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Volumn 4, Issue 1, 2014, Pages

Induction of tolerance through mixed chimerism

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN;

EID: 84891811304     PISSN: None     EISSN: 21571422     Source Type: Journal    
DOI: 10.1101/cshperspect.a015529     Document Type: Article
Times cited : (113)

References (139)
  • 1
    • 0344553377 scopus 로고    scopus 로고
    • Heterologous immunity: An overlooked barrier to tolerance
    • Adams A.B., Pearson TC, Larsen CP. 2003a. Heterologous immunity: An overlooked barrier to tolerance. Immunol Rev 196: 147-160.
    • (2003) Immunol Rev , vol.196 , pp. 147-160
    • Adams, A.B.1    Pearson, T.C.2    Larsen, C.P.3
  • 5
    • 0032521267 scopus 로고    scopus 로고
    • Bone marrow transplantation induces either clonal deletion or infectious tolerance depending on the dose
    • Bemelman F., Honey K, Adams E, Cobbold S, Waldmann H. 1998. Bone marrow transplantation induces either clonal deletion or infectious tolerance depending on the dose. J Immunol 160: 2645-2648.
    • (1998) J Immunol , vol.160 , pp. 2645-2648
    • Bemelman, F.1    Honey, K.2    Adams, E.3    Cobbold, S.4    Waldmann, H.5
  • 8
    • 0024429365 scopus 로고
    • Graft failure after T-celldepleted human leukocyte antigen identical marrow transplants for leukemia: II. In vitro analyses of host effector mechanisms
    • Bordignon C., Keever CA, Small TN, Flomenberg N, Dupont B, O'Reilly RJ, KernanNA. 1989. Graft failure after T-celldepleted human leukocyte antigen identical marrow transplants for leukemia: II. In vitro analyses of host effector mechanisms. Blood 74: 2237-2243.
    • (1989) Blood , vol.74 , pp. 2237-2243
    • Bordignon, C.1    Keever, C.A.2    Small, T.N.3    Flomenberg, N.4    Dupont, B.5    O'Reilly, R.J.6    Kernan, N.A.7
  • 11
    • 33746908248 scopus 로고    scopus 로고
    • Host MHC class II+ antigenpresenting cells and CD4 cells are required for CD8-mediated graft-versus-leukemia responses following delayed donor leukocyte infusions
    • Chakraverty R., Eom HS, Sachs J, Buchli J, Cotter P, Hsu R, Zhao G., Sykes M. 2006b. Host MHC class II+ antigenpresenting cells and CD4 cells are required for CD8-mediated graft-versus-leukemia responses following delayed donor leukocyte infusions. Blood 108: 2106-2113.
    • (2006) Blood , vol.108 , pp. 2106-2113
    • Chakraverty, R.1    Eom, H.S.2    Sachs, J.3    Buchli, J.4    Cotter, P.5    Hsu, R.6    Zhao, G.7    Sykes, M.8
  • 13
    • 0025522584 scopus 로고
    • Reprogramming the immune system for tolerance with monoclonal antibodies
    • Cobbold S.P., Qin S, Waldmann H. 1990. Reprogramming the immune system for tolerance with monoclonal antibodies. Sem Immunol 2: 377-387.
    • (1990) Sem Immunol , vol.2 , pp. 377-387
    • Cobbold, S.P.1    Qin, S.2    Waldmann, H.3
  • 14
    • 1842472899 scopus 로고    scopus 로고
    • Mixed chimerism and transplantation tolerance
    • Cosimi A.B., Sachs DH. 2004. Mixed chimerism and transplantation tolerance. Transplantation 77: 943-946.
    • (2004) Transplantation , vol.77 , pp. 943-946
    • Cosimi, A.B.1    Sachs, D.H.2
  • 15
    • 0024398476 scopus 로고
    • A model for T cell receptor and MHC/peptide interaction
    • Davis M.M., Bjorkman PJ. 1990. A model for T cell receptor and MHC/peptide interaction. Adv Exp Med Biol 254: 13-16.
    • (1990) Adv Exp Med Biol , vol.254 , pp. 13-16
    • Davis, M.M.1    Bjorkman, P.J.2
  • 16
    • 13444310503 scopus 로고    scopus 로고
    • Anti-tumor response despite loss of donor chimerism in patients treated with nonmyeloablative conditioning and allogeneic stem cell transplantation
    • Dey B.R., Mcafee S, Colby C, Cieply K, Caron M, Saidman S, Preffer F., Shaffer J, Tarbell N, Sackstein R, et al. 2005. Anti-tumor response despite loss of donor chimerism in patients treated with nonmyeloablative conditioning and allogeneic stem cell transplantation. Br J Haematol 128: 351-359.
    • (2005) Br J Haematol , vol.128 , pp. 351-359
    • Dey, B.R.1    McAfee, S.2    Colby, C.3    Cieply, K.4    Caron, M.5    Saidman, S.6    Preffer, F.7    Shaffer, J.8    Tarbell, N.9    Sackstein, R.10
  • 17
    • 21244483043 scopus 로고    scopus 로고
    • Roles of deletion and regulation in creating mixed chimerism and allograft tolerance using a nonlymphoablative irradiation-free protocol
    • Domenig C., Sanchez-Fueyo A, Kurtz J, Alexopoulos AP, Mariat C., Sykes M, Strom TB, Zheng XX. 2005. Roles of deletion and regulation in creating mixed chimerism and allograft tolerance using a nonlymphoablative irradiation-free protocol. J Immunol 175: 51-60.
    • (2005) J Immunol , vol.175 , pp. 51-60
    • Domenig, C.1    Sanchez-Fueyo, A.2    Kurtz, J.3    Alexopoulos, A.P.4    Mariat, C.5    Sykes, M.6    Strom, T.B.7    Zheng, X.X.8
  • 18
    • 0037378671 scopus 로고    scopus 로고
    • Two developmentally distinct populations of dendritic cells inhabit the adult mouse thymus: Demonstration by differential importation of hematogenous precursors under steady state conditions
    • Donskoy E., Goldschneider I. 2003. Two developmentally distinct populations of dendritic cells inhabit the adult mouse thymus: Demonstration by differential importation of hematogenous precursors under steady state conditions. J Immunol 170: 3514-3521.
    • (2003) J Immunol , vol.170 , pp. 3514-3521
    • Donskoy, E.1    Goldschneider, I.2
  • 20
    • 47949126592 scopus 로고    scopus 로고
    • Alloreactive CD8 T cell tolerance requires recipient B cells, dendritic cells and MHC class II
    • Fehr T., Haspot F, Mollov J, Chittenden M, Hogan T, Sykes M. 2008. Alloreactive CD8 T cell tolerance requires recipient B cells, dendritic cells and MHC class II. J Immunol 181: 165-173.
    • (2008) J Immunol , vol.181 , pp. 165-173
    • Fehr, T.1    Haspot, F.2    Mollov, J.3    Chittenden, M.4    Hogan, T.5    Sykes, M.6
  • 21
    • 77949536177 scopus 로고    scopus 로고
    • A CD8 T cell-intrinsic role for the calcineurin-NFAT pathway for tolerance induction in vivo
    • Fehr T., Lucas CL, Kurtz J, Onoe T, Zhao G, Hogan T, Vallot C, Rao A, Sykes M. 2010. A CD8 T cell-intrinsic role for the calcineurin-NFAT pathway for tolerance induction in vivo. Blood 115: 1280-1287.
    • (2010) Blood , vol.115 , pp. 1280-1287
    • Fehr, T.1    Lucas, C.L.2    Kurtz, J.3    Onoe, T.4    Zhao, G.5    Hogan, T.6    Vallot, C.7    Rao, A.8    Sykes, M.9
  • 22
    • 0025634104 scopus 로고
    • Bone marrow-allograft rejection by T lymphocytes recognizing a single amino acid difference in HLA-B44
    • Fleischhauer K., KernanNA, O'Reilly RJ, Dupont B, Yang SY. 1990. Bone marrow-allograft rejection by T lymphocytes recognizing a single amino acid difference in HLA-B44. New Engl J Med 323: 1818-1822.
    • (1990) New Engl J Med , vol.323 , pp. 1818-1822
    • Fleischhauer, K.1    Kernan, N.A.2    O'Reilly, R.J.3    Dupont, B.4    Yang, S.Y.5
  • 26
    • 0025729833 scopus 로고
    • Induction of kidney transplantation tolerance across MHC barriers by bone marrow transplantation in miniature swine
    • Guzzetta P.C., Sundt TM, Suzuki T, Mixon A, Rosengard BR, Sachs DH. 1991. Induction of kidney transplantation tolerance across MHC barriers by bone marrow transplantation in miniature swine. Transplantation 51: 862-866.
    • (1991) Transplantation , vol.51 , pp. 862-866
    • Guzzetta, P.C.1    Sundt, T.M.2    Suzuki, T.3    Mixon, A.4    Rosengard, B.R.5    Sachs, D.H.6
  • 28
    • 85137904331 scopus 로고    scopus 로고
    • Transplantation in miniature swine
    • In (ed. McAnulty PA), Taylor & Francis, London, 2011
    • Hanekamp J.S., Duran-Struuck R, Sachs DH. 2011. Transplantation in miniature swine. In The minipig in biomedical research (ed. McAnulty PA), pp. 357-372. Taylor & Francis, London, 2011.
    • (2011) The minipig in biomedical research , pp. 357-372
    • Hanekamp, J.S.1    Duran-Struuck, R.2    Sachs, D.H.3
  • 29
    • 52649129667 scopus 로고    scopus 로고
    • Peripheral deletional tolerance of alloreactive CD8 but not CD4 cells is dependent on the PD-1/PD-L1 pathway
    • Haspot F., Fehr T, Gibbons C, Zhao G, Hogan T, Honjo T, Freeman G.J., Sykes M. 2008. Peripheral deletional tolerance of alloreactive CD8 but not CD4 cells is dependent on the PD-1/PD-L1 pathway. Blood 112: 2149-2155.
    • (2008) Blood , vol.112 , pp. 2149-2155
    • Haspot, F.1    Fehr, T.2    Gibbons, C.3    Zhao, G.4    Hogan, T.5    Honjo, T.6    Freeman, G.J.7    Sykes, M.8
  • 31
    • 0034124915 scopus 로고    scopus 로고
    • The role of the thymus in immune reconstitution in aging, bone marrow transplantation, and HIV-1 infection
    • Haynes B.F., Markert ML, Sempowski GD, Patel DD, Hale LP. 2000. The role of the thymus in immune reconstitution in aging, bone marrow transplantation, and HIV-1 infection. Annu Rev Immunol 18: 529-560.
    • (2000) Annu Rev Immunol , vol.18 , pp. 529-560
    • Haynes, B.F.1    Markert, M.L.2    Sempowski, G.D.3    Patel, D.D.4    Hale, L.P.5
  • 32
    • 0028560026 scopus 로고
    • Renal transplantation without immunosuppression in a host with tolerance induced by allogeneic bone marrow transplantation
    • Helg C., Chapuis B, Bolle JF, Morel P, Salomon D, Roux E, Antonioli V., Jeannet M, Leski M. 1994. Renal transplantation without immunosuppression in a host with tolerance induced by allogeneic bone marrow transplantation. Transplantation 58: 1420-1422.
    • (1994) Transplantation , vol.58 , pp. 1420-1422
    • Helg, C.1    Chapuis, B.2    Bolle, J.F.3    Morel, P.4    Salomon, D.5    Roux, E.6    Antonioli, V.7    Jeannet, M.8    Leski, M.9
  • 36
  • 37
    • 0021251825 scopus 로고
    • Reconstitution with syngeneic plus allogeneic or xenogeneic bone marrow leads to specific acceptance of allografts or xenografts
    • Ildstad S.T., Sachs DH. 1984. Reconstitution with syngeneic plus allogeneic or xenogeneic bone marrow leads to specific acceptance of allografts or xenografts. Nature 307: 168-170.
    • (1984) Nature , vol.307 , pp. 168-170
    • Ildstad, S.T.1    Sachs, D.H.2
  • 38
    • 0021845739 scopus 로고
    • Characterization of mixed allogeneic chimeras. Immunocompetence, in vitro reactivity, and genetic specificity of tolerance
    • Ildstad S.T., Wren SM, Bluestone JA, Barbieri SA, Sachs DH. 1985. Characterization of mixed allogeneic chimeras. Immunocompetence, in vitro reactivity, and genetic specificity of tolerance. J Exp Med 162: 231-244.
    • (1985) J Exp Med , vol.162 , pp. 231-244
    • Ildstad, S.T.1    Wren, S.M.2    Bluestone, J.A.3    Barbieri, S.A.4    Sachs, D.H.5
  • 39
    • 0022638798 scopus 로고
    • Effect of selective T cell depletion of host and/or donor bone marrow on lymphopoietic repopulation, tolerance, and graft-vs-host disease in mixed allogeneic chimeras (B10 + B10. D2! B10)
    • Ildstad ST, Wren SM, Bluestone JA, Barbieri SA, StephanyD, Sachs DH. 1986. Effect of selective T cell depletion of host and/or donor bone marrow on lymphopoietic repopulation, tolerance, and graft-vs-host disease in mixed allogeneic chimeras (B10 + B10. D2! B10). J Immunol 136: 28-33.
    • (1986) J Immunol , vol.136 , pp. 28-33
    • Ildstad, S.T.1    Wren, S.M.2    Bluestone, J.A.3    Barbieri, S.A.4    Stephany, D.5    Sachs, D.H.6
  • 40
    • 0035284740 scopus 로고    scopus 로고
    • CD4 T cell-mediated alloresistance to fully MHC-mismatched allogeneic bone marrow engraftment is dependent on CD40-CD40 L interactions, and lasting T cell tolerance is induced by bone marrow transplantation with initial blockade of this pathway
    • Ito H., Kurtz J, Shaffer J, Sykes M. 2001. CD4 T cell-mediated alloresistance to fully MHC-mismatched allogeneic bone marrow engraftment is dependent on CD40-CD40 L interactions, and lasting T cell tolerance is induced by bone marrow transplantation with initial blockade of this pathway. J Immunol 166: 2970-2981.
    • (2001) J Immunol , vol.166 , pp. 2970-2981
    • Ito, H.1    Kurtz, J.2    Shaffer, J.3    Sykes, M.4
  • 41
    • 23444459237 scopus 로고
    • Tolerance to an HLA-B, DR disparate kidney allograft after bone-marrow transplantation from same donor
    • Jacobsen N., Taaning E, Ladefoged J, Kristensen JK, Pedersen FK. 1994. Tolerance to an HLA-B, DR disparate kidney allograft after bone-marrow transplantation from same donor. Lancet 343: 800.
    • (1994) Lancet , vol.343 , pp. 800
    • Jacobsen, N.1    Taaning, E.2    Ladefoged, J.3    Kristensen, J.K.4    Pedersen, F.K.5
  • 43
    • 0028006820 scopus 로고
    • Phenotypic characterization of a novel bone marrow-derived cell that facilitates engraftment of allogeneic bone marrow stem cells
    • Kaufman C.L., Colson YL, Wren SM, Watkins S, Simmons RL, Ildstad ST. 1994. Phenotypic characterization of a novel bone marrow-derived cell that facilitates engraftment of allogeneic bone marrow stem cells. Blood 84: 2436-2446.
    • (1994) Blood , vol.84 , pp. 2436-2446
    • Kaufman, C.L.1    Colson, Y.L.2    Wren, S.M.3    Watkins, S.4    Simmons, R.L.5    Ildstad, S.T.6
  • 46
    • 0033965079 scopus 로고    scopus 로고
    • Thromboembolic complications after treatment with monoclonal antibody against CD40 ligand [letter]
    • Kawai T., Andrews D, Colvin RB, Sachs DH, Cosimi AB. 2000. Thromboembolic complications after treatment with monoclonal antibody against CD40 ligand [letter]. Nat Med 6: 114.
    • (2000) Nat Med , vol.6 , pp. 114
    • Kawai, T.1    Andrews, D.2    Colvin, R.B.3    Sachs, D.H.4    Cosimi, A.B.5
  • 47
    • 0034897889 scopus 로고    scopus 로고
    • Long-term islet allograft function in the absence of chronic immunosuppression: A case report of a nonhuman primate previously made tolerant to a renal allograft from the same donor
    • Kawai T., Sogawa H, Koulmanda M, Smith RN, O'Neil JJ, Wee S.L., Boskovic S, Sykes M, Colvin RB, Sachs DH, et al. 2001. Long-term islet allograft function in the absence of chronic immunosuppression: A case report of a nonhuman primate previously made tolerant to a renal allograft from the same donor. Transplantation 72: 351-354.
    • (2001) Transplantation , vol.72 , pp. 351-354
    • Kawai, T.1    Sogawa, H.2    Koulmanda, M.3    Smith, R.N.4    O'Neil, J.J.5    Wee, S.L.6    Boskovic, S.7    Sykes, M.8    Colvin, R.B.9    Sachs, D.H.10
  • 51
    • 80051790231 scopus 로고    scopus 로고
    • Preclinical and clinical studies on the induction of renal allograft tolerance through transient mixed chimerism
    • Kawai T., Cosimi AB, Sachs DH. 2011. Preclinical and clinical studies on the induction of renal allograft tolerance through transient mixed chimerism. Curr Opin Organ Transplant 16: 366-371.
    • (2011) Curr Opin Organ Transplant , vol.16 , pp. 366-371
    • Kawai, T.1    Cosimi, A.B.2    Sachs, D.H.3
  • 52
    • 84863200538 scopus 로고    scopus 로고
    • Cooking up tolerance: Has a new recipe been created?
    • Kean L.S., Blazar BR. 2012. Cooking up tolerance: Has a new recipe been created? Am J Transplant 12: 1667-1669.
    • (2012) Am J Transplant , vol.12 , pp. 1667-1669
    • Kean, L.S.1    Blazar, B.R.2
  • 53
    • 0023189896 scopus 로고
    • Graft rejection in recipients of T-cell-depleted HLA-nonidentical marrow transplants for leukemia
    • Kernan N.A., Flomenberg N, Dupont B, O'Reilly RJ. 1987. Graft rejection in recipients of T-cell-depleted HLA-nonidentical marrow transplants for leukemia. Transplantation 43: 842-847.
    • (1987) Transplantation , vol.43 , pp. 842-847
    • Kernan, N.A.1    Flomenberg, N.2    Dupont, B.3    O'Reilly, R.J.4
  • 54
    • 0029817245 scopus 로고    scopus 로고
    • Thymic dependence of loss of tolerance in mixed allogeneic bone marrow chimeras after depletion of donor antigen. Peripheral mechanisms do not contribute to maintenance of tolerance
    • Khan A., Tomita Y, Sykes M. 1996. Thymic dependence of loss of tolerance in mixed allogeneic bone marrow chimeras after depletion of donor antigen. Peripheral mechanisms do not contribute to maintenance of tolerance. Transplantation 62: 380-387.
    • (1996) Transplantation , vol.62 , pp. 380-387
    • Khan, A.1    Tomita, Y.2    Sykes, M.3
  • 55
    • 0030987616 scopus 로고    scopus 로고
    • Modifications of the conditioning regimen for achieving mixed chimerism and donor-specific tolerance in cynomolgus monkeys
    • Kimikawa M., Sachs DH, Colvin RB, Bartholomew A, Kawai T, Cosimi AB. 1997. Modifications of the conditioning regimen for achieving mixed chimerism and donor-specific tolerance in cynomolgus monkeys. Transplantation 64: 709-716.
    • (1997) Transplantation , vol.64 , pp. 709-716
    • Kimikawa, M.1    Sachs, D.H.2    Colvin, R.B.3    Bartholomew, A.4    Kawai, T.5    Cosimi, A.B.6
  • 56
    • 70349246939 scopus 로고    scopus 로고
    • TLI and ATGconditioningwith low risk of graftversus-host disease retains antitumor reactions after allogeneic hematopoietic cell transplantation from related and unrelated donors
    • Kohrt H.E., Turnbull BB, Heydari K, Shizuru JA, Laport GG, Miklos D.B., Johnston LJ, Arai S, Weng WK, Hoppe RT, et al. 2009. TLI and ATGconditioningwith low risk of graftversus-host disease retains antitumor reactions after allogeneic hematopoietic cell transplantation from related and unrelated donors. Blood 114: 1099-1109.
    • (2009) Blood , vol.114 , pp. 1099-1109
    • Kohrt, H.E.1    Turnbull, B.B.2    Heydari, K.3    Shizuru, J.A.4    Laport, G.G.5    Miklos, D.B.6    Johnston, L.J.7    Arai, S.8    Weng, W.K.9    Hoppe, R.T.10
  • 58
    • 0037707801 scopus 로고    scopus 로고
    • Early host CD8 T-cell recovery and sensitized anti-donor IL-2-producing and cytolytic T-cell responses associated with marrow graft rejection following nonmyeloablative bone marrow transplantation
    • Kraus A.B., Shaffer J, Toh HC, Preffer F, Dombkowski D, Saidman S., Colby C, George R, Mcafee S, Sackstein R, et al. 2003. Early host CD8 T-cell recovery and sensitized anti-donor IL-2-producing and cytolytic T-cell responses associated with marrow graft rejection following nonmyeloablative bone marrow transplantation. Exp Hematol 31: 609-621.
    • (2003) Exp Hematol , vol.31 , pp. 609-621
    • Kraus, A.B.1    Shaffer, J.2    Toh, H.C.3    Preffer, F.4    Dombkowski, D.5    Saidman, S.6    Colby, C.7    George, R.8    McAfee, S.9    Sackstein, R.10
  • 60
    • 2542450949 scopus 로고    scopus 로고
    • Mechanisms of early peripheral CD4 T cell tolerance induction by anti-CD154 monoclonal antibody and allogeneic bone marrow transplantation: Evidence for anergy and deletion, but not regulatory cells
    • Kurtz J., Shaffer J, Anosova N, Benichou G, Sykes M. 2004. Mechanisms of early peripheral CD4 T cell tolerance induction by anti-CD154 monoclonal antibody and allogeneic bone marrow transplantation: Evidence for anergy and deletion, but not regulatory cells. Blood 103: 4336-4343.
    • (2004) Blood , vol.103 , pp. 4336-4343
    • Kurtz, J.1    Shaffer, J.2    Anosova, N.3    Benichou, G.4    Sykes, M.5
  • 64
    • 84861548052 scopus 로고    scopus 로고
    • Emerging concepts in haematopoietic cell transplantation
    • Li H.W., Sykes M. 2012. Emerging concepts in haematopoietic cell transplantation. Nat Rev Immunol 12: 403-416.
    • (2012) Nat Rev Immunol , vol.12 , pp. 403-416
    • Li, H.W.1    Sykes, M.2
  • 65
    • 84871174421 scopus 로고    scopus 로고
    • Nonalloreactive T cells prevent donor lymphocyte infusion-induced graft-versus-host disease by controlling microbial stimuli
    • Li H.W., Sachs J, Pichardo C, Bronson R, Zhao G, Sykes M. 2012. Nonalloreactive T cells prevent donor lymphocyte infusion-induced graft-versus-host disease by controlling microbial stimuli. J Immunol 189: 5572-5581.
    • (2012) J Immunol , vol.189 , pp. 5572-5581
    • Li, H.W.1    Sachs, J.2    Pichardo, C.3    Bronson, R.4    Zhao, G.5    Sykes, M.6
  • 66
    • 78650807243 scopus 로고    scopus 로고
    • Mixed chimerism, lymphocyte recovery, and evidence for early donor-specific unresponsiveness in patients receiving combined kidney and bone marrow transplantation to induce tolerance
    • Locascio SA, Morokata T, Chittenden M, Preffer FI, Dombkowski DM, Andreola G, Crisalli K, Kawai T, Saidman SL, Spitzer T.R., et al. 2010. Mixed chimerism, lymphocyte recovery, and evidence for early donor-specific unresponsiveness in patients receiving combined kidney and bone marrow transplantation to induce tolerance. Transplantation 90: 1607-1615.
    • (2010) Transplantation , vol.90 , pp. 1607-1615
    • Locascio, S.A.1    Morokata, T.2    Chittenden, M.3    Preffer, F.I.4    Dombkowski, D.M.5    Andreola, G.6    Crisalli, K.7    Kawai, T.8    Saidman, S.L.9    Spitzer, T.R.10
  • 68
    • 79956332711 scopus 로고    scopus 로고
    • LAG-3, TGF-β, and cell-intrinsic PD-1 inhibitory pathways contribute to CD8 but not CD4 Tcell tolerance induced by allogeneic BMT with anti-CD40 L
    • Lucas CL, Workman CJ, Beyaz S, Locascio S, Zhao G, Vignali DA, Sykes M. 2011. LAG-3, TGF-β, and cell-intrinsic PD-1 inhibitory pathways contribute to CD8 but not CD4 Tcell tolerance induced by allogeneic BMT with anti-CD40 L. Blood 117: 5532-5540.
    • (2011) Blood , vol.117 , pp. 5532-5540
    • Lucas, C.L.1    Workman, C.J.2    Beyaz, S.3    Locascio, S.4    Zhao, G.5    Vignali, D.A.6    Sykes, M.7
  • 69
    • 0023589216 scopus 로고
    • Phenotypic and functional characterization of pig lymphocyte populations
    • Lunney J.K., Pescovitz MD. 1987. Phenotypic and functional characterization of pig lymphocyte populations. Vet Immunol Immunopathol 17: 135-144.
    • (1987) Vet Immunol Immunopathol , vol.17 , pp. 135-144
    • Lunney, J.K.1    Pescovitz, M.D.2
  • 70
    • 0037924039 scopus 로고
    • The swine leukocyte antigen (SLA) complex
    • In (ed. Bach F.H., Auchincloss Jr H), Wiley, New York
    • Lunney J.K., Sachs DH. 1995. The swine leukocyte antigen (SLA) complex. In Transplantation immunology (ed. Bach F.H., Auchincloss Jr H), pp. 339-345. Wiley, New York.
    • (1995) Transplantation immunology , pp. 339-345
    • Lunney, J.K.1    Sachs, D.H.2
  • 72
    • 0032528258 scopus 로고    scopus 로고
    • Intrathymic deletion of alloreactive T cells in mixed bone marrow chimeras prepared with a nonmyeloablative conditioning regimen
    • Manilay J.O., Pearson DA, Sergio JJ, Swenson KG, Sykes M. 1998. Intrathymic deletion of alloreactive T cells in mixed bone marrow chimeras prepared with a nonmyeloablative conditioning regimen. Transplantation 66: 96-102.
    • (1998) Transplantation , vol.66 , pp. 96-102
    • Manilay, J.O.1    Pearson, D.A.2    Sergio, J.J.3    Swenson, K.G.4    Sykes, M.5
  • 73
    • 0036720416 scopus 로고    scopus 로고
    • Donor lymphocyte infusions mediate superior graft-versus-leukemia effects in mixed compared to fully allogeneic chimeras: A critical role for host antigen-presenting cells
    • Mapara MY, Kim YM, Wang SP, Bronson R, Sachs DH, Sykes M. 2002. Donor lymphocyte infusions mediate superior graft-versus-leukemia effects in mixed compared to fully allogeneic chimeras: A critical role for host antigen-presenting cells. Blood 100: 1903-1909.
    • (2002) Blood , vol.100 , pp. 1903-1909
    • Mapara, M.Y.1    Kim, Y.M.2    Wang, S.P.3    Bronson, R.4    Sachs, D.H.5    Sykes, M.6
  • 74
    • 0043269255 scopus 로고    scopus 로고
    • DLI-mediated GVL effects in mixed chimeras established with a nonmyeloablative conditioning regimen: Extinction of GVL effects coincides with loss of alloreactive cells following conversion to full donor chimerism
    • MaparaMY, Kim YM, Marx J, Sykes M. 2003. DLI-mediated GVL effects in mixed chimeras established with a nonmyeloablative conditioning regimen: Extinction of GVL effects coincides with loss of alloreactive cells following conversion to full donor chimerism. Transplantation 76: 297-305.
    • (2003) Transplantation , vol.76 , pp. 297-305
    • Mapara, M.Y.1    Kim, Y.M.2    Marx, J.3    Sykes, M.4
  • 77
    • 2342532355 scopus 로고    scopus 로고
    • Regulatory T cells generated by the kidney may mediate the beneficial immune effects of combining kidney with heart transplantation
    • Mezrich J., Yamada K, Sachs DH, Madsen JC. 2004. Regulatory T cells generated by the kidney may mediate the beneficial immune effects of combining kidney with heart transplantation. Surgery 135: 473-478.
    • (2004) Surgery , vol.135 , pp. 473-478
    • Mezrich, J.1    Yamada, K.2    Sachs, D.H.3    Madsen, J.C.4
  • 78
    • 36249010170 scopus 로고    scopus 로고
    • Studies of tolerance and chimerism after combined blood stem cell and kidney transplantation in humans
    • Millan MT. 2005. Studies of tolerance and chimerism after combined blood stem cell and kidney transplantation in humans. Am J Transplant 5(Suppl): 544.
    • (2005) Am J Transplant , vol.5 , Issue.SUPPL. , pp. 544
    • Millan, M.T.1
  • 84
    • 0035069856 scopus 로고    scopus 로고
    • Induction of tolerance by mixed chimerism with nonmyeloblative host conditioning: The importance of overcoming intrathymic alloresistance
    • Nikolic B., Khan A, Sykes M. 2001. Induction of tolerance by mixed chimerism with nonmyeloblative host conditioning: The importance of overcoming intrathymic alloresistance. Biol Blood Marrow Transplant 7: 144-153.
    • (2001) Biol Blood Marrow Transplant , vol.7 , pp. 144-153
    • Nikolic, B.1    Khan, A.2    Sykes, M.3
  • 85
    • 0032617123 scopus 로고    scopus 로고
    • Lymphohematopoietic graft-vs-host reactions can be induced without graft-vs-host disease in murine mixed chimeras established with a cyclophosphamide-based non-myeloablative conditioning regimen
    • Pelot M.R., Pearson DA, Swenson K, Zhao G, Sachs J, Yang YG, Sykes M. 1999. Lymphohematopoietic graft-vs-host reactions can be induced without graft-vs-host disease in murine mixed chimeras established with a cyclophosphamide-based non-myeloablative conditioning regimen. Biol Blood Marrow Transplant 5: 133-143.
    • (1999) Biol Blood Marrow Transplant , vol.5 , pp. 133-143
    • Pelot, M.R.1    Pearson, D.A.2    Swenson, K.3    Zhao, G.4    Sachs, J.5    Yang, Y.G.6    Sykes, M.7
  • 86
    • 0019474536 scopus 로고
    • Transplantation in miniature swine. VIII. Recombination within the major histocompatibility complex of miniature swine
    • Pennington L.R., Lunney JK, Sachs DH. 1981. Transplantation in miniature swine. VIII. Recombination within the major histocompatibility complex of miniature swine. Transplantation 31: 66-71.
    • (1981) Transplantation , vol.31 , pp. 66-71
    • Pennington, L.R.1    Lunney, J.K.2    Sachs, D.H.3
  • 88
    • 0021257507 scopus 로고
    • Localization of class II MHC antigens on porcine renal vascular endothelium
    • Pescovitz M.D., Sachs DH, Lunney JK, Hsu SM. 1984a. Localization of class II MHC antigens on porcine renal vascular endothelium. Transplantation 37: 627-630.
    • (1984) Transplantation , vol.37 , pp. 627-630
    • Pescovitz, M.D.1    Sachs, D.H.2    Lunney, J.K.3    Hsu, S.M.4
  • 90
    • 0025282431 scopus 로고
    • Characterization of a porcine CD1-specific mAb that distinguishes CD4/CD8 double-positive thymic from peripheral T lymphocytes
    • Pescovitz M.D., Hsu SM, Katz SI, Lunney JK, Shimada S, Sachs Dh. 1990. Characterization of a porcine CD1-specific mAb that distinguishes CD4/CD8 double-positive thymic from peripheral T lymphocytes. Tissue Antigens 35: 151-156.
    • (1990) Tissue Antigens , vol.35 , pp. 151-156
    • Pescovitz, M.D.1    Hsu, S.M.2    Katz, S.I.3    Lunney, J.K.4    Shimada, S.5    Sachs, D.6
  • 95
    • 0141455935 scopus 로고    scopus 로고
    • Anti-tumor effect of donor marrow graft rejection induced by recipient leukocyte infusions in mixed chimeras prepared with nonmyeloablative conditioning: Critical role for recipient-derived IFN-γ
    • Rubio M.T., Kim YM, Sachs T, Mapara M, Zhao G, Sykes M. 2003. Anti-tumor effect of donor marrow graft rejection induced by recipient leukocyte infusions in mixed chimeras prepared with nonmyeloablative conditioning: Critical role for recipient-derived IFN-γ. Blood 102: 2300-2307.
    • (2003) Blood , vol.102 , pp. 2300-2307
    • Rubio, M.T.1    Kim, Y.M.2    Sachs, T.3    Mapara, M.4    Zhao, G.5    Sykes, M.6
  • 97
    • 33745235816 scopus 로고    scopus 로고
    • Role of indirect allo-and autoreactivity in anti-tumor responses induced by recipient leukocyte infusions (RLI) in mixed chimeras prepared with nonmyeloablative conditioning
    • Rubio M.T., Zhao G, Buchli J, Chittenden M, Sykes M. 2006. Role of indirect allo-and autoreactivity in anti-tumor responses induced by recipient leukocyte infusions (RLI) in mixed chimeras prepared with nonmyeloablative conditioning. Clin Immunol 120: 33-44.
    • (2006) Clin Immunol , vol.120 , pp. 33-44
    • Rubio, M.T.1    Zhao, G.2    Buchli, J.3    Chittenden, M.4    Sykes, M.5
  • 98
    • 0002800080 scopus 로고
    • MHC homozygous miniature swine
    • In (ed Swindle MM, et al.), Iowa State University Press, Ames, IA
    • Sachs DH. 1992. MHC homozygous miniature swine. In Swine as models in biomedical research (ed Swindle MM, et al.), pp. 3-15. Iowa State University Press, Ames, IA.
    • (1992) Swine as models in biomedical research , pp. 3-15
    • Sachs, D.H.1
  • 99
    • 0028081154 scopus 로고
    • The pig as a potential xenograft donor
    • Sachs DH. 1994. The pig as a potential xenograft donor. Vet Immunol Immunopathol 43: 185-191.
    • (1994) Vet Immunol Immunopathol , vol.43 , pp. 185-191
    • Sachs, D.H.1
  • 100
    • 85047693403 scopus 로고    scopus 로고
    • Tolerance: Of mice and men
    • Sachs DH. 2003. Tolerance: Of mice and men. J Clin Invest 111: 1819-1821.
    • (2003) J Clin Invest , vol.111 , pp. 1819-1821
    • Sachs, D.H.1
  • 101
    • 33747890690 scopus 로고    scopus 로고
    • Clinical relevance of recipient leukocyte infusion as antitumor therapy following nonmyeloablative allogeneic hematopoietic cell transplantation
    • Saito T.I., Rubio MT, Sykes M. 2006. Clinical relevance of recipient leukocyte infusion as antitumor therapy following nonmyeloablative allogeneic hematopoietic cell transplantation. Exp Hematol 34: 1271-1277.
    • (2006) Exp Hematol , vol.34 , pp. 1271-1277
    • Saito, T.I.1    Rubio, M.T.2    Sykes, M.3
  • 104
  • 108
    • 0026556640 scopus 로고
    • Genetic complexity of regulatory mutants defective for HLA class II gene expression
    • Seidl C., Saraiya C, Osterweil Z, Fu YP, Lee JS. 1992. Genetic complexity of regulatory mutants defective for HLA class II gene expression. J Immunol 148: 1576-1584.
    • (1992) J Immunol , vol.148 , pp. 1576-1584
    • Seidl, C.1    Saraiya, C.2    Osterweil, Z.3    Fu, Y.P.4    Lee, J.S.5
  • 109
    • 34250317456 scopus 로고    scopus 로고
    • Regulatory T-cell recovery in recipients of haploidentical nonmyeloablative hematopoietic cell transplantation with a humanized anti-CD2 mAb, MEDI-507, with or without fludarabine
    • Shaffer J., Villard J, Means TK, Alexander S, Dombkowski D, Dey B.R., McAffee S, Ballen KK, Saidman S, Preffer FI, et al. 2007. Regulatory T-cell recovery in recipients of haploidentical nonmyeloablative hematopoietic cell transplantation with a humanized anti-CD2 mAb, MEDI-507, with or without fludarabine. Exp Hematol 35: 1140-1152.
    • (2007) Exp Hematol , vol.35 , pp. 1140-1152
    • Shaffer, J.1    Villard, J.2    Means, T.K.3    Alexander, S.4    Dombkowski, D.5    Dey, B.R.6    McAffee, S.7    Ballen, K.K.8    Saidman, S.9    Preffer, F.I.10
  • 110
    • 0024561069 scopus 로고
    • Mixed chimerism and permanent specific transplantation tolerance induced by a nonlethal preparative regimen
    • Sharabi Y., Sachs DH. 1989. Mixed chimerism and permanent specific transplantation tolerance induced by a nonlethal preparative regimen. J Exp Med 169: 493-502.
    • (1989) J Exp Med , vol.169 , pp. 493-502
    • Sharabi, Y.1    Sachs, D.H.2
  • 112
    • 0017644914 scopus 로고
    • Induction of specific tissue transplantation tolerance using fractionated total lymphoid irradiation in adult mice: Long-term survival of allogeneic bone marrow and skin grafts
    • Slavin S., Strober S, Fuks Z, Kaplan HS. 1977. Induction of specific tissue transplantation tolerance using fractionated total lymphoid irradiation in adult mice: Long-term survival of allogeneic bone marrow and skin grafts. J Exp Med 146: 34.
    • (1977) J Exp Med , vol.146 , pp. 34
    • Slavin, S.1    Strober, S.2    Fuks, Z.3    Kaplan, H.S.4
  • 113
    • 0018406081 scopus 로고
    • Transplantation of bone marrow in outbred dogs without graft-versus-host disease using total lymphoid irradiation
    • Slavin S., Gottlieb M, Strober S, Bieber C, Hoppe R, Kaplan HS, Grumet FC. 1979. Transplantation of bone marrow in outbred dogs without graft-versus-host disease using total lymphoid irradiation. Transplantation 27: 139-142.
    • (1979) Transplantation , vol.27 , pp. 139-142
    • Slavin, S.1    Gottlieb, M.2    Strober, S.3    Bieber, C.4    Hoppe, R.5    Kaplan, H.S.6    Grumet, F.C.7
  • 114
    • 0027371284 scopus 로고
    • Bone marrow transplantation in miniature swine: IV. Development of myeloablative regimens that allow engraftment across major histocompatibility barriers
    • Smith C.V., Suzuki T, Guzzetta PC, Nakajima K, Sundt TM, Mixon A., Spitzer TR, Eckhaus M, Sachs DH. 1993. Bone marrow transplantation in miniature swine: IV. Development of myeloablative regimens that allow engraftment across major histocompatibility barriers. Transplantation 56: 541-549.
    • (1993) Transplantation , vol.56 , pp. 541-549
    • Smith, C.V.1    Suzuki, T.2    Guzzetta, P.C.3    Nakajima, K.4    Sundt, T.M.5    Mixon, A.6    Spitzer, T.R.7    Eckhaus, M.8    Sachs, D.H.9
  • 115
    • 0034988517 scopus 로고    scopus 로고
    • Engraftment syndrome following hematopoietic stem cell transplantation
    • Spitzer TR. 2001. Engraftment syndrome following hematopoietic stem cell transplantation. Bone Marrow Transplant 27: 893-898.
    • (2001) Bone Marrow Transplant , vol.27 , pp. 893-898
    • Spitzer, T.R.1
  • 116
    • 0032852141 scopus 로고    scopus 로고
    • Combined histocompatibility leukocyte antigen-matched donor bone marrow and renal transplantation for multiple myeloma with end stage renal disease: The induction of allograft tolerance through mixed lymphohematopoietic chimerism
    • Spitzer T.R., Delmonico F, Tolkoff-Rubin N, McAfee S, Sackstein R, Saidman S, Colby C, Sykes M, Sachs DH, Cosimi AB. 1999. Combined histocompatibility leukocyte antigen-matched donor bone marrow and renal transplantation for multiple myeloma with end stage renal disease: The induction of allograft tolerance through mixed lymphohematopoietic chimerism. Transplantation 68: 480-484.
    • (1999) Transplantation , vol.68 , pp. 480-484
    • Spitzer, T.R.1    Delmonico, F.2    Tolkoff-Rubin, N.3    McAfee, S.4    Sackstein, R.5    Saidman, S.6    Colby, C.7    Sykes, M.8    Sachs, D.H.9    Cosimi, A.B.10
  • 117
    • 20244388936 scopus 로고    scopus 로고
    • Non-myeloablative haploidentical stem cell transplantation using anti-CD2 monoclonal antibody (MEDI-507)-based conditioning for refractory hematologic malignancies
    • Spitzer T.R., Mcafee S, Dey BR, Colby C, Hope J, Grossberg H, Preffer F, Shaffer J, Alexander SI, Sachs DH, et al. 2003. Non-myeloablative haploidentical stem cell transplantation using anti-CD2 monoclonal antibody (MEDI-507)-based conditioning for refractory hematologic malignancies. Transplantation 75: 1748-1751.
    • (2003) Transplantation , vol.75 , pp. 1748-1751
    • Spitzer, T.R.1    McAfee, S.2    Dey, B.R.3    Colby, C.4    Hope, J.5    Grossberg, H.6    Preffer, F.7    Shaffer, J.8    Alexander, S.I.9    Sachs, D.H.10
  • 118
    • 79952756877 scopus 로고    scopus 로고
    • Long-term follow-up of recipients of combined human leukocyte antigen-matched bone marrow and kidney transplantation for multiple myeloma with endstage renal disease
    • Spitzer T.R., Sykes M, Tolkoff-Rubin N, Kawai T, McAfee SL, Dey B.R., Ballen K, Delmonico F, Saidman S, Sachs DH, et al. 2011. Long-term follow-up of recipients of combined human leukocyte antigen-matched bone marrow and kidney transplantation for multiple myeloma with endstage renal disease. Transplantation 91: 672-676.
    • (2011) Transplantation , vol.91 , pp. 672-676
    • Spitzer, T.R.1    Sykes, M.2    Tolkoff-Rubin, N.3    Kawai, T.4    McAfee, S.L.5    Dey, B.R.6    Ballen, K.7    Delmonico, F.8    Saidman, S.9    Sachs, D.H.10
  • 121
    • 80053472931 scopus 로고    scopus 로고
    • Translational studies in hematopoietic cell transplantation: Treatment of hematologic malignancies as a stepping stone to tolerance induction
    • Strober S., Spitzer TR, Lowsky R, Sykes M. 2011. Translational studies in hematopoietic cell transplantation: Treatment of hematologic malignancies as a stepping stone to tolerance induction. Semin Immunol 23: 273-281.
    • (2011) Semin Immunol , vol.23 , pp. 273-281
    • Strober, S.1    Spitzer, T.R.2    Lowsky, R.3    Sykes, M.4
  • 122
    • 0023724179 scopus 로고
    • Induction of specific transplant tolerance in a large animal model by bone marrow transplantation
    • Sundt TM III, Suzuki T, Kortz O, Eckhaus ME, Gress RE, Sachs DH. 1988. Induction of specific transplant tolerance in a large animal model by bone marrow transplantation. Surgical Forum 39: 365-367.
    • (1988) Surgical Forum , vol.39 , pp. 365-367
    • Sundt III, T.M.1    Suzuki, T.2    Kortz, O.3    Eckhaus, M.E.4    Gress, R.E.5    Sachs, D.H.6
  • 123
    • 0023703061 scopus 로고
    • Mixed allogeneic chimerism as an approach to transplantation tolerance
    • Sykes M., Sachs DH. 1988. Mixed allogeneic chimerism as an approach to transplantation tolerance. Immunol Today 9: 23-27.
    • (1988) Immunol Today , vol.9 , pp. 23-27
    • Sykes, M.1    Sachs, D.H.2
  • 125
    • 0024209925 scopus 로고
    • Graft-versus-hostrelated immunosuppression is induced in mixed chimeras by alloresponses against either host or donor lymphohematopoietic cells
    • Sykes M., Sheard MA, Sachs DH. 1988. Graft-versus-hostrelated immunosuppression is induced in mixed chimeras by alloresponses against either host or donor lymphohematopoietic cells. J Exp Med 168: 2391-2396.
    • (1988) J Exp Med , vol.168 , pp. 2391-2396
    • Sykes, M.1    Sheard, M.A.2    Sachs, D.H.3
  • 127
    • 0028341472 scopus 로고
    • Role of intrathymic clonal deletion and peripheral anergy in transplantation tolerance induced by bone marrow transplantion in mice conditioned with a non-myeloablative regimen
    • Tomita Y., Khan A, Sykes M. 1994. Role of intrathymic clonal deletion and peripheral anergy in transplantation tolerance induced by bone marrow transplantion in mice conditioned with a non-myeloablative regimen. J Immunol 153: 1087-1098.
    • (1994) J Immunol , vol.153 , pp. 1087-1098
    • Tomita, Y.1    Khan, A.2    Sykes, M.3
  • 128
    • 0030050468 scopus 로고    scopus 로고
    • Mechanism by which additional monoclonal antibody injections overcome the requirement for thymic irradiation to achieve mixed chimerism in mice receiving bone marrow transplantation after conditioning with anti-T cell mAbs and 3 Gy whole body irradiation
    • Tomita Y., Khan A, Sykes M. 1996a. Mechanism by which additional monoclonal antibody injections overcome the requirement for thymic irradiation to achieve mixed chimerism in mice receiving bone marrow transplantation after conditioning with anti-T cell mAbs and 3 Gy whole body irradiation. Transplantation 61: 477-485.
    • (1996) Transplantation , vol.61 , pp. 477-485
    • Tomita, Y.1    Khan, A.2    Sykes, M.3
  • 129
    • 0030024697 scopus 로고    scopus 로고
    • Additional mAb injections can replace thymic irradiation to allow induction of mixed chimerism and tolerance in mice receiving bone marrow transplantation after conditioning with anti-T cell mAbs and 3 Gy whole body irradiation
    • Tomita Y., Sachs DH, Khan A, Sykes M. 1996b. Additional mAb injections can replace thymic irradiation to allow induction of mixed chimerism and tolerance in mice receiving bone marrow transplantation after conditioning with anti-T cell mAbs and 3 Gy whole body irradiation. Transplantation 61: 469-477.
    • (1996) Transplantation , vol.61 , pp. 469-477
    • Tomita, Y.1    Sachs, D.H.2    Khan, A.3    Sykes, M.4
  • 130
    • 84891822837 scopus 로고    scopus 로고
    • Induction of tolerance to heart allografts by donor kidney co-transplantation in nonhuman primates (NHPs)
    • Boston
    • Tonsho M. 2012. Induction of tolerance to heart allografts by donor kidney co-transplantation in nonhuman primates (NHPs). American Transplant Congress 2012 Conference Proceedings, Boston, p. 157.
    • (2012) American Transplant Congress 2012 Conference Proceedings , pp. 157
    • Tonsho, M.1
  • 131
    • 0028128077 scopus 로고
    • The role of host T cell subsets in bone marrow rejection directed to isolated major histocompatibility complex class I versus class II differences of bm1 and bm12 mutant mice
    • Vallera D.A., Taylor PA, Sprent J, Blazar BR. 1994. The role of host T cell subsets in bone marrow rejection directed to isolated major histocompatibility complex class I versus class II differences of bm1 and bm12 mutant mice. Transplantation 57: 249-256.
    • (1994) Transplantation , vol.57 , pp. 249-256
    • Vallera, D.A.1    Taylor, P.A.2    Sprent, J.3    Blazar, B.R.4
  • 132
    • 0037091044 scopus 로고    scopus 로고
    • Development of autoimmunity after skin graft rejection via an indirect alloresponse
    • Valujskikh A., Fedoseyeva E, Benichou G, Heeger PS. 2002. Development of autoimmunity after skin graft rejection via an indirect alloresponse. Transplantation 73: 1130-1137.
    • (2002) Transplantation , vol.73 , pp. 1130-1137
    • Valujskikh, A.1    Fedoseyeva, E.2    Benichou, G.3    Heeger, P.S.4
  • 134
    • 0032526283 scopus 로고    scopus 로고
    • Extrathymic T cell deletion and allogeneic stem cell engraftment induced with costimulatory blockade is followed by central T cell tolerance
    • Wekerle T., Sayegh MH, Hill J, Zhao Y, Chandraker A, Swenson KG, Zhao G, Sykes M. 1998. Extrathymic T cell deletion and allogeneic stem cell engraftment induced with costimulatory blockade is followed by central T cell tolerance. J Exp Med 187: 2037-2044.
    • (1998) J Exp Med , vol.187 , pp. 2037-2044
    • Wekerle, T.1    Sayegh, M.H.2    Hill, J.3    Zhao, Y.4    Chandraker, A.5    Swenson, K.G.6    Zhao, G.7    Sykes, M.8
  • 135
    • 0034071426 scopus 로고    scopus 로고
    • Allogeneic bone marrow translantation with costimulatory blockade induces macrochimerism and tolerance without cytoreductive host treatment
    • Wekerle T., Kurtz J, Ito H, Ronquillo JV, Dong V, Zhao G, Shaffer J., Sayegh MH, Sykes M. 2000. Allogeneic bone marrow translantation with costimulatory blockade induces macrochimerism and tolerance without cytoreductive host treatment. Nat Med 6: 464-469.
    • (2000) Nat Med , vol.6 , pp. 464-469
    • Wekerle, T.1    Kurtz, J.2    Ito, H.3    Ronquillo, J.V.4    Dong, V.5    Zhao, G.6    Shaffer, J.7    Sayegh, M.H.8    Sykes, M.9
  • 136
    • 0024077076 scopus 로고
    • Hypothesis: Rheumatoid factors are antiidiotypes related to bacterial or viral Fc receptors
    • Williams RC Jr. 1988. Hypothesis: Rheumatoid factors are antiidiotypes related to bacterial or viral Fc receptors. Arthritis Rheum 31: 1204-1207.
    • (1988) Arthritis Rheum , vol.31 , pp. 1204-1207
    • Williams Jr., R.C.1
  • 139
    • 0018879904 scopus 로고
    • On the immunocompetence of H-2 incompatible irradiation bone marrow chimeras
    • Zinkernagel R.M., Althage A, Callahan G, WelshRMJr. 1980. On the immunocompetence of H-2 incompatible irradiation bone marrow chimeras. J Immunol 124: 2356-2365.
    • (1980) J Immunol , vol.124 , pp. 2356-2365
    • Zinkernagel, R.M.1    Althage, A.2    Callahan, G.3    Welsh Jr., R.M.4


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