Analgesic effects of cannabinoid receptor agonist WIN55,212-2 in the nucleus cuneiformis in animal models of acute and inflammatory pain in rats

Brain Research

Volumn 1420, Issue , 2011, Pages 19-28

  Ebrahimzadeh, Mohammad ^a   Haghparast, Abbas ^a  

^a SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Antinociception; Cannabinoids; CB1 receptor; Formalin test; Nucleus cuneiformis; Rat; Tail flick test

Indexed keywords

1 (2,4 DICHLOROPHENYL) 5 (4 IODOPHENYL) 4 METHYL N (1 PIPERIDYL) 1H PYRAZOLE 3 CARBOXAMIDE; 2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; FORMALDEHYDE;

ANALGESIA; ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN NUCLEUS; CONTROLLED STUDY; CUNEIFORM NUCLEUS; DOSE RESPONSE; DRUG EFFICACY; DRUG INHIBITION; EXPERIMENTAL TEST; FORMALIN TEST; INFLAMMATORY PAIN; LOCOMOTION; MALE; MICROINJECTION; NEUROMODULATION; NOCICEPTION; NONHUMAN; PAIN; PRIORITY JOURNAL; RAT; TAIL FLICK TEST;

ANALGESICS; ANALYSIS OF VARIANCE; ANIMALS; AREA UNDER CURVE; BENZOXAZINES; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FORMALDEHYDE; HOT TEMPERATURE; INFLAMMATION; MALE; MEDULLA OBLONGATA; MICROINJECTIONS; MORPHOLINES; MOTOR ACTIVITY; NAPHTHALENES; PAIN; PAIN MEASUREMENT; PIPERIDINES; PYRAZOLES; RATS; RATS, WISTAR; RECEPTORS, CANNABINOID; TIME FACTORS;

ANIMALIA; RATTUS;

EID: 80055053848     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2011.08.028     Document Type: Article

References (30)

1. J.F. Bernard, M. Peschanski, and J.M. Besson Afferents and efferents of the rat cuneiformis nucleus: an anatomical study with reference to pain transmission Brain Res. 490 1989 181 185 (Pubitemid 19154980)
2. A.S. Bloom, W.L. Dewey, L.S. Harris, and K.K. Brosius 9-nor-9beta-hydroxyhexahydrocannabinol, a cannabinoid with potent antinociceptive activity: comparisons with morphine J. Pharmacol. Exp. Ther. 200 1977 263 270 (Pubitemid 8037481)
3. T.J. Coderre, M.E. Fundytus, J.E. McKenna, S. Dalal, and R. Melzack The formalin test: a validation of the weighted-scores method of behavioural pain rating Pain 54 1993 43 50 (Pubitemid 23200570)
4. D. Dubuisson, and S.G. Dennis The formalin test: a quantitative study of the analgesic effects of morphine, meperidine, and brain stem stimulation in rats and cats Pain 4 1978 161 174 (Pubitemid 8234766)
5. M. Gioia, and R. Bianchi The cytoarchitecture of the nucleus cuneiformis, A Nissl and Golgi study J. Anat. 155 1987 165 176 (Pubitemid 18007572)
6. A. Haghparast, and L. Ahmad-Molaei Effects of electrolytic lesion of dorsolateral periaqueductal gray on analgesic response of morphine microinjected into the nucleus cuneiformis in rat Neurosci. Lett. 451 2009 165 169
7. A. Haghparast, I.P. Gheitasi, and R. Lashgari Involvement of glutamatergic receptors in the nucleus cuneiformis in modulating morphine-induced antinociception in rats Eur. J. Pain 11 2007 855 862 (Pubitemid 47321240)
8. A. Haghparast, A. Soltani-Hekmat, A. Khani, and A. Komaki Role of glutamatergic receptors located in the nucleus raphe magnus on antinociceptive effect of morphine microinjected into the nucleus cuneiformis of rat Neurosci. Lett. 427 2007 44 49 (Pubitemid 47599792)
9. A. Haghparast, M. Ordikhani-Seyedlar, and M. Ziaei Electrolytic lesion of the nucleus raphe magnus reduced the antinociceptive effects of bilateral morphine microinjected into the nucleus cuneiformis in rats Neurosci. Lett. 438 2008 351 355
10. A. Haghparast, N. Naderi, A. Khani, R. Lashgari, and F. Motamedi Formalin-induced differential activation of nucleus cuneiformis neurons in the rat: an electrophysiological study J. Pain 11 2010 32 43
11. P. Hasanein, M. Parviz, M. Keshavarz, and K. Javanmardi CB1 receptor activation in the basolateral amygdala produces antinociception in animal models of acute and tonic nociception Clin. Exp. Pharmacol. Physiol. 34 2007 439 449 (Pubitemid 46494468)
12. E.L. Heinzen, and G.M. Pollack Pharmacodynamics of morphine-induced neuronal nitric oxide production and antinociceptive tolerance development Brain Res. 1023 2004 175 184 (Pubitemid 39221420)
13. H. Herbert, and C.B. Saper Organization of medullary adrenergic and noradrenergic projections to the periaqueductal gray matter in the rat J. Comp. Neurol. 315 1992 34 52
14. A.G. Hohmann, R.L. Suplita, N.M. Bolton, M.H. Neely, D. Fegley, and R. Mangieri An endocannabinoid mechanism for stress-induced analgesia Nature 435 2005 1108 1112 (Pubitemid 40910518)
15. J.J. Jacob, K. Ramabadran, and M. Campos-Medeiros A pharmacological analysis of levonantradol antinociception in mice J. Clin. Pharmacol. 21 1981 327 333 Suppl.
16. A.H. Lichtman, S.A. Cook, and B.R. Martin Investigation of brain sites mediating cannabinoid-induced antinociception in rats: evidence supporting periaqueductal gray involvement J. Pharmacol. Exp. Ther. 276 1996 585 593
17. B.H. Manning, and K.B.J. Franklin Morphine analgesia in the formalin test: reversal by microinjection of quaternary naloxone into the posterior hypothalamic area or periaqueductal gray Behav. Brain Res. 92 1998 97 102 (Pubitemid 28179611)
18. W.J. Martin, S.L. Patrick, P.O. Coffin, K. Tsou, and J.M. Walker An examination of the central sites of action of cannabinoid-induced antinociception in the rat Life Sci. 56 1995 2103 2109
19. W.J. Martin, K. Tsou, and J.M. Walker Cannabinoid receptor-mediated inhibition of the rat tail-flick reflex after microinjection into the rostral ventromedial medulla Neurosci. Lett. 242 1998 33 36 (Pubitemid 28122702)
20. W.J. Martin, P.O. Coffin, E. Attias, M. Balinsky, K. Tsou, and J.M. Walker Anatomical basis for cannabinoid-induced antinociception as revealed by intracerebral microinjections Brain Res. 822 1999 237 242 (Pubitemid 29222848)
21. I.D. Meng, and J.P. Johansen Antinociception and modulation of rostral ventromedial medulla neuronal activity by local microinfusion of a cannabinoid receptor agonist Neuroscience 124 2004 685 693 (Pubitemid 38251333)
22. I.D. Meng, B.H. Manning, W.J. Martin, and H.L. Fields An analgesia circuit activated by cannabinoids Nature 395 1998 381 383 (Pubitemid 28450687)
23. R. Monhemius, J. Azami, D.L. Green, and M.H.T. Roberts CB1 receptor mediated analgesia from the nucleus reticularis gigantocellularis pars alpha is activated in an animal model of neuropathic pain Brain Res. 908 2001 67 74 (Pubitemid 32703662)
24. E. Palazzo, I. Marabese, V. De Novellis, P. Oliva, F. Rossi, and L. Berrino Metabotropic and NMDA glutamate receptors participate in the cannabinoid-induced antinociception Neuropharmacology 40 2001 319 326 (Pubitemid 32144710)
25. G. Paxinos, and C.R. Watson The Rat Brain in Stereotaxic Coordinates sixth ed. 2007 Elsevier Academic Press San Diego
26. M. Rezvanipour, A. Haghparast, and H. Millan The role of GABA A receptor inhibitor on morphine antinociception action in cuneiformis nucleus Int. J. Pharmacol. 2 2006 400 405 (Pubitemid 44613205)
27. R.L. Suplita, J.N. Farthing, T. Gutierrez, and A.G. Hohmann Inhibition of fatty-acid amide hydrolase enhances cannabinoid stress-induced analgesia: sites of action in the dorsolateral periaqueductal gray and rostral ventromedial medulla Neuropharmacology 49 2005 1201 1209 (Pubitemid 41608644)
28. 2 receptor Science 310 2005 329 332 (Pubitemid 41457202)
29. J.M. Walker, S.M. Huang, N.M. Strangman, K. Tsou, and M. Sañudo-Peña Pain modulation by release of the endogenous cannabinoid anandamide Proc. Natl. Acad. Sci. USA 96 1999 12198 12203 (Pubitemid 29502881)
30. K. Wegner, K.A. Horais, N.A. Tozier, M.L. Rathbun, Y. Shtaerman, and T.L. Yaksh Development of a canine nociceptive thermal escape model J. Neurosci. methods 168 2008 88 97