Pulmonary artery smooth muscle cell proliferation and migration in fetal lambs acclimatized to high-altitude long-term hypoxia: Role of histone acetylation

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 303, Issue 11, 2012, Pages

  Yang, Qiwei ^a   Lu, Ziyan ^a   Ramchandran, Ramaswamy ^a   Longo, Lawrence D ^b   Usha Raj, J ^a,c  

^a UNIVERSITY OF ILLINOIS   (United States)

^b LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF ILLINOIS HOSPITAL AND HEALTH SCIENCES SYSTEM   (United States)

Author keywords

Epigenetics; High altitude long term hypoxia; Histone deacetylase; p21; PDGF

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1A; HISTONE DEACETYLASE; HISTONE H4; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; RNA; TRICHOSTATIN A;

ALTITUDE; ANIMAL CELL; ARTICLE; CELL CYCLE ARREST; CELL CYCLE PROGRESSION; CELL HYPOXIA; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DNA METHYLATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; EPIGENETICS; FEMALE; FETUS; HISTONE ACETYLATION; LAMB; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PULMONARY ARTERY; SMOOTH MUSCLE FIBER;

ACCLIMATIZATION; ACETYLATION; ALTITUDE; ANIMALS; CELL CYCLE CHECKPOINTS; CELL MOVEMENT; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DNA METHYLATION; EPIGENESIS, GENETIC; FEMALE; FETAL HYPOXIA; FETUS; GENE EXPRESSION; HISTONE DEACETYLASE INHIBITORS; HISTONES; HYDROXAMIC ACIDS; MAP KINASE SIGNALING SYSTEM; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PEPTIDES, CYCLIC; PLATELET-DERIVED GROWTH FACTOR; PREGNANCY; PROTEIN PROCESSING, POST-TRANSLATIONAL; PULMONARY ARTERY; SHEEP; TIME FACTORS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84870915628     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00092.2012     Document Type: Article

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