Electrochemical reduction of disulfide-containing proteins for hydrogen/deuterium exchange monitored by mass spectrometry

Analytical Chemistry

Volumn 86, Issue 1, 2014, Pages 340-345

  Mysling, Simon ^a   Salbo, Rune ^b   Ploug, Michael ^c   Jørgensen, Thomas J D ^a  

^a UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^b NOVO NORDISK A S   (Denmark)

^c University of Copenhagen   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDE HYDROGENS; AQUEOUS ACIDIC SOLUTION; COLD CONDITIONS; DISULFIDE BONDS; ELECTROCHEMICAL REDUCTIONS; HIGH SALT CONCENTRATION; HYDROGEN/DEUTERIUM EXCHANGE; TRIS(2-CARBOXYETHYL) PHOSPHINE;

COVALENT BONDS; MASS SPECTROMETRY; PHOSPHORUS COMPOUNDS; PROTEINS; RATE CONSTANTS;

ELECTROLYTIC REDUCTION;

DISULFIDE; UROKINASE RECEPTOR;

ARTICLE; CHEMISTRY; DEUTERIUM HYDROGEN EXCHANGE; ELECTROCHEMICAL ANALYSIS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METHODOLOGY; PROTEIN CONFORMATION;

CHROMATOGRAPHY, LIQUID; DEUTERIUM EXCHANGE MEASUREMENT; DISULFIDES; ELECTROCHEMICAL TECHNIQUES; MASS SPECTROMETRY; PROTEIN CONFORMATION; RECEPTORS, UROKINASE PLASMINOGEN ACTIVATOR;

EID: 84891805126     PISSN: 00032700     EISSN: 15206882     Source Type: Journal    
DOI: 10.1021/ac403269a     Document Type: Article

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