Hydrogen/deuterium exchange and mass spectrometric analysis of a protein containing multiple disulfide bonds: Solution structure of recombinant macrophage colony stimulating factor-beta (rhM-CSFβ)

Protein Science

Volumn 11, Issue 9, 2002, Pages 2113-2124

  Yan, Xuguang ^a   Zhang, Heidi ^a   Watson, Jeffrey ^a   Schimerlik, Michael I ^a   Deinzer, Max L ^a  

^a OREGON STATE UNIVERSITY   (United States)

Author keywords

Amide residue depth; Disulfide bonds; ESI MS; H D exchange; Macrophage colony stimulating factor

Indexed keywords

AMIDE; AMINO ACID; DEUTERIUM; HYDROGEN; ISOTOPE; RECOMBINANT COLONY STIMULATING FACTOR; SOLVENT; COLONY STIMULATING FACTOR 1; CYSTEINE; DISULFIDE; PEPTIDE; PROTEIN SUBUNIT; RECOMBINANT PROTEIN;

ALPHA HELIX; ARTICLE; BETA SHEET; CARBOXY TERMINAL SEQUENCE; CRYSTAL STRUCTURE; DISULFIDE BOND; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN STRUCTURE; X RAY CRYSTALLOGRAPHY; AMINO ACID SEQUENCE; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; PROTEIN CONFORMATION; TIME;

AMINO ACID SEQUENCE; CYSTEINE; DEUTERIUM; DISULFIDES; HUMAN; HYDROGEN; MACROPHAGE COLONY-STIMULATING FACTOR; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN CONFORMATION; PROTEIN SUBUNITS; RECOMBINANT PROTEINS; SOLVENTS; SPECTRUM ANALYSIS, MASS; SUPPORT, U.S. GOV'T, P.H.S.; TIME FACTORS; HUMANS; MASS SPECTROMETRY;

EID: 0036707994     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.0204402     Document Type: Article

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