NF-κB inhibition triggers death of imatinib-sensitive and imatinib-resistant chronic myeloid leukemia cells including T315I Bcr-Abl mutants

International Journal of Cancer

Volumn 125, Issue 2, 2009, Pages 308-317

  Lounnas, Nadia ^a,b   Frelin, Catherine ^a,b   Gonthier, Nadège ^a,b   Colosetti, Pascal ^a,b   Sirvent, Anne ^c   Cassuto, Jil Patrice ^c   Berthier, Fréderic ^d   Sirvent, Nicolas ^c   Rousselot, Philippe ^e   Dreano, Michel ^f   Peyron, Jean François ^a,b,c   Imbert, Véronique ^a,b  

^a CENTRE MÉDITERRANÉEN DE MÉDECINE MOLÉCULAIRE C3M   (France)

^b UNIVERSITÉ CÔTE D'AZUR   (France)

^c CENTRE HOSPITALIER UNIVERSITAIRE DE NICE   (France)

^d University of Côte d'Azur   (France)

^e CENTRE HOSPITALIER DE VERSAILLES   (France)

^f MERCK SERONO S A   (Switzerland)

Author keywords

Bcr Abl; CML; NF kappaB; T315I mutant

Indexed keywords

1 [5 HYDROXY 2 (2 THIENYL) 4 QUINAZOLINYLAMINO] 3 METHYL 2,5 PYRROLEDIONE; BCR ABL PROTEIN; IMATINIB; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; ANTINEOPLASTIC AGENT; PIPERAZINE DERIVATIVE; PYRIMIDINE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL DESTRUCTION; CANCER GROWTH; CANCER MODEL; CANCER RESISTANCE; CANCER SURVIVAL; CELL VIABILITY; CHEMOSENSITIVITY; CHRONIC MYELOID LEUKEMIA; COLONY FORMING UNIT; CONTROLLED STUDY; FEMALE; GENE MUTATION; GENE TARGETING; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LEUKEMIA CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; TRANSCRIPTION REGULATION; WILD TYPE; XENOGRAFT; ANIMAL; APOPTOSIS; DRUG ANTAGONISM; DRUG EFFECT; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; MUTATION; NUDE MOUSE; ONCOGENE; PATHOLOGY; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; FLUORESCENT ANTIBODY TECHNIQUE; GENES, ABL; HUMANS; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; MICE; MICE, NUDE; MUTATION; NF-KAPPA B; PIPERAZINES; PYRIMIDINES;

EID: 67449094298     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.24294     Document Type: Article

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