Crystal structure of lactose permease in complex with an affinity inactivator yields unique insight into sugar recognition

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 23, 2011, Pages 9361-9366

  Chaptal, Vincent ^a   Kwon, Seunghyug ^a   Sawaya, Michael R ^b   Guan, Lan ^c   Kaback, H Ronald ^a   Abramson, Jeff ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER SCHOOL OF MEDICINE   (United States)

Author keywords

Affinity labeling; Bioenergetics; Membrane protein crystal structure; MTS reagents; Sugar binding

Indexed keywords

CARBOHYDRATE DERIVATIVE; DISULFIDE; HYDROXYL GROUP; LACTOSE PERMEASE; METHANETHIOSULFONYL GALACTOPYRANOSIDE; SUGAR; UNCLASSIFIED DRUG;

AFFINITY LABELING; ARTICLE; BINDING AFFINITY; BIOCHEMISTRY; CRYSTAL STRUCTURE; CYTOPLASM; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL;

AMINO ACID SUBSTITUTION; BINDING SITES; BIOLOGICAL TRANSPORT; CRYSTALLIZATION; CYSTEINE; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GALACTOSE; LACTOSE; MEMBRANE TRANSPORT PROTEINS; MESYLATES; MODELS, MOLECULAR; MONOSACCHARIDE TRANSPORT PROTEINS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; SUBSTRATE SPECIFICITY; SYMPORTERS; X-RAY DIFFRACTION;

ESCHERICHIA COLI;

EID: 79959349280     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1105687108     Document Type: Article

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