The wobbler mouse model of amyotrophic lateral sclerosis (ALS) displays hippocampal hyperexcitability, and reduced number of interneurons, but no presynaptic vesicle release impairments

PLoS ONE

Volumn 8, Issue 12, 2013, Pages

  Thielsen, Karina D ^a   Moser, Jakob M ^a   Schmitt John, Thomas ^a   Jensen, Morten S ^a   Jensen, Kimmo ^a   Holm, Mai Marie ^a  

^a AARHUS UNIVERSITY   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTAMATE RECEPTOR; PARVALBUMIN;

ACTION POTENTIAL; AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CONTROLLED STUDY; EXCITATORY POSTSYNAPTIC POTENTIAL; FACILITATION; FEMALE; HIPPOCAMPAL CA1 REGION; HIPPOCAMPAL HYPEREXCITABILITY; INTERNEURON; MALE; MOTOR CORTEX; MOUSE; NERVE CELL NETWORK; NERVE EXCITABILITY; NERVE FIBER TRANSPORT; NEUROTRANSMITTER RELEASE; NONHUMAN; PAIRED PULSE FACILITATION; PRESYNAPTIC VESICLE RELEASE IMPAIRMENT; PYRAMIDAL NERVE CELL; SYNAPTIC TRANSMISSION;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; DISEASE MODELS, ANIMAL; HIPPOCAMPUS; INTERNEURONS; MICE; PRESYNAPTIC TERMINALS; PYRAMIDAL CELLS; SYNAPTIC POTENTIALS;

EID: 84892412069     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0082767     Document Type: Article

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