Induction of sestrin2 as an endogenous protective mechanism against amyloid beta-peptide neurotoxicity in primary cortical culture

Experimental Neurology

Volumn 253, Issue , 2014, Pages 63-71

  Chen, Yueh Sheng ^a   Chen, Shang Der ^b,c   Wu, Chia Lin ^a   Huang, Shiang Suo ^d,e   Yang, Ding I ^a  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^c CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^d CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^e CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Alzheimer's disease; Amyloid peptide; Autophagy; Bafilomycin A1; LC3B; Sestrins

Indexed keywords

AMYLOID BETA PROTEIN; BAFILOMYCIN A1; REGULATOR PROTEIN; SESTRIN2 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; BRAIN CORTEX; BRAIN NERVE CELL; BRAIN TOXICITY; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; FETUS; INHIBITION KINETICS; MOUSE; NERVE CELL NECROSIS; NEUROMODULATION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN INDUCTION; RAT; TRANSGENIC MOUSE; UPREGULATION;

ALZHEIMER'S DISEASE; AMYLOID Β-PEPTIDE; AUTOPHAGY; BAFILOMYCIN A1; LC3B; SESTRINS;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; BRAIN INJURIES; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; EMBRYO, MAMMALIAN; ENZYME INHIBITORS; GENE EXPRESSION REGULATION; HUMANS; MACROLIDES; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MICROTUBULE-ASSOCIATED PROTEINS; MUTATION; NUCLEAR PROTEINS; ORGAN CULTURE TECHNIQUES; PEPTIDE FRAGMENTS; PRESENILIN-1; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS;

EID: 84891905283     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2013.12.009     Document Type: Article

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