Zipping and Unzipping of Adenylate Kinase: Atomistic Insights into the Ensemble of Open ↔ Closed Transitions

Journal of Molecular Biology

Volumn 394, Issue 1, 2009, Pages 160-176

  Beckstein, Oliver ^a,b   Denning, Elizabeth J ^b   Perilla, Juan R ^b   Woolf, Thomas B ^b  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

adenylate kinase; free energy; importance sampling; molecular dynamics; transitions

Indexed keywords

ADENYLATE KINASE;

ARTICLE; COMPUTER SIMULATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENERGY YIELD; FLUORESCENCE RESONANCE ENERGY TRANSFER; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FOLDING; STRUCTURE ANALYSIS; THERMODYNAMICS;

ADENYLATE KINASE; ANIMALS; COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMANS; PROTEIN STRUCTURE, TERTIARY; SALTS; SURFACE PROPERTIES; THERMODYNAMICS;

EID: 70350146298     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2009.09.009     Document Type: Article

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