Neural precursor-derived astrocytes of wobbler mice induce apoptotic death of motor neurons through reduced glutamate uptake

Experimental Neurology

Volumn 225, Issue 1, 2010, Pages 163-172

  Diana, Valentina ^a   Ottolina, Arianna ^a   Botti, Francesca ^b   Fumagalli, Elena ^a   Calcagno, Eleonora ^a   De Paola, Massimiliano ^a   Cagnotto, Alfredo ^a   Invernici, Gloria ^c   Parati, Eugenio ^c   Curti, Daniela ^b   Mennini, Tiziana ^a  

^a MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^b UNIVERSITY OF PAVIA   (Italy)

^c DEPARTMENT OF NEUROSURGERY   (Italy)

Author keywords

Excitotoxicity; Glutamate transporters; Motor neuron disease; Stem cell; Uptake

Indexed keywords

CASPASE 7; EXCITATORY AMINO ACID TRANSPORTER; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUTAMIC ACID; VESICULAR GLUTAMATE TRANSPORTER 1;

ANIMAL CELL; APOPTOSIS; ARTICLE; ASTROCYTE; CELL STRUCTURE; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; EMBRYO; IN VITRO STUDY; MOUSE; NERVE CELL CULTURE; NERVE DEGENERATION; NEURAL STEM CELL; NONHUMAN; PRIORITY JOURNAL; SPINAL CORD MOTONEURON; SUBVENTRICULAR ZONE; ANIMAL; CELL COMMUNICATION; CELL CULTURE; CELL DEATH; COCULTURE; METABOLISM; MOTONEURON; MOUSE MUTANT; PATHOLOGY; PHYSIOLOGY; STEM CELL;

ANIMALS; APOPTOSIS; ASTROCYTES; CELL COMMUNICATION; CELL DEATH; CELLS, CULTURED; COCULTURE TECHNIQUES; GLUTAMIC ACID; MICE; MICE, NEUROLOGIC MUTANTS; MOTOR NEURONS; NERVE DEGENERATION; STEM CELLS;

EID: 77955661910     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2010.06.008     Document Type: Article

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