A self-contained, programmable microfluidic cell culture system with real-time microscopy access

Biomedical Microdevices

Volumn 14, Issue 2, 2012, Pages 385-399

  Skafte Pedersen, Peder ^a   Hemmingsen, Mette ^a   Sabourin, David ^a   Blaga, Felician Stefan ^a   Bruus, Henrik ^a   Dufva, Martin ^a  

^a TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

Author keywords

Cell culture; Microfluidic; Modular; Portable; Programmable; User friendly

Indexed keywords

AUTOMATED CELL; BIOLOGICAL ASSAYS; CELL BIOLOGY; CONSTRUCTION PRINCIPLE; HIGHLY-PORTABLE; INLET CHANNELS; MICROFLUIDIC CELL CULTURE; MODULAR; MODULAR APPROACH; ON CHIPS; ON-CHIP PASSIVES; PORTABLE; PROGRAMMABLE; SINGLE CHIPS; SYSTEM'S PERFORMANCE; USER-FRIENDLY; WORK STATION;

CELL CULTURE; GENE EXPRESSION; LAMINAR FLOW; MOLECULAR BIOLOGY;

MICROFLUIDICS;

ARTICLE; AUTOMATION; BIOASSAY; CELL CULTURE; COMPUTER PROGRAM; CONTROLLED STUDY; FINITE ELEMENT ANALYSIS; GENE EXPRESSION; HELA CELL; HUMAN; HUMAN CELL; INCUBATOR; LAB ON A CHIP; LAMINAR FLOW; MATHEMATICAL MODEL; MICROFLUIDIC ANALYSIS; MICROSCOPE; MICROSCOPY; PRIORITY JOURNAL; REAL TIME MICROSCOPY; REPORTER GENE;

CELL CULTURE TECHNIQUES; EQUIPMENT DESIGN; GENE EXPRESSION REGULATION; HELA CELLS; HUMANS; MICROFLUIDIC ANALYTICAL TECHNIQUES; MICROFLUIDICS; MICROSCOPY; REPRODUCIBILITY OF RESULTS; TRANSFECTION;

EID: 84861455412     PISSN: 13872176     EISSN: 15728781     Source Type: Journal    
DOI: 10.1007/s10544-011-9615-6     Document Type: Article

References (41)

1. H. Andersson, A. van den Berg, Lab on a Chip 6, 467-470 (2006)
2. L.A. Banaszynski, L.-C. Chen, L.A. Maynard-Smith, A.G.L. Ooi, T.J. Wandless, Cell 126, 995-1004 (2006)
3. A. Bancaud, G. Wagner, K.D. Dorfman, J.-L. Viovy, Anal. Chem. 77, 833-839 (2005)
4. A. Buchenauer, M. Funke, J. Büchs, W. Mokwa, U. Schnakenberg, J. Micromech. Microeng. 19, 074012 (2009)
5. A.J. Conde, D. Sabourin, P. Skafte-Pedersen and M. Dufva, Proceedings of the 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences (uTAS2011), 2-6 October 2011, Seattle,Washington, USA, eds. J.P. Landers, A. Herr, D. Juncker, N. Pamme, and J. Bienvenue, (CBMS, 2011) pp. 1621-1623 (2011)
6. N. Futai, W. Gu, J.W. Song, S. Takayama, Lab on a Chip 6, 149-154 (2006)
7. R. Gomez-Sjöberg, A.A. Leyrat, D.M. Pirone, C.S. Chen, S.R. Quake, Anal. Chem. 79, 8557-8563 (2007)
8. W. Gu, X. Zhu, N. Futai, B.S. Cho, S. Takayama, PNAS 101, 15861-15866 (2004)
9. M. Hemmingsen, P. Skafte-Pedersen, D. Sabourin, R.F. Andersen, A.L. Sørensen, P. Collas and M. Dufva, Proceedings of the 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences (uTAS2011), 2-6 October 2011, Seattle, Washington, USA, eds. J.P. Landers, A. Herr, D. Juncker, N. Pamme, and J. Bienvenue, (CBMS, 2011) pp. 834-836 (2011)
10. C.-C. Hsieh, S.-B. Huang, D.-B. Shieh, G.-B. Lee, P.-C. Wu, G.-B. Lee, Biomedical Microdevices 11, 903-913 (2009)
11. P.J. Hung, P.J. Lee, P. Sabounchi, R. Lin, L.P. Lee, Biotechnol. Bioeng. 89, 1-8 (2005)
12. L. Kim, M.D. Vahey, H.-Y. Lee, J. Voldman, Lab on a Chip 6, 394-406 (2006)
13. J.Y. Kim, H. Park, K.H. Kwon, J.Y. Park, J.Y. Baek, T.S. Lee, H.R. Song, Y.D. Park, S.H. Lee, Biomedical Microdevices 10, 11-20 (2008)
14. K.R. King, S. Wang, D. Irimia, A. Jayaraman, M. Toner, M.L. Yarmush, Lab on a Chip 7, 77-85 (2006)
15. Y.-K. Lee, P. Tabeling, C. Shih and C.-M. Ho, Proceedings of the ASME International Mechanical Engineering Congress and Exposition, November 5-10, 2000, Orlando, Florida, USA, pp. 505-511 (2000)
16. P.J. Lee, N. Ghorashian, T.A. Gaige, P.J. Hung, J. Assoc. Lab. Autom. 12, 363-367 (2007)
17. S. Lindström, M. Eriksson, T. Vazin, J. Sandberg, J. Lundeberg, J. Frisén and H. Andersson-Svahn, PLOS ONE 4, -, (2009)
18. M. Liu and Y.-C. Tai, Biomedical Microdevices, 1-11, (2010)
19. J. Melin, S.R. Quake, Annu. Rev. Biophys. Biomol. Struct. 36, 213-231 (2007)
20. I. Meyvantsson, J.W.Warrick, S. Hayes, A. Skoien, D.J. Beebe, Lab on a Chip 8, 717-724 (2008)
21. J.Y. Park, S. Takayama, S.-H. Lee, Integr. Biol. 2, 229-240 (2010)
22. S. Petronis, M. Stangegaard, C.B.V. Christensen, M. Dufva, Biotechniques 40, 368-376 (2006)
23. J.P. Puccinelli, X. Su, D.J. Beebe, J. Assoc. Lab. Autom. 15, 25-32 (2010)
24. S.A. Rani, B. Pitts, P.S. Stewart, Antimicrob. Agents Chemother. 49, 728-732 (2005)
25. D. Sabourin, D. Snakenborg, M. Dufva, Microfluidics and Nanofluidics 9, 87-93 (2010a)
26. D. Sabourin, P. Skafte-Pedersen, V. Coman, M. Hemmingsen, J. Petersen, J.P. Kutter, J. Emneus, D. Snakenborg and M. Dufva, Proceedings of the 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences (uTAS2010), 3-7 October 2010, Groningen, The Netherlands, eds. S. Verporte, H. Andersson, J. Emneus, and N. Pamme (CBMS, 2010) pp. 166-168 (2010b)
27. P. Skafte-Pedersen, D. Sabourin, M. Dufva, D. Snakenborg, Lab on a Chip 9, 3003-3006 (2009)
28. M. Stangegaard, S. Petronis, A.M. Jørgensen, C.B.V. Christensen, M. Dufva, Lab on a Chip 6, 1045-1051 (2006)
29. S. Sugiura, J.-I. Edahiro, K. Kikuchi, K. Sumaru, T. Kanamori, Biotechnol. Bioeng. 100, 1156-1165 (2008)
30. R.J. Taylor, D. Falconnet, A. Niemistö, S.A. Ramsey, S. Prinz, I. Shmulevich, T. Galitski, C.L. Hansen, Proc. Natl. Acad. Sci. 106, 3758-3763 (2009)
31. R. Truckenmüller, P. Henzi, D. Herrmann, V. Saile, W.K. Schomburg, Microsyst. Technol. 10, 372-374 (2004)
32. Y.-C. Tung, Y.-S. Torisawa, N. Futai, S. Takayama, Lab on a Chip 7, 1497-1503 (2007)
33. G. Velve-Casquillas, M.L. Berre, M. Piel, P.T. Tran, Nano Today 5, 28-47 (2010)
34. Z. Wang, M.-C. Kim, M. Marquez, T. Thorsen, Lab on a Chip 7, 740-745 (2007)
35. G.M. Whitesides, Lab on a Chip 11, 191-193 (2011)
36. M.-H. Wu, S.-B. Huang, G.-B. Lee, Lab on a Chip 10, 939-956 (2010)
37. J.H. Yeon, J.-K. Park, Biochip Journal 1, 17-27 (2007)
38. E.W.K. Young, D.J. Beebe, Chem. Soc. Rev. 39, 1036-1048 (2010)
39. E.W.K. Young, C.A. Simmons, Lab on a Chip 10, 143-160 (2009)
40. Z.T.F. Yu, Z.T.F. Yu, K.-I. Kamei, H. Takahashi, X.Wang, G.W. He, C. G. Radu, H.-R. Tseng, Z.T.F. Yu, K.-I. Kamei, G.W. He, R. Silverman, C.G. Radu, O.N. Witte, C.J. Shu, O.N. Witte, O.N. Witte, K.-B. Lee, Biomedical Microdevices 11, 547-555 (2009)
41. B. Zhang, M.-C. Kim, T. Thorsen, Z. Wang, Biomedical Microdevices 11, 1233-1237 (2009)