Evidence for visceral hypersensitivity in high-anxiety rats

Physiology and Behavior

Volumn 69, Issue 3, 2000, Pages 379-382

  Gunter, Wesley D ^a,b   Shepard, Jack D ^b   Foreman, Robert D ^b   Myers, Dean A ^b   Greenwood Van Meerveld, Beverley ^a,b  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

Author keywords

Anxiety; Irritable bowel syndrome; Rats; Visceral hyperalgesia

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANXIETY; ARTICLE; COLON DILATATION; CONTROLLED STUDY; DISEASE ASSOCIATION; GENETIC SUSCEPTIBILITY; HYPERALGESIA; INTESTINE INNERVATION; IRRITABLE COLON; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SENSITIZATION; VISCERAL PAIN;

EID: 0034131091     PISSN: 00319384     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0031-9384(99)00254-1     Document Type: Article

References (15)

1. Ritchie R. Pain from distention of the pelvic colon by inflating a balloon in the irritable colon syndrome. Gut. 14:1973;125-132.
2. Whitehead W.E., Holtkotter B., Enck P., Hoelzl R., Holmes K.D., Anthony J., Shabsin H.S., Schuster M.M. Tolerance for rectosigmoid distention in irritable bowel syndrome. Gastroenterology. 98:1990;1187-1192.
3. Lembo T., Fullerton S., Diehl D., Raeen H., Munakata J., Naliboff B., Mayer E.A. Symptom duration in patients with irritable bowel syndrome. Am J Gastroenterol. 91(5):1991;898-905.
4. Whitehead W.E., Crowell M.D., Robinson J.C., Heller B.R., Schuster M.M. Effects of stressful life events on bowel symptoms. subjects with irritable bowel syndrome compared with subjects without bowel dysfunction Gut. 33:1992;825-830.
5. Blanchard E.B., Scharff L., Schwarz S.P., Suls J.M., Barlow D.H. The role of anxiety and depression in the irritable bowel syndrome. Behav Res Theory. 28(5):1990;401-405.
6. Glowa J.R., Hansen C.T. Differences in responses to an acoustic startle stimulus among forty-six rat strains. Behav Genet. 24(1):1994;79-84.
7. Pare W.P. The performance of WKY rats on three tests of emotional behavior. Physiol Behav. 51:1992;1051-1056.
8. Ness T.J., Gebhart G.F. Colorectal distention as a noxious visceral stimulus. physiologic and pharmacologic characterization of pseudaffective reflexes in the rat Brain Res. 450:1988;153-169.
9. Langlois A., Pascaud X., Junien J.L., Dahl S.G., Riviere P.J. Response heterogeneity of 5-HT3 receptor antagonists in a rat visceral hypersensitivity model. Eur J Pharmacol. 318(1):1996;141-144.
10. Plourde V., St.-Pierre S., Quirion R. Calcitonin gene-related peptide in viscerosensitive response to colorectal distention in rats. Am J Physiol. 273(1pt. 1):1997;G191-G196.
11. Greenwood-Van Meerveld B., Tyler K.R., McDuff J., Plourde V. The role of spinal CGRP as a putative neurotransmitter in visceral hypersensitivity in visceral hypersensitivity. Gastroenterolology. 114(4pt. 2):1998;A757.
12. Monnikes H., Schmidt B.G., Raybould H.E., Tache Y. CRF in the paraventricular nucleus mediates gastric and colonic motor response in restraint stress. Am J Physiol. 262:1992;G137-G143.
13. Gue M., Del Rio-Lacheze C., Eutamene H., Theodorou V., Fioramonti J., Bueno L. Stress-induced visceral hypersensitivity to rectal distention in rats. role of CRF and mast cells Neurogastroenterol Mot. 9:1997;271-279.
14. Lechner S.M., Curtis A.L., Brons R., Valentino R.J. Locus coeruleus activation by colon distention. role of corticotropin-releasing factor and excitatory amino acids Brain Res. 756:1997;114-124.
15. Fukudo S, Nomura T, Hongo M. Impact of corticotropin-releasing hormone on gastrointestinal motility and adrenocorticotropic hormone in normal controls and patients with irritable bowel syndrome. Gut 1998; 845-9.