Impaired endocannabinoid signalling in the rostral ventromedial medulla underpins genotype-dependent hyper-responsivity to noxious stimuli

Pain

Volumn 155, Issue 1, 2014, Pages 69-79

  Rea, Kieran ^a   Olango, Weredeselam M ^a   Okine, Bright N ^a   Madasu, Manish K ^a   McGuire, Iseult C ^a   Coyle, Kathleen ^a   Harhen, Brendan ^a   Roche, Michelle ^a   Finn, David P ^a  

^a NATIONAL UNIVERSITY OF IRELAND   (Ireland)

Author keywords

Affect; Anandamide; Cannabinoid1 (CB1) receptor; Fatty acid amide hydrolase (FAAH); Formalin; Pain; Rostroventromedial medulla (RVM); Wistar Kyoto rat

Indexed keywords

CANNABINOID 1 RECEPTOR; ENDOCANNABINOID; FATTY ACID AMIDASE; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENOTYPE; HYPERALGESIA; MALE; MEDULLA OBLONGATA; NEUROMODULATION; NOCICEPTIVE STIMULATION; NONHUMAN; PRIORITY JOURNAL; RAT; ROSTRAL VENTROMEDIAL MEDULLA; SIGNAL TRANSDUCTION;

AFFECT; ANANDAMIDE; CANNABINOID(1) (CB(1)) RECEPTOR; FATTY ACID AMIDE HYDROLASE (FAAH); FORMALIN; PAIN; ROSTROVENTROMEDIAL MEDULLA (RVM); WISTAR-KYOTO RAT;

ANIMALS; CANNABINOID RECEPTOR MODULATORS; DEPRESSION; DISEASE MODELS, ANIMAL; ENDOCANNABINOIDS; FORMALDEHYDE; GENE EXPRESSION REGULATION; HYPERKINESIS; MALE; MEDULLA OBLONGATA; MICRODISSECTION; NOCICEPTION; PAIN MEASUREMENT; RANDOM ALLOCATION; RATS; RATS, INBRED WKY; RATS, SPRAGUE-DAWLEY; RECEPTOR, CANNABINOID, CB1; SIGNAL TRANSDUCTION;

EID: 84891835445     PISSN: 03043959     EISSN: 18726623     Source Type: Journal    
DOI: 10.1016/j.pain.2013.09.012     Document Type: Article

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