Diabetes mellitus impairs vasodilation to hypoxia in human coronary arterioles: Reduced activity of ATP-sensitive potassium channels

Circulation Research

Volumn 92, Issue 2, 2003, Pages 151-158

  Miura, Hiroto ^a,d   Wachtel, Ruth E ^b,c   Loberiza Jr , Fausto R ^d   Saito, Takashi ^e   Miura, Mamoru ^e   Nicolosi, Alfred C ^d   Gutterman, David D ^a,d  

^a CLEMENT J ZABLOCKI VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c UNIVERSITY OF IOWA   (United States)

^d MEDICAL COLLEGE OF WISCONSIN   (United States)

^e AKITA UNIVERSITY   (Japan)

Author keywords

ATP sensitive potassium channels; Coronary microcirculation; Diabetes mellitus; Human; Hypoxia

Indexed keywords

ADENOSINE TRIPHOSPHATE; APRIKALIM; BRADYKININ; GLIBENCLAMIDE; MESSENGER RNA; NITROPRUSSIDE SODIUM; POTASSIUM CHANNEL; POTASSIUM CHANNEL AFFECTING AGENT;

ADULT; AGED; ARTERIOLE; ARTICLE; BLOOD VESSEL TONE; CARDIOVASCULAR DISEASE; CONTROLLED STUDY; CORONARY ARTERY; DIABETES MELLITUS; FEMALE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; HYPERPOLARIZATION; HYPOXIA; IMMUNOHISTOCHEMISTRY; INSULIN DEPENDENT DIABETES MELLITUS; MALE; MEMBRANE POTENTIAL; MEMBRANE STEADY POTENTIAL; MORBIDITY; MORTALITY; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE; VASODILATATION; VASOMOTOR REFLEX;

ADENOSINE TRIPHOSPHATE; AGE FACTORS; ANOXIA; ARTERIOLES; BRADYKININ; CORONARY VESSELS; DIABETES MELLITUS; FEMALE; GLYBURIDE; HUMANS; MALE; MEMBRANE POTENTIALS; MICROCIRCULATION; MIDDLE AGED; MUSCLE, SMOOTH, VASCULAR; NITRIC OXIDE DONORS; PICOLINES; POTASSIUM CHANNELS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PYRANS; RISK FACTORS; RNA, MESSENGER; SEX FACTORS; VASODILATION; VASODILATOR AGENTS;

EID: 0037423556     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000052671.53256.49     Document Type: Article

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