RdlDv, a novel GABA-gated chloride channel gene from the American dog tick Dermacentor variabilis

Insect Biochemistry and Molecular Biology

Volumn 33, Issue 6, 2003, Pages 595-599

  Zheng, Y ^a   Priest, B ^a   Cully, D F ^a   Ludmerer, S W ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Dermacentor; GABA; Rdl

Indexed keywords

ACARI; ANIMALIA; BACTERIA (MICROORGANISMS); CANIS FAMILIARIS; DERMACENTOR; DERMACENTOR VARIABILIS; DROSOPHILA; DROSOPHILA VARIABILIS; INVERTEBRATA; XENOPUS;

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; CHLORIDE CHANNEL; DIELDRIN; DROSOPHILA PROTEIN; DRUG DERIVATIVE; FIPRONIL; INSECT PROTEIN; PICROTOXIN; PICROTOXININ; PYRAZOLE DERIVATIVE; RDL PROTEIN, DROSOPHILA; RECOMBINANT PROTEIN;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; BIOSYNTHESIS; CHANNEL GATING; DERMACENTOR; DOG; DRUG ANTAGONISM; GENETICS; INSECTICIDE RESISTANCE; METABOLISM; MOLECULAR CLONING; MOLECULAR GENETICS; OOCYTE; PARASITOLOGY; PATCH CLAMP; SEQUENCE HOMOLOGY; XENOPUS;

AMINO ACID SEQUENCE; ANIMALS; CHLORIDE CHANNELS; CLONING, MOLECULAR; DERMACENTOR; DIELDRIN; DOGS; DROSOPHILA PROTEINS; GAMMA-AMINOBUTYRIC ACID; INSECT PROTEINS; INSECTICIDE RESISTANCE; ION CHANNEL GATING; MOLECULAR SEQUENCE DATA; OOCYTES; PATCH-CLAMP TECHNIQUES; PICROTOXIN; PYRAZOLES; RECEPTORS, GABA-A; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; XENOPUS;

EID: 0037793224     PISSN: 09651748     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0965-1748(03)00038-9     Document Type: Article

References (30)

1. Arena, J.P., Liu, K.K., Paress, P.S., Cully, D.F., 1991. Avermectin-sensitive chloride currents induced by Caenorhabditis elegans RNA in Xenopus oocytes. Mol. Pharmacol. 40, 368-374.
2. Beaver, P.C., Jung, R.C., Cupp, E.W., 1984. In: Clinical Parasitology, ninth ed. Lea & Febiger, Philadephia, PA, pp. 581-595.
3. Belelli, D., Callachan, H., Hill-Venning, C., Peters, J.A., Lambert, J.J., 1996. Interaction of positive allosteric modulators with human and Drosophila recombinant GABA receptors expressed in Xenopus laevis oocytes. British Journal of Pharmacology 118, 563-576.
4. Cully, D.F., Vassilatis, D.K., Liu, K.K., Paress, P.S., Van der Ploeg, L.H., Schaeffer, J.M., Arena, J.P., 1994. Cloning of an avermectin-sensitive glutamate-gated chloride channel from Caenorhabditis elegans. Nature 371, 707-711.
5. Cupp, E.W., 1991. Biology of ticks. Vet. Clin. North Am. Small Anim. Pract. 21, 1-26.
6. Denny, D.J., 2001. Efficacy of fipronil against ticks. Vet. Rec. 148, 124.
7. Dent, J.A., Smith, M.M., Vassilatis, D.K., Avery, L., 2000. The genetics of ivermectin resistance in Caenorhabditis elegans. Proceedings of the National Academy of Sciences of the United States of America 97, 2674-2679.
8. Drummond, R.O., George, J.E., Kunz, S.E., 1988. Control of Arthropod Pests of Livestock: A Review of Technology. In:. CRC Press, 167.
9. A receptor locus. Proceedings of the National Academy of Sciences of the United States of America 88, 7209-7213.
10. ffrench-Constant, R.H., Rocheleau, T.A., Steichen, J.C., Chalmers, A.E., 1993. A point mutation in a Drosophila GABA receptor confers insecticide resistance. Nature 363, 449-451.
11. ffrench-Constant, R.H., 1994. The molecular and population genetics of cyclodiene insecticide resistance. Insect Biochem. Molec. Biol. 24, 335-345.
12. Forrester, S.G., Hamdan, F.F., Prichard, R.K., Beech, R.N., 1999. Cloning, sequencing, and developmental expression levels of a novel glutamate-gated chloride channel homologue in the parasitic nematode Haemonchus contortus. Biochemical and biophysical research communications 254, 529-534.
13. Gant, D.B., Chalmers, A.E., Wolff, M.A., Hoffman, H.B., Bushey, D.F., 1998. Fipronil: action at the GABA Receptor. Reviews in Toxicology 2, 147-156.
14. Hainzl, D., Casida, J.E., 1996. Fipronil insecticide: novel photochemical desulfinylation with retention of neurotoxicity. Proceedings of the National Academy of Sciences of the United States of America 93, 12764-12767.
15. Hainzl, D., Cole, L.M., Casida, J.E., 1998. Mechanisms for selective toxicity of fipronil insecticide and its sulfone metabolite and desulfinyl photoproduct. Chemical Research in Toxicology 11, 1529-1535.
16. Horoszok, L., Raymond, V., Sattelle, D.B., Wolstenholme, A.J., 2001. GLC-3: a novel fipronil and BIDN-sensitive, but picrotoxinin-insensitive, L-glutamate-gated chloride channel subunit from Caenorhabditis elegans. British Journal of Pharmacology 132, 1247-1254.
17. Jackson, M.B., 1999. Ligand-gated channel: postsynaptic receptors and drug targets. Advances in Neurology 79, 511-524.
18. Jongejan, F.a.G.U., 1994. Ticks and control methods. Revue scientifique et technique International Office of Epizootics 13, 1201-1226.
19. Kane, N.S., Hirschberg, B., Qian, S., Hunt, D., Thomas, B., Brochu, R., Ludmerer, S.W., Zheng, Y., Smith, M., Arena, J.P., Cohen, C.J., Schmatz, D., Warmke, J., Cully, D.F., 2000. Drug-resistant Drosophila indicate glutamate-gated chloride channels are targets for the antiparasitics nodulisporic acid and ivermectin. Proceedings of the National Academy of Sciences of the United States of America 97, 13949-13954.
20. Kettle, D.S., 1984. Medical and Veterinary Entomology. In:. Croom Helm Ltd., London, 484.
21. Kirkwood, A.C., Quick, M.P., 1978. The efficacy of showers for control of ectoparasites of sheep. The Veterinary Record 102, 50-54.
22. Kunz, S.E., Kemp, D.H., 1994. Insecticides and acaricides: resistance and environmental impact. Revue scientifique et technique International Office of Epizootics 13, 1249-1286.
23. Nolan, J., 1990. Acaricide resistance in single and multi-host ticks and strategies for control. Parassitologoia 32, 145-153.
24. Paddock, C.D., Greer, P.W., Ferebee, T.L., Singleton, J., McKechnie, D.B., Treadwell, T.A., Krebs, J.W., Clark, M.J., Holman, R.C., Olson, J.G., Childs, J.E., Zaki, S.R., 1999. Hidden mortality attributable to rocky mountain spotted fever: immunohistochemical detection of fatal, serologically unconfirmed disease. Journal of Infectious Diseases 179, 1469-1476.
25. Strickland, R.K., Gerrish, R.R., Hourrigan, J.L., Czech, F.P., 1970. Chloropyridyl phosphorothioate insecticide as dip and spray: efficacy against Psoroptes ovis, dermal toxicity for domesticated animals, selective carryout, and stability in the dipping vat. American Journal of Veterinary Research 31, 2135-2143.
26. Thompson, M., Shotkoski, F., ffrench-Constant, R., 1993. Cloning and sequencing of the cyclodiene insecticide resistance gene from the yellow fever mosquito Aedes aegypti. Conservation of the gene and resistance associated mutation with Drosophila. FEBS Letters 325, 187-190.
27. Vassilatis, D.K., Elliston, K.O., Paress, P.S., Hamelin, M., Arena, J.P., Schaeffer, J.M., Van der Ploeg, L.H., Cully, D.F., 1997. Evolutionary relationship of the ligand-gated ion channels and the avermectin-sensitive, glutamate-gated chloride channels. Journal of Molecular Evolution 44, 501-508.
28. Wolff, M.A., Wingate, V.P., 1998. Characterization and comparative pharmacological studies of a functional gamma-aminobutyric acid (GABA) receptor cloned from the tobacco budworm, Heliothis virescens (Noctuidae:Lepidoptera). Invertebrate Neuroscience IN 3, 305-315.
29. Zhang, H.-G., ffrench-Constant, R.H., Jackson, M.B., 1994. A unique amino acid of the Drosophila GABA receptor with influence on drug sensitivity by two mechanisms. Journal of Physiology 479 (I), 65-75.
30. Zhang, H.-G., Lee, H.-J., Rocheleau, T., ffrench-Constant, R.H., Jackson, M.B., 1995. Subunit composition determines picrotoxin and bicuculline sensitivity of Drosophila γ-Aminobutyric acid receptors. Molecular Pharmacology 48, 835-840.