S-Glutathionylation underscores the modulation of the heteromeric Kir4.1-Kir5.1 channel in oxidative stress

Journal of Physiology

Volumn 590, Issue 21, 2012, Pages 5335-5348

  Jin, Xin ^a   Yu, Lei ^a   Wu, Yang ^a   Zhang, Shuang ^a   Shi, Zhenda ^a   Chen, Xianfeng ^a,b   Yang, Yang ^a   Zhang, Xiaoli ^a   Jiang, Chun ^a  

^a GEORGIA STATE UNIVERSITY   (United States)

^b NATIONAL CENTER FOR IMMUNIZATION AND RESPIRATORY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIAMIDE; GLUTATHIONE; HYDROGEN PEROXIDE; POTASSIUM CHANNEL; POTASSIUM CHANNEL KIR4.1; POTASSIUM CHANNEL KIR5.1; PYRIDINE DERIVATIVE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRUCTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME INHIBITION; ENZYME REGULATION; GLUTATHIONYLATION; HUMAN; HUMAN CELL; MOLECULAR MECHANICS; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN MODIFICATION; PROTEIN STRUCTURE; PROTEIN TARGETING; RAT; SITE DIRECTED MUTAGENESIS;

GLUTATHIONE; HEK293 CELLS; HUMANS; OXIDANTS; OXIDATIVE STRESS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PROTEIN CONFORMATION; SULFHYDRYL COMPOUNDS;

EID: 84868109836     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2012.236885     Document Type: Article

References (36)

1. Bond CT, Pessia M, Xia XM, Lagrutta A, Kavanaugh MP & Adelman JP (1994). Cloning and expression of a family of inward rectifier potassium channels. Receptors Channels 2, 183-191.
2. Butt AM & Kalsi A (2006). Inwardly rectifying potassium channels (Kir) in central nervous system glia: a special role for Kir4.1 in glial functions. J Cell Mol Med 10, 33-44.
3. Casamassima M, D'Adamo MC, Pessia M & Tucker SJ (2003). Identification of a heteromeric interaction that influences the rectification, gating, and pH sensitivity of Kir4.1/Kir5.1 potassium channels. J Biol Chem 278, 43533-43540.
4. CO2 at physiological levels. J Cell Physiol 189, 229-236.
5. Doyle DA (2004). Structural changes during ion channel gating. Trends Neurosci 27, 298-302.
6. Feldman EL (2003). Oxidative stress and diabetic neuropathy: a new understanding of an old problem. J Clin Invest 111, 431-433.
7. Giacco F & Brownlee M (2010). Oxidative stress and diabetic complications. Circ Res 107, 1058-1070.
8. Griendling KK & FitzGerald GA (2003). Oxidative stress and cardiovascular injury: Part II: animal and human studies. Circulation 108, 2034-2040.
9. + channel subunits, Kir4.1 and Kir5.1, in brain astrocytes. J Biol Chem 279, 44065-44073.
10. Hibino H, Inanobe A, Furutani K, Murakami S, Findlay I & Kurachi Y (2010). Inwardly rectifying potassium channels: their structure, function, and physiological roles. Physiol Rev 90, 291-366.
11. Jager RD, Mieler WF & Miller JW (2008). Age-related macular degeneration. N Engl J Med 358, 2606-2617.
12. Kuo A, Gulbis JM, Antcliff JF, Rahman T, Lowe ED, Zimmer J et al. (2003). Crystal structure of the potassium channel KirBac1.1 in the closed state. Science 300, 1922-1926.
13. + channel in the basolateral membrane of mouse renal collecting duct principal cells. Am J Physiol Renal Physiol 294, F1398-1407.
14. Lin MT & Beal MF (2006). Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. Nature 443, 787-795.
15. Miller YI, Choi SH, Wiesner P, Fang L, Harkewicz R, Hartvigsen K et al. (2011). Oxidation-specific epitopes are danger-associated molecular patterns recognized by pattern recognition receptors of innate immunity. Circ Res 108, 235-248.
16. Nishida M, Cadene M, Chait BT & MacKinnon R (2007). Crystal structure of a Kir3.1-prokaryotic Kir channel chimera. EMBO J 26, 4005-4015.
17. Pessia M, Imbrici P, D'Adamo MC, Salvatore L & Tucker SJ (2001). Differential pH sensitivity of Kir4.1 and Kir4.2 potassium channels and their modulation by heteropolymerisation with Kir5.1. J Physiol 532, 359-367.
18. Rojas A, Cui N, Su J, Yang L, Muhumuza JP & Jiang C (2007). Protein kinase C dependent inhibition of the heteromeric Kir4.1-Kir5.1 channel. Biochim Biophys Acta 1768, 2030-2042.
19. Rojas A, Su J, Yang L, Lee M, Cui N, Zhang X et al. (2008). Modulation of the heteromeric Kir4.1-Kir5.1 channel by multiple neurotransmitters via Gαq-coupled receptors. J Cell Physiol 214, 84-95.
20. Schiffrin EL, Lipman ML & Mann JF (2007). Chronic kidney disease: effects on the cardiovascular system. Circulation 116, 85-97.
21. Shang L, Ranson SV & Tucker SJ (2009). Kir5.1 underlies long-lived subconductance levels in heteromeric Kir4.1/Kir5.1 channels from Xenopus tropicalis. Biochem Biophys Res Commun 388, 501-505.
22. Shi Y, Wu Z, Cui N, Shi W, Yang Y, Zhang X et al. (2007). PKA phosphorylation of SUR2B subunit underscores vascular KATP channel activation by β-adrenergic receptors. Am J Physiol Regul Integr Comp Physiol 293, R1205-1214.
23. + channel by heteromeric subunit assembly of Kir5.1 with Kir4.1. J Physiol 525, 587-592.
24. Wang R, Zhang X, Cui N, Wu J, Piao H, Wang X et al. (2007). Subunit-stoichiometric evidence for kir6.2 channel gating, ATP binding, and binding-gating coupling. Mol Pharmacol 71, 1646-1656.
25. + by inhibition of a Kir4.1-Kir5.1-like current and may contribute to chemoreception by a purinergic mechanism. J Neurophysiol 104, 3042-3052.
26. Wu S, Skolnick J & Zhang Y (2007). Ab initio modeling of small proteins by iterative TASSER simulations. BMC Biol 5, 17.
27. Xu H, Cui N, Yang Z, Qu Z & Jiang C (2000). Modulation of Kir4.1 and Kir5.1 by hypercapnia and intracellular acidosis. J Physiol 524, 725-735.
28. ATP channel gating by S-glutathionylation. J Biol Chem 286, 9298-9307.
29. ATP channels by S-glutathionylation. J Biol Chem 285, 38641-38648.
30. Yang Z & Jiang C (1999). Opposite effects of pH on open-state probability and single channel conductance of Kir4.1 channels. J Physiol 520, 921-927.
31. 2 and pH. J Gen Physiol 116, 33-45.
32. Yoshida T, Inoue R, Morii T, Takahashi N, Yamamoto S, Hara Y, Tominaga M, Shimizu S, Sato Y & Mori Y (2006). Nitric oxide activates TRP channels by cysteine S-nitrosylation. Nat Chem Biol 2, 596-607.
33. Yu L, Jin X, Yang Y, Cui N & Jiang - (2011). Rosiglitazone inhibits vascular KATP channels and coronary vasodilation produced by isoprenaline. Br J Pharmacol 164, 2064-2072.
34. 2 chemosensitivity in a mouse model of Rett syndrome. Am J Physiol Cell Physiol 301, C729-738.
35. Zhang Y (2008). I-TASSER server for protein 3D structure prediction. BMC Bioinformatics 9, 40.
36. Zhang Y (2007). Template-based modeling and free modeling by I-TASSER in CASP7. Proteins 69(Suppl 8), 108-117.