메뉴 건너뛰기




Volumn 115, Issue 3, 2014, Pages 498-509

ErbB2 activation upregulates glutaminase 1 expression which promotes breast cancer cell proliferation

Author keywords

BREAST CANCER; ErbB2; GLS1; GLUTAMINASE; GLUTAMINE; NUCLEAR FACTOR B

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; GLUTAMINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MYC PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B;

EID: 84892717735     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.24684     Document Type: Article
Times cited : (77)

References (54)
  • 1
    • 0030890933 scopus 로고    scopus 로고
    • Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase
    • Ahmed NN, Grimes HL, Bellacosa A, Chan TO, Tsichlis PN,. 1997. Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase. Proc Natl Acad Sci USA 94: 3627-3632.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 3627-3632
    • Ahmed, N.N.1    Grimes, H.L.2    Bellacosa, A.3    Chan, T.O.4    Tsichlis, P.N.5
  • 2
    • 0033661413 scopus 로고    scopus 로고
    • Identification of two human glutaminase loci and tissue-specific expression of the two related genes
    • Aledo JC, Gomez-Fabre PM, Olalla L, Marquez J,. 2000. Identification of two human glutaminase loci and tissue-specific expression of the two related genes. Mamm Genome 11: 1107-1110.
    • (2000) Mamm Genome , vol.11 , pp. 1107-1110
    • Aledo, J.C.1    Gomez-Fabre, P.M.2    Olalla, L.3    Marquez, J.4
  • 3
    • 67649472398 scopus 로고    scopus 로고
    • Novel anticancer targets: Revisiting ERBB2 and discovering ERBB3
    • Baselga J, Swain SM,. 2009. Novel anticancer targets: Revisiting ERBB2 and discovering ERBB3. Nat Rev Cancer 9: 463-475.
    • (2009) Nat Rev Cancer , vol.9 , pp. 463-475
    • Baselga, J.1    Swain, S.M.2
  • 4
    • 47749101220 scopus 로고    scopus 로고
    • Inflammation and cancer: The oncogene-driven connection
    • Borrello MG, Degl'Innocenti D, Pierotti MA,. 2008. Inflammation and cancer: The oncogene-driven connection. Cancer Lett 267: 262-270.
    • (2008) Cancer Lett , vol.267 , pp. 262-270
    • Borrello, M.G.1    Degl'Innocenti, D.2    Pierotti, M.A.3
  • 5
    • 80755163690 scopus 로고    scopus 로고
    • Breast cancer: Current state and future promise
    • Chodosh LA,. 2011. Breast cancer: Current state and future promise. Breast Cancer Res 13: 113.
    • (2011) Breast Cancer Res , vol.13 , pp. 113
    • Chodosh, L.A.1
  • 6
    • 0028124832 scopus 로고
    • An increase in p50/p65 NF-κB binding to the HIV-1 LTR is not sufficient to increase viral expression in the primary human astrocyte
    • Conant K, Atwood WJ, Traub R, Tornatore C, Major EO,. 1994. An increase in p50/p65 NF-κB binding to the HIV-1 LTR is not sufficient to increase viral expression in the primary human astrocyte. Virology 205: 586-590.
    • (1994) Virology , vol.205 , pp. 586-590
    • Conant, K.1    Atwood, W.J.2    Traub, R.3    Tornatore, C.4    Major, E.O.5
  • 8
    • 77958492734 scopus 로고    scopus 로고
    • Glutaminolysis: Supplying carbon or nitrogen or both for cancer cells
    • Dang CV,. 2010. Glutaminolysis: Supplying carbon or nitrogen or both for cancer cells ? Cell Cycle 9: 3884-3886.
    • (2010) Cell Cycle , vol.9 , pp. 3884-3886
    • Dang, C.V.1
  • 11
    • 75149148563 scopus 로고    scopus 로고
    • Q's next: The diverse functions of glutamine in metabolism, cell biology and cancer
    • DeBerardinis RJ, Cheng T,. 2010. Q's next: The diverse functions of glutamine in metabolism, cell biology and cancer. Oncogene 29: 313-324.
    • (2010) Oncogene , vol.29 , pp. 313-324
    • Deberardinis, R.J.1    Cheng, T.2
  • 13
    • 65649091305 scopus 로고    scopus 로고
    • Emerging drugs in metastatic breast cancer
    • Dizdar O, Altundag K,. 2009. Emerging drugs in metastatic breast cancer. Expert Opin Emerg Drugs 14: 85-98.
    • (2009) Expert Opin Emerg Drugs , vol.14 , pp. 85-98
    • Dizdar, O.1    Altundag, K.2
  • 14
    • 79957991472 scopus 로고    scopus 로고
    • Glutaminase: A hot spot for regulation of cancer cell metabolism
    • Erickson JW, Cerione RA,. 2010. Glutaminase: a hot spot for regulation of cancer cell metabolism ? Oncotarget 1: 734-740.
    • (2010) Oncotarget , vol.1 , pp. 734-740
    • Erickson, J.W.1    Cerione, R.A.2
  • 15
    • 77958510718 scopus 로고    scopus 로고
    • RB-pathway disruption in breast cancer: Differential association with disease subtypes, disease-specific prognosis and therapeutic response
    • Ertel A, Dean JL, Rui H, Liu C, Witkiewicz AK, Knudsen KE, Knudsen ES,. 2010. RB-pathway disruption in breast cancer: differential association with disease subtypes, disease-specific prognosis and therapeutic response. Cell Cycle 9: 4153-4163.
    • (2010) Cell Cycle , vol.9 , pp. 4153-4163
    • Ertel, A.1    Dean, J.L.2    Rui, H.3    Liu, C.4    Witkiewicz, A.K.5    Knudsen, K.E.6    Knudsen, E.S.7
  • 16
    • 0029932755 scopus 로고    scopus 로고
    • Oncogenic Neu/ErbB-2 increases ets, AP-1, and NF-kappaB-dependent gene expression, and inhibiting ets activation blocks Neu-mediated cellular transformation
    • Galang CK, Garcia-Ramirez J, Solski PA, Westwick JK, Der CJ, Neznanov NN, Oshima RG, Hauser CA,. 1996. Oncogenic Neu/ErbB-2 increases ets, AP-1, and NF-kappaB-dependent gene expression, and inhibiting ets activation blocks Neu-mediated cellular transformation. J Biol Chem 271: 7992-7998.
    • (1996) J Biol Chem , vol.271 , pp. 7992-7998
    • Galang, C.K.1    Garcia-Ramirez, J.2    Solski, P.A.3    Westwick, J.K.4    Der, C.J.5    Neznanov, N.N.6    Oshima, R.G.7    Hauser, C.A.8
  • 18
    • 0032895235 scopus 로고    scopus 로고
    • Trastuzumab, a recombinant DNA-derived humanized monoclonal antibody, a novel agent for the treatment of metastatic breast cancer
    • Goldenberg MM,. 1999. Trastuzumab, a recombinant DNA-derived humanized monoclonal antibody, a novel agent for the treatment of metastatic breast cancer. Clin Ther 21: 309-318.
    • (1999) Clin Ther , vol.21 , pp. 309-318
    • Goldenberg, M.M.1
  • 20
    • 78649732997 scopus 로고    scopus 로고
    • Anti-HER2 neoadjuvant and adjuvant therapies in HER2 positive breast cancer
    • Guarneri V, Barbieri E, Dieci MV, Piacentini F, Conte P,. 2010. Anti-HER2 neoadjuvant and adjuvant therapies in HER2 positive breast cancer. Cancer Treat Rev 36 (Suppl 3): S62-S66.
    • (2010) Cancer Treat Rev , vol.36 , Issue.SUPPL. 3
    • Guarneri, V.1    Barbieri, E.2    Dieci, M.V.3    Piacentini, F.4    Conte, P.5
  • 21
    • 18344390418 scopus 로고    scopus 로고
    • ERBB receptors and cancer: The complexity of targeted inhibitors
    • Hynes NE, Lane HA,. 2005. ERBB receptors and cancer: the complexity of targeted inhibitors. Nat Rev Cancer 5: 341-354.
    • (2005) Nat Rev Cancer , vol.5 , pp. 341-354
    • Hynes, N.E.1    Lane, H.A.2
  • 22
    • 63749086305 scopus 로고    scopus 로고
    • ErbB receptors and signaling pathways in cancer
    • Hynes NE, MacDonald G,. 2009. ErbB receptors and signaling pathways in cancer. Curr Opin Cell Biol 21: 177-184.
    • (2009) Curr Opin Cell Biol , vol.21 , pp. 177-184
    • Hynes, N.E.1    Macdonald, G.2
  • 24
    • 43049139541 scopus 로고    scopus 로고
    • P53 regulates glucose metabolism through an IKK-NF-kappaB pathway and inhibits cell transformation
    • Kawauchi K, Araki K, Tobiume K, Tanaka N,. 2008. p53 regulates glucose metabolism through an IKK-NF-kappaB pathway and inhibits cell transformation. Nat Cell Biol 10: 611-618.
    • (2008) Nat Cell Biol , vol.10 , pp. 611-618
    • Kawauchi, K.1    Araki, K.2    Tobiume, K.3    Tanaka, N.4
  • 25
    • 34247225990 scopus 로고    scopus 로고
    • Down-regulation of glutaminase C in human hepatocarcinoma cell by diphenylarsinic acid, a degradation product of chemical warfare agents
    • Kita K, Suzuki T, Ochi T,. 2007. Down-regulation of glutaminase C in human hepatocarcinoma cell by diphenylarsinic acid, a degradation product of chemical warfare agents. Toxicol Appl Pharmacol 220: 262-270.
    • (2007) Toxicol Appl Pharmacol , vol.220 , pp. 262-270
    • Kita, K.1    Suzuki, T.2    Ochi, T.3
  • 27
    • 0022570332 scopus 로고
    • 6-Diazo-5-oxo-L-norleucine and azaserine as affinity inhibitors of glutamin(asparagin)ase
    • Lebedeva ZI, Kabanova EA, Berezov TT,. 1986. 6-Diazo-5-oxo-L-norleucine and azaserine as affinity inhibitors of glutamin(asparagin)ase. Biochem Int 12: 413-420.
    • (1986) Biochem Int , vol.12 , pp. 413-420
    • Lebedeva, Z.I.1    Kabanova, E.A.2    Berezov, T.T.3
  • 28
    • 78649711427 scopus 로고    scopus 로고
    • The control of the metabolic switch in cancers by oncogenes and tumor suppressor genes
    • Levine AJ, Puzio-Kuter AM,. 2010. The control of the metabolic switch in cancers by oncogenes and tumor suppressor genes. Science 330: 1340-1344.
    • (2010) Science , vol.330 , pp. 1340-1344
    • Levine, A.J.1    Puzio-Kuter, A.M.2
  • 31
    • 77958478353 scopus 로고    scopus 로고
    • Nitrogen anabolism underlies the importance of glutaminolysis in proliferating cells
    • Meng M, Chen S, Lao T, Liang D, Sang N,. 2010. Nitrogen anabolism underlies the importance of glutaminolysis in proliferating cells. Cell Cycle 9: 3921-3932.
    • (2010) Cell Cycle , vol.9 , pp. 3921-3932
    • Meng, M.1    Chen, S.2    Lao, T.3    Liang, D.4    Sang, N.5
  • 32
    • 77649190700 scopus 로고    scopus 로고
    • Her2 activates NF-kappaB and induces invasion through the canonical pathway involving IKKalpha
    • Merkhofer EC, Cogswell P, Baldwin AS,. 2010. Her2 activates NF-kappaB and induces invasion through the canonical pathway involving IKKalpha. Oncogene 29: 1238-1248.
    • (2010) Oncogene , vol.29 , pp. 1238-1248
    • Merkhofer, E.C.1    Cogswell, P.2    Baldwin, A.S.3
  • 34
    • 0034600849 scopus 로고    scopus 로고
    • The ErbB signaling network: Receptor heterodimerization in development and cancer
    • Olayioye MA, Neve RM, Lane HA, Hynes NE,. 2000. The ErbB signaling network: receptor heterodimerization in development and cancer. EMBO J 19: 3159-3167.
    • (2000) EMBO J , vol.19 , pp. 3159-3167
    • Olayioye, M.A.1    Neve, R.M.2    Lane, H.A.3    Hynes, N.E.4
  • 36
    • 0035868342 scopus 로고    scopus 로고
    • Her-2/neu overexpression induces NF-kappaB via a PI3-kinase/Akt pathway involving calpain-mediated degradation of IkappaB-alpha that can be inhibited by the tumor suppressor PTEN
    • Pianetti S, Arsura M, Romieu-Mourez R, Coffey RJ, Sonenshein GE,. 2001. Her-2/neu overexpression induces NF-kappaB via a PI3-kinase/Akt pathway involving calpain-mediated degradation of IkappaB-alpha that can be inhibited by the tumor suppressor PTEN. Oncogene 20: 1287-1299.
    • (2001) Oncogene , vol.20 , pp. 1287-1299
    • Pianetti, S.1    Arsura, M.2    Romieu-Mourez, R.3    Coffey, R.J.4    Sonenshein, G.E.5
  • 37
    • 0030772376 scopus 로고    scopus 로고
    • Novel inhibitors of cytokine-induced IkappaBalpha phosphorylation and endothelial cell adhesion molecule expression show anti-inflammatory effects in vivo
    • Pierce JW, Schoenleber R, Jesmok G, Best J, Moore SA, Collins T, Gerritsen ME,. 1997. Novel inhibitors of cytokine-induced IkappaBalpha phosphorylation and endothelial cell adhesion molecule expression show anti-inflammatory effects in vivo. J Biol Chem 272: 21096-21103.
    • (1997) J Biol Chem , vol.272 , pp. 21096-21103
    • Pierce, J.W.1    Schoenleber, R.2    Jesmok, G.3    Best, J.4    Moore, S.A.5    Collins, T.6    Gerritsen, M.E.7
  • 38
    • 84867244394 scopus 로고    scopus 로고
    • Glutamine depletion and glucose depletion trigger growth inhibition via distinctive gene expression reprogramming
    • Qie S, Liang D, Yin C, Gu W, Meng M, Wang C, Sang N,. 2012. Glutamine depletion and glucose depletion trigger growth inhibition via distinctive gene expression reprogramming. Cell Cycle 11: 3679-3690.
    • (2012) Cell Cycle , vol.11 , pp. 3679-3690
    • Qie, S.1    Liang, D.2    Yin, C.3    Gu, W.4    Meng, M.5    Wang, C.6    Sang, N.7
  • 39
    • 54349098717 scopus 로고    scopus 로고
    • A combination of Trastuzumab and 17-AAG induces enhanced ubiquitinylation and lysosomal pathway-dependent ErbB2 degradation and cytotoxicity in ErbB2-overexpressing breast cancer cells
    • Raja SM, Clubb RJ, Bhattacharyya M, Dimri M, Cheng H, Pan W, Ortega-Cava C, Lakku-Reddi A, Naramura M, Band V, Band H,. 2008. A combination of Trastuzumab and 17-AAG induces enhanced ubiquitinylation and lysosomal pathway-dependent ErbB2 degradation and cytotoxicity in ErbB2-overexpressing breast cancer cells. Cancer Biol Ther 7: 1630-1640.
    • (2008) Cancer Biol Ther , vol.7 , pp. 1630-1640
    • Raja, S.M.1    Clubb, R.J.2    Bhattacharyya, M.3    Dimri, M.4    Cheng, H.5    Pan, W.6    Ortega-Cava, C.7    Lakku-Reddi, A.8    Naramura, M.9    Band, V.10    Band, H.11
  • 40
    • 77957946628 scopus 로고    scopus 로고
    • How estrogen fuels breast cancer
    • Rana A, Rangasamy V, Mishra R,. 2010. How estrogen fuels breast cancer. Future Oncol 6: 1369-1371.
    • (2010) Future Oncol , vol.6 , pp. 1369-1371
    • Rana, A.1    Rangasamy, V.2    Mishra, R.3
  • 42
    • 0018386209 scopus 로고
    • Evidence that glutamine, not sugar, is the major energy source for cultured HeLa cells
    • Reitzer LJ, Wice BM, Kennell D,. 1979. Evidence that glutamine, not sugar, is the major energy source for cultured HeLa cells. J Biol Chem 254: 2669-2676.
    • (1979) J Biol Chem , vol.254 , pp. 2669-2676
    • Reitzer, L.J.1    Wice, B.M.2    Kennell, D.3
  • 44
    • 0037515549 scopus 로고    scopus 로고
    • MAPK signaling up-regulates the activity of hypoxia-inducible factors by its effects on p300
    • Sang N, Stiehl DP, Bohensky J, Leshchinsky I, Srinivas V, Caro J,. 2003. MAPK signaling up-regulates the activity of hypoxia-inducible factors by its effects on p300. J Biol Chem 278: 14013-14019.
    • (2003) J Biol Chem , vol.278 , pp. 14013-14019
    • Sang, N.1    Stiehl, D.P.2    Bohensky, J.3    Leshchinsky, I.4    Srinivas, V.5    Caro, J.6
  • 46
    • 37049183697 scopus 로고
    • Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
    • Slamon DJ, Clark GM, Wong SG, Levin WJ, Ullrich A, McGuire WL,. 1987. Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 235: 177-182.
    • (1987) Science , vol.235 , pp. 177-182
    • Slamon, D.J.1    Clark, G.M.2    Wong, S.G.3    Levin, W.J.4    Ullrich, A.5    McGuire, W.L.6
  • 47
    • 57549118957 scopus 로고    scopus 로고
    • Focus on molecules: Nuclear factor-kappaB
    • Srivastava SK, Ramana KV,. 2009. Focus on molecules: nuclear factor-kappaB. Exp Eye Res 88: 2-3.
    • (2009) Exp Eye Res , vol.88 , pp. 2-3
    • Srivastava, S.K.1    Ramana, K.V.2
  • 49
    • 0027968054 scopus 로고
    • Glutamine modulates phenotype and stimulates proliferation in human colon cancer cell lines
    • Turowski GA, Rashid Z, Hong F, Madri JA, Basson MD,. 1994. Glutamine modulates phenotype and stimulates proliferation in human colon cancer cell lines. Cancer Res 54: 5974-5980.
    • (1994) Cancer Res , vol.54 , pp. 5974-5980
    • Turowski, G.A.1    Rashid, Z.2    Hong, F.3    Madri, J.A.4    Basson, M.D.5
  • 50
    • 66249108601 scopus 로고    scopus 로고
    • Understanding the Warburg effect: The metabolic requirements of cell proliferation
    • Vander Heiden MG, Cantley LC, Thompson CB, 2009. Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science 324: 1029-1033.
    • (2009) Science , vol.324 , pp. 1029-1033
    • Vander Heiden, M.G.1    Cantley, L.C.2    Thompson, C.B.3
  • 53
    • 84860316773 scopus 로고    scopus 로고
    • Carbon source metabolism and its regulation in cancer cells
    • Yin C, Qie S, Sang N,. 2012. Carbon source metabolism and its regulation in cancer cells. Crit Rev Eukaryot Gene Expr 22: 17-35.
    • (2012) Crit Rev Eukaryot Gene Expr , vol.22 , pp. 17-35
    • Yin, C.1    Qie, S.2    Sang, N.3
  • 54
    • 34347402459 scopus 로고    scopus 로고
    • Deficiency in glutamine but not glucose induces MYC-dependent apoptosis in human cells
    • Yuneva M, Zamboni N, Oefner P, Sachidanandam R, Lazebnik Y,. 2007. Deficiency in glutamine but not glucose induces MYC-dependent apoptosis in human cells. J Cell Biol 178: 93-105.
    • (2007) J Cell Biol , vol.178 , pp. 93-105
    • Yuneva, M.1    Zamboni, N.2    Oefner, P.3    Sachidanandam, R.4    Lazebnik, Y.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.