miR-221/222 targeting of trichorh inophalangeal 1 (TRPS1) promotes epithelial-to-mesenchymal transition in breast cancer

Science Signaling

Volumn 4, Issue 186, 2011, Pages

  Stinson, Susanna ^a   Lackner, Mark R ^a   Adai, Alex T ^b   Yu, Nancy ^a   Kim, Hyo Jin ^a   O'Brien, Carol ^a   Spoerke, Jill ^a   Jhunjhunwala, Suchit ^a   Boyd, Zachary ^a   Januario, Thomas ^a   Newman, Robert J ^a   Yue, Peng ^a   Bourgon, Richard ^a   Modrusan, Zora ^a   Stern, Howard M ^a   Warming, Søren ^a   De Sauvage, Frederic J ^a   Amler, Lukas ^a   Yeh, Ru Fang ^a   Dornan, David ^a  

^a GENENTECH INC   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; HOMEODOMAIN PROTEIN; MESSENGER RNA; MICRORNA; MICRORNA 221; MICRORNA 222; MITOGEN ACTIVATED PROTEIN KINASE KINASE; PROGESTERONE RECEPTOR; RAS PROTEIN; TRANSCRIPTION FACTOR FRA 1; TRICHORHINOPHALANGEAL SYNDROME TYPE 1 PROTEIN; TUMOR MARKER; UNCLASSIFIED DRUG; UVOMORULIN; VIMENTIN; ZINC FINGER E BOX BINDING HOMEOBOX 2; DNA BINDING PROTEIN; MIRN221 MICRORNA, HUMAN; MIRN222 MICRORNA, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; PROTEIN C FOS; REPRESSOR PROTEIN; RNA; TRANSCRIPTION FACTOR; TRPS1 PROTEIN, HUMAN; TUMOR PROTEIN; ZEB2 PROTEIN, HUMAN;

3' UNTRANSLATED REGION; BASAL LIKE BREAST CANCER; BINDING SITE; BREAST CANCER; BREAST CARCINOGENESIS; CANCER CLASSIFICATION; CANCER INVASION; CELL MIGRATION; CELL STRUCTURE; CONFERENCE PAPER; CONTROLLED STUDY; DOWN REGULATION; EPITHELIAL MESENCHYMAL TRANSITION; GENE EXPRESSION REGULATION; GENETIC ANALYSIS; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LUMINAL BREAST CANCER; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN LOCALIZATION; RNA SEQUENCE; SIGNAL TRANSDUCTION; UPREGULATION; WILD TYPE; ARTICLE; BIOSYNTHESIS; BREAST TUMOR; CELL MOTION; FEMALE; GENETICS; METABOLISM; PATHOLOGY;

3' UNTRANSLATED REGIONS; BREAST NEOPLASMS; CELL MOVEMENT; DNA-BINDING PROTEINS; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HOMEODOMAIN PROTEINS; HUMANS; MAP KINASE KINASE KINASES; MICRORNAS; NEOPLASM INVASIVENESS; NEOPLASM PROTEINS; PROTO-ONCOGENE PROTEINS C-FOS; REPRESSOR PROTEINS; RNA, NEOPLASM; TRANSCRIPTION FACTORS;

EID: 80051832078     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.2002258     Document Type: Conference Paper

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20. Competing interests: All authors are employees of Genentech Inc., except A.T.A.