Patterning pluripotency in embryonic stem cells

Stem Cells

Volumn 31, Issue 9, 2013, Pages 1806-1815

  Zhang, Yue Shelby ^a   Sevilla, Ana ^b,c   Wan, Leo Q ^a,d   Lemischka, Ihor R ^b   Vunjak Novakovic, Gordana ^a  

^a Fu Foundation School of Engineering and Applied Science   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c The New York Stem Cell Foundation Research Institute   (United States)

^d RENSSELAER POLYTECHNIC INSTITUTE   (United States)

Author keywords

Differentiation; Embryonic stem cells; Experimental models; Pluripotency; Stem cell microenvironment interactions; Technology; Tissue regeneration

Indexed keywords

TRANSCRIPTION FACTOR NANOG;

ARTICLE; BLASTOCYST; CELL POPULATION; CONTROLLED STUDY; EMBRYONIC STEM CELL; GENE EXPRESSION; IN VITRO STUDY; MICROFLUIDICS; NONHUMAN; PROTEIN EXPRESSION;

DIFFERENTIATION; EMBRYONIC STEM CELLS; EXPERIMENTAL MODELS; PLURIPOTENCY; STEM CELL-MICROENVIRONMENT INTERACTIONS; TECHNOLOGY; TISSUE REGENERATION;

ANIMALS; CELL DIFFERENTIATION; CELL LINE; COLONY-FORMING UNITS ASSAY; DOXYCYCLINE; EMBRYONIC STEM CELLS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HOMEODOMAIN PROTEINS; HUMANS; LEUKEMIA INHIBITORY FACTOR; MICE; MICROFLUIDICS; MODELS, BIOLOGICAL; PLURIPOTENT STEM CELLS; TRETINOIN;

EID: 84884412620     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.1468     Document Type: Article

References (46)

1. Nichols J, Zevnik B, Anastassiadis K, et al. Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4. Cell 1998; 95: 379-391.
2. Niwa H, Miyazaki J, Smith AG,. Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells. Nat Genet 2000; 24: 372-376.
3. Chambers I, Colby D, Robertson M, et al. Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells. Cell 2003; 113: 643-655.
4. Mitsui K, Tokuzawa Y, Itoh H, et al. The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell 2003; 113: 631-642.
5. Niwa H, Burdon T, Chambers I, et al. Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3. Genes Dev 1998; 12: 2048-2060.
6. Ying QL, Nichols J, Chambers I, et al. BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3. Cell 2003; 115: 281-292.
7. Burdon T, Stracey C, Chambers I, et al. Suppression of SHP-2 and ERK signalling promotes self-renewal of mouse embryonic stem cells. Dev Biol 1999; 210: 30-43.
8. Sato N, Meijer L, Skaltsounis L, et al. Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor. Nat Med 2004; 10: 55-63.
9. Meinhardt H,. Cell determination boundaries as organizing regions for secondary embryonic fields. Dev Biol 1983; 96: 375-385.
10. Monier B, Pélissier-Monier A, Brand AH, et al. An actomyosin-based barrier inhibits cell mixing at compartmental boundaries in Drosophila embryos. Nat Cell Biol 2010; 12: 60-65; supp 1-9.
11. Landsberg KP, Farhadifar R, Ranft J et al. Increased cell bond tension governs cell sorting at the Drosophila anteroposterior compartment boundary. Curr Biol 2009; 19: 1950-1955.
12. Ruiz SA, Chen CS,. Emergence of patterned stem cell differentiation within multicellular structures. Stem Cells 2008; 26: 2921-2927.
13. Phillippi JA, Miller E, Weiss L, et al. Microenvironments engineered by inkjet bioprinting spatially direct adult stem cells toward muscle- and bone-like subpopulations. Stem Cells 2008; 26: 127-134.
14. Zhang Y, Gazit Z, Pelled G, et al. Patterning osteogenesis by inducible gene expression in microfluidic culture systems. Integr Biol (Camb) 2011; 3: 39-47.
15. Chambers I, Silva J, Colby D et al. Nanog safeguards pluripotency and mediates germline development. Nature 2007; 450: 1230-1234.
16. Lu R, Markowetz F, Unwin RD, et al. Systems-level dynamic analyses of fate change in murine embryonic stem cells. Nature 2009; 462: 358-362.
17. Ivanova N, Dobrin R, Lu R, et al. Dissecting self-renewal in stem cells with RNA interference. Nature 2006; 442: 533-538.
18. Lee DF, Su J, Sevilla A et al. Combining competition assays with genetic complementation strategies to dissect mouse embryonic stem cell self-renewal and pluripotency. Nat Protoc 2012; 7: 729-748.
19. Singh AM, Hamazaki T, Hankowski KE et al. A heterogeneous expression pattern for Nanog in embryonic stem cells. Stem Cells 2007; 25: 2534-2542.
20. Ting DT, Kyba M, Daley GQ,. Inducible transgene expression in mouse stem cells. Methods Mol Med 2005; 105: 23-46.
21. Atkinson B, Brocklebank MP, Card CCH, et al. Low Reynolds number developing flows. AIChE J 1969; 15: 548-553.
22. Frederickson R,. Fluidigm: Biochips get indoor plumbing. Chem Biol 2002; 9: 1161-1162.
23. Loh YH, Wu Q, Chew JL, et al. The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells. Nat Genet 2006; 38: 431-440.
24. Cole MF, Johnstone SE, Newman JJ, et al. Tcf3 is an integral component of the core regulatory circuitry of embryonic stem cells. Genes Dev 2008; 22: 746-755.
25. Marson A, Levine SS, Cole MF, et al. Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells. Cell 2008; 134: 521-533.
26. Kim J, Chu J, Shen X et al. An extended transcriptional network for pluripotency of embryonic stem cells. Cell 2008; 132: 1049-1061.
27. Chen X, Xu H, Yuan P et al. Integration of external signaling pathways with the core transcriptional network in embryonic stem cells. Cell 2008; 133: 1106-1117.
28. Mathur D, Danford TW, Boyer LA, et al. Analysis of the mouse embryonic stem cell regulatory networks obtained by ChIP-chip and ChIP-PET. Genome Biol 2008; 9: R126.
29. Ayroles JF, Gibson G,. Analysis of variance of microarray data. Methods Enzymol 2006; 411: 214-233.
30. Hebert JM, Boyle M, Martin GR,. mRNA localization studies suggest that murine FGF-5 plays a role in gastrulation. Development 1991; 112: 407-415.
31. Serls AE, Doherty S, Parvatiyar P, et al. Different thresholds of fibroblast growth factors pattern the ventral foregut into liver and lung. Development 2005; 132: 35-47.
32. Wang DM, Tarbell JM,. Modeling interstitial flow in an artery wall allows estimation of wall shear stress on smooth muscle cells. J Biomech Eng 1995; 117: 358-363.
33. Fujikura J, Yamato E, Yonemura S, et al. Differentiation of embryonic stem cells is induced by GATA factors. Genes Dev 2002; 16: 784-789.
34. Morrisey EE, Tang Z, Sigrist K, et al. GATA6 regulates HNF4 and is required for differentiation of visceral endoderm in the mouse embryo. Genes Dev 1998; 12: 3579-3590.
35. Koutsourakis M, Langeveld A, Patient R et al. The transcription factor GATA6 is essential for early extraembryonic development. Development 1999; 126: 723-732.
36. Ang YS, Tsai SY, Lee DF, et al. Wdr5 mediates self-renewal and reprogramming via the embryonic stem cell core transcriptional network. Cell 2011; 145: 183-197.
37. Baumann K,. Reprogramming: Remodelling for pluripotency. Nat Rev Mol Cell Biol 2010; 11: 540-541.
38. Niwa H,. Open conformation chromatin and pluripotency. Genes Dev 2007; 21: 2671-2676.
39. Ho L, Ronan JL, Wu J, et al. An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency. Proc Natl Acad Sci USA 2009; 106: 5181-5186.
40. Mann RS, Morata G,. The developmental and molecular biology of genes that subdivide the body of Drosophila. Annu Rev Cell Dev Biol 2000; 16: 243-271.
41. Tremblay KD, Zaret KS,. Distinct populations of endoderm cells converge to generate the embryonic liver bud and ventral foregut tissues. Dev Biol 2005; 280: 87-99.
42. Kulesa PM, Fraser SE,. Cell dynamics during somite boundary formation revealed by time-lapse analysis. Science 2002; 298: 991-995.
43. Dahmann C, Oates AC, Brand M,. Boundary formation and maintenance in tissue development. Nat Rev Genet 2011; 12: 43-55.
44. Alexander T, Nolte C, Krumlauf R,. Hox genes and segmentation of the hindbrain and axial skeleton. Annu Rev Cell Dev Biol 2009; 25: 431-456.
45. Ho L, Jothi R, Ronan JL, et al. An embryonic stem cell chromatin remodeling complex, esBAF, is an essential component of the core pluripotency transcriptional network. Proc Natl Acad Sci USA 2009; 106: 5187-5191.
46. Cai KQ, Capo-Chichi CD, Rula ME, et al. Dynamic GATA6 expression in primitive endoderm formation and maturation in early mouse embryogenesis. Dev Dyn 2008; 237: 2820-2829.