Acute exposure of methylglyoxal leads to activation of KATP channels expressed in HEK293 cells

Acta Pharmacologica Sinica

Volumn 35, Issue 1, 2014, Pages 58-64

  Yang, Yang ^a,b   Konduru, Anuhya S ^a   Cui, Ningren ^a   Yu, Lei ^a   Trower, Timothy C ^a   Shi, Weiwei ^a   Shi, Yun ^a   Jiang, Chun ^a  

^a GEORGIA STATE UNIVERSITY   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

ATP sensitive potassium channel; diabetes; Kir6.1; Kir6.2; Kir6.2 36; methylglyoxal; reactive carbonyl species; sulfonylurea receptor; vascular dysfunction

Indexed keywords

GLIBENCLAMIDE; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR6.1; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR6.2; ISOPROTEIN; METHYLGLYOXAL; PINACIDIL;

ARTICLE; COMPUTER PROGRAM; EXPOSURE; HUMAN; HUMAN CELL; INSIDE OUT PATCH CLAMP; NUCLEOTIDE SEQUENCE; POTASSIUM CONDUCTANCE; PROTEIN EXPRESSION; WHOLE CELL;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; HEK293 CELLS; HUMANS; KATP CHANNELS; MICE; PYRUVALDEHYDE; RATS; TIME FACTORS;

EID: 84891813904     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2013.122     Document Type: Article

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