-
1
-
-
2342590065
-
The global burden of asthma: Executive summary of the GINA Dissemination Committee Report
-
DOI 10.1111/j.1398-9995.2004.00526.x
-
Masoli M, Fabian D, Holt ST, et al. The global burden of asthma: executive summary of the GINA Dissemination Committee report. Allergy 2004;59:469-78. (Pubitemid 38580764)
-
(2004)
Allergy: European Journal of Allergy and Clinical Immunology
, vol.59
, Issue.5
, pp. 469-478
-
-
Masoli, M.1
Fabian, D.2
Holt, S.3
Beasley, R.4
-
2
-
-
0028079557
-
Steroid-resistant asthma: Cellular mechanisms contributing to inadequate response to glucocorticoid therapy
-
Sher ER, Leung DY, Surs W, et al. Steroid-resistant asthma: cellular mechanisms contributing to inadequate response to glucocorticoid therapy. J Clin Invest 1994;93:33-9.
-
(1994)
J Clin Invest
, vol.93
, pp. 33-39
-
-
Sher, E.R.1
Leung, D.Y.2
Surs, W.3
-
3
-
-
0032914288
-
Increased glucocorticoid receptor beta in airway cells of glucocorticoid- insensitive asthma
-
Hamid QA, Wenzel SE, Hauk PJ, et al. Increased glucocorticoid receptor beta in airway cells of glucocorticoid-insensitive asthma. Am J Respir Crit Care Med 1999;159:1600-4. (Pubitemid 29227876)
-
(1999)
American Journal of Respiratory and Critical Care Medicine
, vol.159
, Issue.5 I
, pp. 1600-1604
-
-
Hamid, Q.A.1
Wenzel, S.E.2
Hauk, P.J.3
Tsicopoulos, A.4
Wallaert, B.5
Lafitte, J.-J.6
Chrousos, G.P.7
Szefler, S.J.8
Leung, D.Y.M.9
-
4
-
-
0031018474
-
Allergen exposure decreases glucocorticoid receptor binding affinity and steroid responsiveness in atopic asthmatics
-
Nimmagadda SR, Szefler SJ, Spahn JD, et al. Allergen exposure decreases glucocorticoid receptor binding affinity and steroid responsiveness in atopic asthmatics. Am J Respir Crit Care Med 1997;155:87-93. (Pubitemid 27053146)
-
(1997)
American Journal of Respiratory and Critical Care Medicine
, vol.155
, Issue.1
, pp. 87-93
-
-
Nimmagadda, S.R.1
Szefler, S.J.2
Spahn, J.D.3
Surs, W.4
Leung, D.Y.M.5
-
6
-
-
2342567291
-
Defective glucocorticoid receptor nuclear translocation and altered histone acetylation patterns in glucocorticoid-resistant patients
-
DOI 10.1016/j.jaci.2004.03.018, PII S0091674904011509
-
Matthews JG, Ito K, Barnes PJ, et al. Defective glucocorticoid receptor nuclear translocation and altered histone acetylation patterns in glucocorticoid-resistant patients. J Allergy Clin Immunol 2004;113:1100-8. (Pubitemid 38857992)
-
(2004)
Journal of Allergy and Clinical Immunology
, vol.113
, Issue.6
, pp. 1100-1108
-
-
Matthews, J.G.1
Ito, K.2
Barnes, P.J.3
Adcock, I.M.4
-
7
-
-
0028881859
-
Abnormal glucocorticoid receptor-activator protein 1 interaction in steroid-resistant asthma
-
Adcock IM, Lane SJ, Brown CR, et al. Abnormal glucocorticoid receptor-activator protein 1 interaction in steroid-resistant asthma. J Exp Med 1995;182:1951-8.
-
(1995)
J Exp Med
, vol.182
, pp. 1951-1958
-
-
Adcock, I.M.1
Lane, S.J.2
Brown, C.R.3
-
8
-
-
49449089908
-
Molecular mechanisms of corticosteroid resistance
-
Adcock IM, Barnes PJ. Molecular mechanisms of corticosteroid resistance. Chest 2008;134:394-401.
-
(2008)
Chest
, vol.134
, pp. 394-401
-
-
Adcock, I.M.1
Barnes, P.J.2
-
9
-
-
31344446119
-
Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF-kappaB suppression
-
DOI 10.1084/jem.20050466
-
Ito K, Yamamura S, Essilfie-Quaye S, et al. Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF-{kappa}B suppression. J Exp Med 2006;203:7-13. (Pubitemid 43139638)
-
(2006)
Journal of Experimental Medicine
, vol.203
, Issue.1
, pp. 7-13
-
-
Ito, K.1
Yamamura, S.2
Essilfie-Quaye, S.3
Cosio, B.4
Ito, M.5
Barnes, P.J.6
Adcock, I.M.7
-
10
-
-
77958165660
-
Inhibition of histone deacetylase 2 expression by elevated glucocorticoid receptor beta in steroid-resistant asthma
-
Li LB, Leung DY, Martin RJ, et al. Inhibition of histone deacetylase 2 expression by elevated glucocorticoid receptor beta in steroid-resistant asthma. Am J Respir Crit Care Med 2010;182:877-83.
-
(2010)
Am J Respir Crit Care Med
, vol.182
, pp. 877-883
-
-
Li, L.B.1
Leung, D.Y.2
Martin, R.J.3
-
11
-
-
0030702823
-
Association of glucocorticoid insensitivity with increased expression of glucocorticoid receptor beta
-
DOI 10.1084/jem.186.9.1567
-
Leung DY, Hamid Q, Vottero A, et al. Association of glucocorticoid insensitivity with increased expression of glucocorticoid receptor beta. J Exp Med 1997;186:1567-74. (Pubitemid 27479816)
-
(1997)
Journal of Experimental Medicine
, vol.186
, Issue.9
, pp. 1567-1574
-
-
Leung, D.Y.M.1
Hamid, Q.2
Vottero, A.3
Szefler, S.J.4
Surs, W.5
Minshall, E.6
Chrousos, G.P.7
Klemm, D.J.8
-
12
-
-
33644834415
-
Increased glucocorticoid receptor beta alters steroid response in glucocorticoid-insensitive asthma
-
DOI 10.1164/rccm.200507-1046OC
-
Goleva E, Li LB, Eves PT, et al. Increased glucocorticoid receptor beta alters steroid response in glucocorticoid-insensitive asthma. Am J Respir Crit Care Med 2006;173:607-16. (Pubitemid 43363801)
-
(2006)
American Journal of Respiratory and Critical Care Medicine
, vol.173
, Issue.6
, pp. 607-616
-
-
Goleva, E.1
Li, L.-B.2
Eves, P.T.3
Strand, M.J.4
Martin, R.J.5
Leung, D.Y.M.6
-
13
-
-
0004815929
-
Glucocorticoid resistance in asthma is associated with elevated in vivo expression of the glucocorticoid receptor beta-isoform
-
Sousa AR, Lane SJ, Cidlowski JA, et al. Glucocorticoid resistance in asthma is associated with elevated in vivo expression of the glucocorticoid receptor beta-isoform. J Allergy Clin Immunol 2000;105:943-50. (Pubitemid 30324403)
-
(2000)
Journal of Allergy and Clinical Immunology
, vol.105
, Issue.5
, pp. 943-950
-
-
Sousa, A.R.1
Lane, S.J.2
Cidlowski, J.A.3
Staynov, D.Z.4
Lee, T.H.5
-
14
-
-
0034502208
-
Increased number of glucocorticoid receptor-beta-expressing cells in the airways in fatal asthma
-
DOI 10.1067/mai.2000.109054
-
Christodoulopoulos P, Leung DY, Elliott MW, et al. Increased number of glucocorticoid receptor-beta-expressing cells in the airways in fatal asthma. J Allergy Clin Immunol 2000;106:479-84. (Pubitemid 32037700)
-
(2000)
Journal of Allergy and Clinical Immunology
, vol.106
, Issue.3
, pp. 479-484
-
-
Christodoulopoulos, P.1
Leung, D.Y.M.2
Elliott, M.W.3
Hogg, J.C.4
Muro, S.5
Toda, M.6
Laberge, S.7
Hamid, Q.A.8
-
15
-
-
33644777427
-
Increased glucocorticoid receptor-beta expression, but not decreased histone deacetylase 2, in severe asthma [1]
-
DOI 10.1016/j.jaci.2005.12.1344, PII S0091674906000066
-
Bergeron CB, Fukakusa M, Olivenstein R, et al. Increased glucocorticoid receptor-β expression, but not decreased histone deacetylase 2, in severe asthma. J Allergy Clin Immunol 2006;117:703-5. (Pubitemid 43340239)
-
(2006)
Journal of Allergy and Clinical Immunology
, vol.117
, Issue.3
, pp. 703-705
-
-
Bergeron, C.1
Fukakusa, M.2
Olivenstein, R.3
Lemiere, C.4
Shannon, J.5
Ernst, P.6
Martin, J.G.7
Hamid, Q.8
-
16
-
-
0033930349
-
Glucocorticoid receptor alpha and beta in glucocorticoid dependent asthma
-
Gagliardo R, Chanez P, Vignola AM, et al. Glucocorticoid receptor alpha and beta in glucocorticoid dependent asthma. Am J Respir Crit Care Med 2000;162:7-13. (Pubitemid 30469790)
-
(2000)
American Journal of Respiratory and Critical Care Medicine
, vol.162
, Issue.1
, pp. 7-13
-
-
Gagliardo, R.1
Chanez, P.2
Vignola, A.M.3
Bousquet, J.4
Vachier, I.5
Godard, P.6
Bonsignore, G.7
Demoly, P.8
Mathieu, M.9
-
17
-
-
4544387162
-
Glucocorticoid receptor isoforms alpha and beta in in vitro cytokine-induced glucocorticoid insensitivity
-
DOI 10.1164/rccm.200308-1143OC
-
Torrego A, Pujols L, Roca-Ferrer J, et al. Glucocorticoid receptor isoforms alpha and beta in in vitro cytokine-induced glucocorticoid insensitivity. Am J Respir Crit Care Med 2004;170:420-5. (Pubitemid 39214617)
-
(2004)
American Journal of Respiratory and Critical Care Medicine
, vol.170
, Issue.4
, pp. 420-425
-
-
Torrego, A.1
Pujols, L.2
Roca-Ferrer, J.3
Mullol, J.4
Xaubet, A.5
Picado, C.6
-
18
-
-
0034526865
-
Current understanding, recommendations, and unanswered questions
-
Anon. Proceedings of the ATS Workshop on Refractory Asthma
-
Anon. Proceedings of the ATS Workshop on Refractory Asthma. Current understanding, recommendations, and unanswered questions. Am J Respir Crit Care Med 2000;162:2341-51.
-
(2000)
Am J Respir Crit Care Med
, vol.162
, pp. 2341-2351
-
-
-
19
-
-
39049170984
-
Global strategy for asthma management and prevention GINA executive summary
-
Bateman ED, Hurd SS, Barnes PJ, et al. Global strategy for asthma management and prevention GINA executive summary. Eur Respir J 2008;31:143-78.
-
(2008)
Eur Respir J
, vol.31
, pp. 143-178
-
-
Bateman, E.D.1
Hurd, S.S.2
Barnes, P.J.3
-
20
-
-
0035710746
-
-DeltaDeltaCT method
-
DOI 10.1006/meth.2001.1262
-
Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 2001; 25:402-8. (Pubitemid 34164012)
-
(2001)
Methods
, vol.25
, Issue.4
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
21
-
-
0027358764
-
Immunohistochemistry on resin sections: A comparison of resin embedding techniques for small mucosal biopsies
-
Britten KM, Howarth PH, Roche WR. Immunohistochemistry on resin sections: a comparison of resin embedding techniques for small mucosal biopsies. Biotech Histochem 1993;68:271-80. (Pubitemid 23305102)
-
(1993)
Biotechnic and Histochemistry
, vol.68
, Issue.5
, pp. 271-280
-
-
Britten, K.M.1
Howarth, P.H.2
Roche, W.R.3
-
22
-
-
66749097651
-
Repression of TNF-alpha-induced IL-8 expression by the glucocorticoid receptor-beta involves inhibition of histone H4 acetylation
-
Kim SH, Kim DH, Lavender P, et al. Repression of TNF-alpha-induced IL-8 expression by the glucocorticoid receptor-beta involves inhibition of histone H4 acetylation. Exp Mol Med 2009;41:297-306.
-
(2009)
Exp Mol Med
, vol.41
, pp. 297-306
-
-
Kim, S.H.1
Kim, D.H.2
Lavender, P.3
-
23
-
-
0029807036
-
The non-ligand binding beta-isoform of the human glucocorticoid receptor (hGRbeta): Tissue levels, mechanism of action, and potential physiologic role
-
de Castro M, Elliot S, Kino T, et al. The non-ligand binding beta-isoform of the human glucocorticoid receptor (hGR beta): tissue levels, mechanism of action and potential physiologic role. Mol Med 1996;2:597-607. (Pubitemid 26353108)
-
(1996)
Molecular Medicine
, vol.2
, Issue.5
, pp. 597-607
-
-
De Castro, M.1
Elliot, S.2
Kino, T.3
Bamberger, C.4
Karl, M.5
Webster, E.6
Chrousos, G.P.7
-
24
-
-
0032878703
-
Clathrin: Anatomy of a coat protein
-
DOI 10.1016/S0962-8924(99)01631-1
-
Smith CJ, Pearse BM. Clathrin: anatomy of a coat protein. Trends Cell Biol 1999;9:335-8. (Pubitemid 29447712)
-
(1999)
Trends in Cell Biology
, vol.9
, Issue.9
, pp. 335-338
-
-
Smith, C.J.1
Pearse, B.M.F.2
-
25
-
-
0030702823
-
Association of glucocorticoid insensitivity with increased expression of glucocorticoid receptor beta
-
DOI 10.1084/jem.186.9.1567
-
Leung DY, Hamid Q, Vottero A, et al. Association of glucocorticoid insensitivity with increased expression of glucocorticoid receptor beta. J Exp Med 1997;186:1567-74. (Pubitemid 27479816)
-
(1997)
Journal of Experimental Medicine
, vol.186
, Issue.9
, pp. 1567-1574
-
-
Leung, D.Y.M.1
Hamid, Q.2
Vottero, A.3
Szefler, S.J.4
Surs, W.5
Minshall, E.6
Chrousos, G.P.7
Klemm, D.J.8
-
26
-
-
34548127056
-
Glucocorticoid receptor isoform expression does not predict steroid treatment response in IBD [12]
-
DOI 10.1136/gut.2006.108035
-
Hausmann M, Herfarth H, Scholmerich J, et al. Glucocorticoid receptor isoform expression does not predict steroid treatment response in IBD. Gut 2007;56:1328-9. (Pubitemid 47300447)
-
(2007)
Gut
, vol.56
, Issue.9
, pp. 1328-1329
-
-
Hausmann, M.1
Herfarth, H.2
Scholmerich, J.3
Rogler, G.4
-
27
-
-
0034058875
-
Expression of glucocorticoid receptor beta in lymphocytes of patients with glucocorticoid-resistant ulcerative colitis
-
Honda M, Orii F, Ayabe T, et al. Expression of glucocorticoid receptor beta in lymphocytes of patients with glucocorticoid-resistant ulcerative colitis. Gastroenterology 2000;118:859-66. (Pubitemid 30243749)
-
(2000)
Gastroenterology
, vol.118
, Issue.5
, pp. 859-866
-
-
Honda, M.1
Orii, F.2
Ayabe, T.3
Imai, S.4
Ashida, T.5
Obara, T.6
Kohgo, Y.7
-
28
-
-
34047123776
-
The differential expression of corticosteroid receptor isoforms in corticosteroid-resistant and -sensitive patients with rheumatoid arthritis
-
DOI 10.1093/rheumatology/kel276
-
Kozaci DL, Chernajovsky Y, Chikanza IC. The differential expression of corticosteroid receptor isoforms in corticosteroid-resistant and -sensitive patients with rheumatoid arthritis. Rheumatology (Oxford) 2007;46:579-85. (Pubitemid 46523299)
-
(2007)
Rheumatology
, vol.46
, Issue.4
, pp. 579-585
-
-
Kozaci, D.L.1
Chernajovsky, Y.2
Chikanza, I.C.3
-
29
-
-
0036392066
-
Quantitative analysis for human glucocorticoid receptor [alpha]/[beta] mRNA in IBD
-
Orii F, Ashida T, Nomura M, et al. Quantitative analysis for human glucocorticoid receptor [alpha]/[beta] mRNA in IBD. Biochem Biophys Res Commun 2002;296:1286-94.
-
(2002)
Biochem Biophys Res Commun
, vol.296
, pp. 1286-1294
-
-
Orii, F.1
Ashida, T.2
Nomura, M.3
-
30
-
-
33644811218
-
Regulation of glucocorticoid responsiveness in glaucomatous trabecular meshwork cells by glucocorticoid receptor-beta
-
DOI 10.1167/iovs.05-0571
-
Zhang X, Clark AF, Yorio T. Regulation of glucocorticoid responsiveness in glaucomatous trabecular meshwork cells by glucocorticoid receptor-β. Invest Ophthalmol Vis Sci 2005;46:4607-16. (Pubitemid 44264561)
-
(2005)
Investigative Ophthalmology and Visual Science
, vol.46
, Issue.12
, pp. 4607-4616
-
-
Zhang, X.1
Clark, A.F.2
Yorio, T.3
-
31
-
-
77952742460
-
Overexpression of glucocorticoid receptor-β in severe allergic rhinitis
-
Ishida A, Ohta N, Koike S, et al. Overexpression of glucocorticoid receptor-β in severe allergic rhinitis. Auris Nasus Larynx 2010;37:584-8.
-
(2010)
Auris Nasus Larynx
, vol.37
, pp. 584-588
-
-
Ishida, A.1
Ohta, N.2
Koike, S.3
-
32
-
-
21044458874
-
Decreased histone deacetylase activity in chronic obstructive pulmonary disease
-
DOI 10.1056/NEJMoa041892
-
Ito K, Ito M, Elliott WM, et al. Decreased histone deacetylase activity in chronic obstructive pulmonary disease. N Engl J Med 2005;352:1967-76. (Pubitemid 40638367)
-
(2005)
New England Journal of Medicine
, vol.352
, Issue.19
, pp. 1967-1976
-
-
Ito, K.1
Ito, M.2
Elliott, W.M.3
Cosio, B.4
Caramori, G.5
Onn, M.K.6
Barczyk, A.7
Hayashi, S.8
Adcock, I.M.9
Hogg, J.C.10
Barnes, P.J.11
-
33
-
-
0035315925
-
Cigarette smoking reduces histone deacetylase 2 expression, enhances cytokine expression, and inhibits glucocorticoid actions in alveolar macrophages
-
Ito K, Lim S, Caramori G, et al. Cigarette smoking reduces histone deacetylase 2 expression, enhances cytokine expression, and inhibits glucocorticoid actions in alveolar macrophages. FASEB J 2001;15:1110-12.
-
(2001)
FASEB J
, vol.15
, pp. 1110-1112
-
-
Ito, K.1
Lim, S.2
Caramori, G.3
-
34
-
-
0036683630
-
Expression and activity of histone deacetylases in human asthmatic airways
-
DOI 10.1164/rccm.2110060
-
Ito K, Caramori G, Lim S, et al. Expression and activity of histone deacetylases in human asthmatic airways. Am J Respir Crit Care Med 2002;166:392-6. (Pubitemid 34864433)
-
(2002)
American Journal of Respiratory and Critical Care Medicine
, vol.166
, Issue.3
, pp. 392-396
-
-
Ito, K.1
Caramori, G.2
Lim, S.3
Oates, T.4
Fan, C.K.5
Barnes, P.J.6
Adcock, I.M.7
-
35
-
-
3142676314
-
Histone acetylase and deacetylase activity in alveolar macrophages and blood mononocytes in asthma
-
Cosio BG, Mann B, Ito K, et al. Histone acetylase and deacetylase activity in alveolar macrophages and blood mononocytes in asthma. Am J Respir Crit Care Med 2004;170:141-7. (Pubitemid 38925159)
-
(2004)
American Journal of Respiratory and Critical Care Medicine
, vol.170
, Issue.2
, pp. 141-147
-
-
Cosio, B.G.1
Mann, B.2
Ito, K.3
Jazrawi, E.4
Barnes, P.J.5
Chung, K.F.6
Adcock, I.M.7
-
36
-
-
4544379912
-
Theophylline restores histone deacetylase activity and steroid responses in COPD macrophages
-
DOI 10.1084/jem.20040416
-
Cosio BG, Tsaprouni L, Ito K, et al. Theophylline restores histone deacetylase activity and steroid responses in COPD macrophages. J Exp Med 2004;200:689-95. (Pubitemid 39258317)
-
(2004)
Journal of Experimental Medicine
, vol.200
, Issue.5
, pp. 689-695
-
-
Cosio, B.G.1
Tsaprouni, L.2
Ito, K.3
Jazrawi, E.4
Adcock, I.M.5
Barnes, P.J.6
-
37
-
-
0037173056
-
A molecular mechanism of action of theophylline: Induction of histone deacetylase activity to decrease inflammatory gene expression
-
DOI 10.1073/pnas.132556899
-
Ito K, Lim S, Caramori G, et al. A molecular mechanism of action of theophylline: induction of histone deacetylase activity to decrease inflammatory gene expression. Proc Natl Acad Sci U S A 2002;99:8921-6. (Pubitemid 34693659)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.13
, pp. 8921-8926
-
-
Ito, K.1
Lim, S.2
Caramori, G.3
Cosio, B.4
Chung, K.F.5
Adcock, I.M.6
Barnes, P.J.7
|