The novel isoxazoline ectoparasiticide fluralaner: Selective inhibition of arthropod γ-aminobutyric acid- and l-glutamate-gated chloride channels and insecticidal/acaricidal activity

Insect Biochemistry and Molecular Biology

Volumn 45, Issue 1, 2014, Pages 111-124

  Gassel, Michael ^a   Wolf, Christian ^a   Noack, Sandra ^a   Williams, Heike ^a   Ilg, Thomas ^a  

^a Intervet Innovation GmbH   (Germany)

Author keywords

Cat flea; Cattle tick; Ectoparasiticidal target; Fipronil; Fluralaner; GABA gated chloride channel; Glutamate gated chloride channel; Isoxazoline

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID RECEPTOR BLOCKING AGENT; A1443 COMPOUND; CHLORIDE CHANNEL; COMPLEMENTARY DNA; DIELDRIN; DRUG DERIVATIVE; FIPRONIL; FLURALANER; INSECT PROTEIN; INSECTICIDE; ISOXAZOLE DERIVATIVE; ISOXAZOLINE; PICROTOXIN; PICROTOXININ; PYRAZOLE DERIVATIVE;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; CATTLE TICK; CHEMISTRY; CTENOCEPHALIDES; DROSOPHILA MELANOGASTER; DRUG ANTAGONISM; ECTOPARASITICIDAL TARGET; GABA-GATED CHLORIDE CHANNEL; GENETICS; GLUTAMATE-GATED CHLORIDE CHANNEL; HEK293 CELL LINE; HUMAN; MOLECULAR CLONING; MOLECULAR GENETICS; PHYLOGENY; PHYSIOLOGY; RHIPICEPHALUS; SEQUENCE ALIGNMENT; XENOPUS LAEVIS;

CAT FLEA; CATTLE TICK; ECTOPARASITICIDAL TARGET; FIPRONIL; FLURALANER; GABA-GATED CHLORIDE CHANNEL; GLUTAMATE-GATED CHLORIDE CHANNEL; ISOXAZOLINE;

AMINO ACID SEQUENCE; ANIMALS; CHLORIDE CHANNELS; CLONING, MOLECULAR; CTENOCEPHALIDES; DIELDRIN; DNA, COMPLEMENTARY; DROSOPHILA MELANOGASTER; GABA ANTAGONISTS; GAMMA-AMINOBUTYRIC ACID; HEK293 CELLS; HUMANS; INSECT PROTEINS; INSECTICIDES; ISOXAZOLES; MOLECULAR SEQUENCE DATA; PHYLOGENY; PICROTOXIN; PYRAZOLES; RHIPICEPHALUS; SEQUENCE ALIGNMENT; XENOPUS LAEVIS;

EID: 84892463615     PISSN: 09651748     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ibmb.2013.11.009     Document Type: Article

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