Total isoflavones from soybean and tempeh reversed scopolamine-induced amnesia, improved cholinergic activities and reduced neuroinflammation in brain

Food and Chemical Toxicology

Volumn 65, Issue , 2014, Pages 120-128

  Ahmad, Aliya ^a   Ramasamy, Kalavathy ^a   Jaafar, Siti Murnirah ^a   Majeed, Abu Bakar Abdul ^a   Mani, Vasudevan ^a  

^a UNIVERSITI TEKNOLOGI MARA   (Malaysia)

Author keywords

Acetylcholine; Acetylcholinesterase; Memory; Neuroinflammation; Scopolamine; Tempeh

Indexed keywords

ACETYLCHOLINE; ACETYLCHOLINESTERASE; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; INTERLEUKIN 10; INTERLEUKIN 1BETA; ISOFLAVONE; PIRACETAM; SCOPOLAMINE; ISOFLAVONE DERIVATIVE;

ACETYLCHOLINE BRAIN LEVEL; ACETYLCHOLINESTERASE BRAIN LEVEL; AMNESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN LEVEL; CHOLINERGIC TRANSMISSION; CONTROLLED STUDY; DIET THERAPY; DRUG MECHANISM; ELEVATED PLUS MAZE TEST; ENZYME ACTIVITY; FERMENTED PRODUCT; MALE; NERVOUS SYSTEM INFLAMMATION; NEUROPROTECTION; NONHUMAN; PROTEIN BLOOD LEVEL; RADIAL ARM MAZE TEST; RAT; SOYBEAN; SPATIAL MEMORY; TEMPEH; WORKING MEMORY; CHOLINERGIC ACTIVITY; COMPARATIVE EFFECTIVENESS; CYTOKINE PRODUCTION; ENZYME BLOOD LEVEL; MEMORY CONSOLIDATION; REFERENCE MEMORY; SHORT TERM MEMORY;

GLYCINE MAX;

ACETYLCHOLINE; ACETYLCHOLINESTERASE; MEMORY; NEUROINFLAMMATION; SCOPOLAMINE; TEMPEH;

ACETYLCHOLINE; ACETYLCHOLINESTERASE; AMNESIA; ANIMALS; CYCLOOXYGENASE INHIBITORS; ENCEPHALITIS; ISOFLAVONES; MALE; MAZE LEARNING; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CHOLINERGIC; SCOPOLAMINE HYDROBROMIDE; SOYBEANS;

EID: 84892550627     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2013.12.025     Document Type: Article

References (42)

1. Aid S., Bosetti F. Targetingcyclooxygenases-1and -2in neuroinflammation: therapeutic implications. Biochimie 2011, 93:46-51.
2. Akiyama H., Barger S., Barnum S., Bradt B., Bauer J., Cole G.M., et al. Inflammation and Alzheimer's disease. Neurobiol. Aging 2000, 21:383-421.
3. Bagheri M., Joghataei M.T., Mohseni S., Roghani M. Genistein ameliorates learning and memory deficits in amyloid β(1-40) rat model of Alzheimer's disease. Neurobiol. Learn. Mem. 2011, 95:270-276.
4. Castro S.B., Junior C.O., Alves C.C., Dias A.T., Alves L.L., Mazzoccoli L., et al. Immunomodulatory effects and improved prognosis of experimental autoimmune encephalomyelitis after O-tetradecanoyl-genisteintreatment. Int. Immunopharmacol. 2012, 12:465-470.
5. Chang C.T., Hsu C.K., Chou S.T., Chen Y.C., Huang F.S., Chung Y.C. Effect of fermentation time on the antioxidant activities of tempeh prepared from fermented soybean using Rhizopus oligosporus. Int. J. Food Sci. Technol. 2009, 44:799-806.
6. Danciu C., Soica C., Csanyi E., Ambrus R., Feflea S., Peev C., et al. Changes in the anti-inflammatory activity of soy isoflavonoid genistein versus genistein incorporated in two types of cyclodextrin derivatives. Chem. Cent. J. 2012, 6:58.
7. De Paula M.L., Rodrigues D.H., Teixeira H.C., Barsante M.M., Souza M.A., Ferreira A.P. Genistein down-modulates pro-inflammatory cytokines and reverses clinical signs of experimental autoimmune encephalomyelitis. Int. Immunopharmacol. 2008, 8:1291-1297.
8. Devi M.K.A., Gondi M., Sakthivelu G., Giridhar P., Rajasekaran T., Ravishankar G.A. Functional attributes of soybean seeds and products, with reference to isoflavone content and antioxidant activity. Food Chem. 2009, 114:771-776.
9. Ding B.J., Ma W.W., He L.L., Zhou X., Yuan L.H., Yu H.L., et al. Soybean isoflavone alleviates β-amyloid 1-42 induced inflammatory response to improve learning and memory ability by down regulation of Toll-like receptor 4 expression and nuclear factor-κB activity in rats. Int. J. Dev. Neurosci. 2011, 29:537-542.
10. Ecobichon D.J. The Basis of Toxicity Testing 1997, CRC Press. second ed.
11. Foyet H.S., Hritcu L., Ciobica A., Stefan M., Kamtchouing P., Cojocaru D. Methanolic extract of Hibiscus asper leaves improves spatial memory deficits in the 6-hydroxydopamine-lesion rodent model of Parkinson's disease. J. Ethnopharmacol. 2011, 133:773-779.
12. Glass C.K., Saijo K., Winner B., Marchetto M.C., Gage F.H. Mechanisms underlying inflammation in neurodegeneration. Cell 2010, 140:918-934.
13. Heo H.J., Suh Y.M., Kim M.J., Choi S.J., Mun N.S., Kim H.K., et al. Daidzein activates choline acetyltransferase from MC-IXC cells and improves drug-induced amnesia. Biosci. Biotechnol. Biochem. 2006, 70:107-111.
14. Hoozemans J.J., Rozemuller A.J., Janssen I., De Groot C.J., Veerhuis R., Eikelenboom P. Cyclooxygenase expression in microglia and neurons in Alzheimer's disease and control brain. Acta Neuropathol. 2001, 101:2-8.
15. Hritcu L., Cioanca O., Hancianu M. Effects of lavender oil inhalation on improving scopolamine-induced spatial memory impairment in laboratory rats. Phytomedicine 2012, 19:529-534.
16. Hwang Y.W., Kim S.Y., Jee S.H., Kim Y.N., Nam C.M. Soy food consumption and risk of prostate cancer: a meta-analysis of observational studies. Nutr. Cancer 2009, 61:598-606.
17. Jang Y.J., Kim J., Shim J., Kim C.Y., Jang J.H., Lee K.W., et al. Decaffeinated coffee preventsscopolamine-induced memory impairment in rats. Behav. Brain Res. 2013, 245:113-119.
18. Korde L.A., Wu A.H., Fears T., Nomura A.M.Y., West D.W., Kolonel L.N., et al. Childhood soy intake and breast cancer risk in Asian American women. Cancer Epidem. Biomar. Prev. 2009, 18:1050-1059.
19. Kovarik Z., Radic Z., Berman H.A., Simeon-Rudolf V., Reiner E., Taylor P. Acetylcholinesterase active centre and gorge conformations analysed by combinatorial mutations and enantiomeric phosphonates. Biochem. J. 2003, 373:33-40.
20. Kulmacz R.J., Lands W.E.M. Requirements of hydroperoxide by the cyclooxygenase and peroxidase activities of prostaglandin H synthase. Prostaglandins 1983, 25:531-540.
21. Lee B., Sur B., Shim I., Lee H., Hahm D.H. Phellodendron amurense and its major alkaloid compound, berberine amelioratesscopolamine-induced neuronal impairment and memory dysfunction in rats. Korean J. Physiol. Pharmacol. 2012, 16:79-89.
22. Liang W., Lee A.H., Binns C.W., Huang R., Hu D., Shao H. Soy consumption reduces risk of ischemic stroke: a case-control study in Southern China. Neuroepidemiology 2009, 33:111-116.
23. Lio D., Licastro F., Scola L., Chiappelli M., Grimald L.M., Crivello A., et al. Interleukin-10 promoter polymorphism in sporadic Alzheimer's disease. Genes Immun. 2003, 4:234-238.
24. Mani V., Ramasamy K., Ahmad A., Parle M., Shah S.A.A., Majeed A.B.A. Protective effects of total alkaloidal extract from Murraya koenigii leaves on experimentally induced dementia. Food Chem. Toxicol. 2012, 50:1036-1044.
25. Nagarajan S., Burris R.L., Stewart B.W., Wilkerson J.E., Badger T.M. Dietary soy protein isolate ameliorates atherosclerotic lesions in apolipoprotein E-deficient mice potentially by inhibiting monocyte chemoattractant protein-1 expression. J. Nutr. 2008, 138:332-337.
26. Overk C.R., Felder C.C., Tu Y., Schober D.A., Bales K.R., Wuu J., et al. Cortical M1 receptor concentration increases without a concomitant change in function in Alzheimer's disease. J. Chem. Neuroanat. 2010, 40:63-70.
27. Park S.J., Kim D.H., Jung J.M., Kim J.M., Cai M., Liu X., et al. The ameliorating effects of stigmasterol on scopolamine-induced memory impairments in mice. Eur. J. Pharmacol. 2012, 676:64-70.
28. Patel N., Paris D., Mathura V., Quadros A., Crawford F., Mullan M. Inflammatory cytokine levels correlate with amyloid load in transgenic mouse models of Alzheimer's disease. J. Neuroinflamm. 2005, 2:9.
29. Pepeu G., Giovannini M.G. Cholinesterase inhibitors and memory. Chem. Biol. Interact. 2010, 187:403-408.
30. Pipe E.A., Gobert C.P., Capes S.E., Darlington G.A., Lampe J.W., Duncan A.M. Soy protein reduces serum LDL cholesterol and the LDL cholesterol: HDL cholesterol and apolipoprotein B: apolipoprotein A-I ratios in adults with type 2 diabetes. J. Nutr. 2009, 139:1700-1706.
31. Reynolds K., Chin A., Lees K.A., Nguyen A., Bujnowski D., He J. A meta-analysis of the effect of soy protein supplementation on serum lipids. Am. J. Cardiol. 2006, 98:633-640.
32. Rubio-Perez J.M., Morillas-Ruiz J.M. A review: inflammatory process in Alzheimer's disease, role of cytokines. Sci. World J. 2012, 756357.
33. Titus A.D.J., Shankaranarayana Rao B.S., Harsha H.N., Ramkumar K., Srikumar B.N., Singh S.B., et al. Hypobaric hypoxia-induced dendritic atrophy of hippocampal neurons is associated with cognitive impairment in adult rats. Neurosci. 2007, 145:265-278.
34. Tota S., Hanif K., Kamat P.K., Najmi A.K., Nath C. Role of central angiotensin receptors inscopolamine-induced impairment in memory, cerebral blood flow, and cholinergic function. Psychopharmacology 2012, 222:185-202.
35. Town T., Nikolic V., Tan J. The microglial "activation" continuum: from innate to adaptive responses. J. Neuroinflamm. 2005, 2:1-10.
36. Vasudevan M., Parle M. Memory enhancing activity of Anwala churna (Emblica officinalis Gaertn.): an Ayurvedic preparation. Physiol. Behav. 2007, 91:46-54.
37. Villa P., Costantini B., Suriano R., Perri C., Macri F., Ricciardi L., et al. The differential effect of the phytoestrogen genistein on cardiovascular risk factors in postmenopausal women: relationship with the metabolic status. J. Clin. Endocrinol. Metab. 2009, 94:552-558.
38. Vizi E.S., Harsinc L., Duncalf D., Nagashima H., Potter P., Foldes F.F. A simple and sensitive method of acetylcholine identification and assay: bioassay combined with minicolumn gel filtration or high-performance liquid chromatography. J. Pharmacol. Method 1985, 13:201-211.
39. Wang J., Chen F., Zheng P., Deng W., Yuan J., Peng B., et al. Huperzine A ameliorates experimental autoimmune encephalomyelitis via the suppression of T cell-mediated neuronal inflammation in mice. Exp. Neurol. 2012, 236:79-87.
40. Wei Q.K., Jone W.W., Fang T.J. Study on isoflavones isomers contents in Taiwan's soybean and GM soybean. J. Food Drug Anal. 2004, 12:324-331.
41. Winter C.D., Iannotti F., Pringle A.K., Trikkas C., Clough G.F., Church M.K. A microdialysis method for the recovery of IL-1β, IL-6 and nerve growth factor from human brain in vivo. J. Neurosci. Methods 2002, 119:45-50.
42. Yang H., Jin G., Ren D., Luo S., Zhou T. Mechanism of isoflavone aglycone's effect on cognitive performance of senescence-accelerated mice. Brain Cognition 2011, 76:206-210.