메뉴 건너뛰기




Volumn 14, Issue 1, 2014, Pages 45-57

DNA methylation and miRNAs regulation in hereditary breast cancer: Epigenetic changes, players in transcriptional and post-transcriptional regulation in hereditary breast cancer

Author keywords

Basal like breast cancer; BRCA1; Hereditary breast cancer; Methylation; miRNA; Triple negative breast cancer

Indexed keywords

ALKYLATING AGENT; BRCA1 PROTEIN; DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE 3B; MICRORNA; MICRORNA 100; MICRORNA 101; MICRORNA 10B; MICRORNA 125B; MICRORNA 130A; MICRORNA 143; MICRORNA 145; MICRORNA 17; MICRORNA 195; MICRORNA 205; MICRORNA 21; MICRORNA 300; MICRORNA 320A; MICRORNA 320B; MICRORNA 320C; MICRORNA 320D; MICRORNA 335; MICRORNA 499; MICRORNA 99A; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; PRE MICRORNA; RAS ASSOCIATION DOMAIN FAMILY PROTEIN 1A; TAMOXIFEN; UNCLASSIFIED DRUG; UNINDEXED DRUG; PROTEIN P53;

EID: 84891853034     PISSN: 15665240     EISSN: 18755666     Source Type: Journal    
DOI: 10.2174/1566524013666131203101405     Document Type: Review
Times cited : (18)

References (111)
  • 1
    • 0023279926 scopus 로고
    • The inheritance of epigenetic defects
    • Holliday R. The inheritance of epigenetic defects. Science 1987; 238(4824): 163-70.
    • (1987) Science , vol.238 , Issue.4824 , pp. 163-170
    • Holliday, R.1
  • 2
    • 77149135270 scopus 로고    scopus 로고
    • Breast cancer epigenetics: From DNA methylation to microRNAs
    • Veeck J, Esteller M. Breast cancer epigenetics: from DNA methylation to microRNAs. J Mammary Gland Biol Neoplasia 2010; 15(1): 5-17.
    • (2010) J Mammary Gland Biol Neoplasia , vol.15 , Issue.1 , pp. 5-17
    • Veeck, J.1    Esteller, M.2
  • 3
    • 0033153303 scopus 로고    scopus 로고
    • The human DNA methyltransferases (DNMTs) 1, 3a and 3b: Coordinate mRNA expression in normal tissues and overexpression in tumors
    • Robertson KD, Uzvolgyi E, Liang G, et al. The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors. Nucleic Acids Res 1999; 27(11): 2291-8.
    • (1999) Nucleic Acids Res , vol.27 , Issue.11 , pp. 2291-2298
    • Robertson, K.D.1    Uzvolgyi, E.2    Liang, G.3
  • 4
    • 0141995080 scopus 로고    scopus 로고
    • Expression analysis of DNA methyltransferases 1, 3A, and 3B in sporadic breast carcinomas
    • Girault I, Tozlu S, Lidereau R, Bieche I. Expression analysis of DNA methyltransferases 1, 3A, and 3B in sporadic breast carcinomas. Clin Cancer Res 2003; 9(12): 4415-22.
    • (2003) Clin Cancer Res , vol.9 , Issue.12 , pp. 4415-4422
    • Girault, I.1    Tozlu, S.2    Lidereau, R.3    Bieche, I.4
  • 5
    • 18244388241 scopus 로고    scopus 로고
    • DNA methylation patterns in hereditary human cancers mimic sporadic tumorigenesis
    • Esteller M, Fraga MF, Guo M, et al. DNA methylation patterns in hereditary human cancers mimic sporadic tumorigenesis. Hum Mol Genet 2001; 10(26): 3001-7.
    • (2001) Hum Mol Genet , vol.10 , Issue.26 , pp. 3001-3007
    • Esteller, M.1    Fraga, M.F.2    Guo, M.3
  • 6
    • 49249136904 scopus 로고    scopus 로고
    • Promoter hypermethylation of BRCA1 correlates with absence of expression in hereditary breast cancer tumors
    • Tapia T, Smalley SV, Kohen P, et al. Promoter hypermethylation of BRCA1 correlates with absence of expression in hereditary breast cancer tumors. Epigenetics 2008; 3(3): 157-63.
    • (2008) Epigenetics , vol.3 , Issue.3 , pp. 157-163
    • Tapia, T.1    Smalley, S.V.2    Kohen, P.3
  • 7
    • 36248970130 scopus 로고    scopus 로고
    • Immunohistochemical classification of non-BRCA1/2 tumors identifies different groups that demonstrate the heterogeneity of BRCAX families
    • Honrado E, Osorio A, Milne RL, et al. Immunohistochemical classification of non-BRCA1/2 tumors identifies different groups that demonstrate the heterogeneity of BRCAX families. Mod Pathol 2007; 20(12): 1298-306.
    • (2007) Mod Pathol , vol.20 , Issue.12 , pp. 1298-1306
    • Honrado, E.1    Osorio, A.2    Milne, R.L.3
  • 8
    • 22244449596 scopus 로고    scopus 로고
    • High-throughput protein expression analysis using tissue microarray technology of a large well-characterised series identifies biologically distinct classes of breast cancer confirming recent cDNA expression analyses
    • Abd El-Rehim DM, Ball G, Pinder SE, et al. High-throughput protein expression analysis using tissue microarray technology of a large well-characterised series identifies biologically distinct classes of breast cancer confirming recent cDNA expression analyses. Int J Cancer 2005; 116(3): 340-50.
    • (2005) Int J Cancer , vol.116 , Issue.3 , pp. 340-350
    • Abd, E.-R.D.M.1    Ball, G.2    Pinder, S.E.3
  • 9
    • 28244460828 scopus 로고    scopus 로고
    • BRCA1 promoter methylation in sporadic breast cancer is associated with reduced BRCA1 copy number and chromosome 17 aneusomy
    • Wei M, Grushko TA, Dignam J, et al. BRCA1 promoter methylation in sporadic breast cancer is associated with reduced BRCA1 copy number and chromosome 17 aneusomy. Cancer Res 2005; 65(23): 10692-9.
    • (2005) Cancer Res , vol.65 , Issue.23 , pp. 10692-10699
    • Wei, M.1    Grushko, T.A.2    Dignam, J.3
  • 10
    • 0033580432 scopus 로고    scopus 로고
    • Methylation of the BRCA1 promoter region in sporadic breast and ovarian cancer: Correlation with disease characteristics
    • Catteau A, Harris WH, Xu CF, Solomon E. Methylation of the BRCA1 promoter region in sporadic breast and ovarian cancer: correlation with disease characteristics. Oncogene 1999; 18(11): 1957-65.
    • (1999) Oncogene , vol.18 , Issue.11 , pp. 1957-1965
    • Catteau, A.1    Harris, W.H.2    Xu, C.F.3    Solomon, E.4
  • 11
    • 0033857349 scopus 로고    scopus 로고
    • Methylation of the BRCA1 promoter is associated with decreased BRCA1 mRNA levels in clinical breast cancer specimens
    • Rice JC, Ozcelik H, Maxeiner P, Andrulis I, Futscher BW. Methylation of the BRCA1 promoter is associated with decreased BRCA1 mRNA levels in clinical breast cancer specimens. Carcinogenesis 2000; 21(9): 1761-5.
    • (2000) Carcinogenesis , vol.21 , Issue.9 , pp. 1761-1765
    • Rice, J.C.1    Ozcelik, H.2    Maxeiner, P.3    Andrulis, I.4    Futscher, B.W.5
  • 12
    • 54949134514 scopus 로고    scopus 로고
    • Methylation is less abundant in BRCA1-associated compared with sporadic breast cancer
    • Suijkerbuijk KP, Fackler MJ, Sukumar S, et al. Methylation is less abundant in BRCA1-associated compared with sporadic breast cancer. Ann Oncol 2008; 19(11): 1870-4.
    • (2008) Ann Oncol , vol.19 , Issue.11 , pp. 1870-1874
    • Suijkerbuijk, K.P.1    Fackler, M.J.2    Sukumar, S.3
  • 13
    • 77649238322 scopus 로고    scopus 로고
    • DNA methylome of familial breast cancer identifies distinct profiles defined by mutation status
    • Flanagan JM, Cocciardi S, Waddell N, et al. DNA methylome of familial breast cancer identifies distinct profiles defined by mutation status. Am J Hum Genet 2010; 86(3): 420-33.
    • (2010) Am J Hum Genet , vol.86 , Issue.3 , pp. 420-433
    • Flanagan, J.M.1    Cocciardi, S.2    Waddell, N.3
  • 14
    • 84876453305 scopus 로고    scopus 로고
    • Silencing of tumor suppressor genes RASSF1A, SLIT2, and WIF1 by promoter hypermethylation in hereditary breast cancer
    • Alvarez C, Tapia T, Cornejo V, et al. Silencing of tumor suppressor genes RASSF1A, SLIT2, and WIF1 by promoter hypermethylation in hereditary breast cancer. Mol Carcinog 2013; 52(6): 475-87
    • (2013) Mol Carcinog , vol.52 , Issue.6 , pp. 475-487
    • Alvarez, C.1    Tapia, T.2    Cornejo, V.3
  • 15
    • 0037108922 scopus 로고    scopus 로고
    • SLIT2, a human homologue of the Drosophila Slit2 gene, has tumor suppressor activity and is frequently inactivated in lung and breast cancers
    • Dallol A, Da Silva NF, Viacava P, et al. SLIT2, a human homologue of the Drosophila Slit2 gene, has tumor suppressor activity and is frequently inactivated in lung and breast cancers. Cancer Res 2002; 62(20): 5874-80.
    • (2002) Cancer Res , vol.62 , Issue.20 , pp. 5874-5880
    • Dallol, A.1    da Silva, N.F.2    Viacava, P.3
  • 16
    • 34147134560 scopus 로고    scopus 로고
    • Promoter hypermethylation of p16INK4A, p14ARF, CyclinD2 and Slit2 in serum and tumor DNA from breast cancer patients
    • Sharma G, Mirza S, Prasad CP, Srivastava A, Gupta SD, Ralhan R. Promoter hypermethylation of p16INK4A, p14ARF, CyclinD2 and Slit2 in serum and tumor DNA from breast cancer patients. Life Sci 2007; 80(20): 1873-81.
    • (2007) Life Sci , vol.80 , Issue.20 , pp. 1873-1881
    • Sharma, G.1    Mirza, S.2    Prasad, C.P.3    Srivastava, A.4    Gupta, S.D.5    Ralhan, R.6
  • 17
    • 84872091298 scopus 로고    scopus 로고
    • Frequent CpG methylation of ubiquitin carboxyl-terminal hydrolase 1 (UCHL1) in sporadic and hereditary Tunisian breast cancer patients: Clinical significance
    • Trifa F, Karray-Chouayekh S, Jmaa ZB, et al. Frequent CpG methylation of ubiquitin carboxyl-terminal hydrolase 1 (UCHL1) in sporadic and hereditary Tunisian breast cancer patients: clinical significance. Med Oncol 2013; 30(1): 418.
    • (2013) Med Oncol , vol.30 , Issue.1 , pp. 418
    • Trifa, F.1    Karray-Chouayekh, S.2    Jmaa, Z.B.3
  • 18
    • 79957438722 scopus 로고    scopus 로고
    • Methylated genes in breast cancer: Associations with clinical and histopathological features in a familial breast cancer cohort
    • Swift-Scanlan T, Vang R, Blackford A, Fackler MJ, Sukumar S. Methylated genes in breast cancer: associations with clinical and histopathological features in a familial breast cancer cohort. Cancer Biol Ther 2011; 11(10): 853-65.
    • (2011) Cancer Biol Ther , vol.11 , Issue.10 , pp. 853-865
    • Swift-Scanlan, T.1    Vang, R.2    Blackford, A.3    Fackler, M.J.4    Sukumar, S.5
  • 19
    • 84860266077 scopus 로고    scopus 로고
    • Promoter methylation status and expression of estrogen receptor alpha in familial breast cancer patients
    • Wei J, Han B, Mao XY, Wei MJ, Yao F, Jin F. Promoter methylation status and expression of estrogen receptor alpha in familial breast cancer patients. Tumour Biol 2012; 33(2): 413-20.
    • (2012) Tumour Biol , vol.33 , Issue.2 , pp. 413-420
    • Wei, J.1    Han, B.2    Mao, X.Y.3    Wei, M.J.4    Yao, F.5    Jin, F.6
  • 20
    • 84870066187 scopus 로고    scopus 로고
    • RASSF1A inhibits estrogen receptor alpha expression and estrogenindependent signalling: Implications for breast cancer development
    • Thaler S, Schmidt M, Schad A, Sleeman JP. RASSF1A inhibits estrogen receptor alpha expression and estrogenindependent signalling: implications for breast cancer development. Oncogene 2012; 31(47): 4912-22
    • (2012) Oncogene , vol.31 , Issue.47 , pp. 4912-4922
    • Thaler, S.1    Schmidt, M.2    Schad, A.3    Sleeman, J.P.4
  • 21
    • 84874199614 scopus 로고    scopus 로고
    • Different methylation and MicroRNA expression pattern in male and female familial breast cancer
    • Pinto R, Pilato B, Ottini L, et al. Different methylation and MicroRNA expression pattern in male and female familial breast cancer. J Cell Physiol 2013; 228(6): 1264-9.
    • (2013) J Cell Physiol , vol.228 , Issue.6 , pp. 1264-1269
    • Pinto, R.1    Pilato, B.2    Ottini, L.3
  • 22
    • 78651242330 scopus 로고    scopus 로고
    • Global DNA methylation levels in girls with and without a family history of breast cancer
    • Wu HC, John EM, Ferris JS, et al. Global DNA methylation levels in girls with and without a family history of breast cancer. Epigenetics 2011; 6(1): 29-33.
    • (2011) Epigenetics , vol.6 , Issue.1 , pp. 29-33
    • Wu, H.C.1    John, E.M.2    Ferris, J.S.3
  • 23
    • 79551513940 scopus 로고    scopus 로고
    • Hypermethylation of tumor suppressor genes involved in critical regulatory pathways for developing a blood-based test in breast cancer
    • Radpour R, Barekati Z, Kohler C, et al. Hypermethylation of tumor suppressor genes involved in critical regulatory pathways for developing a blood-based test in breast cancer. PLoS One 2011; 6(1): e16080.
    • (2011) PLoS One , vol.6 , Issue.1
    • Radpour, R.1    Barekati, Z.2    Kohler, C.3
  • 24
    • 74549180973 scopus 로고    scopus 로고
    • Gene methylation in breast ductal fluid from BRCA1 and BRCA2 mutation carriers
    • Antill YC, Mitchell G, Johnson SA, et al. Gene methylation in breast ductal fluid from BRCA1 and BRCA2 mutation carriers. Cancer Epidemiol Biomarkers Prev 2010; 19(1): 265-74.
    • (2010) Cancer Epidemiol Biomarkers Prev , vol.19 , Issue.1 , pp. 265-274
    • Antill, Y.C.1    Mitchell, G.2    Johnson, S.A.3
  • 25
    • 33846690789 scopus 로고    scopus 로고
    • Lack of germ-line promoter methylation in BRCA1-negative families with familial breast cancer
    • Chen Y, Toland AE, McLennan J, et al. Lack of germ-line promoter methylation in BRCA1-negative families with familial breast cancer. Genet Test 2006; 10(4): 281-4.
    • (2006) Genet Test , vol.10 , Issue.4 , pp. 281-284
    • Chen, Y.1    Toland, A.E.2    McLennan, J.3
  • 26
    • 44849114690 scopus 로고    scopus 로고
    • BRCA1 promoter methylation in peripheral blood DNA of mutation negative familial breast cancer patients with a BRCA1 tumour phenotype
    • Snell C, Krypuy M, Wong EM, Loughrey MB, Dobrovic A. BRCA1 promoter methylation in peripheral blood DNA of mutation negative familial breast cancer patients with a BRCA1 tumour phenotype. Breast Cancer Res 2008; 10(1): R12.
    • (2008) Breast Cancer Res , vol.10 , Issue.1
    • Snell, C.1    Krypuy, M.2    Wong, E.M.3    Loughrey, M.B.4    Dobrovic, A.5
  • 27
    • 84872812559 scopus 로고    scopus 로고
    • Methylation profiles of the BRCA1 promoter in hereditary and sporadic breast cancer among Han Chinese
    • Pang D, Zhao Y, Xue W, et al. Methylation profiles of the BRCA1 promoter in hereditary and sporadic breast cancer among Han Chinese. Med Oncol 2012; 29(3): 1561-8.
    • (2012) Med Oncol , vol.29 , Issue.3 , pp. 1561-1568
    • Pang, D.1    Zhao, Y.2    Xue, W.3
  • 28
    • 84873045811 scopus 로고    scopus 로고
    • HOX gene methylation status analysis in patients with hereditary breast cancer
    • Pilato B, Pinto R, De Summa S, Lambo R, Paradiso A, Tommasi S. HOX gene methylation status analysis in patients with hereditary breast cancer. J Hum Genet 2013; 58(1): 51-3.
    • (2013) J Hum Genet , vol.58 , Issue.1 , pp. 51-53
    • Pilato, B.1    Pinto, R.2    de Summa, S.3    Lambo, R.4    Paradiso, A.5    Tommasi, S.6
  • 29
    • 1942469436 scopus 로고    scopus 로고
    • Quantitation of circulating DNA in the serum of breast cancer patients by real-time PCR
    • Gal S, Fidler C, Lo YM, et al. Quantitation of circulating DNA in the serum of breast cancer patients by real-time PCR. Br J Cancer 2004; 90(6): 1211-5.
    • (2004) Br J Cancer , vol.90 , Issue.6 , pp. 1211-1215
    • Gal, S.1    Fidler, C.2    Lo, Y.M.3
  • 30
    • 0034568385 scopus 로고    scopus 로고
    • Circulating DNA in plasma or serum
    • Anker P, Stroun M. Circulating DNA in plasma or serum. Medicina (B Aires) 2000; 60(5 Pt 2): 699-702.
    • (2000) Medicina (B Aires) , vol.60 , Issue.5 PART 2 , pp. 699-702
    • Anker, P.1    Stroun, M.2
  • 31
    • 77955448176 scopus 로고    scopus 로고
    • Methylated APC and GSTP1 Genes in Serum DNA Correlate with the Presence of Circulating Blood Tumor Cells and are Associated with a More Aggressive and Advanced Breast Cancer Disease
    • Matuschek C, Bolke E, Lammering G, et al. Methylated APC and GSTP1 Genes in Serum DNA Correlate with the Presence of Circulating Blood Tumor Cells and are Associated with a More Aggressive and Advanced Breast Cancer Disease. Eur J Med Res 2010; 15(7): 277-86.
    • (2010) Eur J Med Res , vol.15 , Issue.7 , pp. 277-286
    • Matuschek, C.1    Bolke, E.2    Lammering, G.3
  • 32
    • 75549091434 scopus 로고    scopus 로고
    • Circulating tumour cell detection: A direct comparison between the CellSearch System, the AdnaTest and CK-19/mammaglobin RT-PCR in patients with metastatic breast cancer
    • Van der Auwera I, Peeters D, Benoy IH, et al. Circulating tumour cell detection: a direct comparison between the CellSearch System, the AdnaTest and CK-19/mammaglobin RT-PCR in patients with metastatic breast cancer. Br J Cancer 2010; 102(2): 276-84.
    • (2010) Br J Cancer , vol.102 , Issue.2 , pp. 276-284
    • Van der Auwera, I.1    Peeters, D.2    Benoy, I.H.3
  • 33
    • 72849147946 scopus 로고    scopus 로고
    • MicroRNAs and epigenetic regulation in the mammalian inner ear: Implications for deafness
    • Friedman LM, Avraham KB. MicroRNAs and epigenetic regulation in the mammalian inner ear: implications for deafness. Mamm Genome 2009; 20(9-10): 581-603.
    • (2009) Mamm Genome , vol.20 , Issue.9-10 , pp. 581-603
    • Friedman, L.M.1    Avraham, K.B.2
  • 34
    • 11844278458 scopus 로고    scopus 로고
    • Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
    • Lewis BP, Burge CB, Bartel DP. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 2005; 120(1): 15-20.
    • (2005) Cell , vol.120 , Issue.1 , pp. 15-20
    • Lewis, B.P.1    Burge, C.B.2    Bartel, D.P.3
  • 38
    • 84861944845 scopus 로고    scopus 로고
    • BRCA1 regulates microRNA biogenesis via the DROSHA microprocessor complex
    • Kawai S, Amano A. BRCA1 regulates microRNA biogenesis via the DROSHA microprocessor complex. J Cell Biol 2012; 197(2): 201-8.
    • (2012) J Cell Biol , vol.197 , Issue.2 , pp. 201-208
    • Kawai, S.1    Amano, A.2
  • 39
    • 84867441742 scopus 로고    scopus 로고
    • Dysregulation of microRNAs in cancer
    • Chen PS, Su JL, Hung MC. Dysregulation of microRNAs in cancer. J Biomed Sci 2012; 19: 90.
    • (2012) J Biomed Sci , vol.19 , pp. 90
    • Chen, P.S.1    Su, J.L.2    Hung, M.C.3
  • 40
    • 76649105418 scopus 로고    scopus 로고
    • MicroRNA function in cancer: Oncogene or a tumor suppressor?
    • Shenouda SK, Alahari SK. MicroRNA function in cancer: oncogene or a tumor suppressor? Cancer Metastasis Rev 2009; 28(3-4): 369-78.
    • (2009) Cancer Metastasis Rev , vol.28 , Issue.3-4 , pp. 369-378
    • Shenouda, S.K.1    Alahari, S.K.2
  • 41
    • 35148886434 scopus 로고    scopus 로고
    • Tumour invasion and metastasis initiated by microRNA-10b in breast cancer
    • Ma L, Teruya-Feldstein J, Weinberg RA. Tumour invasion and metastasis initiated by microRNA-10b in breast cancer. Nature 2007; 449(7163): 682-8.
    • (2007) Nature , vol.449 , Issue.7163 , pp. 682-688
    • Ma, L.1    Teruya-Feldstein, J.2    Weinberg, R.A.3
  • 42
    • 23844555119 scopus 로고    scopus 로고
    • MicroRNA gene expression deregulation in human breast cancer
    • Iorio MV, Ferracin M, Liu CG, et al. MicroRNA gene expression deregulation in human breast cancer. Cancer Res 2005; 65(16): 7065-70.
    • (2005) Cancer Res , vol.65 , Issue.16 , pp. 7065-7070
    • Iorio, M.V.1    Ferracin, M.2    Liu, C.G.3
  • 43
    • 38049044753 scopus 로고    scopus 로고
    • Epigenetic inactivation of microRNA gene hsa-mir-9-1 in human breast cancer
    • Lehmann U, Hasemeier B, Christgen M, et al. Epigenetic inactivation of microRNA gene hsa-mir-9-1 in human breast cancer. J Pathol 2008; 214(1): 17-24.
    • (2008) J Pathol , vol.214 , Issue.1 , pp. 17-24
    • Lehmann, U.1    Hasemeier, B.2    Christgen, M.3
  • 44
    • 84862219230 scopus 로고    scopus 로고
    • Deregulated miRNAs in hereditary breast cancer revealed a role for miR-30c in regulating KRAS oncogene
    • Tanic M, Yanowsky K, Rodriguez-Antona C, et al. Deregulated miRNAs in hereditary breast cancer revealed a role for miR-30c in regulating KRAS oncogene. PLoS One 2012; 7(6): e38847.
    • (2012) PLoS One , vol.7 , Issue.6
    • Tanic, M.1    Yanowsky, K.2    Rodriguez-Antona, C.3
  • 45
    • 33144490646 scopus 로고    scopus 로고
    • A microRNA expression signature of human solid tumors defines cancer gene targets
    • Volinia S, Calin GA, Liu CG, et al. A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci U S A 2006; 103(7): 2257-61.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , Issue.7 , pp. 2257-2261
    • Volinia, S.1    Calin, G.A.2    Liu, C.G.3
  • 46
    • 53349120042 scopus 로고    scopus 로고
    • A functional polymorphism in the miR-146a gene and age of familial breast/ovarian cancer diagnosis
    • Shen J, Ambrosone CB, DiCioccio RA, Odunsi K, Lele SB, Zhao H. A functional polymorphism in the miR-146a gene and age of familial breast/ovarian cancer diagnosis. Carcinogenesis 2008; 29(10): 1963-6.
    • (2008) Carcinogenesis , vol.29 , Issue.10 , pp. 1963-1966
    • Shen, J.1    Ambrosone, C.B.2    Dicioccio, R.A.3    Odunsi, K.4    Lele, S.B.5    Zhao, H.6
  • 47
    • 78649773520 scopus 로고    scopus 로고
    • Association between hsa-mir-146a genotype and tumor age-of-onset in BRCA1/BRCA2-negative familial breast and ovarian cancer patients
    • Pastrello C, Polesel J, Della Puppa L, Viel A, Maestro R. Association between hsa-mir-146a genotype and tumor age-of-onset in BRCA1/BRCA2-negative familial breast and ovarian cancer patients. Carcinogenesis 2010; 31(12): 2124-6.
    • (2010) Carcinogenesis , vol.31 , Issue.12 , pp. 2124-2126
    • Pastrello, C.1    Polesel, J.2    della Puppa, L.3    Viel, A.4    Maestro, R.5
  • 48
    • 74049157786 scopus 로고    scopus 로고
    • Evaluation of SNPs in miR-146a, miR196a2 and miR-499 as low-penetrance alleles in German and Italian familial breast cancer cases
    • Catucci I, Yang R, Verderio P, et al. Evaluation of SNPs in miR-146a, miR196a2 and miR-499 as low-penetrance alleles in German and Italian familial breast cancer cases. Hum Mutat 2010; 31(1): E1052-7.
    • (2010) Hum Mutat , vol.31 , Issue.1
    • Catucci, I.1    Yang, R.2    Verderio, P.3
  • 49
    • 58749083044 scopus 로고    scopus 로고
    • Novel genetic variants in microRNA genes and familial breast cancer
    • Shen J, Ambrosone CB, Zhao H. Novel genetic variants in microRNA genes and familial breast cancer. Int J Cancer 2009; 124(5): 1178-82.
    • (2009) Int J Cancer , vol.124 , Issue.5 , pp. 1178-1182
    • Shen, J.1    Ambrosone, C.B.2    Zhao, H.3
  • 50
    • 77953122376 scopus 로고    scopus 로고
    • A genetic variant in the pre-miR-27a oncogene is associated with a reduced familial breast cancer risk
    • Yang R, Schlehe B, Hemminki K, et al. A genetic variant in the pre-miR-27a oncogene is associated with a reduced familial breast cancer risk. Breast Cancer Res Treat 2010; 121(3): 693-702.
    • (2010) Breast Cancer Res Treat , vol.121 , Issue.3 , pp. 693-702
    • Yang, R.1    Schlehe, B.2    Hemminki, K.3
  • 51
    • 84863720843 scopus 로고    scopus 로고
    • The SNP rs895819 in miR-27a is not associated with familial breast cancer risk in Italians
    • Catucci I, Verderio P, Pizzamiglio S, et al. The SNP rs895819 in miR-27a is not associated with familial breast cancer risk in Italians. Breast Cancer Res Treat 2012; 133(2): 805-7.
    • (2012) Breast Cancer Res Treat , vol.133 , Issue.2 , pp. 805-807
    • Catucci, I.1    Verderio, P.2    Pizzamiglio, S.3
  • 52
    • 48749122914 scopus 로고    scopus 로고
    • Circulating microRNAs as stable blood-based markers for cancer detection
    • Mitchell PS, Parkin RK, Kroh EM, et al. Circulating microRNAs as stable blood-based markers for cancer detection. Proc Natl Acad Sci U S A 2008; 105(30): 10513-8.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , Issue.30 , pp. 10513-10518
    • Mitchell, P.S.1    Parkin, R.K.2    Kroh, E.M.3
  • 54
    • 78049339462 scopus 로고    scopus 로고
    • Circulating microRNAs as blood-based markers for patients with primary and metastatic breast cancer
    • Roth C, Rack B, Muller V, Janni W, Pantel K, Schwarzenbach H. Circulating microRNAs as blood-based markers for patients with primary and metastatic breast cancer. Breast Cancer Res 2010; 12(6): R90.
    • (2010) Breast Cancer Res , vol.12 , Issue.6
    • Roth, C.1    Rack, B.2    Muller, V.3    Janni, W.4    Pantel, K.5    Schwarzenbach, H.6
  • 55
    • 84859810024 scopus 로고    scopus 로고
    • Circulating MiR-125b as a marker predicting chemoresistance in breast cancer
    • Wang H, Tan G, Dong L, et al. Circulating MiR-125b as a marker predicting chemoresistance in breast cancer. PLoS One 2012; 7(4): e34210.
    • (2012) PLoS One , vol.7 , Issue.4
    • Wang, H.1    Tan, G.2    Dong, L.3
  • 56
    • 84860383096 scopus 로고    scopus 로고
    • Analysis of serum genome-wide microRNAs for breast cancer detection
    • Wu Q, Wang C, Lu Z, Guo L, Ge Q. Analysis of serum genome-wide microRNAs for breast cancer detection. Clin Chim Acta 2012; 413(13-14): 1058-65.
    • (2012) Clin Chim Acta , vol.413 , Issue.13-14 , pp. 1058-1065
    • Wu, Q.1    Wang, C.2    Lu, Z.3    Guo, L.4    Ge, Q.5
  • 57
    • 77649138141 scopus 로고    scopus 로고
    • Circulating microRNAs as novel minimally invasive biomarkers for breast cancer
    • Heneghan HM, Miller N, Lowery AJ, Sweeney KJ, Newell J, Kerin MJ. Circulating microRNAs as novel minimally invasive biomarkers for breast cancer. Ann Surg 2010; 251(3): 499-505.
    • (2010) Ann Surg , vol.251 , Issue.3 , pp. 499-505
    • Heneghan, H.M.1    Miller, N.2    Lowery, A.J.3    Sweeney, K.J.4    Newell, J.5    Kerin, M.J.6
  • 58
    • 84864615523 scopus 로고    scopus 로고
    • miRNA expression profiling for identification of potential breast cancer biomarkers
    • Tjensvoll K, Svendsen KN, Reuben JM, et al. miRNA expression profiling for identification of potential breast cancer biomarkers. Biomarkers 2012; 17(5): 463-70.
    • (2012) Biomarkers , vol.17 , Issue.5 , pp. 463-470
    • Tjensvoll, K.1    Svendsen, K.N.2    Reuben, J.M.3
  • 59
    • 4143150688 scopus 로고    scopus 로고
    • Immunohistochemical and clinical characterization of the basal-like subtype of invasive breast carcinoma
    • Nielsen TO, Hsu FD, Jensen K, et al. Immunohistochemical and clinical characterization of the basal-like subtype of invasive breast carcinoma. Clin Cancer Res 2004; 10(16): 5367-74
    • (2004) Clin Cancer Res , vol.10 , Issue.16 , pp. 5367-5374
    • Nielsen, T.O.1    Hsu, F.D.2    Jensen, K.3
  • 60
    • 37248999372 scopus 로고    scopus 로고
    • Triple negative tumours: A critical review
    • Reis-Filho JS, Tutt AN. Triple negative tumours: a critical review. Histopathology 2008; 52(1): 108-18.
    • (2008) Histopathology , vol.52 , Issue.1 , pp. 108-118
    • Reis-Filho, J.S.1    Tutt, A.N.2
  • 61
    • 4944229642 scopus 로고    scopus 로고
    • Hallmarks of 'BRCAness' in sporadic cancers
    • Turner N, Tutt A, Ashworth A. Hallmarks of 'BRCAness' in sporadic cancers. Nat Rev Cancer 2004; 4(10): 814-9.
    • (2004) Nat Rev Cancer , vol.4 , Issue.10 , pp. 814-819
    • Turner, N.1    Tutt, A.2    Ashworth, A.3
  • 62
    • 33749022506 scopus 로고    scopus 로고
    • Basal-like breast cancer and the BRCA1 phenotype
    • Turner NC, Reis-Filho JS. Basal-like breast cancer and the BRCA1 phenotype. Oncogene 2006; 25(43): 5846-53.
    • (2006) Oncogene , vol.25 , Issue.43 , pp. 5846-5853
    • Turner, N.C.1    Reis-Filho, J.S.2
  • 63
    • 0141429017 scopus 로고    scopus 로고
    • Germline BRCA1 mutations and a basal epithelial phenotype in breast cancer
    • Foulkes WD, Stefansson IM, Chappuis PO, et al. Germline BRCA1 mutations and a basal epithelial phenotype in breast cancer. J Natl Cancer Inst 2003; 95(19): 1482-5.
    • (2003) J Natl Cancer Inst , vol.95 , Issue.19 , pp. 1482-1485
    • Foulkes, W.D.1    Stefansson, I.M.2    Chappuis, P.O.3
  • 64
    • 22344443194 scopus 로고    scopus 로고
    • Prediction of BRCA1 status in patients with breast cancer using estrogen receptor and basal phenotype
    • Lakhani SR, Reis-Filho JS, Fulford L, et al. Prediction of BRCA1 status in patients with breast cancer using estrogen receptor and basal phenotype. Clin Cancer Res 2005; 11(14): 5175-80.
    • (2005) Clin Cancer Res , vol.11 , Issue.14 , pp. 5175-5180
    • Lakhani, S.R.1    Reis-Filho, J.S.2    Fulford, L.3
  • 65
    • 64749086562 scopus 로고    scopus 로고
    • The prevalence of BRCA1 mutations among young women with triplenegative breast cancer
    • Young SR, Pilarski RT, Donenberg T, et al. The prevalence of BRCA1 mutations among young women with triplenegative breast cancer. BMC Cancer 2009; 9: 86.
    • (2009) BMC Cancer , vol.9 , pp. 86
    • Young, S.R.1    Pilarski, R.T.2    Donenberg, T.3
  • 66
    • 33847022042 scopus 로고    scopus 로고
    • BRCA1 dysfunction in sporadic basal-like breast cancer
    • Turner NC, Reis-Filho JS, Russell AM, et al. BRCA1 dysfunction in sporadic basal-like breast cancer. Oncogene 2007; 26(14): 2126-32.
    • (2007) Oncogene , vol.26 , Issue.14 , pp. 2126-2132
    • Turner, N.C.1    Reis-Filho, J.S.2    Russell, A.M.3
  • 67
    • 22244449596 scopus 로고    scopus 로고
    • High-throughput protein expression analysis using tissue microarray technology of a large well-characterised series identifies biologically distinct classes of breast cancer confirming recent cDNA expression analyses
    • Abd El-Rehim DM, Ball G, Pinder SE, et al. High-throughput protein expression analysis using tissue microarray technology of a large well-characterised series identifies biologically distinct classes of breast cancer confirming recent cDNA expression analyses. Int J Cancer 2005; 116(3): 340-50.
    • (2005) Int J Cancer , vol.116 , Issue.3 , pp. 340-350
    • Abd, E.-R.D.M.1    Ball, G.2    Pinder, S.E.3
  • 68
    • 0034607234 scopus 로고    scopus 로고
    • Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors
    • Esteller M, Silva JM, Dominguez G, et al. Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors. J Natl Cancer Inst 2000; 92(7): 564-9.
    • (2000) J Natl Cancer Inst , vol.92 , Issue.7 , pp. 564-569
    • Esteller, M.1    Silva, J.M.2    Dominguez, G.3
  • 69
    • 0043246688 scopus 로고    scopus 로고
    • Distinct genetic and epigenetic changes in medullary breast cancer
    • Osin P, Lu YJ, Stone J, et al. Distinct genetic and epigenetic changes in medullary breast cancer. Int J Surg Pathol 2003; 11(3): 153-8.
    • (2003) Int J Surg Pathol , vol.11 , Issue.3 , pp. 153-158
    • Osin, P.1    Lu, Y.J.2    Stone, J.3
  • 71
    • 77149179427 scopus 로고    scopus 로고
    • Genomic profiling of breast tumours in relation to BRCA abnormalities and phenotypes
    • Stefansson OA, Jonasson JG, Johannsson OT, et al. Genomic profiling of breast tumours in relation to BRCA abnormalities and phenotypes. Breast Cancer Res 2009; 11(4): R47.
    • (2009) Breast Cancer Res , vol.11 , Issue.4
    • Stefansson, O.A.1    Jonasson, J.G.2    Johannsson, O.T.3
  • 73
    • 79957562586 scopus 로고    scopus 로고
    • CpG island hypermethylation of BRCA1 and loss of pRb as co-occurring events in basal/triple-negative breast cancer
    • Stefansson OA, Jonasson JG, Olafsdottir K, et al. CpG island hypermethylation of BRCA1 and loss of pRb as co-occurring events in basal/triple-negative breast cancer. Epigenetics 2011; 6(5): 638-49.
    • (2011) Epigenetics , vol.6 , Issue.5 , pp. 638-649
    • Stefansson, O.A.1    Jonasson, J.G.2    Olafsdottir, K.3
  • 74
    • 77954406621 scopus 로고    scopus 로고
    • Basal-like breast cancer displays distinct patterns of promoter methylation
    • Lee JS, Fackler MJ, Lee JH, et al. Basal-like breast cancer displays distinct patterns of promoter methylation. Cancer Biol Ther 2010; 9(12): 1017-24.
    • (2010) Cancer Biol Ther , vol.9 , Issue.12 , pp. 1017-1024
    • Lee, J.S.1    Fackler, M.J.2    Lee, J.H.3
  • 75
    • 84863988129 scopus 로고    scopus 로고
    • Methylation of O6-methylguanine-DNA methyltransferase (MGMT) promoter gene in triple-negative breast cancer patients
    • Fumagalli C, Pruneri G, Possanzini P, et al. Methylation of O6-methylguanine-DNA methyltransferase (MGMT) promoter gene in triple-negative breast cancer patients. Breast Cancer Res Treat 2012; 134(1): 131-7.
    • (2012) Breast Cancer Res Treat , vol.134 , Issue.1 , pp. 131-137
    • Fumagalli, C.1    Pruneri, G.2    Possanzini, P.3
  • 76
    • 80051832078 scopus 로고    scopus 로고
    • miR-221/222 targeting of trichorhinophalangeal 1 (TRPS1) promotes epithelial-to-mesenchymal transition in breast cancer
    • Stinson S, Lackner MR, Adai AT, et al. miR-221/222 targeting of trichorhinophalangeal 1 (TRPS1) promotes epithelial-to-mesenchymal transition in breast cancer. Sci Signal 2011; 4(186): pt5.
    • (2011) Sci Signal , vol.4 , Issue.186 , pp. 5
    • Stinson, S.1    Lackner, M.R.2    Adai, A.T.3
  • 77
    • 57649174634 scopus 로고    scopus 로고
    • MicroRNA-221/222 negatively regulates estrogen receptor alpha and is associated with tamoxifen resistance in breast cancer
    • Zhao JJ, Lin J, Yang H, et al. MicroRNA-221/222 negatively regulates estrogen receptor alpha and is associated with tamoxifen resistance in breast cancer. J Biol Chem 2008; 283(45): 31079-86.
    • (2008) J Biol Chem , vol.283 , Issue.45 , pp. 31079-31086
    • Zhao, J.J.1    Lin, J.2    Yang, H.3
  • 78
    • 84868100929 scopus 로고    scopus 로고
    • MicroRNA-200 family modulation in distinct breast cancer phenotypes
    • Castilla MA, Diaz-Martin J, Sarrio D, et al. MicroRNA-200 family modulation in distinct breast cancer phenotypes. PLoS One 2012; 7(10): e47709.
    • (2012) PLoS One , vol.7 , Issue.10
    • Castilla, M.A.1    Diaz-Martin, J.2    Sarrio, D.3
  • 79
    • 79955575393 scopus 로고    scopus 로고
    • Down-regulation of BRCA1 expression by miR-146a and miR-146b-5p in triple negative sporadic breast cancers
    • Garcia AI, Buisson M, Bertrand P, et al. Down-regulation of BRCA1 expression by miR-146a and miR-146b-5p in triple negative sporadic breast cancers. EMBO Mol Med 2011; 3(5): 279-90.
    • (2011) EMBO Mol Med , vol.3 , Issue.5 , pp. 279-290
    • Garcia, A.I.1    Buisson, M.2    Bertrand, P.3
  • 80
    • 84859219889 scopus 로고    scopus 로고
    • High expression of microRNA-210 is an independent factor indicating a poor prognosis in Japanese triple-negative breast cancer patients
    • Toyama T, Kondo N, Endo Y, et al. High expression of microRNA-210 is an independent factor indicating a poor prognosis in Japanese triple-negative breast cancer patients. Jpn J Clin Oncol 2012; 42(4): 256-63.
    • (2012) Jpn J Clin Oncol , vol.42 , Issue.4 , pp. 256-263
    • Toyama, T.1    Kondo, N.2    Endo, Y.3
  • 81
    • 84858725701 scopus 로고    scopus 로고
    • MiR-34b is associated with clinical outcome in triple-negative breast cancer patients
    • Svoboda M, Sana J, Redova M, et al. MiR-34b is associated with clinical outcome in triple-negative breast cancer patients. Diagn Pathol 2012; 7: 31.
    • (2012) Diagn Pathol , vol.7 , pp. 31
    • Svoboda, M.1    Sana, J.2    Redova, M.3
  • 83
    • 77956402239 scopus 로고    scopus 로고
    • MicroRNA-210 regulates mitochondrial free radical response to hypoxia and krebs cycle in cancer cells by targeting iron sulfur cluster protein ISCU
    • Favaro E, Ramachandran A, McCormick R, et al. MicroRNA-210 regulates mitochondrial free radical response to hypoxia and krebs cycle in cancer cells by targeting iron sulfur cluster protein ISCU. PLoS One 2010; 5(4): e10345.
    • (2010) PLoS One , vol.5 , Issue.4
    • Favaro, E.1    Ramachandran, A.2    McCormick, R.3
  • 84
    • 62449117918 scopus 로고    scopus 로고
    • MiR-34, SIRT1 and p53: The feedback loop
    • Yamakuchi M, Lowenstein CJ. MiR-34, SIRT1 and p53: the feedback loop. Cell Cycle 2009; 8(5): 712-5.
    • (2009) Cell Cycle , vol.8 , Issue.5 , pp. 712-715
    • Yamakuchi, M.1    Lowenstein, C.J.2
  • 85
    • 84861845402 scopus 로고    scopus 로고
    • The updated biology of hypoxia-inducible factor
    • Greer SN, Metcalf JL, Wang Y, Ohh M. The updated biology of hypoxia-inducible factor. EMBO J 2012; 31(11): 2448-60.
    • (2012) EMBO J , vol.31 , Issue.11 , pp. 2448-2460
    • Greer, S.N.1    Metcalf, J.L.2    Wang, Y.3    Ohh, M.4
  • 86
    • 84865507272 scopus 로고    scopus 로고
    • Hypoxia regulates CD44 and its variant isoforms through HIF-1alpha in triple negative breast cancer
    • Krishnamachary B, Penet MF, Nimmagadda S, et al. Hypoxia regulates CD44 and its variant isoforms through HIF-1alpha in triple negative breast cancer. PLoS One 2012; 7(8): e44078.
    • (2012) PLoS One , vol.7 , Issue.8
    • Krishnamachary, B.1    Penet, M.F.2    Nimmagadda, S.3
  • 87
    • 84862276687 scopus 로고    scopus 로고
    • MicroRNA-203 suppresses cell proliferation and migration by targeting BIRC5 and LASP1 in human triple-negative breast cancer cells
    • Wang C, Zheng X, Shen C, Shi Y. MicroRNA-203 suppresses cell proliferation and migration by targeting BIRC5 and LASP1 in human triple-negative breast cancer cells. J Exp Clin Cancer Res 2012; 31: 58.
    • (2012) J Exp Clin Cancer Res , vol.31 , pp. 58
    • Wang, C.1    Zheng, X.2    Shen, C.3    Shi, Y.4
  • 88
    • 84864296533 scopus 로고    scopus 로고
    • Oncosuppressive role of p53-induced miR-205 in triple negative breast cancer
    • Piovan C, Palmieri D, Di Leva G, et al. Oncosuppressive role of p53-induced miR-205 in triple negative breast cancer. Mol Oncol 2012; 6(4): 458-72.
    • (2012) Mol Oncol , vol.6 , Issue.4 , pp. 458-472
    • Piovan, C.1    Palmieri, D.2    Di Leva, G.3
  • 89
    • 65549110881 scopus 로고    scopus 로고
    • microRNA-205 regulates HER3 in human breast cancer
    • Iorio MV, Casalini P, Piovan C, et al. microRNA-205 regulates HER3 in human breast cancer. Cancer Res 2009; 69(6): 2195-200.
    • (2009) Cancer Res , vol.69 , Issue.6 , pp. 2195-2200
    • Iorio, M.V.1    Casalini, P.2    Piovan, C.3
  • 90
    • 84873551499 scopus 로고    scopus 로고
    • Integrated MicroRNA and mRNA Signatures Associated with Survival in Triple Negative Breast Cancer
    • Cascione L, Gasparini P, Lovat F, et al. Integrated MicroRNA and mRNA Signatures Associated with Survival in Triple Negative Breast Cancer. PLoS One 2013; 8(2): e55910.
    • (2013) PLoS One , vol.8 , Issue.2
    • Cascione, L.1    Gasparini, P.2    Lovat, F.3
  • 91
    • 33846207899 scopus 로고    scopus 로고
    • Diverse gene expression and DNA methylation profiles correlate with differential adaptation of breast cancer cells to the antiestrogens tamoxifen and fulvestrant
    • Fan M, Yan PS, Hartman-Frey C, et al. Diverse gene expression and DNA methylation profiles correlate with differential adaptation of breast cancer cells to the antiestrogens tamoxifen and fulvestrant. Cancer Res 2006; 66(24): 11954-66.
    • (2006) Cancer Res , vol.66 , Issue.24 , pp. 11954-11966
    • Fan, M.1    Yan, P.S.2    Hartman-Frey, C.3
  • 92
    • 0035861037 scopus 로고    scopus 로고
    • Tamoxifen and breast cancer incidence among women with inherited mutations in BRCA1 and BRCA2: National Surgical Adjuvant Breast and Bowel Project (NSABP-P1) Breast Cancer Prevention Trial
    • King MC, Wieand S, Hale K, et al. Tamoxifen and breast cancer incidence among women with inherited mutations in BRCA1 and BRCA2: National Surgical Adjuvant Breast and Bowel Project (NSABP-P1) Breast Cancer Prevention Trial. JAMA 2001; 286(18): 2251-6.
    • (2001) JAMA , vol.286 , Issue.18 , pp. 2251-2256
    • King, M.C.1    Wieand, S.2    Hale, K.3
  • 93
    • 13944250245 scopus 로고    scopus 로고
    • Circulating tumor-specific DNA: A marker for monitoring efficacy of adjuvant therapy in cancer patients
    • Fiegl H, Millinger S, Mueller-Holzner E, et al. Circulating tumor-specific DNA: a marker for monitoring efficacy of adjuvant therapy in cancer patients. Cancer Res 2005; 65(4): 1141-5.
    • (2005) Cancer Res , vol.65 , Issue.4 , pp. 1141-1145
    • Fiegl, H.1    Millinger, S.2    Mueller-Holzner, E.3
  • 94
    • 15044363940 scopus 로고    scopus 로고
    • Tamoxifen-resistant breast cancers show less frequent methylation of the estrogen receptor beta but not the estrogen receptor alpha gene
    • Chang HG, Kim SJ, Chung KW, et al. Tamoxifen-resistant breast cancers show less frequent methylation of the estrogen receptor beta but not the estrogen receptor alpha gene. J Mol Med (Berl) 2005; 83(2): 132-9.
    • (2005) J Mol Med (Berl) , vol.83 , Issue.2 , pp. 132-139
    • Chang, H.G.1    Kim, S.J.2    Chung, K.W.3
  • 96
    • 82455192395 scopus 로고    scopus 로고
    • Role of PTEN promoter methylation in tamoxifen-resistant breast cancer cells
    • Phuong NT, Kim SK, Lim SC, et al. Role of PTEN promoter methylation in tamoxifen-resistant breast cancer cells. Breast Cancer Res Treat 2011; 130(1): 73-83.
    • (2011) Breast Cancer Res Treat , vol.130 , Issue.1 , pp. 73-83
    • Phuong, N.T.1    Kim, S.K.2    Lim, S.C.3
  • 97
    • 78650264443 scopus 로고    scopus 로고
    • Downregulation of miR-342 is associated with tamoxifen resistant breast tumors
    • Cittelly DM, Das PM, Spoelstra NS, et al. Downregulation of miR-342 is associated with tamoxifen resistant breast tumors. Mol Cancer 2010; 9: 317.
    • (2010) Mol Cancer , vol.9 , pp. 317
    • Cittelly, D.M.1    Das, P.M.2    Spoelstra, N.S.3
  • 98
    • 84874735111 scopus 로고    scopus 로고
    • Re-expression of microRNA-375 reverses both tamoxifen resistance and accompanying EMT-like properties in breast cancer
    • Ward A, Balwierz A, Zhang JD, et al. Re-expression of microRNA-375 reverses both tamoxifen resistance and accompanying EMT-like properties in breast cancer. Oncogene 2013; 32(9): 1173-82
    • (2013) Oncogene , vol.32 , Issue.9 , pp. 1173-1182
    • Ward, A.1    Balwierz, A.2    Zhang, J.D.3
  • 99
    • 56449092072 scopus 로고    scopus 로고
    • MicroRNA-221/222 confers tamoxifen resistance in breast cancer by targeting p27Kip1
    • Miller TE, Ghoshal K, Ramaswamy B, et al. MicroRNA-221/222 confers tamoxifen resistance in breast cancer by targeting p27Kip1. J Biol Chem 2008; 283(44): 29897-903.
    • (2008) J Biol Chem , vol.283 , Issue.44 , pp. 29897-29903
    • Miller, T.E.1    Ghoshal, K.2    Ramaswamy, B.3
  • 100
    • 48549099077 scopus 로고    scopus 로고
    • miR-206 Expression is down-regulated in estrogen receptor alpha-positive human breast cancer
    • Kondo N, Toyama T, Sugiura H, Fujii Y, Yamashita H. miR-206 Expression is down-regulated in estrogen receptor alpha-positive human breast cancer. Cancer Res 2008; 68(13): 5004-8.
    • (2008) Cancer Res , vol.68 , Issue.13 , pp. 5004-5008
    • Kondo, N.1    Toyama, T.2    Sugiura, H.3    Fujii, Y.4    Yamashita, H.5
  • 101
    • 79952281614 scopus 로고    scopus 로고
    • MicroRNA-221/222 confers breast cancer fulvestrant resistance by regulating multiple signaling pathways
    • Rao X, Di Leva G, Li M, et al. MicroRNA-221/222 confers breast cancer fulvestrant resistance by regulating multiple signaling pathways. Oncogene 2011; 30(9): 1082-97.
    • (2011) Oncogene , vol.30 , Issue.9 , pp. 1082-1097
    • Rao, X.1    Di Leva, G.2    Li, M.3
  • 102
    • 79951810419 scopus 로고    scopus 로고
    • MicroRNA-101-mediated Akt activation and estrogenindependent growth
    • Sachdeva M, Wu H, Ru P, Hwang L, Trieu V, Mo YY. MicroRNA-101-mediated Akt activation and estrogenindependent growth. Oncogene 2011; 30(7): 822-31.
    • (2011) Oncogene , vol.30 , Issue.7 , pp. 822-831
    • Sachdeva, M.1    Wu, H.2    Ru, P.3    Hwang, L.4    Trieu, V.5    Mo, Y.Y.6
  • 103
    • 84873120034 scopus 로고    scopus 로고
    • miR-342 is associated with estrogen receptor-alpha expression and response to tamoxifen in breast cancer
    • He YJ, Wu JZ, Ji MH, et al. miR-342 is associated with estrogen receptor-alpha expression and response to tamoxifen in breast cancer. Exp Ther Med 2013; 5(3): 813-8.
    • (2013) Exp Ther Med , vol.5 , Issue.3 , pp. 813-818
    • He, Y.J.1    Wu, J.Z.2    Ji, M.H.3
  • 104
    • 79954748720 scopus 로고    scopus 로고
    • MicroRNA-30c expression level is an independent predictor of clinical benefit of endocrine therapy in advanced estrogen receptor positive breast cancer
    • Rodriguez-Gonzalez FG, Sieuwerts AM, Smid M, et al. MicroRNA-30c expression level is an independent predictor of clinical benefit of endocrine therapy in advanced estrogen receptor positive breast cancer. Breast Cancer Res Treat 2011; 127(1): 43-51.
    • (2011) Breast Cancer Res Treat , vol.127 , Issue.1 , pp. 43-51
    • Rodriguez-Gonzalez, F.G.1    Sieuwerts, A.M.2    Smid, M.3
  • 105
    • 77956995581 scopus 로고    scopus 로고
    • Alterations of microRNAs and their targets are associated with acquired resistance of MCF-7 breast cancer cells to cisplatin
    • Pogribny IP, Filkowski JN, Tryndyak VP, Golubov A, Shpyleva SI, Kovalchuk O. Alterations of microRNAs and their targets are associated with acquired resistance of MCF-7 breast cancer cells to cisplatin. Int J Cancer 2010; 127(8): 1785-94.
    • (2010) Int J Cancer , vol.127 , Issue.8 , pp. 1785-1794
    • Pogribny, I.P.1    Filkowski, J.N.2    Tryndyak, V.P.3    Golubov, A.4    Shpyleva, S.I.5    Kovalchuk, O.6
  • 106
    • 84857411956 scopus 로고    scopus 로고
    • Anti-miR-203 Upregulates SOCS3 Expression in Breast Cancer Cells and Enhances Cisplatin Chemosensitivity
    • Ru P, Steele R, Hsueh EC, Ray RB. Anti-miR-203 Upregulates SOCS3 Expression in Breast Cancer Cells and Enhances Cisplatin Chemosensitivity. Genes Cancer 2011; 2(7): 720-7.
    • (2011) Genes Cancer , vol.2 , Issue.7 , pp. 720-727
    • Ru, P.1    Steele, R.2    Hsueh, E.C.3    Ray, R.B.4
  • 107
    • 77949908546 scopus 로고    scopus 로고
    • Efficacy of neoadjuvant Cisplatin in triple-negative breast cancer
    • Silver DP, Richardson AL, Eklund AC, et al. Efficacy of neoadjuvant Cisplatin in triple-negative breast cancer. J Clin Oncol 2010; 28(7): 1145-53.
    • (2010) J Clin Oncol , vol.28 , Issue.7 , pp. 1145-1153
    • Silver, D.P.1    Richardson, A.L.2    Eklund, A.C.3
  • 108
    • 80054765897 scopus 로고    scopus 로고
    • Assays for hypermethylation of the BRCA1 gene promoter in tumor cells to predict sensitivity to PARP-inhibitor therapy
    • Ibragimova I, Cairns P. Assays for hypermethylation of the BRCA1 gene promoter in tumor cells to predict sensitivity to PARP-inhibitor therapy. Methods Mol Biol 2011; 780: 277-91.
    • (2011) Methods Mol Biol , vol.780 , pp. 277-291
    • Ibragimova, I.1    Cairns, P.2
  • 109
    • 78651468714 scopus 로고    scopus 로고
    • miR-182-mediated downregulation of BRCA1 impacts DNA repair and sensitivity to PARP inhibitors
    • Moskwa P, Buffa FM, Pan Y, et al. miR-182-mediated downregulation of BRCA1 impacts DNA repair and sensitivity to PARP inhibitors. Mol Cell 2011; 41(2): 210-20.
    • (2011) Mol Cell , vol.41 , Issue.2 , pp. 210-220
    • Moskwa, P.1    Buffa, F.M.2    Pan, Y.3
  • 110
    • 78651468730 scopus 로고    scopus 로고
    • A new role for miR-182 in DNA repair
    • Yao E, Ventura A. A new role for miR-182 in DNA repair. Mol Cell 2011; 41(2): 135-7.
    • (2011) Mol Cell , vol.41 , Issue.2 , pp. 135-137
    • Yao, E.1    Ventura, A.2
  • 111
    • 84855180543 scopus 로고    scopus 로고
    • MicroRNA miR-335 is crucial for the BRCA1 regulatory cascade in breast cancer development
    • Heyn H, Engelmann M, Schreek S, et al. MicroRNA miR-335 is crucial for the BRCA1 regulatory cascade in breast cancer development. Int J Cancer 2011; 129(12): 2797-806.
    • (2011) Int J Cancer , vol.129 , Issue.12 , pp. 2797-2806
    • Heyn, H.1    Engelmann, M.2    Schreek, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.