-
1
-
-
0000574657
-
Structure of the pig insulin dimer in the cubic crystal
-
Badger, J., Haris, M. R., Reynolds, C. D., Evans, A. C., Dodson, E. J., Dodson, G. G. & North, A. C. T. (1991). Structure of the pig insulin dimer in the cubic crystal. Acta Crystallog. sect. B, 47, 127-136.
-
(1991)
Acta Crystallog. Sect. B
, vol.47
, pp. 127-136
-
-
Badger, J.1
Haris, M.R.2
Reynolds, C.D.3
Evans, A.C.4
Dodson, E.J.5
Dodson, G.G.6
North, A.C.T.7
-
2
-
-
0028964325
-
Neutron diffraction analysis of the solvent accessible volume in cubic insulin crystals
-
Badger, J., Kapulsky, A., Caspar, D. L. & Korszun, R. (1995). Neutron diffraction analysis of the solvent accessible volume in cubic insulin crystals. Nature Struct. Biol. 2, 77-80.
-
(1995)
Nature Struct. Biol.
, vol.2
, pp. 77-80
-
-
Badger, J.1
Kapulsky, A.2
Caspar, D.L.3
Korszun, R.4
-
3
-
-
0024280106
-
The structure of 2Zn pig insulin crystals at 1.5 Å resolution
-
Baker, E. N., Blundell, T. L., Cutfield, J. F., Cutfield, S. M., Dodson, G. G., Hodgkin, D. M. C., Hubbard, R. E., Isaacs, M. W., Reynolds, C. D., Sakabe, K., Sakabe, N. & Vijayan, N. M. (1988). The structure of 2Zn pig insulin crystals at 1.5 Å resolution. Phil. Trans. Roy. Soc. ser. B, 319, 369-456.
-
(1988)
Phil. Trans. Roy. Soc. Ser. B
, vol.319
, pp. 369-456
-
-
Baker, E.N.1
Blundell, T.L.2
Cutfield, J.F.3
Cutfield, S.M.4
Dodson, G.G.5
Hodgkin, D.M.C.6
Hubbard, R.E.7
Isaacs, M.W.8
Reynolds, C.D.9
Sakabe, K.10
Sakabe, N.11
Vijayan, N.M.12
-
4
-
-
5144233105
-
MLEV-17 based two-dimensional homonuclear magnetization transfer spectroscopy
-
Bax, A. & Davis, D. G. (1985). MLEV-17 based two-dimensional homonuclear magnetization transfer spectroscopy. J. Magn. Reson. 65, 355-360.
-
(1985)
J. Magn. Reson.
, vol.65
, pp. 355-360
-
-
Bax, A.1
Davis, D.G.2
-
5
-
-
0017195548
-
Structure of insulin in 4-zinc insulin
-
Bentley, G., Dodson, E. J., Dodson, G. G., Hodgkin, D. C. & Mercola, D. A. (1976). Structure of insulin in 4-zinc insulin. Nature, 261, 166-168.
-
(1976)
Nature
, vol.261
, pp. 166-168
-
-
Bentley, G.1
Dodson, E.J.2
Dodson, G.G.3
Hodgkin, D.C.4
Mercola, D.A.5
-
6
-
-
0028940094
-
Ligand binding to wild-type and EB13Q mutant insulins: A three-state allosteric model system showing half-site reactivity
-
Bloom, C. R., Choi, W. E., Brzovic, P. S., Ha, J. J., Huang, S. T., Kaarsholm, N. C. & Dunn, M. F. (1995). Ligand binding to wild-type and EB13Q mutant insulins: a three-state allosteric model system showing half-site reactivity. J. Mol. Biol. 245, 323-330.
-
(1995)
J. Mol. Biol.
, vol.245
, pp. 323-330
-
-
Bloom, C.R.1
Choi, W.E.2
Brzovic, P.S.3
Ha, J.J.4
Huang, S.T.5
Kaarsholm, N.C.6
Dunn, M.F.7
-
7
-
-
0025339647
-
Two-dimensional NMR studies on despentapeptide-insulin. Proton resonance assignments and secondary structure
-
Boelens, R., Ganadu, M. L., Verheyden, P. & Kaptein, R. (1990). Two-dimensional NMR studies on despentapeptide-insulin. Proton resonance assignments and secondary structure. Eur. J. Biochem. 191, 147-153.
-
(1990)
Eur. J. Biochem.
, vol.191
, pp. 147-153
-
-
Boelens, R.1
Ganadu, M.L.2
Verheyden, P.3
Kaptein, R.4
-
8
-
-
0025827116
-
Insulin hexamers: New conformations, new applications
-
Brader, M. L. & Dunn, M. F. (1991). Insulin hexamers: new conformations, new applications. Trends Biochem. Sci. 16, 341-345.
-
(1991)
Trends Biochem. Sci.
, vol.16
, pp. 341-345
-
-
Brader, M.L.1
Dunn, M.F.2
-
9
-
-
0023936777
-
Monomeric insulins obtained by protein engineering and their medical implications
-
Brange, J., Ribel, U., Hansen, J. F., Dodson, G. G., Hansen, M. T., Havelund, S., Melberg, S. G., Norris, F., Norris, K., Snel, L., Sørensen, A. R. & Voigt, H. O. (1988). Monomeric insulins obtained by protein engineering and their medical implications. Nature, 333, 679-682.
-
(1988)
Nature
, vol.333
, pp. 679-682
-
-
Brange, J.1
Ribel, U.2
Hansen, J.F.3
Dodson, G.G.4
Hansen, M.T.5
Havelund, S.6
Melberg, S.G.7
Norris, F.8
Norris, K.9
Snel, L.10
Sørensen, A.R.11
Voigt, H.O.12
-
10
-
-
0001138158
-
Designing insulin for diabetes therapy by protein engineering
-
Brange, J., Dodson, G. G. & Xiao. B. (1991). Designing insulin for diabetes therapy by protein engineering. Curr. Opin. Struct. Biol. 1, 934-940.
-
(1991)
Curr. Opin. Struct. Biol.
, vol.1
, pp. 934-940
-
-
Brange, J.1
Dodson, G.G.2
Xiao, B.3
-
11
-
-
0026698991
-
Altering the association properties of insulin by amino acid replacement
-
Brems, D. N., Alter, L. A., Beckage, M. J., Chance, R. E., DiMarchi, R. D., Green, L. K., Long, H. B., Pekar, A. H., Shields, J. E. & Frank, B. H. (1992). Altering the association properties of insulin by amino acid replacement. Protein Eng. 5, 527-533.
-
(1992)
Protein Eng.
, vol.5
, pp. 527-533
-
-
Brems, D.N.1
Alter, L.A.2
Beckage, M.J.3
Chance, R.E.4
DiMarchi, R.D.5
Green, L.K.6
Long, H.B.7
Pekar, A.H.8
Shields, J.E.9
Frank, B.H.10
-
13
-
-
0028150624
-
Structural asymmetry and half-site reactivity in the T to R allosteric transition of the insulin hexamer
-
Brzovic, P. S., Choi, W. E., Borchardt, D., Kaarsholm, N. C. & Dunn, M. F. (1994). Structural asymmetry and half-site reactivity in the T to R allosteric transition of the insulin hexamer. Biochemistry, 33, 13057-13069.
-
(1994)
Biochemistry
, vol.33
, pp. 13057-13069
-
-
Brzovic, P.S.1
Choi, W.E.2
Borchardt, D.3
Kaarsholm, N.C.4
Dunn, M.F.5
-
14
-
-
84985733652
-
1H-NMR parameters of the common amino acid residues measured in aqueous solution of the linear tetrapeptides H-Gly-Gly-X-L-Ala-OH
-
1H-NMR parameters of the common amino acid residues measured in aqueous solution of the linear tetrapeptides H-Gly-Gly-X-L-Ala-OH. Biopolymers, 18, 285-298.
-
(1979)
Biopolymers
, vol.18
, pp. 285-298
-
-
Bundi, A.1
Wüthrich, K.2
-
15
-
-
0028672867
-
Use of chemical shifts and coupling constants in nuclear magnetic resonance structural studies on peptides and proteins
-
Case, D. A., Dyson, H. J. & Wright, P. E. (1994). Use of chemical shifts and coupling constants in nuclear magnetic resonance structural studies on peptides and proteins. Methods Enzymol. 239, 392-416.
-
(1994)
Methods Enzymol.
, vol.239
, pp. 392-416
-
-
Case, D.A.1
Dyson, H.J.2
Wright, P.E.3
-
16
-
-
0002365618
-
Insulin, a molecular dynamics analysis
-
(Goodfellow, J. M., ed.), MacMillan Press, London, UK
-
Caves, L. S. D., Nguyen, D. T. & Hubbard, R. E. (1990). Insulin, a molecular dynamics analysis. In Molecular Dynamics: Application in Molecular Biology (Goodfellow, J. M., ed.), pp 27-68, MacMillan Press, London, UK.
-
(1990)
Molecular Dynamics: Application in Molecular Biology
, pp. 27-68
-
-
Caves, L.S.D.1
Nguyen, D.T.2
Hubbard, R.E.3
-
17
-
-
0020614069
-
Transmission of conformational change in insulin
-
Chothia, C., Lesk, A. M., Dodson, G. G. & Hodgkin, D. C. (1983). Transmission of conformational change in insulin. Nature, 302, 500-505.
-
(1983)
Nature
, vol.302
, pp. 500-505
-
-
Chothia, C.1
Lesk, A.M.2
Dodson, G.G.3
Hodgkin, D.C.4
-
18
-
-
0029644942
-
B29-human insulin
-
B29-human insulin. Structure, 3, 615-622.
-
(1995)
Structure
, vol.3
, pp. 615-622
-
-
Ciszak, E.1
Beals, J.M.2
Frank, B.H.3
Baker, J.C.4
Carter, N.C.5
Smith, G.D.6
-
19
-
-
0002608849
-
Applications of three- And four-dimensional heteronuclear NMR spectroscopy to protein structure determination
-
Clore, G. M. & Gronenborn, A. M. (1991). Applications of three- and four-dimensional heteronuclear NMR spectroscopy to protein structure determination. Prog. Nucl. Magn. Reson. Spectrosc. 23, 43-92.
-
(1991)
Prog. Nucl. Magn. Reson. Spectrosc.
, vol.23
, pp. 43-92
-
-
Clore, G.M.1
Gronenborn, A.M.2
-
20
-
-
0028124665
-
High-resolution structure of the oligomerization domain of p53 by multidimensional NMR
-
Clore, G. M., Omichinski, J. G., Sakaguchi, K., Zambrano, N., Sakamoto, H., Appella, E. & Gronenborn, A. M. (1994). High-resolution structure of the oligomerization domain of p53 by multidimensional NMR. Science, 265, 386-391.
-
(1994)
Science
, vol.265
, pp. 386-391
-
-
Clore, G.M.1
Omichinski, J.G.2
Sakaguchi, K.3
Zambrano, N.4
Sakamoto, H.5
Appella, E.6
Gronenborn, A.M.7
-
21
-
-
0028965832
-
Refined solution structure of the oligomerization domain of p53
-
Clore, G. M., Ernst, J., Clubb, R., Omichinski, J. G., Kennedy, W. M. P., Sakaguchi, K., Sakamoto, H., Appella, E. & Gronenborn, A. M. (1995). Refined solution structure of the oligomerization domain of p53. Nature Struct. Biol. 2, 321-333.
-
(1995)
Nature Struct. Biol.
, vol.2
, pp. 321-333
-
-
Clore, G.M.1
Ernst, J.2
Clubb, R.3
Omichinski, J.G.4
Kennedy, W.M.P.5
Sakaguchi, K.6
Sakamoto, H.7
Appella, E.8
Gronenborn, A.M.9
-
22
-
-
0027308278
-
Secondary and tertiary structural effects on protein NMR chemical shifts: An ab-initio approach
-
DeDios, A. C., Pearson, J. G. & Oldfield, E. (1993). Secondary and tertiary structural effects on protein NMR chemical shifts: an ab-initio approach. Science, 260, 1491-1496.
-
(1993)
Science
, vol.260
, pp. 1491-1496
-
-
DeDios, A.C.1
Pearson, J.G.2
Oldfield, E.3
-
23
-
-
0347590024
-
Phenol stabilizes more helix in a new symmetrical zinc insulin hexamer
-
Derewenda, U., Derewenda, Z., Dodson, E. J., Dodson, G. G., Reynolds, C., Smith, G. D., Sparks, C. & Swenson, D. (1989). Phenol stabilizes more helix in a new symmetrical zinc insulin hexamer. Nature, 261, 166-168.
-
(1989)
Nature
, vol.261
, pp. 166-168
-
-
Derewenda, U.1
Derewenda, Z.2
Dodson, E.J.3
Dodson, G.G.4
Reynolds, C.5
Smith, G.D.6
Sparks, C.7
Swenson, D.8
-
24
-
-
0006548377
-
Insulin structure
-
(Cuatrecasa, P & Jacobs, S., eds), Springer-Verlag, Berlin, Germany
-
Derewenda, U., Derewenda, Z., Dodson, G. G. & Hubbard, R. E. (1990). Insulin structure. In Insulin, Handbook of Experimental Pharmacology (Cuatrecasa, P & Jacobs, S., eds), vol. 92, p. 23-39, Springer-Verlag, Berlin, Germany
-
(1990)
Insulin, Handbook of Experimental Pharmacology
, vol.92
, pp. 23-39
-
-
Derewenda, U.1
Derewenda, Z.2
Dodson, G.G.3
Hubbard, R.E.4
-
25
-
-
0025880180
-
X-ray analysis of the single-chain B29-A1 peptide linked insulin molecule
-
Derewenda, U., Derewenda, Z., Dodson, E. J., Dodson, G. G., Bing, X. G. & Markussen, J. (1991). X-ray analysis of the single-chain B29-A1 peptide linked insulin molecule. J. Mol. Biol. 220, 425-433.
-
(1991)
J. Mol. Biol.
, vol.220
, pp. 425-433
-
-
Derewenda, U.1
Derewenda, Z.2
Dodson, E.J.3
Dodson, G.G.4
Bing, X.G.5
Markussen, J.6
-
26
-
-
0002002069
-
Synthesis of a fast acting insulin based on structural homology with insulin-like growth factor 1
-
(Smith, J. A. & Rivier, J. W., eds), ESCOM, Leiden, Netherlands
-
DiMarchi, R. D., Mayer, J. P., Fan, L., Brems, D. N., Frank, B. H., Green, L. K., Hoffman, J. A., Howey, D. C., Long, H. B., Shaw, W. N., Shields, J. E., Slieker, L. J., Su, K. S. E., Sundell, K. L. & Chance, R. E. (1992). Synthesis of a fast acting insulin based on structural homology with insulin-like growth factor 1. In Peptides: Chemistry and Biology, Proceedings of the Twelfth American Peptide Symposium (Smith, J. A. & Rivier, J. W., eds), pp. 26-28, ESCOM, Leiden, Netherlands.
-
(1992)
Peptides: Chemistry and Biology, Proceedings of the Twelfth American Peptide Symposium
, pp. 26-28
-
-
DiMarchi, R.D.1
Mayer, J.P.2
Fan, L.3
Brems, D.N.4
Frank, B.H.5
Green, L.K.6
Hoffman, J.A.7
Howey, D.C.8
Long, H.B.9
Shaw, W.N.10
Shields, J.E.11
Slieker, L.J.12
Su, K.S.E.13
Sundell, K.L.14
Chance, R.E.15
-
27
-
-
0018176030
-
Zinc-free cubic pig insulin: Crystallization and structure determination
-
Dodson, E. J., Dodson, G. G., Lewitova, A. & Sabesan, M. (1978). Zinc-free cubic pig insulin: crystallization and structure determination. J. Mol. Biol. 125, 387-396.
-
(1978)
J. Mol. Biol.
, vol.125
, pp. 387-396
-
-
Dodson, E.J.1
Dodson, G.G.2
Lewitova, A.3
Sabesan, M.4
-
28
-
-
0026614434
-
The T-R structural transition of insulin; pathways suggested by targeted energy minimization
-
Engels, M., Jacoby, E., Krüger, P., Schlitter, J. & Wollmer, A. (1992). The T-R structural transition of insulin; pathways suggested by targeted energy minimization. Protein Eng. 5, 669-677.
-
(1992)
Protein Eng.
, vol.5
, pp. 669-677
-
-
Engels, M.1
Jacoby, E.2
Krüger, P.3
Schlitter, J.4
Wollmer, A.5
-
29
-
-
0000502584
-
Sur les constantes π dans les heterocycles conjugues d'interet biologique
-
Giessner-Prettre, C. & Pullman, B. (1969). Sur les constantes π dans les heterocycles conjugues d'interet biologique. C. R. Acad. Sci. Ser. D, 268, 1115-1117.
-
(1969)
C. R. Acad. Sci. Ser. D
, vol.268
, pp. 1115-1117
-
-
Giessner-Prettre, C.1
Pullman, B.2
-
30
-
-
0028024360
-
Amide hydrogen exchange of the central B-chain helix within the T and R-states of insulin hexamers
-
Hardaway, L. A., Brems, D. N., Beals, J. M. & Mackenzie, N. E. (1994). Amide hydrogen exchange of the central B-chain helix within the T and R-states of insulin hexamers. Biochim. Biophys. Acta, 1208, 101-103.
-
(1994)
Biochim. Biophys. Acta
, vol.1208
, pp. 101-103
-
-
Hardaway, L.A.1
Brems, D.N.2
Beals, J.M.3
Mackenzie, N.E.4
-
31
-
-
0025932859
-
An evaluation of computational strategies for use in the determination of protein structure from distance constraints obtained by nuclear magnetic resonance
-
Havel, T. F. (1991). An evaluation of computational strategies for use in the determination of protein structure from distance constraints obtained by nuclear magnetic resonance. Prog. Biophys. Mol. Biol. 56, 43-78.
-
(1991)
Prog. Biophys. Mol. Biol.
, vol.56
, pp. 43-78
-
-
Havel, T.F.1
-
32
-
-
0020484770
-
Flucuations and averaging of proton chemical shifts in the bovine pancreatic trypsin inhibitor
-
Hoch, J. C., Dobson, C. M. & Karplus, M. (1982). Flucuations and averaging of proton chemical shifts in the bovine pancreatic trypsin inhibitor. Biochemistry, 21, 1118-1125.
-
(1982)
Biochemistry
, vol.21
, pp. 1118-1125
-
-
Hoch, J.C.1
Dobson, C.M.2
Karplus, M.3
-
33
-
-
0027753965
-
Contribution of B16 and B26 tyrosine residues to the biological activity of insulin
-
Hu, S. Q., Bruke, T. & Katsoyannis, P. G. (1993). Contribution of B16 and B26 tyrosine residues to the biological activity of insulin. J. Protein Chem. 12, 741-747.
-
(1993)
J. Protein Chem.
, vol.12
, pp. 741-747
-
-
Hu, S.Q.1
Bruke, T.2
Katsoyannis, P.G.3
-
34
-
-
0025251933
-
1H-NMR assignment of des-pentapeptide analogue and comparison with crystal structure
-
1H-NMR assignment of des-pentapeptide analogue and comparison with crystal structure. Biochemisty, 29, 10545-10555.
-
(1990)
Biochemisty
, vol.29
, pp. 10545-10555
-
-
Hua, Q.X.1
Weiss, M.A.2
-
35
-
-
0025778802
-
Comparative 2D NMR studies of human insulin and des pentapeptide insulin: Sequential resonance assignment and implications for protein dynamics and receptor recognition
-
Hua, Q. X. & Weiss, M. A. (1991). Comparative 2D NMR studies of human insulin and des pentapeptide insulin: sequential resonance assignment and implications for protein dynamics and receptor recognition. Biochemistry, 30, 5505-5515.
-
(1991)
Biochemistry
, vol.30
, pp. 5505-5515
-
-
Hua, Q.X.1
Weiss, M.A.2
-
36
-
-
0025996911
-
Receptor binding redefined by a structural switch in a mutant insulin
-
Hua, Q. X., Shoelson, S. E., Kochoyan, M. & Weiss, M. A. (1991). Receptor binding redefined by a structural switch in a mutant insulin. Nature, 354, 238-241.
-
(1991)
Nature
, vol.354
, pp. 238-241
-
-
Hua, Q.X.1
Shoelson, S.E.2
Kochoyan, M.3
Weiss, M.A.4
-
37
-
-
0026482979
-
13C-NMR isotope aided 2D NMR studies of [Phe B24-Gly]insulin with implications for receptor recognition
-
13C-NMR isotope aided 2D NMR studies of [Phe B24-Gly]insulin with implications for receptor recognition. Biochemistry, 31, 11940-11951.
-
(1992)
Biochemistry
, vol.31
, pp. 11940-11951
-
-
Hua, Q.X.1
Shoelson, S.E.2
Weiss, M.A.3
-
38
-
-
0027458937
-
Paradoxical structure and function in a mutant human insulin associated with diabetes mellitus
-
Hua, Q. X., Shoelson, S. E., Inouye, K. & Weiss, M. A. (1993a). Paradoxical structure and function in a mutant human insulin associated with diabetes mellitus. Proc. Natl Acad. Sci. USA, 90, 582-586.
-
(1993)
Proc. Natl Acad. Sci. USA
, vol.90
, pp. 582-586
-
-
Hua, Q.X.1
Shoelson, S.E.2
Inouye, K.3
Weiss, M.A.4
-
39
-
-
0026549524
-
Structure and dynamics of des-pentapeptide insulin in solution: The molten globule hypothesis
-
Hua, Q. X., Kochoyan, M. & Weiss, M. A. (1993b). Structure and dynamics of des-pentapeptide insulin in solution: the molten globule hypothesis. Proc. Natl Acad. Sci. USA, 89, 2379-2383.
-
(1993)
Proc. Natl Acad. Sci. USA
, vol.89
, pp. 2379-2383
-
-
Hua, Q.X.1
Kochoyan, M.2
Weiss, M.A.3
-
40
-
-
0027407097
-
Dynamics of a monomeric insulin analogue: Testing the molten-globule hypothesis
-
Hua, Q. X., Ladbury, J. E. & Weiss, M. A. (1993c). Dynamics of a monomeric insulin analogue: testing the molten-globule hypothesis. Biochemistry, 32, 1433-1442.
-
(1993)
Biochemistry
, vol.32
, pp. 1433-1442
-
-
Hua, Q.X.1
Ladbury, J.E.2
Weiss, M.A.3
-
41
-
-
0027162763
-
Comparison of the dynamics of an engineered insulin monomer and dimer by acid-quenched amide proton exchange. Non-local stabilization of the interchain hydrogen bonds by dimerization
-
Hua, Q. X., Jia, W., Frank, B. H. & Weiss, M. A. (1993d). Comparison of the dynamics of an engineered insulin monomer and dimer by acid-quenched amide proton exchange. Non-local stabilization of the interchain hydrogen bonds by dimerization. J. Mol. Biol. 230, 387-394.
-
(1993)
J. Mol. Biol.
, vol.230
, pp. 387-394
-
-
Hua, Q.X.1
Jia, W.2
Frank, B.H.3
Weiss, M.A.4
-
42
-
-
0029566026
-
Structure of a protein in a kinetic trap
-
Hua, Q. X., Gozani, S. N., Chance, R. E., Hoffmann, J. A., Frank, B. H. & Weiss, M. A. (1995). Structure of a protein in a kinetic trap. Nature Struct. Biol. 2, 129-138.
-
(1995)
Nature Struct. Biol.
, vol.2
, pp. 129-138
-
-
Hua, Q.X.1
Gozani, S.N.2
Chance, R.E.3
Hoffmann, J.A.4
Frank, B.H.5
Weiss, M.A.6
-
43
-
-
0024427465
-
NMR studies of the Escherichia coli trp aporepressor sequence specific assignment of the aromatic proton resonances
-
Hyde, E. I., Ramesh, V., Roberts, G. C., Arrowsmith, C. H., Treat-Clemons, L., Klaic, B. & Jardetzky, O. (1989). NMR studies of the Escherichia coli trp aporepressor sequence specific assignment of the aromatic proton resonances. Eur. J. Biochem. 183, 545-553.
-
(1989)
Eur. J. Biochem.
, vol.183
, pp. 545-553
-
-
Hyde, E.I.1
Ramesh, V.2
Roberts, G.C.3
Arrowsmith, C.H.4
Treat-Clemons, L.5
Klaic, B.6
Jardetzky, O.7
-
44
-
-
0027654704
-
Distinction of structural reorganization and ligand binding in the T-R transition of insulin on the basis of allosteric models
-
Jacoby, E., Krüger, P., Karatas, Y. & Wollmer, A. (1993). Distinction of structural reorganization and ligand binding in the T-R transition of insulin on the basis of allosteric models. Biol. Chem. Hoppe-Seyler, 374, 877-385.
-
(1993)
Biol. Chem. Hoppe-Seyler
, vol.374
, pp. 877-1385
-
-
Jacoby, E.1
Krüger, P.2
Karatas, Y.3
Wollmer, A.4
-
45
-
-
10944271376
-
Calculation of nuclear magnetic resonance spectra of aromatic hydrocarbons
-
Johnson, C. E. & Bovey, F. A. (1958). Calculation of nuclear magnetic resonance spectra of aromatic hydrocarbons. J. Chem. Phys. 29, 1012-1017.
-
(1958)
J. Chem. Phys.
, vol.29
, pp. 1012-1017
-
-
Johnson, C.E.1
Bovey, F.A.2
-
46
-
-
0026492003
-
Three-dimensional solution structure of an insulin dimer. a study of the B9(Asp) mutant of a human insulin using nuclear magnetic resonance, distance geometry and restrained molecular dynamics
-
Jørgensen, A. M. M., Kristensen, S. M., Led, J. J. & Balschmidt, P. (1992). Three-dimensional solution structure of an insulin dimer. A study of the B9(Asp) mutant of a human insulin using nuclear magnetic resonance, distance geometry and restrained molecular dynamics. J. Mol. Biol. 227, 1146-1163.
-
(1992)
J. Mol. Biol.
, vol.227
, pp. 1146-1163
-
-
Jørgensen, A.M.M.1
Kristensen, S.M.2
Led, J.J.3
Balschmidt, P.4
-
47
-
-
0024356816
-
Comparison of solution structural flexibility and zinc binding domains for insulin, proinsulin, and miniproinsulin
-
Kaarsholm, N. C., Ko, H. C. & Dunn, M. F. (1989). Comparison of solution structural flexibility and zinc binding domains for insulin, proinsulin, and miniproinsulin. Biochemistry, 28, 4427-4435.
-
(1989)
Biochemistry
, vol.28
, pp. 4427-4435
-
-
Kaarsholm, N.C.1
Ko, H.C.2
Dunn, M.F.3
-
50
-
-
0026046936
-
1H-NMR study of des-(B26-B30)-insulin in combination with distance geometry and restrained molecular dynamics
-
1H-NMR study of des-(B26-B30)-insulin in combination with distance geometry and restrained molecular dynamics. Eur. J. Biochem. 202, 447-458.
-
(1991)
Eur. J. Biochem.
, vol.202
, pp. 447-458
-
-
Knetgel, R.M.A.1
Boelens, R.2
Ganadu, M.L.3
Kaptein, R.4
-
51
-
-
84994912262
-
A carbon-13 NMR study of the Asp(B9) mutant of human insulin: Sequence specific carbon-13 assignments and structural information
-
Kristensen, S. M. & Led, J. J. (1995). A carbon-13 NMR study of the Asp(B9) mutant of human insulin: sequence specific carbon-13 assignments and structural information. Magn. Reson. Chem. 33, 461-470.
-
(1995)
Magn. Reson. Chem.
, vol.33
, pp. 461-470
-
-
Kristensen, S.M.1
Led, J.J.2
-
52
-
-
0026070498
-
Proton nuclear magnetic resonance study of the B9(Asp) mutant of human insulin. Sequential assignment and secondary structure
-
Kristensen, S. M., Jørgensen, A. M. M., Led, J. J., Balschmidt, P. & Hansen, F. B. (1991). Proton nuclear magnetic resonance study of the B9(Asp) mutant of human insulin. Sequential assignment and secondary structure. J. Mol. Biol. 218, 221-231.
-
(1991)
J. Mol. Biol.
, vol.218
, pp. 221-231
-
-
Kristensen, S.M.1
Jørgensen, A.M.M.2
Led, J.J.3
Balschmidt, P.4
Hansen, F.B.5
-
53
-
-
0023573161
-
The simulated dynamics of insulin monosomers and their relation to the molecule's structure
-
Krüger, P., Straßburger, W., Wollmer, A, van Gunsteren, W. F. & Dobson, G. G. (1987). The simulated dynamics of insulin monosomers and their relation to the molecule's structure. Eur. Biophys. J. 14, 449-459.
-
(1987)
Eur. Biophys. J.
, vol.14
, pp. 449-459
-
-
Krüger, P.1
Straßburger, W.2
Wollmer, A.3
Van Gunsteren, W.F.4
Dobson, G.G.5
-
54
-
-
0019327003
-
A two-dimensional nuclear Overhauser enhancement 2D-NOE experiment for the elucidation of complete proton-proton cross-relaxation networks in biological macromolecules
-
Kumar, A., Ernst, R. R. & Wüthrich, K. (1980). A two-dimensional nuclear Overhauser enhancement 2D-NOE experiment for the elucidation of complete proton-proton cross-relaxation networks in biological macromolecules. Biochem. Biophys. Res. Commun. 95, 1-6.
-
(1980)
Biochem. Biophys. Res. Commun.
, vol.95
, pp. 1-6
-
-
Kumar, A.1
Ernst, R.R.2
Wüthrich, K.3
-
55
-
-
84970061891
-
Solution structure of the tetrameric minimum transforming domain of p53
-
Lee, W., Harvey, T. S., Yin, Y., Yau, P., Litchfield, D. & Arrowsmith, C. H. (1994). Solution structure of the tetrameric minimum transforming domain of p53. Nature Struct. Biol. 1, 877-888.
-
(1994)
Nature Struct. Biol.
, vol.1
, pp. 877-888
-
-
Lee, W.1
Harvey, T.S.2
Yin, Y.3
Yau, P.4
Litchfield, D.5
Arrowsmith, C.H.6
-
56
-
-
0029079250
-
Solution and rotational dynamics of fluorescently labeled insulin in aqueous solution and at the amphiphile-water interface of reversed micelles
-
Lenz, V. J., Federwisch, M., Gattner, H.-G., Brandenburg, D., Höcker, H., Hassiepen, U. & Wollmer, A. (1995). Solution and rotational dynamics of fluorescently labeled insulin in aqueous solution and at the amphiphile-water interface of reversed micelles. Biochemistry, 34, 6130-6141.
-
(1995)
Biochemistry
, vol.34
, pp. 6130-6141
-
-
Lenz, V.J.1
Federwisch, M.2
Gattner, H.-G.3
Brandenburg, D.4
Höcker, H.5
Hassiepen, U.6
Wollmer, A.7
-
57
-
-
0028936409
-
NMR structure determination of tick anticoagulant peptide (TAP)
-
Lim-Wilby, M. S. L., Hallenga, K., De Mayer, M., Lasters, I., Vlasuk, G. P. & Brunck, T. K. (1995). NMR structure determination of tick anticoagulant peptide (TAP). Protein Sci. 4, 178-186.
-
(1995)
Protein Sci.
, vol.4
, pp. 178-186
-
-
Lim-Wilby, M.S.L.1
Hallenga, K.2
De Mayer, M.3
Lasters, I.4
Vlasuk, G.P.5
Brunck, T.K.6
-
58
-
-
0028241787
-
High-resolution structure of an engineered biologically potent insulin monomer, B16 Tyr → His, as determined by nuclear magnetic resonance spectroscopy
-
Ludvigsen, S., Roy, M., Tørgersen, H. & Kaarsholm, N. C. (1994). High-resolution structure of an engineered biologically potent insulin monomer, B16 Tyr → His, as determined by nuclear magnetic resonance spectroscopy Biochemistry, 33, 7998-8006.
-
(1994)
Biochemistry
, vol.33
, pp. 7998-8006
-
-
Ludvigsen, S.1
Roy, M.2
Tørgersen, H.3
Kaarsholm, N.C.4
-
59
-
-
0026343488
-
Conformational flexibility of aqueous and dimeric insulin - A molecular dynmics study
-
Mark, A. E., Berendsen, J. C. & van Gunsteren, W. F. (1991). Conformational flexibility of aqueous and dimeric insulin - a molecular dynmics study. Biochemistry, 30, 10866-10872.
-
(1991)
Biochemistry
, vol.30
, pp. 10866-10872
-
-
Mark, A.E.1
Berendsen, J.C.2
Van Gunsteren, W.F.3
-
60
-
-
0021858162
-
Single chain des-(B30)-insulin. Intramolecular crosslinking of insulin by trypsin catalyzed transpeptidation
-
Markussen, J., Jørgensen, K. H., Sørensen, A. R. & Thim, L. (1985). Single chain des-(B30)-insulin. Intramolecular crosslinking of insulin by trypsin catalyzed transpeptidation. Int. J. Pept. Prot. Res. 26, 70-77.
-
(1985)
Int. J. Pept. Prot. Res.
, vol.26
, pp. 70-77
-
-
Markussen, J.1
Jørgensen, K.H.2
Sørensen, A.R.3
Thim, L.4
-
61
-
-
0025978173
-
Importance of the character and configuration of residues B24, B25 and B26 in insulin-receptor interactions
-
Mirmira, R. G., Nakagawa, S. H. & Tager, H. S. (1991). Importance of the character and configuration of residues B24, B25 and B26 in insulin-receptor interactions. J. Biol. Chem. 266, 1428-1436.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 1428-1436
-
-
Mirmira, R.G.1
Nakagawa, S.H.2
Tager, H.S.3
-
62
-
-
0022879089
-
Role of the phenylalanine B25 side-chain in directing insulin interaction with its receptor
-
Nakagawa, S. H. & Tager, H. S. (1986). Role of the phenylalanine B25 side-chain in directing insulin interaction with its receptor. J. Biol. Chem. 261, 7332-7341.
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 7332-7341
-
-
Nakagawa, S.H.1
Tager, H.S.2
-
63
-
-
0346958887
-
Importance of main-chain flexibility and the insulin fold in insulin-receptor interactions
-
Nakagawa, S. H. & Tager, H. S. (1993). Importance of main-chain flexibility and the insulin fold in insulin-receptor interactions. Biochemistry, 31, 3204-3214.
-
(1993)
Biochemistry
, vol.31
, pp. 3204-3214
-
-
Nakagawa, S.H.1
Tager, H.S.2
-
65
-
-
0025894164
-
Relaxation matrix refinement of the solution structure of squash trypsin inhibitor
-
Nilges, M., Habszettl, J., Brünger, A. T. & Holak, T. A. (1991). Relaxation matrix refinement of the solution structure of squash trypsin inhibitor. J. Mol. Biol. 219, 499-510.
-
(1991)
J. Mol. Biol.
, vol.219
, pp. 499-510
-
-
Nilges, M.1
Habszettl, J.2
Brünger, A.T.3
Holak, T.A.4
-
66
-
-
0000866952
-
Practical and theoretical aspects of three dimensional homonuclear Hartman-Hahn nuclear Overhauser enhancement spectroscopy of proteins
-
Oschkinat, H., Cieslar, C., Holak, T. A., Clore, G. M. & Gronenborn, A. M. (1989). Practical and theoretical aspects of three dimensional homonuclear Hartman-Hahn nuclear Overhauser enhancement spectroscopy of proteins. J. Magn. Reson. 83, 450-472.
-
(1989)
J. Magn. Reson.
, vol.83
, pp. 450-472
-
-
Oschkinat, H.1
Cieslar, C.2
Holak, T.A.3
Clore, G.M.4
Gronenborn, A.M.5
-
67
-
-
0024276810
-
2+ to the Glu(B13) sites drives hexamer assembly and induces a conformation change
-
2+ to the Glu(B13) sites drives hexamer assembly and induces a conformation change. Biochemistry, 27, 3387-3397.
-
(1988)
Biochemistry
, vol.27
, pp. 3387-3397
-
-
Palimeri, R.1
Lee, R.W.K.2
Dunn, M.F.3
-
68
-
-
0015522139
-
Conformation of proinsulin. a comparison of insulin and proinsulin self-association at neutral pH
-
Pekar, A. H. & Frank, B. H. (1972). Conformation of proinsulin. A comparison of insulin and proinsulin self-association at neutral pH. Biochemistry, 11, 4013-4019.
-
(1972)
Biochemistry
, vol.11
, pp. 4013-4019
-
-
Pekar, A.H.1
Frank, B.H.2
-
69
-
-
0005963761
-
Multiple quantum filters for elucidating NMR coupling networks
-
Piantini, U., Sørensen, O. W. & Ernst, R. R. (1982). Multiple quantum filters for elucidating NMR coupling networks. J. Am. Chem. Soc. 104, 6800-6801.
-
(1982)
J. Am. Chem. Soc.
, vol.104
, pp. 6800-6801
-
-
Piantini, U.1
Sørensen, O.W.2
Ernst, R.R.3
-
70
-
-
0021186636
-
A solution equivalent of the 2Zn → 4 Zn transformation of insulin in the crystal
-
Renscheidt, H., Straßburger, W., Glatter, U., Wollmer, A., Dodson, G. G. & Mercola, D. A. (1984). A solution equivalent of the 2Zn → 4 Zn transformation of insulin in the crystal. Eur. J. Biochem. 142, 7-14.
-
(1984)
Eur. J. Biochem.
, vol.142
, pp. 7-14
-
-
Renscheidt, H.1
Straßburger, W.2
Glatter, U.3
Wollmer, A.4
Dodson, G.G.5
Mercola, D.A.6
-
71
-
-
0024807512
-
Spectroscopic signatures of the T to R conformational transition in the insulin hexamer
-
Roy, M., Brader, M. L., Lee, R. W. K., Kaarsholm, N. C., Hansen, J. F. H. & Dunn, M. F. (1989). Spectroscopic signatures of the T to R conformational transition in the insulin hexamer. J. Biol. Chem. 264(32), 19,081-19,085.
-
(1989)
J. Biol. Chem.
, vol.264
, Issue.32
, pp. 19081-19085
-
-
Roy, M.1
Brader, M.L.2
Lee, R.W.K.3
Kaarsholm, N.C.4
Hansen, J.F.H.5
Dunn, M.F.6
-
72
-
-
0025706021
-
1H-NMR assignments for the aromatic regions of several biological active monomeric insulins including native insulin
-
1H-NMR assignments for the aromatic regions of several biological active monomeric insulins including native insulin. Biochim. Biophys. Acta, 1053, 63-73.
-
(1990)
Biochim. Biophys. Acta
, vol.1053
, pp. 63-73
-
-
Roy, M.1
Lee, R.W.K.2
Kaarsholm, N.C.3
Thorgersen, H.4
Brange, J.5
Dunn, M.F.6
-
73
-
-
0027794972
-
Targeted MD simulation of conformational change - Application to the T-R transition in insulin
-
Schlitter, J., Engels, M., Krüger, P., Jacoby, E. & Wollmer, A. (1993). Targeted MD simulation of conformational change - application to the T-R transition in insulin. Mol. Simulation, 10, 291-308.
-
(1993)
Mol. Simulation
, vol.10
, pp. 291-308
-
-
Schlitter, J.1
Engels, M.2
Krüger, P.3
Jacoby, E.4
Wollmer, A.5
-
74
-
-
12044251259
-
Solvent suppression with symmetrically-shifted pulses
-
Smallcombe, S. H. (1993). Solvent suppression with symmetrically-shifted pulses. J. Am. Chem. Soc. 115, 4776-4785.
-
(1993)
J. Am. Chem. Soc.
, vol.115
, pp. 4776-4785
-
-
Smallcombe, S.H.1
-
77
-
-
0348219694
-
Structural stability in the 4-zinc human insulin hexamer
-
Smith, G. D., Swenson, D. C., Dodson, E. J., Dodson, G. G. & Reynolds, C. D. (1984). Structural stability in the 4-zinc human insulin hexamer. Proc. Natl Acad. Sci. USA, 22, 7093-7100.
-
(1984)
Proc. Natl Acad. Sci. USA
, vol.22
, pp. 7093-7100
-
-
Smith, G.D.1
Swenson, D.C.2
Dodson, E.J.3
Dodson, G.G.4
Reynolds, C.D.5
-
78
-
-
0027941825
-
Structural details of Asp(B9) human insulin at low pH from two-dimensional NMR titration studies
-
Sørensen, M. D. & Led, J. J. (1994). Structural details of Asp(B9) human insulin at low pH from two-dimensional NMR titration studies. Biochemistry, 33, 13727-13733.
-
(1994)
Biochemistry
, vol.33
, pp. 13727-13733
-
-
Sørensen, M.D.1
Led, J.J.2
-
79
-
-
2642628181
-
A two-dimensional nuclear Overhauser experiment with pure absorption phase in four quadrants
-
States, D. J., Haberkorn, R. A. & Ruben, D. J. (1982). A two-dimensional nuclear Overhauser experiment with pure absorption phase in four quadrants. J. Magn. Reson. 48, 386-393.
-
(1982)
J. Magn. Reson.
, vol.48
, pp. 386-393
-
-
States, D.J.1
Haberkorn, R.A.2
Ruben, D.J.3
-
80
-
-
1842357945
-
The biosynthesis of insulin
-
(Cuatrecasa, P. & Jacobs, S., eds), Springer-Verlag, Berlin, Germany
-
Steiner, D. F. (1990). The biosynthesis of insulin. In Insulin, Handbook of Experimental Pharmacology (Cuatrecasa, P. & Jacobs, S., eds), vol. 92, pp. 67-84. Springer-Verlag, Berlin, Germany.
-
(1990)
Insulin, Handbook of Experimental Pharmacology
, vol.92
, pp. 67-84
-
-
Steiner, D.F.1
-
81
-
-
38249034897
-
Interpretation of ring-current shifts in proteins: Application to phage X represser
-
Weiss, M. A. & Hoch, J. C. (1987). Interpretation of ring-current shifts in proteins: application to phage X represser. J. Magn. Reson. 72, 324-333.
-
(1987)
J. Magn. Reson.
, vol.72
, pp. 324-333
-
-
Weiss, M.A.1
Hoch, J.C.2
-
82
-
-
0024835166
-
Two-dimensional NMR and photo-CIDNP studies of the insulin monomer: Assignment of aromatic resonances with application to protein folding, structure and dynamics
-
Weiss, M. A., Nguyen, D. T., Khait, I., Inouye, K., Frank, B. M., Beckage, M., O'Shea, E., Shoelson, S. E., Karplus, M. & Neuringer, L. J. (1989). Two-dimensional NMR and photo-CIDNP studies of the insulin monomer: assignment of aromatic resonances with application to protein folding, structure and dynamics. Biochemistry, 28, 9855-9873.
-
(1989)
Biochemistry
, vol.28
, pp. 9855-9873
-
-
Weiss, M.A.1
Nguyen, D.T.2
Khait, I.3
Inouye, K.4
Frank, B.M.5
Beckage, M.6
O'Shea, E.7
Shoelson, S.E.8
Karplus, M.9
Neuringer, L.J.10
-
83
-
-
0024992662
-
NMR and photo-CIDNP studies of human proinsulin and prohormone processing intermediates with application to endopeptidase recognition
-
Weiss, M. A., Frank, B. H., Khait, A., Pekar, A., Heiney R., Shoelson, S. E. & Neuringer, L. J. (1990). NMR and photo-CIDNP studies of human proinsulin and prohormone processing intermediates with application to endopeptidase recognition. Biochemistry, 29, 8389-8401.
-
(1990)
Biochemistry
, vol.29
, pp. 8389-8401
-
-
Weiss, M.A.1
Frank, B.H.2
Khait, A.3
Pekar, A.4
Heiney, R.5
Shoelson, S.E.6
Neuringer, L.J.7
-
84
-
-
0011871162
-
Distinguishing symmetry-related intramolecular and intermolcular nuclear Overhauser effects in a protein by asymmetric isotopic labeling
-
Weiss, M. A. (1990). Distinguishing symmetry-related intramolecular and intermolcular nuclear Overhauser effects in a protein by asymmetric isotopic labeling. J. Magn. Reson. 86, 626-632.
-
(1990)
J. Magn. Reson.
, vol.86
, pp. 626-632
-
-
Weiss, M.A.1
-
86
-
-
0028849027
-
X-ray crystallographic studies on hexameric insulin in the presence of helix-stabilizing agents, thiocyanate, methylparaben and phenol
-
Whittingham, J. L., Chaudhuri, S., Dodson, E. J., Moody, P. C. E. & Dodson, G. G. (1995). X-ray crystallographic studies on hexameric insulin in the presence of helix-stabilizing agents, thiocyanate, methylparaben and phenol. Biochemistry, 34, 15553-15563.
-
(1995)
Biochemistry
, vol.34
, pp. 15553-15563
-
-
Whittingham, J.L.1
Chaudhuri, S.2
Dodson, E.J.3
Moody, P.C.E.4
Dodson, G.G.5
-
87
-
-
44949269218
-
Empirical comparison of models for chemical-shift calculation in proteins
-
Williamson, M. P. & Asakura, T. (1993). Empirical comparison of models for chemical-shift calculation in proteins. J. Magn. Reson. 101, 63-71.
-
(1993)
J. Magn. Reson.
, vol.101
, pp. 63-71
-
-
Williamson, M.P.1
Asakura, T.2
-
89
-
-
0026597879
-
The chemical shift index: A fast and simple method for the assignment of protein secondary structure through NMR spectroscopy
-
Wishart, D. S., Sykes, B. D. & Richards, F. M. (1992). The chemical shift index: a fast and simple method for the assignment of protein secondary structure through NMR spectroscopy. Biochemisty, 31, 1647-1651.
-
(1992)
Biochemisty
, vol.31
, pp. 1647-1651
-
-
Wishart, D.S.1
Sykes, B.D.2
Richards, F.M.3
-
90
-
-
0023278489
-
Phenol-promoted structural transformation of insulin in solution
-
Wollmer, A., Rannefeld, B., Johnsen, B. R., Hejnaes, K. R., Balschmidt, P. & Hansen, F. B. (1987). Phenol-promoted structural transformation of insulin in solution. Biol. Chem. Hoppe-Seyler, 368, 903-911.
-
(1987)
Biol. Chem. Hoppe-Seyler
, vol.368
, pp. 903-911
-
-
Wollmer, A.1
Rannefeld, B.2
Johnsen, B.R.3
Hejnaes, K.R.4
Balschmidt, P.5
Hansen, F.B.6
|