-
1
-
-
78650173611
-
Disruption of central nervous system barriers in multiple sclerosis
-
Alvarez J.I., Cayrol R., Prat A. Disruption of central nervous system barriers in multiple sclerosis. Biochim. Biophys. Acta 2011, 1812:252-264.
-
(2011)
Biochim. Biophys. Acta
, vol.1812
, pp. 252-264
-
-
Alvarez, J.I.1
Cayrol, R.2
Prat, A.3
-
2
-
-
0034098365
-
Huperzine A, a potential therapeutic agent for treatment of Alzheimer's disease
-
Bai D.L., Tang X.C., He X.C. Huperzine A, a potential therapeutic agent for treatment of Alzheimer's disease. Curr. Med. Chem. 2000, 7:355-374.
-
(2000)
Curr. Med. Chem.
, vol.7
, pp. 355-374
-
-
Bai, D.L.1
Tang, X.C.2
He, X.C.3
-
3
-
-
0031910978
-
Donepezil use in Alzheimer disease
-
Barner E.L., Gray S.L. Donepezil use in Alzheimer disease. Ann. Pharmacother. 1998, 32:70-77.
-
(1998)
Ann. Pharmacother.
, vol.32
, pp. 70-77
-
-
Barner, E.L.1
Gray, S.L.2
-
4
-
-
64549094161
-
Administration of a monomeric CCL2 variant to EAE mice inhibits inflammatory cell recruitment and protects from demyelination and axonal loss
-
Brini E., Ruffini F., Bergami A., Brambilla E., Dati G., Greco B., Cirillo R., Proudfoot A.E., Comi G., Furlan R., Zaratin P., Martino G. Administration of a monomeric CCL2 variant to EAE mice inhibits inflammatory cell recruitment and protects from demyelination and axonal loss. J. Neuroimmunol. 2009, 209:33-39.
-
(2009)
J. Neuroimmunol.
, vol.209
, pp. 33-39
-
-
Brini, E.1
Ruffini, F.2
Bergami, A.3
Brambilla, E.4
Dati, G.5
Greco, B.6
Cirillo, R.7
Proudfoot, A.E.8
Comi, G.9
Furlan, R.10
Zaratin, P.11
Martino, G.12
-
5
-
-
50649113266
-
[+]-Huperzine A treatment protects against N-methyl-d-aspartate-induced seizure/status epilepticus in rats
-
Coleman B.R., Ratcliffe R.H., Oguntayo S.A., Shi X., Doctor B.P., Gordon R.K., Nambiar M.P. [+]-Huperzine A treatment protects against N-methyl-d-aspartate-induced seizure/status epilepticus in rats. Chem. Biol. Interact. 2008, 175:387-395.
-
(2008)
Chem. Biol. Interact.
, vol.175
, pp. 387-395
-
-
Coleman, B.R.1
Ratcliffe, R.H.2
Oguntayo, S.A.3
Shi, X.4
Doctor, B.P.5
Gordon, R.K.6
Nambiar, M.P.7
-
6
-
-
54149084585
-
Multiple sclerosis
-
Compston A., Coles A. Multiple sclerosis. Lancet 2008, 372:1502-1517.
-
(2008)
Lancet
, vol.372
, pp. 1502-1517
-
-
Compston, A.1
Coles, A.2
-
7
-
-
80053300497
-
Experimental autoimmune encephalomyelitis (EAE) as a model for multiple sclerosis (MS)
-
Constantinescu C.S., Farooqi N., O'Brien K., Gran B. Experimental autoimmune encephalomyelitis (EAE) as a model for multiple sclerosis (MS). Br. J. Pharmacol. 2011, 164:1079-1106.
-
(2011)
Br. J. Pharmacol.
, vol.164
, pp. 1079-1106
-
-
Constantinescu, C.S.1
Farooqi, N.2
O'Brien, K.3
Gran, B.4
-
8
-
-
0016669402
-
Vesicular disruption of myelin in autoimmune demyelination
-
Dalcanto M.C., Wisniewski H.M., Johnson A.B., Brostoff S.W., Raine C.S. Vesicular disruption of myelin in autoimmune demyelination. J. Neurol. Sci. 1975, 24:313-319.
-
(1975)
J. Neurol. Sci.
, vol.24
, pp. 313-319
-
-
Dalcanto, M.C.1
Wisniewski, H.M.2
Johnson, A.B.3
Brostoff, S.W.4
Raine, C.S.5
-
9
-
-
62949139899
-
Role of huperzine a in the treatment of Alzheimer's disease
-
Desilets A.R., Gickas J.J., Dunican K.C. Role of huperzine a in the treatment of Alzheimer's disease. Ann. Pharmacother. 2009, 43:514-518.
-
(2009)
Ann. Pharmacother.
, vol.43
, pp. 514-518
-
-
Desilets, A.R.1
Gickas, J.J.2
Dunican, K.C.3
-
10
-
-
36549059089
-
Changes in the activation level of NF-kappa B in lymphocytes of MS patients during glucocorticoid pulse therapy
-
Eggert M., Goertsches R., Seeck U., Dilk S., Neeck G., Zettl U.K. Changes in the activation level of NF-kappa B in lymphocytes of MS patients during glucocorticoid pulse therapy. J. Neurol. Sci. 2008, 264:145-150.
-
(2008)
J. Neurol. Sci.
, vol.264
, pp. 145-150
-
-
Eggert, M.1
Goertsches, R.2
Seeck, U.3
Dilk, S.4
Neeck, G.5
Zettl, U.K.6
-
11
-
-
77954563548
-
Current views on the roles of Th1 and Th17 cells in experimental autoimmune encephalomyelitis
-
El-behi M., Rostami A., Ciric B. Current views on the roles of Th1 and Th17 cells in experimental autoimmune encephalomyelitis. J. Neuroimmune Pharmacol. 2010, 5:189-197.
-
(2010)
J. Neuroimmune Pharmacol.
, vol.5
, pp. 189-197
-
-
El-behi, M.1
Rostami, A.2
Ciric, B.3
-
12
-
-
35748931165
-
A new acetylcholinesterase inhibitor with anti-PAF activity modulates oxidative stress and pro-inflammatory mediators release in stimulated RAW 264.7 macrophage cells. Comparison with tacrine
-
Ezoulin M.J., Liu Z., Dutertre-Catella H., Wu G., Dong C.Z., Heymans F., Ombetta J.E., Rat P., Massicot F. A new acetylcholinesterase inhibitor with anti-PAF activity modulates oxidative stress and pro-inflammatory mediators release in stimulated RAW 264.7 macrophage cells. Comparison with tacrine. Int. Immunopharmacol. 2007, 7:1685-1694.
-
(2007)
Int. Immunopharmacol.
, vol.7
, pp. 1685-1694
-
-
Ezoulin, M.J.1
Liu, Z.2
Dutertre-Catella, H.3
Wu, G.4
Dong, C.Z.5
Heymans, F.6
Ombetta, J.E.7
Rat, P.8
Massicot, F.9
-
13
-
-
79551718102
-
Prevention of clinical and histological signs of proteolipid protein (PLP)-induced experimental allergic encephalomyelitis (EAE) in mice by the water-soluble carbon monoxide-releasing molecule (CORM)-A1
-
Fagone P., Mangano K., Quattrocchi C., Motterlini R., Di Marco R., Magro G., Penacho N., Romao C.C., Nicoletti F. Prevention of clinical and histological signs of proteolipid protein (PLP)-induced experimental allergic encephalomyelitis (EAE) in mice by the water-soluble carbon monoxide-releasing molecule (CORM)-A1. Clin. Exp. Immunol. 2011, 163:368-374.
-
(2011)
Clin. Exp. Immunol.
, vol.163
, pp. 368-374
-
-
Fagone, P.1
Mangano, K.2
Quattrocchi, C.3
Motterlini, R.4
Di Marco, R.5
Magro, G.6
Penacho, N.7
Romao, C.C.8
Nicoletti, F.9
-
14
-
-
79953275300
-
A systematic review of single Chinese herbs for Alzheimer's disease treatment
-
Fu L.M., Li J.T. A systematic review of single Chinese herbs for Alzheimer's disease treatment. Evid. Based Complement. Altern. Med. 2009, 10.1093/ecam/nep1136.
-
(2009)
Evid. Based Complement. Altern. Med.
-
-
Fu, L.M.1
Li, J.T.2
-
15
-
-
1642317079
-
Antibody targeting of the CC chemokine ligand 5 results in diminished leukocyte infiltration into the central nervous system and reduced neurologic disease in a viral model of multiple sclerosis
-
Glass W.G., Hickey M.J., Hardison J.L., Liu M.T., Manning J.E., Lane T.E. Antibody targeting of the CC chemokine ligand 5 results in diminished leukocyte infiltration into the central nervous system and reduced neurologic disease in a viral model of multiple sclerosis. J. Immunol. 2004, 172:4018-4025.
-
(2004)
J. Immunol.
, vol.172
, pp. 4018-4025
-
-
Glass, W.G.1
Hickey, M.J.2
Hardison, J.L.3
Liu, M.T.4
Manning, J.E.5
Lane, T.E.6
-
16
-
-
79960600801
-
Huperzine a as potential treatment of Alzheimer's disease: an assessment on chemistry, pharmacology, and clinical studies
-
Ha G.T., Wong R.K., Zhang Y. Huperzine a as potential treatment of Alzheimer's disease: an assessment on chemistry, pharmacology, and clinical studies. Chem. Biodivers. 2011, 8:1189-1204.
-
(2011)
Chem. Biodivers.
, vol.8
, pp. 1189-1204
-
-
Ha, G.T.1
Wong, R.K.2
Zhang, Y.3
-
17
-
-
78650957430
-
Attenuation of CNS inflammatory responses by nicotine involves alpha7 and non-alpha7 nicotinic receptors
-
Hao J., Simard A.R., Turner G.H., Wu J., Whiteaker P., Lukas R.J., Shi F.D. Attenuation of CNS inflammatory responses by nicotine involves alpha7 and non-alpha7 nicotinic receptors. Exp. Neurol. 2011, 227:110-119.
-
(2011)
Exp. Neurol.
, vol.227
, pp. 110-119
-
-
Hao, J.1
Simard, A.R.2
Turner, G.H.3
Wu, J.4
Whiteaker, P.5
Lukas, R.J.6
Shi, F.D.7
-
18
-
-
27544490377
-
Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
-
Harrington L.E., Hatton R.D., Mangan P.R., Turner H., Murphy T.L., Murphy K.M., Weaver C.T. Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat. Immunol. 2005, 6:1123-1132.
-
(2005)
Nat. Immunol.
, vol.6
, pp. 1123-1132
-
-
Harrington, L.E.1
Hatton, R.D.2
Mangan, P.R.3
Turner, H.4
Murphy, T.L.5
Murphy, K.M.6
Weaver, C.T.7
-
19
-
-
79952489970
-
EAE: imperfect but useful models of multiple sclerosis
-
Hart B.A., Gran B., Weissert R. EAE: imperfect but useful models of multiple sclerosis. Trends Mol. Med. 2011, 17:119-125.
-
(2011)
Trends Mol. Med.
, vol.17
, pp. 119-125
-
-
Hart, B.A.1
Gran, B.2
Weissert, R.3
-
20
-
-
44649119542
-
Huperzine A provides neuroprotection against several cell death inducers using in vitro model systems of motor neuron cell death
-
Hemendinger R.A., Armstrong E.J., Persinski R., Todd J., Mougeot J.L., Volvovitz F., Rosenfeld J. Huperzine A provides neuroprotection against several cell death inducers using in vitro model systems of motor neuron cell death. Neurotox. Res. 2008, 13:49-61.
-
(2008)
Neurotox. Res.
, vol.13
, pp. 49-61
-
-
Hemendinger, R.A.1
Armstrong, E.J.2
Persinski, R.3
Todd, J.4
Mougeot, J.L.5
Volvovitz, F.6
Rosenfeld, J.7
-
21
-
-
13244283212
-
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
-
Langrish C.L., Chen Y., Blumenschein W.M., Mattson J., Basham B., Sedgwick J.D., McClanahan T., Kastelein R.A., Cua D.J. IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J. Exp. Med. 2005, 201:233-240.
-
(2005)
J. Exp. Med.
, vol.201
, pp. 233-240
-
-
Langrish, C.L.1
Chen, Y.2
Blumenschein, W.M.3
Mattson, J.4
Basham, B.5
Sedgwick, J.D.6
McClanahan, T.7
Kastelein, R.A.8
Cua, D.J.9
-
22
-
-
80052441353
-
Treatment of myasthenia gravis: focus on pyridostigmine
-
Maggi L., Mantegazza R. Treatment of myasthenia gravis: focus on pyridostigmine. Clin. Drug Invest. 2011, 31:691-701.
-
(2011)
Clin. Drug Invest.
, vol.31
, pp. 691-701
-
-
Maggi, L.1
Mantegazza, R.2
-
23
-
-
30344481086
-
Modulating CCR2 and CCL2 at the blood-brain barrier: relevance for multiple sclerosis pathogenesis
-
Mahad D., Callahan M.K., Williams K.A., Ubogu E.E., Kivisakk P., Tucky B., Kidd G., Kingsbury G.A., Chang A., Fox R.J., Mack M., Sniderman M.B., Ravid R., Staugaitis S.M., Stins M.F., Ransohoff R.M. Modulating CCR2 and CCL2 at the blood-brain barrier: relevance for multiple sclerosis pathogenesis. Brain 2006, 129:212-223.
-
(2006)
Brain
, vol.129
, pp. 212-223
-
-
Mahad, D.1
Callahan, M.K.2
Williams, K.A.3
Ubogu, E.E.4
Kivisakk, P.5
Tucky, B.6
Kidd, G.7
Kingsbury, G.A.8
Chang, A.9
Fox, R.J.10
Mack, M.11
Sniderman, M.B.12
Ravid, R.13
Staugaitis, S.M.14
Stins, M.F.15
Ransohoff, R.M.16
-
24
-
-
33645237919
-
Anti-inflammatory properties of cholinergic up-regulation: a new role for acetylcholinesterase inhibitors
-
Nizri E., Hamra-Amitay Y., Sicsic C., Lavon I., Brenner T. Anti-inflammatory properties of cholinergic up-regulation: a new role for acetylcholinesterase inhibitors. Neuropharmacology 2006, 50:540-547.
-
(2006)
Neuropharmacology
, vol.50
, pp. 540-547
-
-
Nizri, E.1
Hamra-Amitay, Y.2
Sicsic, C.3
Lavon, I.4
Brenner, T.5
-
25
-
-
53149137393
-
Suppression of neuroinflammation and immunomodulation by the acetylcholinesterase inhibitor rivastigmine
-
Nizri E., Irony-Tur-Sinai M., Faranesh N., Lavon I., Lavi E., Weinstock M., Brenner T. Suppression of neuroinflammation and immunomodulation by the acetylcholinesterase inhibitor rivastigmine. J. Neuroimmunol. 2008, 203:12-22.
-
(2008)
J. Neuroimmunol.
, vol.203
, pp. 12-22
-
-
Nizri, E.1
Irony-Tur-Sinai, M.2
Faranesh, N.3
Lavon, I.4
Lavi, E.5
Weinstock, M.6
Brenner, T.7
-
26
-
-
56949087765
-
Brain acetylcholinesterase activity controls systemic cytokine levels through the cholinergic anti-inflammatory pathway
-
Pavlov V.A., Parrish W.R., Rosas-Ballina M., Ochani M., Puerta M., Ochani K., Chavan S., Al-Abed Y., Tracey K.J. Brain acetylcholinesterase activity controls systemic cytokine levels through the cholinergic anti-inflammatory pathway. Brain Behav. Immun. 2009, 23:41-45.
-
(2009)
Brain Behav. Immun.
, vol.23
, pp. 41-45
-
-
Pavlov, V.A.1
Parrish, W.R.2
Rosas-Ballina, M.3
Ochani, M.4
Puerta, M.5
Ochani, K.6
Chavan, S.7
Al-Abed, Y.8
Tracey, K.J.9
-
27
-
-
14844322281
-
Acetylcholinesterase inhibitors effects on oncostatin-M, interleukin-1 beta and interleukin-6 release from lymphocytes of Alzheimer's disease patients
-
Reale M., Iarlori C., Gambi F., Lucci I., Salvatore M., Gambi D. Acetylcholinesterase inhibitors effects on oncostatin-M, interleukin-1 beta and interleukin-6 release from lymphocytes of Alzheimer's disease patients. Exp. Gerontol. 2005, 40:165-171.
-
(2005)
Exp. Gerontol.
, vol.40
, pp. 165-171
-
-
Reale, M.1
Iarlori, C.2
Gambi, F.3
Lucci, I.4
Salvatore, M.5
Gambi, D.6
-
28
-
-
33645227116
-
The acetylcholinesterase inhibitor, Donepezil, regulates a Th2 bias in Alzheimer's disease patients
-
Reale M., Iarlori C., Gambi F., Feliciani C., Isabella L., Gambi D. The acetylcholinesterase inhibitor, Donepezil, regulates a Th2 bias in Alzheimer's disease patients. Neuropharmacology 2006, 50:606-613.
-
(2006)
Neuropharmacology
, vol.50
, pp. 606-613
-
-
Reale, M.1
Iarlori, C.2
Gambi, F.3
Feliciani, C.4
Isabella, L.5
Gambi, D.6
-
29
-
-
47849132772
-
Peripheral chemokine receptors, their ligands, cytokines and Alzheimer's disease
-
Reale M., Iarlori C., Feliciani C., Gambi D. Peripheral chemokine receptors, their ligands, cytokines and Alzheimer's disease. J. Alzheimers Dis. 2008, 14:147-159.
-
(2008)
J. Alzheimers Dis.
, vol.14
, pp. 147-159
-
-
Reale, M.1
Iarlori, C.2
Feliciani, C.3
Gambi, D.4
-
30
-
-
67849103549
-
Clinical use of an herbal-derived compound (Huperzine A) to treat putative complex partial seizures in a dog
-
Schneider B.M., Dodman N.H., Faissler D., Ogata N. Clinical use of an herbal-derived compound (Huperzine A) to treat putative complex partial seizures in a dog. Epilepsy Behav. 2009, 15:529-534.
-
(2009)
Epilepsy Behav.
, vol.15
, pp. 529-534
-
-
Schneider, B.M.1
Dodman, N.H.2
Faissler, D.3
Ogata, N.4
-
31
-
-
17644396349
-
Immunology of multiple sclerosis
-
Sospedra M., Martin R. Immunology of multiple sclerosis. Annu. Rev. Immunol. 2005, 23:683-747.
-
(2005)
Annu. Rev. Immunol.
, vol.23
, pp. 683-747
-
-
Sospedra, M.1
Martin, R.2
-
32
-
-
33846817498
-
Physiology and immunology of the cholinergic antiinflammatory pathway
-
Tracey K.J. Physiology and immunology of the cholinergic antiinflammatory pathway. J. Clin. Invest. 2007, 117:289-296.
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 289-296
-
-
Tracey, K.J.1
-
34
-
-
0037461768
-
Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation
-
Wang H., Yu M., Ochani M., Amella C.A., Tanovic M., Susarla S., Li J.H., Wang H., Yang H., Ulloa L., Al-Abed Y., Czura C.J., Tracey K.J. Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation. Nature 2003, 421:384-388.
-
(2003)
Nature
, vol.421
, pp. 384-388
-
-
Wang, H.1
Yu, M.2
Ochani, M.3
Amella, C.A.4
Tanovic, M.5
Susarla, S.6
Li, J.H.7
Wang, H.8
Yang, H.9
Ulloa, L.10
Al-Abed, Y.11
Czura, C.J.12
Tracey, K.J.13
-
35
-
-
30144437522
-
Progress in studies of huperzine A, a natural cholinesterase inhibitor from Chinese herbal medicine
-
Wang R., Yan H., Tang X.C. Progress in studies of huperzine A, a natural cholinesterase inhibitor from Chinese herbal medicine. Acta Pharmacol. Sin. 2006, 27:1-26.
-
(2006)
Acta Pharmacol. Sin.
, vol.27
, pp. 1-26
-
-
Wang, R.1
Yan, H.2
Tang, X.C.3
-
36
-
-
33744517635
-
Effects of huperzine A on memory deficits and neurotrophic factors production after transient cerebral ischemia and reperfusion in mice
-
Wang Z.F., Tang L.L., Yan H., Wang Y.J., Tang X.C. Effects of huperzine A on memory deficits and neurotrophic factors production after transient cerebral ischemia and reperfusion in mice. Pharmacol. Biochem. Behav. 2006, 83:603-611.
-
(2006)
Pharmacol. Biochem. Behav.
, vol.83
, pp. 603-611
-
-
Wang, Z.F.1
Tang, L.L.2
Yan, H.3
Wang, Y.J.4
Tang, X.C.5
-
37
-
-
48749121734
-
Huperzine A exhibits anti-inflammatory and neuroprotective effects in a rat model of transient focal cerebral ischemia
-
Wang Z.F., Wang J., Zhang H.Y., Tang X.C. Huperzine A exhibits anti-inflammatory and neuroprotective effects in a rat model of transient focal cerebral ischemia. J. Neurochem. 2008, 106:1594-1603.
-
(2008)
J. Neurochem.
, vol.106
, pp. 1594-1603
-
-
Wang, Z.F.1
Wang, J.2
Zhang, H.Y.3
Tang, X.C.4
-
38
-
-
67349262023
-
Efficacy and safety of natural acetylcholinesterase inhibitor huperzine A in the treatment of Alzheimer's disease: an updated meta-analysis
-
Wang B.S., Wang H., Wei Z.H., Song Y.Y., Zhang L., Chen H.Z. Efficacy and safety of natural acetylcholinesterase inhibitor huperzine A in the treatment of Alzheimer's disease: an updated meta-analysis. J. Neural Transm. 2009, 116:457-465.
-
(2009)
J. Neural Transm.
, vol.116
, pp. 457-465
-
-
Wang, B.S.1
Wang, H.2
Wei, Z.H.3
Song, Y.Y.4
Zhang, L.5
Chen, H.Z.6
-
39
-
-
76549112494
-
Huperzine a improves chronic inflammation and cognitive decline in rats with cerebral hypoperfusion
-
Wang J., Zhang H.Y., Tang X.C. Huperzine a improves chronic inflammation and cognitive decline in rats with cerebral hypoperfusion. J. Neurosci. Res. 2010, 88:807-815.
-
(2010)
J. Neurosci. Res.
, vol.88
, pp. 807-815
-
-
Wang, J.1
Zhang, H.Y.2
Tang, X.C.3
-
40
-
-
77951837763
-
Trafficking of immune cells in the central nervous system
-
Wilson E.H., Weninger W., Hunter C.A. Trafficking of immune cells in the central nervous system. J. Clin. Invest. 2010, 120:1368-1379.
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 1368-1379
-
-
Wilson, E.H.1
Weninger, W.2
Hunter, C.A.3
-
41
-
-
0043204247
-
The psychopharmacology of huperzine A: an alkaloid with cognitive enhancing and neuroprotective properties of interest in the treatment of Alzheimer's disease
-
Zangara A. The psychopharmacology of huperzine A: an alkaloid with cognitive enhancing and neuroprotective properties of interest in the treatment of Alzheimer's disease. Pharmacol. Biochem. Behav. 2003, 75:675-686.
-
(2003)
Pharmacol. Biochem. Behav.
, vol.75
, pp. 675-686
-
-
Zangara, A.1
-
42
-
-
0037189932
-
Huperzine A attenuates apoptosis and mitochondria-dependent caspase-3 in rat cortical neurons
-
Zhou J., Tang X.C. Huperzine A attenuates apoptosis and mitochondria-dependent caspase-3 in rat cortical neurons. FEBS Lett. 2002, 526:21-25.
-
(2002)
FEBS Lett.
, vol.526
, pp. 21-25
-
-
Zhou, J.1
Tang, X.C.2
|