Pharmacologic IKK/NF-kappa;B inhibition causes antigen presenting cells to undergo TNFα dependent ROS-mediated programmed cell death

Scientific Reports

Volumn 4, Issue , 2014, Pages

  Tilstra, Jeremy S ^a   Gaddy, Daniel F ^a   Zhao, Jing ^a,d   Davé, Shaival H ^a   Niedernhofer, Laura J ^a,c,d   Plevy, Scott E ^b   Robbins, Paul D ^a,d  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^d SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 8; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL; ANTIGEN PRESENTING CELL; APOPTOSIS; ARTICLE; CELL LINE; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; ENZYME ACTIVATION; MACROPHAGE; METABOLISM; MOUSE; PHYSIOLOGY;

ANIMALS; ANTIGEN-PRESENTING CELLS; APOPTOSIS; CASPASE 8; CELL LINE; ENZYME ACTIVATION; I-KAPPA B KINASE; MACROPHAGES; MAP KINASE KINASE 4; MICE; NF-KAPPA B; REACTIVE OXYGEN SPECIES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84892146352     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep03631     Document Type: Article

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