Loss of Vps54 function leads to vesicle traffic impairment, protein mis-sorting and embryonic lethality

International Journal of Molecular Sciences

Volumn 14, Issue 6, 2013, Pages 10908-10925

  Karlsson, Páll ^a   Droce, Aida ^a,d   Moser, Jakob M ^a   Cuhlmann, Simon ^a   Padilla, Carolina Ortiz ^a   Heimann, Peter ^b   Bartsch, Jörg W ^c   Füchtbauer, Annette ^a   Füchtbauer, Ernst Martin ^a   Schmitt John, Thomas ^a  

^a AARHUS UNIVERSITY   (Denmark)

^b BIELEFELD UNIVERSITY   (Germany)

^c PHILIPPS UNIVERSITY MARBURG   (Germany)

^d AALBORG UNIVERSITY   (Denmark)

Author keywords

ALS; GARP complex; Retrograde vesicle transport; Vps54; Wobbler

Indexed keywords

CARRIER PROTEIN; CELL PROTEIN; CHOLERA TOXIN B SUBUNIT; PROTEIN VPS54; SOMATOMEDIN B RECEPTOR; UNCLASSIFIED DRUG; CATHEPSIN B; CHOLERA TOXIN; VESICULAR TRANSPORT PROTEIN; VPS54 PROTEIN, MOUSE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ARTICLE; CELL MUTANT; CELL TRANSPORT; CELL VACUOLE; CONTROLLED STUDY; EMBRYO; ENDOCYTOSIS; FIBROBLAST CULTURE; HUMAN; HUMAN CELL; HUMAN TISSUE; LETHALITY; LOSS OF FUNCTION MUTATION; MOUSE; NONHUMAN; NULL ALLELE; PROTEIN FUNCTION; PROTEIN MISSORTING; PROTEIN TARGETING; SKIN FIBROBLAST; TRANS GOLGI NETWORK; WILD TYPE; ANIMAL; ANIMAL EMBRYO; C57BL MOUSE; CELL MEMBRANE; DEFICIENCY; EMBRYO DEATH; FIBROBLAST; GENETICS; KNOCKOUT MOUSE; METABOLISM; MUTATION; PATHOLOGY; PROTEIN TRANSPORT; SKIN; TRANSPORT VESICLE; ULTRASTRUCTURE; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CATHEPSIN B; CELL MEMBRANE; CHOLERA TOXIN; EMBRYO LOSS; EMBRYO, MAMMALIAN; ENDOCYTOSIS; FIBROBLASTS; HUMANS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUTATION; PROTEIN TRANSPORT; RECEPTOR, IGF TYPE 2; SKIN; TRANSPORT VESICLES; VESICULAR TRANSPORT PROTEINS;

EID: 84878461559     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms140610908     Document Type: Article

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