Mechanism of isoflavone aglycone's effect on cognitive performance of senescence-accelerated mice

Brain and Cognition

Volumn 76, Issue 1, 2011, Pages 206-210

  Yang, Hong ^a,b   Jin, Guifang ^b   Ren, Dongdong ^b   Luo, Sijing ^b   Zhou, Tianhong ^a  

^a JINAN UNIVERSITY   (China)

^b GUANGDONG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Secretase; Acetylcholinesterase; Isoflavone aglycone; Learning and memory; Senescence accelerated mice

Indexed keywords

ACETYLCHOLINE; ACETYLCHOLINESTERASE; BETA SECRETASE; ESTRADIOL; GLUTATHIONE PEROXIDASE; ISOFLAVONE AGLYCONE; ISOFLAVONE DERIVATIVE; MALONALDEHYDE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CELL COUNT; CHOLINERGIC ACTIVITY; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFECT; DRUG MECHANISM; DRUG MEGADOSE; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; ENZYME INHIBITION; ENZYME REGULATION; LOW DRUG DOSE; MALE; MAZE TEST; MEMORY; MENTAL CAPACITY; MENTAL PERFORMANCE; MENTAL TEST; MOUSE; NERVE CELL LESION; NEUROPROTECTION; NONHUMAN; PERCEPTIVE DISCRIMINATION; PRIORITY JOURNAL; SENESCENCE ACCELERATED MOUSE;

ACETYLCHOLINESTERASE; AGING; AMYLOID PRECURSOR PROTEIN SECRETASES; ANALYSIS OF VARIANCE; ANIMALS; CEREBRAL CORTEX; COGNITION; HIPPOCAMPUS; ISOFLAVONES; MALE; MAZE LEARNING; MICE; NEURONS; PLANT EXTRACTS; RANDOM ALLOCATION; SUPEROXIDE DISMUTASE;

EID: 79955106390     PISSN: 02782626     EISSN: 10902147     Source Type: Journal    
DOI: 10.1016/j.bandc.2010.10.008     Document Type: Article

References (21)

1. Bang O., Hong H., Kim D., Boo J. Neuroprotective effect of genistein against beta amyloid-induced neurotoxicity. Neurobiology of Disease 2004, 16:21-28.
2. Chan Y.C., Hosoda K., Tsai C.J., Yamamoto S., Wang M.F. Favorable effects of tea on reducing the cognitive deficits and brain morphological changes in senescence-accelerated mice. Journal of Nutritional Science and Vitaminology (Tokyo) 2006, 52(4):266-273.
3. Flood J.F., Farr S.A., Uezu K., John E.M. Age-related changes in septal serotonergic, gabaergic and glutamatergic facilitation of retention in SAMP 8 mice. Mechanisms of Ageing and Development 1998, 105(122):173-188.
4. Frost D., Gorman P.M., Yip C.M. Co-incorporation of Abeta 40 and Abeta42 to form mixed pre-fibrillar aggregates. European Journal of Biochemistry 2003, 270(4):654.
5. Jefremov V., Rakitin A., Mahlapuu R., Zilmer K., Bogdanovic N., Zilmer M., et al. 17beta-oestradiol stimulation of G-proteins in aged and Alzheimer's human brain: Comparison with phytoestrogens. Journal of Neuroendocrinology 2008, 20:587-596.
6. Li Q.M., Meng R.S., Wei C.X., Kan F.J., Huang Q.H. Effects of Naohuandan Recipe on learning and memory abilities of SAM-P/8 mice and its role in anti-oxidation and anti-apoptosis. Journal of Chinese Integrative Medicine 2006, 4(1):48-51.
7. Liao J.W., Hsu C.K., Wang M.F., Hsu W.M., Chan Y.C. Beneficial effect of Toona sinensis Roemor on improving cognitive performance and brain degeneration in senescence-accelerated mice. British Journal of Nutrition 2006, 96(2):400-407.
8. Liu Y.F., Shi X.M., Han J.X. Effect of acupuncture on senescence accelerate mouse P 10 (SAMP10) behavior in experimental research. Chinese Acupuncture 2002, 22(5):327-330.
9. Ma D.L., Hu H.T., Yang P.B., Jin H., Ren H.M., Liu Y. Protective effect of rAAV vector mediated hBDNF on rat basal forebrain cholinergic neurons damaged by amyloid β-peptide. Journal of Xi'an Jiaotong University (Medical Sciences) 2004, 25(1):27-29.
10. Petursdottir A.L., Farr S.A., Morley J.E., Banks W.A., Skuladottir G.V. Lipid peroxidation in brain during aging in the senescence-accelerated mouse (SAM). Neurobiology of Aging 2007, 28(8):1170-1178.
11. Rossouw J.E., Anderson G.L., Prentice R.L. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: Principal results from the women health initiative randomized controlled tria1. Journal of the American Medical Association 2002, 288(3):321-333.
12. Sarkaki A., Amani R., Badavi M., Moghaddam A.Z., Aligholi H., Safahani M., et al. Pre-treatment effect of different doses of soy isoflavones on spatial learning and memory in an ovariectomized animal model of Alzheimer's disease. Pakistan Journal of Biological Sciences 2008, 11(8):1114-1119.
13. Shi Q., Gibson G.E. Oxidative stress and transcriptional regulation in Alzheimer's disease. Alzheimer Disease & Associated Disorders 2007, 21(4):276-291.
14. Talesa V.N. Acetylcholinesterase in Alzheimer's disease. Mechanisms of Ageing and Development 2001, 122(16):1961-1969.
15. Townsend K.P., Obregon D., Quadtros A., Patel N., Volmar Ch., Paris D., et al. Proinflammatory and vasoactive effects of Abeta in the cerebrovasculature. Annals of the New York Academy of Sciences 2002, 977:65.
16. Tyler S.J., Dawbarn D., Wilcock G.K., Allen S.J. Alpha- and beta-secretase: Profound changes in Alzheimer' s disease. Biochemical and Biophysical Research Communications 2002, 299:373-376.
17. Yang H., Chen W.Q., Zhao Y.H. Effect of soybean isoflavones active-extracts on learning and memory in AD mice. Chinese Traditional and Herbal Drug 2005, 36(6):885-886.
18. Yang H., Chen W.Q., Zhao Y.H. The protective effect of components of isoflavones on the PC12 cells damage induced by Aβ1-42. Chinese Pharmacological Bulletin 2005, 21(9):1089-1091.
19. Yang W.M., Yang J.F., Chen B., Han M.X., Li Z.G., Zhang G.L., et al. Effects of Zhinao capsule on learning, memory and cerebral cholinergic neurotransmitter system in rat models of Alzheimer disease. Chinese Journal of Clinical Rehabilitation 2004, 8(28):6262-6264.
20. Yatin S., Aksenov M., Butterfield D.A. The antioxidant vitamin E modulates amyloid beta 2 peptide-induced creatine kinase activity inhibition and increased protein oxidation: Implications for the free radical hypothesis of Alzheimer's disease. Neurochemical Research 1999, 24(3):427-435.
21. Zhang J., Yan F.L., Guan X.N. Effect of Egb761 on activity of β-secretase in hippocampus of old rats after chronic cerebral hypoperfusion. Chinese Clinical Neural Science 2006, 14(5):454-457.