Down-regulation of glutaminase C in human hepatocarcinoma cell by diphenylarsinic acid, a degradation product of chemical warfare agents

Toxicology and Applied Pharmacology

Volumn 220, Issue 3, 2007, Pages 262-270

  Kita, Kayoko ^a   Suzuki, Toshihide ^a   Ochi, Takafumi ^a  

^a TEIKYO UNIVERSITY   (Japan)

Author keywords

Diphenylarsinic acid (DPAA); Glutaminase C (GAC); Phosphate activated glutaminase (PAG); Two dimensional electrophoresis (2 DE)

Indexed keywords

ALDEHYDE DEHYDROGENASE; ARSENIC TRIOXIDE; ARSINIC ACID DERIVATIVE; CHAPERONIN; CHEMICAL WARFARE AGENT; DIMETHYLARSINOUS ACID; DIPHENYLARSINIC ACID; GLUTAMIC ACID; GLUTAMINASE; GLUTAMINASE C; RIBOSOME PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; INTOXICATION; LIVER CELL CARCINOMA; PROTEIN EXPRESSION; TWO DIMENSIONAL ELECTROPHORESIS; UPREGULATION;

ALDEHYDE DEHYDROGENASE; ARSENICALS; ARSENITES; CACODYLIC ACID; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CHAPERONINS; CHEMICAL WARFARE AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; FLUORESCENT ANTIBODY TECHNIQUE; GLUTAMINASE; HELA CELLS; HUMANS; IMMUNOBLOTTING; ISOENZYMES; RIBOSOMAL PROTEINS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TIME FACTORS;

EID: 34247225990     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2007.01.009     Document Type: Article

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