Inhibition of tau aggregation by three aspergillus nidulans secondary metabolites: 2, ω -dihydroxyemodin, asperthecin, and asperbenzaldehyde

Planta Medica

Volumn 80, Issue 1, 2014, Pages 77-85

  Paranjape, Smita R ^a   Chiang, Yi Ming ^b,c   Sanchez, James F ^b   Entwistle, Ruth ^a   Wang, Clay C C ^b   Oakley, Berl R ^a   Gamblin, T Chris ^a  

^a UNIVERSITY OF KANSAS   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c CHIA NAN UNIVERSITY OF PHARMACY AND SCIENCE   (Taiwan)

Author keywords

Alzheimer's disease; Aspergillus nidulans; microtubule associated protein; tau; Trichocomaceae

Indexed keywords

2 OMEGA DIHYDROXYEMODIN; ARACHIDONIC ACID; ASPERBENZALDEHYDE; ASPERTHECIN; EMODIN; HEPARIN; PROTEIN INHIBITOR; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ARTICLE; CONTROLLED STUDY; ELECTRON MICROSCOPY; EMERICELLA NIDULANS; FUNGAL METABOLISM; IC 50; IN VITRO STUDY; MICROTUBULE; NONHUMAN; POLYMERIZATION; PROTEIN AGGREGATION; TELOMERIC REPEAT AMPLIFICATION PROTOCOL;

ANTHRAQUINONES; ASPERGILLUS NIDULANS; BENZALDEHYDES; DRUG EVALUATION, PRECLINICAL; EMODIN; INHIBITORY CONCENTRATION 50; MICROTUBULES; MOLECULAR STRUCTURE; SECONDARY METABOLISM; TAU PROTEINS;

EID: 84892413120     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0033-1360180     Document Type: Article

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