-
1
-
-
0035256698
-
Untangling the ErbB signalling network
-
10.1038/35052073, 11252954
-
Yarden Y, Sliwkowski MX. Untangling the ErbB signalling network. Nat Rev Mol Cell Biol 2001, 2:127-137. 10.1038/35052073, 11252954.
-
(2001)
Nat Rev Mol Cell Biol
, vol.2
, pp. 127-137
-
-
Yarden, Y.1
Sliwkowski, M.X.2
-
2
-
-
0041629450
-
Status of epidermal growth factor receptor antagonists in the biology and treatment of cancer
-
10.1200/JCO.2003.01.504, 12860957
-
Mendelsohn J, Baselga J. Status of epidermal growth factor receptor antagonists in the biology and treatment of cancer. J Clin Oncol 2003, 21:2787-2799. 10.1200/JCO.2003.01.504, 12860957.
-
(2003)
J Clin Oncol
, vol.21
, pp. 2787-2799
-
-
Mendelsohn, J.1
Baselga, J.2
-
3
-
-
4444309305
-
The EGF receptor family as therapeutic targets in breast cancer
-
Lemmon MA. The EGF receptor family as therapeutic targets in breast cancer. Breast Dis 2003, 18:33-43.
-
(2003)
Breast Dis
, vol.18
, pp. 33-43
-
-
Lemmon, M.A.1
-
4
-
-
18344390418
-
ERBB receptors and cancer: the complexity of targeted inhibitors
-
10.1038/nrc1609, 15864276
-
Hynes NE, Lane HA. ERBB receptors and cancer: the complexity of targeted inhibitors. Nat Rev Cancer 2005, 5:341-354. 10.1038/nrc1609, 15864276.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 341-354
-
-
Hynes, N.E.1
Lane, H.A.2
-
5
-
-
3042740814
-
HER2 expression in breast cancer primary tumours and corresponding metastases: original data and literature review
-
2409528, 15150568
-
Carlsson J, Nordgren H, Sjöström J, Wester K, Villman K, Bengtsson NO, Ostenstad B, Lundqvist H, Blomqvist C. HER2 expression in breast cancer primary tumours and corresponding metastases: original data and literature review. Br J Cancer 2004, 90:2344-2348. 2409528, 15150568.
-
(2004)
Br J Cancer
, vol.90
, pp. 2344-2348
-
-
Carlsson, J.1
Nordgren, H.2
Sjöström, J.3
Wester, K.4
Villman, K.5
Bengtsson, N.O.6
Ostenstad, B.7
Lundqvist, H.8
Blomqvist, C.9
-
6
-
-
37049183697
-
Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene
-
10.1126/science.3798106, 3798106
-
Slamon DJ, Clark GM, Wong SG, Levin WJ, Ullrich A, McGuire WL. Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 1987, 235:177-182. 10.1126/science.3798106, 3798106.
-
(1987)
Science
, vol.235
, pp. 177-182
-
-
Slamon, D.J.1
Clark, G.M.2
Wong, S.G.3
Levin, W.J.4
Ullrich, A.5
McGuire, W.L.6
-
7
-
-
0344333420
-
Prognostic and predictive value of c-erbB-2 overexpression in primary breast cancer, alone and in combination with other prognostic markers
-
Sjögren S, Inganãs M, Lindgren A, Holmberg L, Bergh J. Prognostic and predictive value of c-erbB-2 overexpression in primary breast cancer, alone and in combination with other prognostic markers. J Clin Oncol 1998, 16:462-469.
-
(1998)
J Clin Oncol
, vol.16
, pp. 462-469
-
-
Sjögren, S.1
Inganãs, M.2
Lindgren, A.3
Holmberg, L.4
Bergh, J.5
-
8
-
-
0037429779
-
The deaf and the dumb: the biology of ErbB-2 and ErbB-3
-
10.1016/S0014-4827(02)00101-5, 12648465
-
Citri A, Skaria KB, Yarden Y. The deaf and the dumb: the biology of ErbB-2 and ErbB-3. Exp Cell Res 2003, 284:54-65. 10.1016/S0014-4827(02)00101-5, 12648465.
-
(2003)
Exp Cell Res
, vol.284
, pp. 54-65
-
-
Citri, A.1
Skaria, K.B.2
Yarden, Y.3
-
9
-
-
0029814271
-
A hierarchical network of interreceptor interactions determines signal transduction by Neu differentiation factor/neuregulin and epidermal growth factor
-
231527, 8816440
-
Tzahar E, Waterman H, Chen X, Levkowitz G, Karunagaran D, Lavi S, Ratzkin BJ, Yarden Y. A hierarchical network of interreceptor interactions determines signal transduction by Neu differentiation factor/neuregulin and epidermal growth factor. Mol Cell Biol 1996, 16:5276-5287. 231527, 8816440.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 5276-5287
-
-
Tzahar, E.1
Waterman, H.2
Chen, X.3
Levkowitz, G.4
Karunagaran, D.5
Lavi, S.6
Ratzkin, B.J.7
Yarden, Y.8
-
10
-
-
0037931402
-
Quantitative analysis of HER2-mediated effects on HER2 and epidermal growth factor receptor endocytosis
-
10.1074/jbc.M300477200, 12686539
-
Hendriks BS, Opresko LK, Wiley HS, Lauffenburger D. Quantitative analysis of HER2-mediated effects on HER2 and epidermal growth factor receptor endocytosis. J Biol Chem 2003, 278:23343-23351. 10.1074/jbc.M300477200, 12686539.
-
(2003)
J Biol Chem
, vol.278
, pp. 23343-23351
-
-
Hendriks, B.S.1
Opresko, L.K.2
Wiley, H.S.3
Lauffenburger, D.4
-
11
-
-
0030944455
-
ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signalling
-
10.1093/emboj/16.7.1647, 1169769, 9130710
-
Graus-Porta D, Beerli RR, Daly JM, Hynes NE. ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signalling. EMBO J 1997, 16:1647-1655. 10.1093/emboj/16.7.1647, 1169769, 9130710.
-
(1997)
EMBO J
, vol.16
, pp. 1647-1655
-
-
Graus-Porta, D.1
Beerli, R.R.2
Daly, J.M.3
Hynes, N.E.4
-
12
-
-
0029912203
-
All ErbB receptors other than the epidermal growth factor receptor are endocytosis impaired
-
10.1074/jbc.271.31.18989, 8617810
-
Baulida J, Kraus MH, Alimandi M, Di Fiore PP, Carpenter G. All ErbB receptors other than the epidermal growth factor receptor are endocytosis impaired. J Biol Chem 1996, 271:5251-5257. 10.1074/jbc.271.31.18989, 8617810.
-
(1996)
J Biol Chem
, vol.271
, pp. 5251-5257
-
-
Baulida, J.1
Kraus, M.H.2
Alimandi, M.3
Di Fiore, P.P.4
Carpenter, G.5
-
13
-
-
0032526729
-
Differential endocytic routing of homo- and hetero-dimeric ErbB tyrosine kinases confers signaling superiority to receptor heterodimers
-
10.1093/emboj/17.12.3385, 1170676, 9628875
-
Lenferink AE, Pinkas-Kramarski R, Poll ML, van Vugt MJ, Klapper LN, Tzahar E, Waterman H, Sela M, van Zoelen EJ, Yarden Y. Differential endocytic routing of homo- and hetero-dimeric ErbB tyrosine kinases confers signaling superiority to receptor heterodimers. EMBO J 1998, 17:3385-3397. 10.1093/emboj/17.12.3385, 1170676, 9628875.
-
(1998)
EMBO J
, vol.17
, pp. 3385-3397
-
-
Lenferink, A.E.1
Pinkas-Kramarski, R.2
Poll, M.L.3
van Vugt, M.J.4
Klapper, L.N.5
Tzahar, E.6
Waterman, H.7
Sela, M.8
van Zoelen, E.J.9
Yarden, Y.10
-
14
-
-
0033605560
-
ErbB-2 amplification inhibits down-regulation and induces constitutive activation of both ErbB-2 and epidermal growth factor receptors
-
10.1074/jbc.274.13.8865, 10085130
-
Worthylake R, Opresko LK, Wiley HS. ErbB-2 amplification inhibits down-regulation and induces constitutive activation of both ErbB-2 and epidermal growth factor receptors. J Biol Chem 1999, 274:8865-8874. 10.1074/jbc.274.13.8865, 10085130.
-
(1999)
J Biol Chem
, vol.274
, pp. 8865-8874
-
-
Worthylake, R.1
Opresko, L.K.2
Wiley, H.S.3
-
15
-
-
0029783549
-
Neu differentiation factor/neuregulin isoforms activate distinct receptor combinations
-
10.1074/jbc.271.32.19029, 8702572
-
Pinkas-Kramarski R, Shelly M, Glathe S, Ratzkin BJ, Yarden Y. Neu differentiation factor/neuregulin isoforms activate distinct receptor combinations. J Biol Chem 1996, 271:19029-19032. 10.1074/jbc.271.32.19029, 8702572.
-
(1996)
J Biol Chem
, vol.271
, pp. 19029-19032
-
-
Pinkas-Kramarski, R.1
Shelly, M.2
Glathe, S.3
Ratzkin, B.J.4
Yarden, Y.5
-
16
-
-
0035257549
-
Rationale for trastuzumab (Herceptin) in adjuvant breast cancer trials
-
10.1016/S0093-7754(01)90188-5, 11301370
-
Slamon D, Pegram M. Rationale for trastuzumab (Herceptin) in adjuvant breast cancer trials. Semin Oncol 2001, 28:13-19. 10.1016/S0093-7754(01)90188-5, 11301370.
-
(2001)
Semin Oncol
, vol.28
, pp. 13-19
-
-
Slamon, D.1
Pegram, M.2
-
17
-
-
36048985668
-
The role of trastuzumab in early stage breast cancer: current data and treatment recommendations
-
10.1007/s11864-007-0008-2, 17660958
-
Lin A, Rugo HS. The role of trastuzumab in early stage breast cancer: current data and treatment recommendations. Curr Treat Options Oncol 2007, 8:47-60. 10.1007/s11864-007-0008-2, 17660958.
-
(2007)
Curr Treat Options Oncol
, vol.8
, pp. 47-60
-
-
Lin, A.1
Rugo, H.S.2
-
18
-
-
56949108012
-
Her2-positive breast cancer: herceptin and beyond
-
10.1016/j.ejca.2008.09.013, 19022660
-
Dean-Colomb W, Esteva FJ. Her2-positive breast cancer: herceptin and beyond. Eur J Cancer 2008, 44:2806-2812. 10.1016/j.ejca.2008.09.013, 19022660.
-
(2008)
Eur J Cancer
, vol.44
, pp. 2806-2812
-
-
Dean-Colomb, W.1
Esteva, F.J.2
-
19
-
-
53149153173
-
Do HER-2 positive metastatic breast cancer patients benefit from the use of trastuzumab beyond disease progression? A mono-institutional experience and systematic review of observational studies
-
10.1016/j.breast.2008.03.006, 18450443
-
Fabi A, Metro G, Ferretti G, Giannarelli D, Di Cosimo S, Papaldo P, Mottolese M, Carlini P, Felici A, Russillo M, Cognetti F. Do HER-2 positive metastatic breast cancer patients benefit from the use of trastuzumab beyond disease progression? A mono-institutional experience and systematic review of observational studies. Breast 2008, 17:499-505. 10.1016/j.breast.2008.03.006, 18450443.
-
(2008)
Breast
, vol.17
, pp. 499-505
-
-
Fabi, A.1
Metro, G.2
Ferretti, G.3
Giannarelli, D.4
Di Cosimo, S.5
Papaldo, P.6
Mottolese, M.7
Carlini, P.8
Felici, A.9
Russillo, M.10
Cognetti, F.11
-
20
-
-
46949109559
-
A phase II study of weekly vinorelbine and trastuzumab in patients with HER2-positive metastatic breast cancer
-
10.3816/CBC.2008.n.030, 18650157
-
Bayo-Calero JL, Mayordomo JI, Sánchez-Rovira P, Pérez-Carrión R, Illaramendi JJ, García-Bueno JM, González-Flores E, Crespo C, Ramos-Vázquez M, García-Palomo A, Ruiz-Borrego M, de la Haba J, Gómez-Bernal A, Yubero-Esteban A. A phase II study of weekly vinorelbine and trastuzumab in patients with HER2-positive metastatic breast cancer. Clin Breast Cancer 2008, 8:264-268. 10.3816/CBC.2008.n.030, 18650157.
-
(2008)
Clin Breast Cancer
, vol.8
, pp. 264-268
-
-
Bayo-Calero, J.L.1
Mayordomo, J.I.2
Sánchez-Rovira, P.3
Pérez-Carrión, R.4
Illaramendi, J.J.5
García-Bueno, J.M.6
González-Flores, E.7
Crespo, C.8
Ramos-Vázquez, M.9
García-Palomo, A.10
Ruiz-Borrego, M.11
de la Haba, J.12
Gómez-Bernal, A.13
Yubero-Esteban, A.14
-
21
-
-
46349097513
-
HER-2-positive breast cancer: current treatment strategies
-
10.1080/07357900801971024, 18584344
-
Perez EA, Baweja M. HER-2-positive breast cancer: current treatment strategies. Cancer Invest 2008, 26:545-552. 10.1080/07357900801971024, 18584344.
-
(2008)
Cancer Invest
, vol.26
, pp. 545-552
-
-
Perez, E.A.1
Baweja, M.2
-
22
-
-
49149084837
-
Phase I dose escalation and pharmacokinetic study of lapatinib in combination with trastuzumab in patients with advanced ErbB2-positive breast cancer
-
10.1200/JCO.2007.13.5202, 18490651
-
Storniolo AM, Pegram MD, Overmoyer B, Silverman P, Peacock NW, Jones SF, Loftiss J, Arya N, Koch KM, Paul E, Pandite L, Fleming RA, Lebowitz PF, Ho PT, Burris HA. Phase I dose escalation and pharmacokinetic study of lapatinib in combination with trastuzumab in patients with advanced ErbB2-positive breast cancer. J Clin Oncol 2008, 26:3317-3323. 10.1200/JCO.2007.13.5202, 18490651.
-
(2008)
J Clin Oncol
, vol.26
, pp. 3317-3323
-
-
Storniolo, A.M.1
Pegram, M.D.2
Overmoyer, B.3
Silverman, P.4
Peacock, N.W.5
Jones, S.F.6
Loftiss, J.7
Arya, N.8
Koch, K.M.9
Paul, E.10
Pandite, L.11
Fleming, R.A.12
Lebowitz, P.F.13
Ho, P.T.14
Burris, H.A.15
-
23
-
-
0037268613
-
Assessment of epidermal growth factor receptor with 99 mTc-ethylenedicysteine-C225 monoclonal antibody
-
10.1097/00001813-200301000-00007, 12544258
-
Schechter NR, Yang DJ, Azhdarinia A, Kohanim S, Wendt R, Oh CS, Hu M, Yu DF, Bryant J, Ang KK, Forster KM, Kim EE, Podoloff DA. Assessment of epidermal growth factor receptor with 99 mTc-ethylenedicysteine-C225 monoclonal antibody. Anticancer Drugs 2003, 14:49-56. 10.1097/00001813-200301000-00007, 12544258.
-
(2003)
Anticancer Drugs
, vol.14
, pp. 49-56
-
-
Schechter, N.R.1
Yang, D.J.2
Azhdarinia, A.3
Kohanim, S.4
Wendt, R.5
Oh, C.S.6
Hu, M.7
Yu, D.F.8
Bryant, J.9
Ang, K.K.10
Forster, K.M.11
Kim, E.E.12
Podoloff, D.A.13
-
24
-
-
45349098002
-
Enhanced EGFR inhibition and distinct epitope recognition by EGFR antagonistic mAbs C225 and 425
-
Kamat V, Donaldson JM, Kari C, Quadros MR, Lelkes PI, Chaiken I, Cocklin S, Williams JC, Papazoglou E, Rodeck U. Enhanced EGFR inhibition and distinct epitope recognition by EGFR antagonistic mAbs C225 and 425. Cancer Biol Ther 2008, 7:726-733.
-
(2008)
Cancer Biol Ther
, vol.7
, pp. 726-733
-
-
Kamat, V.1
Donaldson, J.M.2
Kari, C.3
Quadros, M.R.4
Lelkes, P.I.5
Chaiken, I.6
Cocklin, S.7
Williams, J.C.8
Papazoglou, E.9
Rodeck, U.10
-
25
-
-
4644289313
-
A unique structure for epidermal growth factor receptor bound to GW572016 (Lapatinib): relationships among protein conformation, inhibitor off-rate, and receptor activity in tumor cells
-
10.1158/0008-5472.CAN-04-1168, 15374980
-
Wood ER, Truesdale AT, McDonald OB, Yuan D, Hassell A, Dickerson SH, Ellis B, Pennisi C, Horne E, Lackey K, Alligood KJ, Rusnak DW, Gilmer TM, Shewchuk L. A unique structure for epidermal growth factor receptor bound to GW572016 (Lapatinib): relationships among protein conformation, inhibitor off-rate, and receptor activity in tumor cells. Cancer Res 2004, 64:6652-6659. 10.1158/0008-5472.CAN-04-1168, 15374980.
-
(2004)
Cancer Res
, vol.64
, pp. 6652-6659
-
-
Wood, E.R.1
Truesdale, A.T.2
McDonald, O.B.3
Yuan, D.4
Hassell, A.5
Dickerson, S.H.6
Ellis, B.7
Pennisi, C.8
Horne, E.9
Lackey, K.10
Alligood, K.J.11
Rusnak, D.W.12
Gilmer, T.M.13
Shewchuk, L.14
-
26
-
-
38049025794
-
Review: side effects of approved molecular targeted therapies in solid cancers
-
10.1634/theoncologist.12-12-1443, 18165622
-
Widakowich C, De Castro G, De Azambuja E, Dinh P, Awada A. Review: side effects of approved molecular targeted therapies in solid cancers. The Oncologist 2007, 12:1443-1455. 10.1634/theoncologist.12-12-1443, 18165622.
-
(2007)
The Oncologist
, vol.12
, pp. 1443-1455
-
-
Widakowich, C.1
De Castro, G.2
De Azambuja, E.3
Dinh, P.4
Awada, A.5
-
27
-
-
44049100934
-
Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy
-
10.1093/jnci/djn123, 18445819
-
Li X, Lewis MT, Huang J, Gutierrez C, Osborne CK, Wu MF, Hilsenbeck SG, Pavlick A, Zhang X, Chamness GC, Wong H, Rosen J, Chang JC. Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy. J Natl Cancer Inst 2008, 100:672-679. 10.1093/jnci/djn123, 18445819.
-
(2008)
J Natl Cancer Inst
, vol.100
, pp. 672-679
-
-
Li, X.1
Lewis, M.T.2
Huang, J.3
Gutierrez, C.4
Osborne, C.K.5
Wu, M.F.6
Hilsenbeck, S.G.7
Pavlick, A.8
Zhang, X.9
Chamness, G.C.10
Wong, H.11
Rosen, J.12
Chang, J.C.13
-
28
-
-
58149381635
-
A pan-HER approach for cancer therapy: background, current status and future development
-
10.1517/14712590802630427, 19063696
-
Huang Z, Brdlik C, Jin P, Shepard HM. A pan-HER approach for cancer therapy: background, current status and future development. Expert Opin Biol Ther 2009, 9:97-110. 10.1517/14712590802630427, 19063696.
-
(2009)
Expert Opin Biol Ther
, vol.9
, pp. 97-110
-
-
Huang, Z.1
Brdlik, C.2
Jin, P.3
Shepard, H.M.4
-
29
-
-
54349098717
-
A combination of trastuzumab and 17-AAG induces enhanced ubiquitinylation and lysosomal pathway-dependent ErbB2 degradation and cytotoxicity in ErbB2-overexpressing breast cancer cells
-
10.1158/1535-7163.MCT-07-2409, 2727620, 18769124
-
Raja SM, Clubb RJ, Bhattacharyya M, Dimri M, Cheng H, Pan W, Ortega-Cava C, Lakku-Reddi A, Naramura M, Band V, Band H. A combination of trastuzumab and 17-AAG induces enhanced ubiquitinylation and lysosomal pathway-dependent ErbB2 degradation and cytotoxicity in ErbB2-overexpressing breast cancer cells. Cancer Biol Ther 2008, 7:1630-1640. 10.1158/1535-7163.MCT-07-2409, 2727620, 18769124.
-
(2008)
Cancer Biol Ther
, vol.7
, pp. 1630-1640
-
-
Raja, S.M.1
Clubb, R.J.2
Bhattacharyya, M.3
Dimri, M.4
Cheng, H.5
Pan, W.6
Ortega-Cava, C.7
Lakku-Reddi, A.8
Naramura, M.9
Band, V.10
Band, H.11
-
30
-
-
3543041878
-
Defective downregulation of receptor tyrosine kinases in cancer
-
10.1038/sj.emboj.7600292, 514952, 15229652
-
Bache KG, Salgsvold T, Stenmark H. Defective downregulation of receptor tyrosine kinases in cancer. EMBO J 2004, 23:2707-2712. 10.1038/sj.emboj.7600292, 514952, 15229652.
-
(2004)
EMBO J
, vol.23
, pp. 2707-2712
-
-
Bache, K.G.1
Salgsvold, T.2
Stenmark, H.3
-
31
-
-
58149232649
-
Unraveling the biologic and clinical complexities of HER2
-
10.3816/CBC.2008.n.047, 18952552
-
Park JW, Neve RM, Szollosi J, Benz CC. Unraveling the biologic and clinical complexities of HER2. Clin Breast Cancer 2008, 8:392-401. 10.3816/CBC.2008.n.047, 18952552.
-
(2008)
Clin Breast Cancer
, vol.8
, pp. 392-401
-
-
Park, J.W.1
Neve, R.M.2
Szollosi, J.3
Benz, C.C.4
-
32
-
-
34548152541
-
Trastuzumab-related cardiotoxicity: calling into question the concept of reversibility
-
10.1200/JCO.2007.11.0106, 17687157
-
Telli ML, Hunt SA, Carlson RW, Guardino AE. Trastuzumab-related cardiotoxicity: calling into question the concept of reversibility. J Clin Oncol 2007, 25:3525-3533. 10.1200/JCO.2007.11.0106, 17687157.
-
(2007)
J Clin Oncol
, vol.25
, pp. 3525-3533
-
-
Telli, M.L.1
Hunt, S.A.2
Carlson, R.W.3
Guardino, A.E.4
-
33
-
-
38449115081
-
Overview of resistance to systemic therapy in patients with breast cancer
-
full_text, 17993229
-
Gonzalez-Angulo AM, Morales-Vasquez F, Hortobagyi GN. Overview of resistance to systemic therapy in patients with breast cancer. Adv Exp Med Biol 2007, 608:1-22. full_text, 17993229.
-
(2007)
Adv Exp Med Biol
, vol.608
, pp. 1-22
-
-
Gonzalez-Angulo, A.M.1
Morales-Vasquez, F.2
Hortobagyi, G.N.3
-
34
-
-
0026922513
-
Studies of human tumors by MRS: a review
-
Negendank WG. Studies of human tumors by MRS: a review. NMR Biomed 1992, 5:303-324.
-
(1992)
NMR Biomed
, vol.5
, pp. 303-324
-
-
Negendank, W.G.1
-
35
-
-
0033371680
-
Tumour phospholipid metabolism
-
10.1002/(SICI)1099-1492(199911)12:7<413::AID-NBM587>3.0.CO;2-U, 10654290
-
Podo F. Tumour phospholipid metabolism. NMR Biomed 1999, 12:413-439. 10.1002/(SICI)1099-1492(199911)12:7<413::AID-NBM587>3.0.CO;2-U, 10654290.
-
(1999)
NMR Biomed
, vol.12
, pp. 413-439
-
-
Podo, F.1
-
36
-
-
27144444683
-
Alterations of choline phospholipid metabolism in ovarian tumor progression
-
10.1158/0008-5472.CAN-05-1146, 16230400
-
Iorio E, Mezzanzanica D, Alberti P, Spadaro F, Ramoni C, D'Ascenzo S, Millimaggi D, Pavan A, Dolo V, Canevari S, Podo F. Alterations of choline phospholipid metabolism in ovarian tumor progression. Cancer Res 2005, 65:9369-9376. 10.1158/0008-5472.CAN-05-1146, 16230400.
-
(2005)
Cancer Res
, vol.65
, pp. 9369-9376
-
-
Iorio, E.1
Mezzanzanica, D.2
Alberti, P.3
Spadaro, F.4
Ramoni, C.5
D'Ascenzo, S.6
Millimaggi, D.7
Pavan, A.8
Dolo, V.9
Canevari, S.10
Podo, F.11
-
37
-
-
33750383279
-
Choline phospholipid metabolism in cancer: consequences for molecular pharmaceutical interventions
-
10.1021/mp060067e, 17009848
-
Glunde K, Ackerstaff E, Mori N, Jacobs MA, Bhujwalla ZM. Choline phospholipid metabolism in cancer: consequences for molecular pharmaceutical interventions. Mol Pharm 2006, 3:496-506. 10.1021/mp060067e, 17009848.
-
(2006)
Mol Pharm
, vol.3
, pp. 496-506
-
-
Glunde, K.1
Ackerstaff, E.2
Mori, N.3
Jacobs, M.A.4
Bhujwalla, Z.M.5
-
38
-
-
34248681296
-
Abnormal choline phospholipid metabolism in breast and ovary cancer: molecular bases for noninvasive imaging approaches
-
Podo F, Sardanelli F, Iorio E, Canese R, Carpinelli G, Fausto A, Canevari S. Abnormal choline phospholipid metabolism in breast and ovary cancer: molecular bases for noninvasive imaging approaches. Curr Mol Imaging Rev 2007, 3:123-137.
-
(2007)
Curr Mol Imaging Rev
, vol.3
, pp. 123-137
-
-
Podo, F.1
Sardanelli, F.2
Iorio, E.3
Canese, R.4
Carpinelli, G.5
Fausto, A.6
Canevari, S.7
-
39
-
-
4444370177
-
Phosphatidylcholine-specific phospholipase C in mitogen-stimulated fibroblasts
-
10.1016/j.yexcr.2004.05.037, 15350536
-
Ramoni C, Spadaro F, Barletta B, Dupuis ML, Podo F. Phosphatidylcholine-specific phospholipase C in mitogen-stimulated fibroblasts. Exp Cell Res 2004, 299:370-372. 10.1016/j.yexcr.2004.05.037, 15350536.
-
(2004)
Exp Cell Res
, vol.299
, pp. 370-372
-
-
Ramoni, C.1
Spadaro, F.2
Barletta, B.3
Dupuis, M.L.4
Podo, F.5
-
40
-
-
35348873163
-
Functional role of phosphatidylcholine-specific phospholipase C in regulating CD16 membrane expression in natural killer cells
-
10.1002/eji.200737266, 17899539
-
Cecchetti S, Spadaro F, Lugini L, Podo F, Ramoni C. Functional role of phosphatidylcholine-specific phospholipase C in regulating CD16 membrane expression in natural killer cells. Eur J Immunol 2007, 37:2912-2922. 10.1002/eji.200737266, 17899539.
-
(2007)
Eur J Immunol
, vol.37
, pp. 2912-2922
-
-
Cecchetti, S.1
Spadaro, F.2
Lugini, L.3
Podo, F.4
Ramoni, C.5
-
41
-
-
53049095070
-
Phosphatidylcholine-specific phospholipase C activation in epithelial ovarian cancer cells
-
10.1158/0008-5472.CAN-07-6763, 18701477
-
Spadaro F, Ramoni C, Mezzanzanica D, Miotti S, Alberti P, Cecchetti S, Iorio E, Dolo V, Canevari S, Podo F. Phosphatidylcholine-specific phospholipase C activation in epithelial ovarian cancer cells. Cancer Res 2008, 68:6541-6549. 10.1158/0008-5472.CAN-07-6763, 18701477.
-
(2008)
Cancer Res
, vol.68
, pp. 6541-6549
-
-
Spadaro, F.1
Ramoni, C.2
Mezzanzanica, D.3
Miotti, S.4
Alberti, P.5
Cecchetti, S.6
Iorio, E.7
Dolo, V.8
Canevari, S.9
Podo, F.10
-
42
-
-
0023050503
-
Antibodies prepared to Bacillus cereus phospholipases C cross react with a phosphatidylcholine preferring phospholipases C in mammalian cells
-
10.1016/0006-291X(86)91065-X, 3096314
-
Clark MA, Shorr RG, Bomalaski JS. Antibodies prepared to Bacillus cereus phospholipases C cross react with a phosphatidylcholine preferring phospholipases C in mammalian cells. Biochem Biophys Res Commun 1986, 140:114-119. 10.1016/0006-291X(86)91065-X, 3096314.
-
(1986)
Biochem Biophys Res Commun
, vol.140
, pp. 114-119
-
-
Clark, M.A.1
Shorr, R.G.2
Bomalaski, J.S.3
-
43
-
-
0030018131
-
Detection of phosphatidylcholine-specific phospholipase C in NIH-3T3 fibroblasts and their H-ras transformants: NMR and immunochemical studies
-
Podo F, Ferretti A, Knijn A, Zhang P, Ramoni C, Barletta B, Pini C, Baccarini S, Pulciani S. Detection of phosphatidylcholine-specific phospholipase C in NIH-3T3 fibroblasts and their H-ras transformants: NMR and immunochemical studies. Anticancer Res 1996, 16:1399-1412.
-
(1996)
Anticancer Res
, vol.16
, pp. 1399-1412
-
-
Podo, F.1
Ferretti, A.2
Knijn, A.3
Zhang, P.4
Ramoni, C.5
Barletta, B.6
Pini, C.7
Baccarini, S.8
Pulciani, S.9
-
44
-
-
0035451096
-
Cellular localization and functional role of phosphatidylcholine-specific phospholipase C in NK cells
-
Ramoni C, Spadaro F, Menegon M, Podo F. Cellular localization and functional role of phosphatidylcholine-specific phospholipase C in NK cells. J Immunol 2001, 167:2642-2650.
-
(2001)
J Immunol
, vol.167
, pp. 2642-2650
-
-
Ramoni, C.1
Spadaro, F.2
Menegon, M.3
Podo, F.4
-
45
-
-
0021061819
-
Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays
-
10.1016/0022-1759(83)90303-4, 6606682
-
Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 1983, 65:55-63. 10.1016/0022-1759(83)90303-4, 6606682.
-
(1983)
J Immunol Methods
, vol.65
, pp. 55-63
-
-
Mosmann, T.1
-
46
-
-
0025367455
-
Comparison of in vitro anticancer-drug-screening data generated with a tetrazolium assay versus a protein assay against a diverse panel of human tumor cell lines
-
10.1093/jnci/82.13.1113, 2359137
-
Rubinstein LV, Shoemaker RH, Paull KD, Simm RM, Tosini S, Skehan P, Scadiero DA, Momks A, Boyd MR. Comparison of in vitro anticancer-drug-screening data generated with a tetrazolium assay versus a protein assay against a diverse panel of human tumor cell lines. J Natl Cancer Inst 1990, 82:1113-1120. 10.1093/jnci/82.13.1113, 2359137.
-
(1990)
J Natl Cancer Inst
, vol.82
, pp. 1113-1120
-
-
Rubinstein, L.V.1
Shoemaker, R.H.2
Paull, K.D.3
Simm, R.M.4
Tosini, S.5
Skehan, P.6
Scadiero, D.A.7
Momks, A.8
Boyd, M.R.9
-
47
-
-
33845576210
-
Expression and role of phosphatidylcholine-specific phospholipase C in human NK and T-lymphocyte subsets
-
10.1002/eji.200635927, 17111345
-
Spadaro F, Cecchetti S, Sanchez M, Ausiello CM, Podo F, Ramoni C. Expression and role of phosphatidylcholine-specific phospholipase C in human NK and T-lymphocyte subsets. Eur J Immunol 2006, 36:3277-3287. 10.1002/eji.200635927, 17111345.
-
(2006)
Eur J Immunol
, vol.36
, pp. 3277-3287
-
-
Spadaro, F.1
Cecchetti, S.2
Sanchez, M.3
Ausiello, C.M.4
Podo, F.5
Ramoni, C.6
-
48
-
-
0027275642
-
Signal transducing molecules and glycosyl-phosphatidylinositol-linked proteins form a caveolin-rich insoluble complex in MDCK cells
-
10.1083/jcb.122.4.789, 2119592, 8349730
-
Sargiacomo M, Sudol M, Tang Z, Lisanti MP. Signal transducing molecules and glycosyl-phosphatidylinositol-linked proteins form a caveolin-rich insoluble complex in MDCK cells. J Cell Biol 1993, 122:789-807. 10.1083/jcb.122.4.789, 2119592, 8349730.
-
(1993)
J Cell Biol
, vol.122
, pp. 789-807
-
-
Sargiacomo, M.1
Sudol, M.2
Tang, Z.3
Lisanti, M.P.4
-
49
-
-
42549107827
-
Controlled internalization of Her-2/neu receptors by cross-linking for targeted delivery
-
10.4161/cbt.6.12.4979, 18075296
-
Zhu W, Okollie B, Artemov D. Controlled internalization of Her-2/neu receptors by cross-linking for targeted delivery. Cancer Biol Ther 2007, 6:1960-1966. 10.4161/cbt.6.12.4979, 18075296.
-
(2007)
Cancer Biol Ther
, vol.6
, pp. 1960-1966
-
-
Zhu, W.1
Okollie, B.2
Artemov, D.3
-
50
-
-
0028912598
-
Suppression and promotion of tumor growth by monoclonal antibodies to ErbB-2 differentially correlate with cellular uptake
-
10.1073/pnas.92.8.3353, 42164, 7724565
-
Hurwitz E, Stancovski I, Sela M, Yarden Y. Suppression and promotion of tumor growth by monoclonal antibodies to ErbB-2 differentially correlate with cellular uptake. Proc Natl Acad Sci USA 1995, 92:3353-3357. 10.1073/pnas.92.8.3353, 42164, 7724565.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 3353-3357
-
-
Hurwitz, E.1
Stancovski, I.2
Sela, M.3
Yarden, Y.4
-
51
-
-
22244453690
-
Herceptin-induced inhibition of ErbB2 signaling involves reduced phosphorylation of Akt but not endocytic down-regulation of ErbB2
-
10.1002/ijc.21015, 15800944
-
Longva KE, Pedersen NM, Haslekas C, Stang E, Madshus IH. Herceptin-induced inhibition of ErbB2 signaling involves reduced phosphorylation of Akt but not endocytic down-regulation of ErbB2. Int J Cancer 2005, 116:359-367. 10.1002/ijc.21015, 15800944.
-
(2005)
Int J Cancer
, vol.116
, pp. 359-367
-
-
Longva, K.E.1
Pedersen, N.M.2
Haslekas, C.3
Stang, E.4
Madshus, I.H.5
-
52
-
-
35848945726
-
ERBB2 phosphorylation and trastuzumab sensitivity of breast cancer cell lines
-
10.1038/sj.onc.1210528, 17525746
-
Ginester C, Adélaïde J, Gonçalves A, Repellini L, Sircoulomb F, Letessier A, Finetti P, Geneix J, Charafe-Jauffret E, Bertuci F, Jacquemier J, Viens P, Birnbaum D. ERBB2 phosphorylation and trastuzumab sensitivity of breast cancer cell lines. Oncogene 2007, 26:7163-7169. 10.1038/sj.onc.1210528, 17525746.
-
(2007)
Oncogene
, vol.26
, pp. 7163-7169
-
-
Ginester, C.1
Adélaïde, J.2
Gonçalves, A.3
Repellini, L.4
Sircoulomb, F.5
Letessier, A.6
Finetti, P.7
Geneix, J.8
Charafe-Jauffret, E.9
Bertuci, F.10
Jacquemier, J.11
Viens, P.12
Birnbaum, D.13
-
53
-
-
0028790239
-
Multiple pathways originate at the Fas/APO-1 (CD95) receptor: sequential involvement of phosphatidylcholine-specific phospholipase C and acidic sphingomyelinase in the propagation of the apoptotic signal
-
394704, 8846779
-
Cifone MG, Roncaioli P, De Maria R, Camarda G, Santoni A, Ruberti G, Testi R. Multiple pathways originate at the Fas/APO-1 (CD95) receptor: sequential involvement of phosphatidylcholine-specific phospholipase C and acidic sphingomyelinase in the propagation of the apoptotic signal. EMBO J 1995, 14:5859-5868. 394704, 8846779.
-
(1995)
EMBO J
, vol.14
, pp. 5859-5868
-
-
Cifone, M.G.1
Roncaioli, P.2
De Maria, R.3
Camarda, G.4
Santoni, A.5
Ruberti, G.6
Testi, R.7
-
54
-
-
33746330432
-
Contrasting effects of phosphatidylcholine-specific phospholipase C on apoptosis in cultured endothelial cells
-
10.1080/10623320600760423, 16840176
-
Liu X, Zhao Q, Araki S, Zhang S, Miao J. Contrasting effects of phosphatidylcholine-specific phospholipase C on apoptosis in cultured endothelial cells. Endothelium 2006, 13:205-211. 10.1080/10623320600760423, 16840176.
-
(2006)
Endothelium
, vol.13
, pp. 205-211
-
-
Liu, X.1
Zhao, Q.2
Araki, S.3
Zhang, S.4
Miao, J.5
-
55
-
-
34948852322
-
Phosphatidylcholine-specific phospholipase C and ROS were involved in chicken blastodisc differentiation to vascular endothelial cell
-
10.1002/jcb.21301, 17393430
-
Zhao J, Zhao B, Wang W, Huang B, Zhang S, Miao J. Phosphatidylcholine-specific phospholipase C and ROS were involved in chicken blastodisc differentiation to vascular endothelial cell. J Cell Biochem 2007, 102:421-428. 10.1002/jcb.21301, 17393430.
-
(2007)
J Cell Biochem
, vol.102
, pp. 421-428
-
-
Zhao, J.1
Zhao, B.2
Wang, W.3
Huang, B.4
Zhang, S.5
Miao, J.6
-
56
-
-
34047146388
-
Suppressing phosphatidylcholine-specific phospholipase C and elevating ROS level, NADPH oxidase activity and Rb level induced neuronal differentiation in mesenchymal stem cells
-
10.1002/jcb.21139, 17211851
-
Wang N, Xie K, Huo S, Zhao J, Zhang S, Miao J. Suppressing phosphatidylcholine-specific phospholipase C and elevating ROS level, NADPH oxidase activity and Rb level induced neuronal differentiation in mesenchymal stem cells. J Cell Biochem 2007, 100:1548-1557. 10.1002/jcb.21139, 17211851.
-
(2007)
J Cell Biochem
, vol.100
, pp. 1548-1557
-
-
Wang, N.1
Xie, K.2
Huo, S.3
Zhao, J.4
Zhang, S.5
Miao, J.6
-
57
-
-
3042562283
-
Molecular causes of the aberrant choline phospholipid metabolism in breast cancer
-
10.1158/0008-5472.CAN-03-3829, 15205341
-
Glunde K, Jie C, Bhujwalla ZM. Molecular causes of the aberrant choline phospholipid metabolism in breast cancer. Cancer Res 2004, 64:4270-4276. 10.1158/0008-5472.CAN-03-3829, 15205341.
-
(2004)
Cancer Res
, vol.64
, pp. 4270-4276
-
-
Glunde, K.1
Jie, C.2
Bhujwalla, Z.M.3
-
58
-
-
0034234854
-
Tumor-inhibitory antibodies to HER-2/ErbB-2 may act by recruiting c-cbl and enhancing ubiquitinylation of HER2
-
Kappler LN, Waterman H, Sela M, Yarden Y. Tumor-inhibitory antibodies to HER-2/ErbB-2 may act by recruiting c-cbl and enhancing ubiquitinylation of HER2. Cancer Res 2000, 60:3384-3388.
-
(2000)
Cancer Res
, vol.60
, pp. 3384-3388
-
-
Kappler, L.N.1
Waterman, H.2
Sela, M.3
Yarden, Y.4
-
59
-
-
0028148050
-
Intracellular expression of single-chain antibodies reverts ErbB-2 transformation
-
Beerli RR, Wels W, Hynes NE. Intracellular expression of single-chain antibodies reverts ErbB-2 transformation. J Biol Chem 1994, 269:23931-23936.
-
(1994)
J Biol Chem
, vol.269
, pp. 23931-23936
-
-
Beerli, R.R.1
Wels, W.2
Hynes, N.E.3
-
60
-
-
0028893444
-
Single-chain antibody mediated intracellular retention of ErbB-2 impairs neu differentiation factor and epidermal growth factor signalling
-
230341, 7532277
-
Graus-Porta D, Beerli RR, Hynes NE. Single-chain antibody mediated intracellular retention of ErbB-2 impairs neu differentiation factor and epidermal growth factor signalling. Mol Cell Biol 1995, 15:1182-1191. 230341, 7532277.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 1182-1191
-
-
Graus-Porta, D.1
Beerli, R.R.2
Hynes, N.E.3
-
61
-
-
22844439340
-
HER2-targeting antibodies modulate the cyclin-dependent kinase inhibitor p27Kip1 via multiple signaling pathways
-
Le XF, Pruefer F, Bast RC. HER2-targeting antibodies modulate the cyclin-dependent kinase inhibitor p27Kip1 via multiple signaling pathways. Cell Cycle 2005, 4:87-95.
-
(2005)
Cell Cycle
, vol.4
, pp. 87-95
-
-
Le, X.F.1
Pruefer, F.2
Bast, R.C.3
-
62
-
-
0033604449
-
Dual G1 and G2/M phase inhibition by SC-ααδ9, a combinatorially derived Cdc25 phosphatase inhibitor
-
10.1038/sj.onc.1203179, 10597298
-
Tamura K, Rice RL, Wipf P, Lazo JS. Dual G1 and G2/M phase inhibition by SC-ααδ9, a combinatorially derived Cdc25 phosphatase inhibitor. Oncogene 1999, 18:6989-6996. 10.1038/sj.onc.1203179, 10597298.
-
(1999)
Oncogene
, vol.18
, pp. 6989-6996
-
-
Tamura, K.1
Rice, R.L.2
Wipf, P.3
Lazo, J.S.4
-
63
-
-
0036725526
-
The antisignaling agent SC-ααδ9,4-(benzy-(2-[(2,5-diphenyloxazole-4-carbonyl)amino]ethyl)carbamoyl-2-decanoylaminobutyric acid, is a structurally unique phospholipid analogue with phospholipase C inhibitory activity
-
Vogt A, Pestell KE, Day BW, Lazo JS, Wipf P. The antisignaling agent SC-ααδ9,4-(benzy-(2-[(2,5-diphenyloxazole-4-carbonyl)amino]ethyl)carbamoyl-2-decanoylaminobutyric acid, is a structurally unique phospholipid analogue with phospholipase C inhibitory activity. Mol Cancer Ther 2002, 1:885-892.
-
(2002)
Mol Cancer Ther
, vol.1
, pp. 885-892
-
-
Vogt, A.1
Pestell, K.E.2
Day, B.W.3
Lazo, J.S.4
Wipf, P.5
-
64
-
-
0141454973
-
Design, synthesis, and evaluation of water-soluble phospholipid analogues as inhibitors of phospholipase C from Bacillus cereus
-
10.1021/jo034411k, 12968879
-
Franklin CL, Li H, Martin SF. Design, synthesis, and evaluation of water-soluble phospholipid analogues as inhibitors of phospholipase C from Bacillus cereus. J Org Chem 2003, 68:7298-7307. 10.1021/jo034411k, 12968879.
-
(2003)
J Org Chem
, vol.68
, pp. 7298-7307
-
-
Franklin, C.L.1
Li, H.2
Martin, S.F.3
-
65
-
-
0036236938
-
Synthesis and phospholipase C inhibitory activity of D609 diastereomers
-
10.1007/s1145-002-0908-0, 12030321
-
Gonzalez-Roura A, Casas J, Llebaria A. Synthesis and phospholipase C inhibitory activity of D609 diastereomers. Lipids 2002, 37:401-406. 10.1007/s1145-002-0908-0, 12030321.
-
(2002)
Lipids
, vol.37
, pp. 401-406
-
-
Gonzalez-Roura, A.1
Casas, J.2
Llebaria, A.3
-
66
-
-
0023749089
-
Interruption of growth signal transduction by an antiviral and antitumoral xanthate compound
-
10.1016/0014-4827(88)90463-6, 2839351
-
Müller-Decker K, Doppler C, Amtmann E, Sauer G. Interruption of growth signal transduction by an antiviral and antitumoral xanthate compound. Exp Cell Res 1988, 177:295-302. 10.1016/0014-4827(88)90463-6, 2839351.
-
(1988)
Exp Cell Res
, vol.177
, pp. 295-302
-
-
Müller-Decker, K.1
Doppler, C.2
Amtmann, E.3
Sauer, G.4
-
67
-
-
0024327349
-
Interruption of TPA-induced signals by an antiviral and antitumoral xanthate compound: inhibition of a phospholipase C type reaction
-
10.1016/0006-291X(89)91981-5, 2751648
-
Müller-Decker K. Interruption of TPA-induced signals by an antiviral and antitumoral xanthate compound: inhibition of a phospholipase C type reaction. Biochem Biophys Res Commun 1989, 162:198-205. 10.1016/0006-291X(89)91981-5, 2751648.
-
(1989)
Biochem Biophys Res Commun
, vol.162
, pp. 198-205
-
-
Müller-Decker, K.1
-
68
-
-
0025335002
-
Tumor necrosis factor induces necrosis of human carcinoma xenografts in the presence of tricyclodecan-9-yl-xanthogenate and lauric acid
-
10.1002/ijc.2910450621, 2141005
-
Amtmann E, Sauer G. Tumor necrosis factor induces necrosis of human carcinoma xenografts in the presence of tricyclodecan-9-yl-xanthogenate and lauric acid. Int J Cancer 1990, 45:1113-1118. 10.1002/ijc.2910450621, 2141005.
-
(1990)
Int J Cancer
, vol.45
, pp. 1113-1118
-
-
Amtmann, E.1
Sauer, G.2
-
69
-
-
0025172671
-
Systemic treatment of a human epidermoid non-small cell lung carcinoma xenograft with a xanthate compound causes extensive intratumoral necrosis
-
10.1016/0304-3835(90)90200-H, 2170004
-
Sauer G, Amtmann E, Hofmann W. Systemic treatment of a human epidermoid non-small cell lung carcinoma xenograft with a xanthate compound causes extensive intratumoral necrosis. Cancer Letters 1990, 53:97-102. 10.1016/0304-3835(90)90200-H, 2170004.
-
(1990)
Cancer Letters
, vol.53
, pp. 97-102
-
-
Sauer, G.1
Amtmann, E.2
Hofmann, W.3
-
70
-
-
0030480576
-
The antiviral, antitumoral xanthate D609 is a competitive inhibitor of phosphatidylcholine-specific phospholipase C
-
Amtmann E. The antiviral, antitumoral xanthate D609 is a competitive inhibitor of phosphatidylcholine-specific phospholipase C. Drugs Exp Clin Res 1996, 22:287-294.
-
(1996)
Drugs Exp Clin Res
, vol.22
, pp. 287-294
-
-
Amtmann, E.1
|