Prolonged exposure to methylglyoxal causes disruption of vascular KATP channel by mRNA instability

American Journal of Physiology - Cell Physiology

Volumn 303, Issue 10, 2012, Pages

  Yang, Yang ^a   Li, Shanshan ^a   Konduru, Anuhya S ^a   Zhang, Shuang ^a,b   Trower, Timothy C ^a   Shi, Weiwei ^a   Cui, Ningren ^a   Yu, Lei ^a,b   Wang, Yali ^b   Zhu, Daling ^b   Jiang, Chun ^a  

^a GEORGIA STATE UNIVERSITY   (United States)

^b HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

ATP sensitive potassium channel; Diabetes; Metabolites; Vascular complications; Vascular smooth muscles

Indexed keywords

ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; DACTINOMYCIN; GLIBENCLAMIDE; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR6.1; ISOPROTEIN; LUCIFERASE; MESSENGER RNA; METHYLGLYOXAL; PROTEIN SUR2B; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL WALL; CONTROLLED STUDY; DIABETES MELLITUS; ENZYME ASSAY; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; MEMBRANE DAMAGE; MESENTERIC ARTERY; MOLECULAR STABILITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; CLONING, MOLECULAR; GENE EXPRESSION REGULATION; HEK293 CELLS; HUMANS; KATP CHANNELS; MESENTERIC ARTERIES; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PYRUVALDEHYDE; RATS; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, DRUG; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA STABILITY; RNA, MESSENGER; VASOCONSTRICTION;

EID: 84869203668     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00020.2012     Document Type: Article

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