • 84863315972 scopus 로고    scopus 로고
    • Probing embryonic stem cell autocrine and paracrine signaling using microfluidics
    • Przybyla L, Voldman J. Probing embryonic stem cell autocrine and paracrine signaling using microfluidics. Annu Rev Anal Chem (Palo Alto Calif) 2012;5:293-315.
    • (2012) Annu Rev Anal Chem (Palo Alto Calif) , vol.5 , pp. 293-315
    • Przybyla, L.1    Voldman, J.2
  • 44
    • 68949135330 scopus 로고    scopus 로고
    • Computational model and microfluidic platform for the investigation of paracrine and autocrine signaling in mouse embryonic stem cells
    • Ellison D, Munden A, Levchenko A. Computational model and microfluidic platform for the investigation of paracrine and autocrine signaling in mouse embryonic stem cells. Mol Biosyst 2009;5:1004-1012.
    • (2009) Mol Biosyst , vol.5 , pp. 1004-1012
    • Ellison, D.1    Munden, A.2    Levchenko, A.3
  • 45
    • 84857735045 scopus 로고    scopus 로고
    • Predictive microfluidic control of regulatory ligand trajectories in individual pluripotent cells
    • Moledina F, Clarke G, Oskooei A et al. Predictive microfluidic control of regulatory ligand trajectories in individual pluripotent cells. Proc Natl Acad Sci USA 2012;109: 3264-3269.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 3264-3269
    • Moledina, F.1    Clarke, G.2    Oskooei, A.3
  • 46
    • 79961146650 scopus 로고    scopus 로고
    • Microfluidic perfusion for regulating diffusible signaling in stem cells
    • Blagovic K, Kim LY, Voldman J. Microfluidic perfusion for regulating diffusible signaling in stem cells. PLoS One 2011;6:e22892.
    • (2011) PLoS One , vol.6
    • Blagovic, K.1    Kim, L.Y.2    Voldman, J.3
  • 47
    • 84856385030 scopus 로고    scopus 로고
    • Attenuation of extrinsic signaling reveals the importance of matrix remodeling on maintenance of embryonic stem cell self-renewal
    • Przybyla LM, Voldman J. Attenuation of extrinsic signaling reveals the importance of matrix remodeling on maintenance of embryonic stem cell self-renewal. Proc Natl Acad Sci USA 2012;109:835-840.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 835-840
    • Przybyla, L.M.1    Voldman, J.2
  • 48
    • 84878412065 scopus 로고    scopus 로고
    • The role of paracrine and autocrine signaling in the early phase of adipogenic differentiation of adipose-derived stem cells
    • Hemmingsen M, Vedel S, Skafte-Pedersen P et al. The role of paracrine and autocrine signaling in the early phase of adipogenic differentiation of adipose-derived stem cells. PLoS ONE 2013;8:e63638.
    • (2013) PLoS ONE , vol.8
    • Hemmingsen, M.1    Vedel, S.2    Skafte-Pedersen, P.3
  • 49
    • 84893498597 scopus 로고    scopus 로고
    • Microbioreactor array screening to elucidate the role ofWntsignaling and microenvironmental factors in osteogenic differentiation of mesenchymal progenitor cells
    • (in press)
    • Frith J, Titmarsh D, Padmanabhan H et al. Microbioreactor array screening to elucidate the role ofWntsignaling and microenvironmental factors in osteogenic differentiation of mesenchymal progenitor cells. PLoS One 2013 (in press).
    • (2013) PLoS One
    • Frith, J.1    Titmarsh, D.2    Padmanabhan, H.3
  • 50
    • 84863011896 scopus 로고    scopus 로고
    • Rapid expansion of human hematopoietic stem cells by automated control of inhibitory feedback signaling
    • Csaszar E, Kirouac DC, Yu M et al. Rapid expansion of human hematopoietic stem cells by automated control of inhibitory feedback signaling. Cell Stem Cell 2012;10:218-229.
    • (2012) Cell Stem Cell , vol.10 , pp. 218-229
    • Csaszar, E.1    Kirouac, D.C.2    Yu, M.3
  • 51
    • 84861455412 scopus 로고    scopus 로고
    • A self-contained, programmable microfluidic cell culture system with realtime microscopy access
    • Skafte-Pedersen P, Hemmingsen M, Sabourin D et al. A self-contained, programmable microfluidic cell culture system with realtime microscopy access. Biomed Microdevices 2012;14:385-399.
    • (2012) Biomed Microdevices , vol.14 , pp. 385-399
    • Skafte-Pedersen, P.1    Hemmingsen, M.2    Sabourin, D.3
  • 53
    • 84863228077 scopus 로고    scopus 로고
    • Geometrical effects in microfluidic-based microarrays for rapid, efficient single-cell capture of mammalian stem cells and plant cells
    • Lawrenz A, Nason F, Cooper-White JJ. Geometrical effects in microfluidic-based microarrays for rapid, efficient single-cell capture of mammalian stem cells and plant cells. Biomicrofluidics 2012;6:24112-2411217.
    • (2012) Biomicrofluidics , vol.6 , pp. 24112-2411217
    • Lawrenz, A.1    Nason, F.2    Cooper-White, J.J.3
  • 54
    • 84855282436 scopus 로고    scopus 로고
    • Microwell perfusion array for high-throughput, long-term imaging of clonal growth
    • Chen H, Li J, Zhang H et al. Microwell perfusion array for high-throughput, long-term imaging of clonal growth. Biomicrofluidics 2011; 5:44117-4411713.
    • (2011) Biomicrofluidics , vol.5 , pp. 44117-4411713
    • Chen, H.1    Li, J.2    Zhang, H.3
  • 55
    • 84859150755 scopus 로고    scopus 로고
    • Single-cell level coculture platform for intercellular communication
    • Hong S, Pan Q, Lee LP. Single-cell level coculture platform for intercellular communication. Integr Biol (Camb) 2012;4:374-380.
    • (2012) Integr Biol (Camb) , vol.4 , pp. 374-380
    • Hong, S.1    Pan, Q.2    Lee, L.P.3
  • 56
    • 80052487012 scopus 로고    scopus 로고
    • Estimating the risk of drug-induced proarrhythmia using human induced pluripotent stem cellderived cardiomyocytes
    • Guo L, Abrams RM, Babiarz JE et al. Estimating the risk of drug-induced proarrhythmia using human induced pluripotent stem cellderived cardiomyocytes. Toxicol Sci 2011;123: 281-289.
    • (2011) Toxicol Sci , vol.123 , pp. 281-289
    • Guo, L.1    Abrams, R.M.2    Babiarz, J.E.3
  • 57
    • 84880678710 scopus 로고    scopus 로고
    • Comparison of electrophysiological data from humaninduced pluripotent stem cell-derived cardiomyocytes to functional preclinical safety assays
    • Harris K, Aylott M, Cui Y et al. Comparison of electrophysiological data from humaninduced pluripotent stem cell-derived cardiomyocytes to functional preclinical safety assays. Toxicol Sci 2013;134:412-426.
    • (2013) Toxicol Sci , vol.134 , pp. 412-426
    • Harris, K.1    Aylott, M.2    Cui, Y.3
  • 58
    • 79955633316 scopus 로고    scopus 로고
    • Realtime label-free monitoring of adipose-derived stem cell differentiation with electric cellsubstrate impedance sensing
    • Bagnaninchi PO, Drummond N. Realtime label-free monitoring of adipose-derived stem cell differentiation with electric cellsubstrate impedance sensing. Proc Natl Acad Sci USA 2011;108:6462-6467.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 6462-6467
    • Bagnaninchi, P.O.1    Drummond, N.2
  • 59
    • 84870911361 scopus 로고    scopus 로고
    • Labelfree electrophysiological cytometry for stem cell-derived cardiomyocyte clusters
    • Myers FB, Zarins CK, Abilez OJ et al. Labelfree electrophysiological cytometry for stem cell-derived cardiomyocyte clusters. Lab Chip 2013;13:220-228.
    • (2013) Lab Chip , vol.13 , pp. 220-228
    • Myers, F.B.1    Zarins, C.K.2    Abilez, O.J.3
  • 60
    • 84878037451 scopus 로고    scopus 로고
    • Amicrofluidic impedance flow cytometer for identification of differentiation state of stem cells
    • Song H, WangY, RosanoJMet al. Amicrofluidic impedance flow cytometer for identification of differentiation state of stem cells. Lab Chip 2013;13:2300-2310.
    • (2013) Lab Chip , vol.13 , pp. 2300-2310
    • Song, H.1    Wang, Y.2    Rosano, J.M.3
  • 61
    • 84861882789 scopus 로고    scopus 로고
    • Microfluidic encapsulation of cells in polymer microgels
    • Velasco D, Tumarkin E, Kumacheva E. Microfluidic encapsulation of cells in polymer microgels. Small 2012;8:1633-1642.
    • (2012) Small , vol.8 , pp. 1633-1642
    • Velasco, D.1    Tumarkin, E.2    Kumacheva, E.3
  • 62
    • 84875972294 scopus 로고    scopus 로고
    • Microfluidic synthesis of cell-type-specific artificial extracellular matrix hydrogels
    • Allazetta S, Hausherr TC, Lutolf MP. Microfluidic synthesis of cell-type-specific artificial extracellular matrix hydrogels. Biomacromolecules 2013;14:1122-1131.
    • (2013) Biomacromolecules , vol.14 , pp. 1122-1131
    • Allazetta, S.1    Hausherr, T.C.2    Lutolf, M.P.3
  • 63
    • 82555202738 scopus 로고    scopus 로고
    • Microfluidic fabrication of microengineered hydrogels and their application in tissue engineering
    • Chung BG, Lee KH, Khademhosseini A et al. Microfluidic fabrication of microengineered hydrogels and their application in tissue engineering. Lab Chip 2012;12:45-59.
    • (2012) Lab Chip , vol.12 , pp. 45-59
    • Chung, B.G.1    Lee, K.H.2    Khademhosseini, A.3
  • 64
    • 84862231072 scopus 로고    scopus 로고
    • Commercialization of microfluidic point-of-care diagnostic devices
    • Chin CD, Linder V, Sia SK. Commercialization of microfluidic point-of-care diagnostic devices. Lab Chip 2012;12:2118-2134.
    • (2012) Lab Chip , vol.12 , pp. 2118-2134
    • Chin, C.D.1    Linder, V.2    Sia, S.K.3
  • 65
    • 84874513001 scopus 로고    scopus 로고
    • Microfluidics and circulating tumor cells
    • Dong Y, Skelley AM, Merdek KD et al. Microfluidics and circulating tumor cells. J Mol Diagn 2013;15:149-157.
    • (2013) J Mol Diagn , vol.15 , pp. 149-157
    • Dong, Y.1    Skelley, A.M.2    Merdek, K.D.3
  • 66
    • 84870700980 scopus 로고    scopus 로고
    • Stem cells. U.S. regulation of stem cells as medical products
    • Sipp D, Turner L. Stem cells. U.S. regulation of stem cells as medical products. Science 2012;338:1296-1297.
    • (2012) Science , vol.338 , pp. 1296-1297
    • Sipp, D.1    Turner, L.2
  • 67
    • 84872088799 scopus 로고    scopus 로고
    • The meaning, the sense and the significance: Translating the science of mesenchymal stem cells into medicine
    • Bianco P, Cao X, Frenette PS et al. The meaning, the sense and the significance: Translating the science of mesenchymal stem cells into medicine. Nat Med 2013;19: 35-42.
    • (2013) Nat Med , vol.19 , pp. 35-42
    • Bianco, P.1    Cao, X.2    Frenette, P.S.3
  • 68
    • 77949324607 scopus 로고    scopus 로고
    • Cellular observations enabled by microculture: Paracrine signaling and population demographics
    • Domenech M, Yu H, Warrick J et al. Cellular observations enabled by microculture: Paracrine signaling and population demographics. Integr Biol (Camb) 2009;1: 267-274.
    • (2009) Integr Biol (Camb) , vol.1 , pp. 267-274
    • Domenech, M.1    Yu, H.2    Warrick, J.3
  • 69
    • 84859602728 scopus 로고    scopus 로고
    • Microfluidic single-cell real-time PCR for comparative analysis of gene expression patterns
    • Sanchez-Freire V, Ebert AD, Kalisky T et al. Microfluidic single-cell real-time PCR for comparative analysis of gene expression patterns. Nat Protoc 2012;7:829-838.
    • (2012) Nat Protoc , vol.7 , pp. 829-838
    • Sanchez-Freire, V.1    Ebert, A.D.2    Kalisky, T.3
  • 70
    • 45849087630 scopus 로고    scopus 로고
    • High throughput gene expression measurement with real time PCR in a microfluidic dynamic array
    • Spurgeon SL, Jones RC, Ramakrishnan R. High throughput gene expression measurement with real time PCR in a microfluidic dynamic array. PLoS One 2008;3:e1662.
    • (2008) PLoS One , vol.3
    • Spurgeon, S.L.1    Jones, R.C.2    Ramakrishnan, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.