-
1
-
-
0028943870
-
Design, synthesis, and structure-activity relationships of 2-substituted-2-amino-1,3-propanediols: Discovery of a novel immunosuppressant, FTY720
-
doi:10.1016/0960-894X(95)00127-F
-
Adachi K, Kohara T, Naka N, Arit M, Chiba K et al. (1995) Design, synthesis, and structure-activity relationships of 2-substituted-2-amino-1,3- propanediols: discovery of a novel immunosuppressant, FTY720. Biomed - Chem Lett 5: 853-856. doi:10.1016/0960-894X(95)00127-F.
-
(1995)
Biomed - Chem Lett
, vol.5
, pp. 853-856
-
-
Adachi, K.1
Kohara, T.2
Naka, N.3
Arit, M.4
Chiba, K.5
-
2
-
-
28044462458
-
FTY720, a new class of immunomodulator, inhibits lymphocyte egress from secondary lymphoid tissues and thymus by agonistic activity at sphingosine 1-phosphate receptors
-
doi:10.1016/j.pharmthera.2005.05.002. PubMed: 15951022
-
Chiba K (2005) FTY720, a new class of immunomodulator, inhibits lymphocyte egress from secondary lymphoid tissues and thymus by agonistic activity at sphingosine 1-phosphate receptors. Pharmacol Ther 108: 308-319. doi:10.1016/j.pharmthera.2005.05.002. PubMed: 15951022.
-
(2005)
Pharmacol Ther
, vol.108
, pp. 308-319
-
-
Chiba, K.1
-
3
-
-
0347481389
-
Phosphorylation of the immunomodulatory drug FTY720 by sphingosine kinases
-
doi:10.1074/jbc.M307687200. PubMed: 13129923
-
Billich A, Bornancin F, Dévay P, Mechtcheriakova D, Urtz N et al. (2003) Phosphorylation of the immunomodulatory drug FTY720 by sphingosine kinases. J Biol Chem 278: 47408-47415. doi:10.1074/jbc.M307687200. PubMed: 13129923.
-
(2003)
J Biol Chem
, vol.278
, pp. 47408-47415
-
-
Billich, A.1
Bornancin, F.2
Dévay, P.3
Mechtcheriakova, D.4
Urtz, N.5
-
4
-
-
33644697587
-
Effects of a novel immunomodulating agent, FTY720, on tumor growth and angiogenesis in hepatocellular carcinoma
-
doi:10.1158/1535-7163.MCT-05-0021. PubMed: 16170036
-
Ho JW, Man K, Sun CK, Lee TK, Poon RT et al. (2005) Effects of a novel immunomodulating agent, FTY720, on tumor growth and angiogenesis in hepatocellular carcinoma. Mol Cancer Ther 4: 1430-1438. doi:10.1158/1535-7163. MCT-05-0021. PubMed: 16170036.
-
(2005)
Mol Cancer Ther
, vol.4
, pp. 1430-1438
-
-
Ho, J.W.1
Man, K.2
Sun, C.K.3
Lee, T.K.4
Poon, R.T.5
-
5
-
-
28544451354
-
FTY720: A promising agent for treatment of metastatic hepatocellular carcinoma
-
doi:10.1158/1078-0432.CCR-05-0447. PubMed: 16322309
-
Lee TK, Man K, Ho JW, Wang XH, Poon RT et al. (2005) FTY720: a promising agent for treatment of metastatic hepatocellular carcinoma. Clin Cancer Res 11: 8458-8466. doi:10.1158/1078-0432.CCR-05-0447. PubMed: 16322309.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 8458-8466
-
-
Lee, T.K.1
Man, K.2
Ho, J.W.3
Wang, X.H.4
Poon, R.T.5
-
6
-
-
0034665512
-
Immunosuppressant FTY720 induces apoptosis by direct induction of permeability transition and release of cytochrome c from mitochondria
-
Baltimore, Md. : 1950 PubMed: 10975841
-
Nagahara Y, Ikekita M, Shinomiya T (2000) Immunosuppressant FTY720 induces apoptosis by direct induction of permeability transition and release of cytochrome c from mitochondria. J Immunol (Baltimore, Md. : 1950) 165: 3250-3259. PubMed: 10975841.
-
(2000)
J Immunol
, vol.165
, pp. 3250-3259
-
-
Nagahara, Y.1
Ikekita, M.2
Shinomiya, T.3
-
7
-
-
0036899017
-
T cell selective apoptosis by a novel immunosuppressant, FTY720, is closely regulated with Bcl-2
-
doi:10.1038/sj.bjp.0704970. PubMed: 12429567
-
Nagahara Y, Ikekita M, Shinomiya T (2002) T cell selective apoptosis by a novel immunosuppressant, FTY720, is closely regulated with Bcl-2. Br J Pharmacol 137: 953-962. doi:10.1038/sj.bjp.0704970. PubMed: 12429567.
-
(2002)
Br J Pharmacol
, vol.137
, pp. 953-962
-
-
Nagahara, Y.1
Ikekita, M.2
Shinomiya, T.3
-
8
-
-
0037051102
-
Anticarcinogenic effect of FTY720 in human prostate carcinoma DU145 cells: Modulation of mitogenic signaling, FAK, cell-cycle entry and apoptosis
-
doi:10.1002/ijc.10178. PubMed: 11857403
-
Permpongkosol S, Wang JD, Takahara S, Matsumiya K, Nonomura N et al. (2002) Anticarcinogenic effect of FTY720 in human prostate carcinoma DU145 cells: modulation of mitogenic signaling, FAK, cell-cycle entry and apoptosis. Int J Cancer 98: 167-172. doi:10.1002/ijc.10178. PubMed: 11857403.
-
(2002)
Int J Cancer
, vol.98
, pp. 167-172
-
-
Permpongkosol, S.1
Wang, J.D.2
Takahara, S.3
Matsumiya, K.4
Nonomura, N.5
-
9
-
-
0037739755
-
A novel immunosuppressive agent FTY720 induced Akt dephosphorylation in leukemia cells
-
doi:10.1038/sj.bjp.0705182. PubMed: 12711631
-
Matsuoka Y, Nagahara Y, Ikekita M, Shinomiya T (2003) A novel immunosuppressive agent FTY720 induced Akt dephosphorylation in leukemia cells. Br J Pharmacol 138: 1303-1312. doi:10.1038/sj.bjp.0705182. PubMed: 12711631.
-
(2003)
Br J Pharmacol
, vol.138
, pp. 1303-1312
-
-
Matsuoka, Y.1
Nagahara, Y.2
Ikekita, M.3
Shinomiya, T.4
-
10
-
-
0030794189
-
An immunosuppressive agent, FTY720, increases intracellular concentration of calcium ion and induces apoptosis in HL-60
-
doi:10.1046/j.1365-2567.1997.d01-2281.x. PubMed: 9378500
-
Shinomiya T, Li XK, Amemiya H, Suzuki S (1997) An immunosuppressive agent, FTY720, increases intracellular concentration of calcium ion and induces apoptosis in HL-60. Immunology 91: 594-600. doi:10.1046/j.1365-2567.1997.d01- 2281.x. PubMed: 9378500.
-
(1997)
Immunology
, vol.91
, pp. 594-600
-
-
Shinomiya, T.1
Li, X.K.2
Amemiya, H.3
Suzuki, S.4
-
11
-
-
84870200015
-
Molecular targets of FTY720 (fingolimod)
-
doi:10.2174/156652412803833599. PubMed: 22834825
-
Pitman MR, Woodcock JM, Lopez AF, Pitson SM (2012) Molecular targets of FTY720 (fingolimod). Curr Mol Med 12: 1207-1219. doi:10.2174/156652412803833599. PubMed: 22834825.
-
(2012)
Curr Mol Med
, vol.12
, pp. 1207-1219
-
-
Pitman, M.R.1
Woodcock, J.M.2
Lopez, A.F.3
Pitson, S.M.4
-
12
-
-
33846864904
-
The immunosuppressant drug FTY720 inhibits cytosolic phospholipase A2 independently of sphingosine-1-phosphate receptors
-
PubMed: 17008548
-
Payne SG, Oskeritzian CA, Griffiths R, Subramanian P, Barbour SE et al. (2007) The immunosuppressant drug FTY720 inhibits cytosolic phospholipase A2 independently of sphingosine-1-phosphate receptors. Blood 109: 1077-1085. PubMed: 17008548.
-
(2007)
Blood
, vol.109
, pp. 1077-1085
-
-
Payne, S.G.1
Oskeritzian, C.A.2
Griffiths, R.3
Subramanian, P.4
Barbour, S.E.5
-
13
-
-
0025643323
-
Complementation of the mitotic activator, p80cdc25, by a human protein-tyrosine phosphatase
-
doi:10.1126/science.1703321. PubMed: 1703321
-
Gould KL, Moreno S, Tonks NK, Nurse P (1990) Complementation of the mitotic activator, p80cdc25, by a human protein-tyrosine phosphatase. Science 250: 1573-1576. doi:10.1126/science.1703321. PubMed: 1703321.
-
(1990)
Science
, vol.250
, pp. 1573-1576
-
-
Gould, K.L.1
Moreno, S.2
Tonks, N.K.3
Nurse, P.4
-
14
-
-
0034157875
-
Mammalian tumor susceptibility gene 101 (TSG101) and the yeast homologue, Vps23p, both function in late endosomal trafficking
-
Copenhagen, Denmark
-
Babst M, Odorizzi G, Estepa EJ, Emr SD (2000) Mammalian tumor susceptibility gene 101 (TSG101) and the yeast homologue, Vps23p, both function in late endosomal trafficking. Traffic. (Copenhagen, Denmark) 1, 248-258.
-
(2000)
Traffic
, vol.1
, pp. 248-258
-
-
Babst, M.1
Odorizzi, G.2
Estepa, E.J.3
Emr, S.D.4
-
15
-
-
0033637063
-
Yeast mutants as a model system for identification of determinants of chemosensitivity
-
PubMed: 11121507
-
Perego P, Jimenez GS, Gatti L, Howell SB, Zunino F (2000) Yeast mutants as a model system for identification of determinants of chemosensitivity. Pharmacol Rev 52: 477-492. PubMed: 11121507.
-
(2000)
Pharmacol Rev
, vol.52
, pp. 477-492
-
-
Perego, P.1
Jimenez, G.S.2
Gatti, L.3
Howell, S.B.4
Zunino, F.5
-
16
-
-
0031845331
-
Sensitivity to cisplatin and platinum-containing compounds of Schizosaccharomyces pombe rad mutants
-
PubMed: 9658208
-
Perego P, Zunino F, Carenini N, Giuliani F, Spinelli S et al. (1998) Sensitivity to cisplatin and platinum-containing compounds of Schizosaccharomyces pombe rad mutants. Mol Pharmacol 54: 213-219. PubMed: 9658208.
-
(1998)
Mol Pharmacol
, vol.54
, pp. 213-219
-
-
Perego, P.1
Zunino, F.2
Carenini, N.3
Giuliani, F.4
Spinelli, S.5
-
17
-
-
0035985031
-
Calcineurin phosphatase in signal transduction: Lessons from fission yeast
-
doi:10.1046/j.1365-2443.2002.00557.x. PubMed: 12081640
-
Sugiura R, Sio SO, Shuntoh H, Kuno T (2002) Calcineurin phosphatase in signal transduction: lessons from fission yeast. Genes Cells 7: 619-627. doi:10.1046/j.1365-2443.2002.00557.x. PubMed: 12081640.
-
(2002)
Genes Cells
, vol.7
, pp. 619-627
-
-
Sugiura, R.1
Sio, S.O.2
Shuntoh, H.3
Kuno, T.4
-
18
-
-
2942536377
-
Yeast as a model system for anticancer drug discovery
-
doi:10.1038/nrc1372. PubMed: 15170450
-
Simon JA, Bedalov A (2004) Yeast as a model system for anticancer drug discovery. Nat Rev Cancer 4: 481-492. doi:10.1038/nrc1372. PubMed: 15170450.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 481-492
-
-
Simon, J.A.1
Bedalov, A.2
-
19
-
-
0038711709
-
Ubiquitin pathway proteins influence the mechanism of action of the novel immunosuppressive drug FTY720 in Saccharomyces cerevisiae
-
doi:10.1074/jbc.M213144200. PubMed: 12709439
-
Welsch CA, Hagiwara S, Goetschy JF, Movva NR (2003) Ubiquitin pathway proteins influence the mechanism of action of the novel immunosuppressive drug FTY720 in Saccharomyces cerevisiae. J Biol Chem 278: 26976-26982. doi:10.1074/jbc.M213144200. PubMed: 12709439.
-
(2003)
J Biol Chem
, vol.278
, pp. 26976-26982
-
-
Welsch, C.A.1
Hagiwara, S.2
Goetschy, J.F.3
Movva, N.R.4
-
20
-
-
4344650084
-
Genetic, biochemical, and transcriptional responses of Saccharomyces cerevisiae to the novel immunomodulator FTY720 largely mimic those of the natural sphingolipid phytosphingosine
-
doi:10.1074/jbc.M406179200. PubMed: 15190065
-
Welsch CA, Roth LW, Goetschy JF, Movva NR (2004) Genetic, biochemical, and transcriptional responses of Saccharomyces cerevisiae to the novel immunomodulator FTY720 largely mimic those of the natural sphingolipid phytosphingosine. J Biol Chem 279: 36720-36731. doi:10.1074/jbc.M406179200. PubMed: 15190065.
-
(2004)
J Biol Chem
, vol.279
, pp. 36720-36731
-
-
Welsch, C.A.1
Roth, L.W.2
Goetschy, J.F.3
Movva, N.R.4
-
21
-
-
0033779701
-
Calcineurin: Form and function
-
PubMed: 11015619
-
Rusnak F, Mertz P (2000) Calcineurin: form and function. Physiol Rev 80: 1483-1521. PubMed: 11015619.
-
(2000)
Physiol Rev
, vol.80
, pp. 1483-1521
-
-
Rusnak, F.1
Mertz, P.2
-
22
-
-
0036678476
-
Role of the Rab GTP-binding protein Ypt3 in the fission yeast exocytic pathway and its connection to calcineurin function
-
doi:10.1091/mbc.01-09-0463. PubMed: 12181359
-
Cheng H, Sugiura R, Wu W, Fujita M, Lu Y et al. (2002) Role of the Rab GTP-binding protein Ypt3 in the fission yeast exocytic pathway and its connection to calcineurin function. Mol Biol Cell 13: 2963-2976. doi:10.1091/mbc.01-09-0463. PubMed: 12181359.
-
(2002)
Mol Biol Cell
, vol.13
, pp. 2963-2976
-
-
Cheng, H.1
Sugiura, R.2
Wu, W.3
Fujita, M.4
Lu, Y.5
-
23
-
-
0029923979
-
+ gene encodes a novel mitogen-activated protein kinase homolog which regulates cell integrity and functions coordinately with the protein kinase C pathway
-
PubMed: 8943330
-
+ gene encodes a novel mitogen-activated protein kinase homolog which regulates cell integrity and functions coordinately with the protein kinase C pathway. Mol Cell Biol 16: 6752-6764. PubMed: 8943330.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 6752-6764
-
-
Toda, T.1
Dhut, S.2
Superti-Furga, G.3
Gotoh, Y.4
Nishida, E.5
-
24
-
-
0026025891
-
Molecular genetic analysis of fission yeast Schizosaccharomyces pombe
-
doi:10.1016/0076-6879(91)94059-L. PubMed: 2005825
-
Moreno S, Klar A, Nurse P (1991) Molecular genetic analysis of fission yeast Schizosaccharomyces pombe. Methods Enzymol 194: 795-823. doi:10.1016/0076-6879(91)94059-L. PubMed: 2005825.
-
(1991)
Methods Enzymol
, vol.194
, pp. 795-823
-
-
Moreno, S.1
Klar, A.2
Nurse, P.3
-
25
-
-
84876095698
-
Fingolimod phosphate attenuates oligomeric amyloid beta-induced neurotoxicity via increased brain-derived neurotrophic factor expression in neurons
-
doi:10.1371/journal.pone.0061988. PubMed: 23593505
-
Doi Y, Takeuchi H, Horiuchi H, Hanyu T, Kawanokuchi J et al. (2013) Fingolimod phosphate attenuates oligomeric amyloid beta-induced neurotoxicity via increased brain-derived neurotrophic factor expression in neurons. PLOS ONE 8: e61988. doi:10.1371/journal.pone.0061988. PubMed: 23593505.
-
(2013)
PLOS ONE
, vol.8
-
-
Doi, Y.1
Takeuchi, H.2
Horiuchi, H.3
Hanyu, T.4
Kawanokuchi, J.5
-
26
-
-
0038381464
-
- homeostasis in fission yeast. Identification of distinct branches of calcineurin signaling pathway in fission yeast
-
doi:10.1074/jbc.M212900200. PubMed: 12637524
-
- homeostasis in fission yeast. Identification of distinct branches of calcineurin signaling pathway in fission yeast. J Biol Chem 278: 18078-18084. doi:10.1074/jbc. M212900200. PubMed: 12637524.
-
(2003)
J Biol Chem
, vol.278
, pp. 18078-18084
-
-
Hirayama, S.1
Sugiura, R.2
Lu, Y.3
Maeda, T.4
Kawagishi, K.5
-
29
-
-
0036494268
-
Marked prevention of tumor growth and metastasis by a novel immunosuppressive agent, FTY720, in mouse breast cancer models
-
PubMed: 11888913
-
Azuma H, Takahara S, Ichimaru N, Wang JD, Itoh Y et al. (2002) Marked prevention of tumor growth and metastasis by a novel immunosuppressive agent, FTY720, in mouse breast cancer models. Cancer Res, 62: 621410-621419. PubMed: 11888913.
-
(2002)
Cancer Res
, vol.62
, pp. 621410-621419
-
-
Azuma, H.1
Takahara, S.2
Ichimaru, N.3
Wang, J.D.4
Itoh, Y.5
-
30
-
-
23844515685
-
FTY720 induces apoptosis in multiple myeloma cells and overcomes drug resistance
-
PubMed: 16103102
-
Yasui H, Hideshima T, Raje N, Roccaro AM, Shiraishi N et al. (2005) FTY720 induces apoptosis in multiple myeloma cells and overcomes drug resistance. Cancer Res, 65: 657478-657484. PubMed: 16103102.
-
(2005)
Cancer Res
, vol.65
, pp. 657478-657484
-
-
Yasui, H.1
Hideshima, T.2
Raje, N.3
Roccaro, A.M.4
Shiraishi, N.5
-
31
-
-
45749139274
-
Effects of phosphorylation of immunomodulatory agent FTY720 (fingolimod) on antiproliferative activity against breast and colon cancer cells
-
doi:10.1248/bpb.31.1177. PubMed: 18520051
-
Nagaoka Y, Otsuki K, Fujita T, Uesato S (2008) Effects of phosphorylation of immunomodulatory agent FTY720 (fingolimod) on antiproliferative activity against breast and colon cancer cells. Biol Pharm Bull 31: 1177-1181. doi:10.1248/bpb.31.1177. PubMed: 18520051.
-
(2008)
Biol Pharm Bull
, vol.31
, pp. 1177-1181
-
-
Nagaoka, Y.1
Otsuki, K.2
Fujita, T.3
Uesato, S.4
-
32
-
-
84859519656
-
Induction of brain tumor stem cell apoptosis by FTY720: A potential therapeutic agent for glioblastoma
-
doi:10.1093/neuonc/nos005. PubMed: 22351749
-
Estrada-Bernal A, Palanichamy K, Ray Chaudhury A, Van Brocklyn JR (2012) Induction of brain tumor stem cell apoptosis by FTY720: a potential therapeutic agent for glioblastoma. Neuro Oncol14: 405-415. doi:10.1093/neuonc/nos005. PubMed: 22351749.
-
(2012)
Neuro Oncol
, vol.14
, pp. 405-415
-
-
Estrada-Bernal, A.1
Palanichamy, K.2
Ray Chaudhury, A.3
Van Brocklyn, J.R.4
-
33
-
-
0033529578
-
Molecular identification of a eukaryotic, stretch-activated nonselective cation channel
-
doi:10.1126/science.285.5429.882. PubMed: 10436155
-
Kanzaki M, Nagasawa M, Kojima I, Sato C, Naruse K et al. (1999) Molecular identification of a eukaryotic, stretch-activated nonselective cation channel. Science 285: 882-886. doi:10.1126/science.285.5429.882. PubMed: 10436155.
-
(1999)
Science
, vol.285
, pp. 882-886
-
-
Kanzaki, M.1
Nagasawa, M.2
Kojima, I.3
Sato, C.4
Naruse, K.5
-
34
-
-
0037373333
-
FTY720 stimulates multidrug transporter- and cysteinyl leukotriene-dependent T cell chemotaxis to lymph nodes
-
doi:10.1172/JCI16200. PubMed: 12618517
-
Honig SM, Fu S, Mao X, Yopp A, Gunn MD et al. (2003) FTY720 stimulates multidrug transporter- and cysteinyl leukotriene-dependent T cell chemotaxis to lymph nodes. J Clin Invest 111: 627-637. doi:10.1172/JCI16200. PubMed: 12618517.
-
(2003)
J Clin Invest
, vol.111
, pp. 627-637
-
-
Honig, S.M.1
Fu, S.2
Mao, X.3
Yopp, A.4
Gunn, M.D.5
-
35
-
-
84862834834
-
The role of sphingosine-1-phosphate transporter Spns2 in immune system function
-
Baltimore, Md. : 1950 PubMed: 22664872
-
Nijnik A, Clare S, Hale C, Chen J, Raisen C et al. (2012) The role of sphingosine-1-phosphate transporter Spns2 in immune system function. J Immunol (Baltimore, Md. : 1950) 189: 102-111. PubMed: 22664872.
-
(2012)
J Immunol
, vol.189
, pp. 102-111
-
-
Nijnik, A.1
Clare, S.2
Hale, C.3
Chen, J.4
Raisen, C.5
-
36
-
-
84866929346
-
The functional roles of S1P in immunity
-
doi:10.1093/jb/mvs090. PubMed: 22923732
-
Hisano Y, Nishi T, Kawahara A (2012) The functional roles of S1P in immunity. J Biochem 152: 305-311. doi:10.1093/jb/mvs090. PubMed: 22923732.
-
(2012)
J Biochem
, vol.152
, pp. 305-311
-
-
Hisano, Y.1
Nishi, T.2
Kawahara, A.3
-
37
-
-
0028957971
-
+, a novel gene of Schizosaccharomyces pombe which confers brefeldin A resistance, is structurally related to the ATP-binding cassette superfamily
-
PubMed: 7883711
-
+, a novel gene of Schizosaccharomyces pombe which confers brefeldin A resistance, is structurally related to the ATP-binding cassette superfamily. J Bacteriol 177: 1536-1543. PubMed: 7883711.
-
(1995)
J Bacteriol
, vol.177
, pp. 1536-1543
-
-
Nagao, K.1
Taguchi, Y.2
Arioka, M.3
Kadokura, H.4
Takatsuki, A.5
-
38
-
-
0032523783
-
Regulation of the fission yeast transcription factor Pap1 by oxidative stress: Requirement for the nuclear export factor Crm1 (Exportin) and the stress-activated MAP kinase Sty1/Spc1
-
doi:10.1101/gad.12.10.1453. PubMed: 9585505
-
Toone WM, Kuge S, Samuels M, Morgan BA, Toda T et al. (1998) Regulation of the fission yeast transcription factor Pap1 by oxidative stress: requirement for the nuclear export factor Crm1 (Exportin) and the stress-activated MAP kinase Sty1/Spc1. Genes Dev 12: 1453-1463. doi:10.1101/gad.12.10.1453. PubMed: 9585505.
-
(1998)
Genes Dev
, vol.12
, pp. 1453-1463
-
-
Toone, W.M.1
Kuge, S.2
Samuels, M.3
Morgan, B.A.4
Toda, T.5
-
39
-
-
84859720894
-
Nonphosphorylated FTY720 induces apoptosis of human microglia by activating SREBP2
-
doi:10.1007/s10571-011-9698-x. PubMed: 21519925
-
Yoshino T, Tabunoki H, Sugiyama S, Ishii K, Kim SU et al. (2011) Nonphosphorylated FTY720 induces apoptosis of human microglia by activating SREBP2. Cell Mol Neurobiol 31: 1009-1020. doi:10.1007/s10571-011-9698-x. PubMed: 21519925.
-
(2011)
Cell Mol Neurobiol
, vol.31
, pp. 1009-1020
-
-
Yoshino, T.1
Tabunoki, H.2
Sugiyama, S.3
Ishii, K.4
Kim, S.U.5
-
40
-
-
77953694599
-
Sphingosine and FTY720 directly bind pro-survival 14-3-3 proteins to regulate their function
-
doi:10.1016/j.cellsig.2010.04.004. PubMed: 20403428
-
Woodcock JM, Ma Y, Coolen C, Pham D, Jones C et al. (2010) Sphingosine and FTY720 directly bind pro-survival 14-3-3 proteins to regulate their function. Cell Signal 22: 1291-1299. doi:10.1016/j.cellsig.2010.04.004. PubMed: 20403428.
-
(2010)
Cell Signal
, vol.22
, pp. 1291-1299
-
-
Woodcock, J.M.1
Ma, Y.2
Coolen, C.3
Pham, D.4
Jones, C.5
-
41
-
-
77949876964
-
Down-regulation of S1P1 receptor surface expression by protein kinase C inhibition
-
doi:10.1074/jbc.M109.049692. PubMed: 20032465
-
Sensken SC, Gräler MH (2010) Down-regulation of S1P1 receptor surface expression by protein kinase C inhibition. J Biol Chem 285: 6298-6307. doi:10.1074/jbc.M109.049692. PubMed: 20032465.
-
(2010)
J Biol Chem
, vol.285
, pp. 6298-6307
-
-
Sensken, S.C.1
Gräler, M.H.2
-
43
-
-
15744364484
-
Phosphorylation of sphingoid long-chain bases in Arabidopsis: Functional characterization and expression of the first sphingoid long-chain base Kinase gene in plants
-
doi:10.1093/pcp/pci023. PubMed: 15695468
-
Imai H, Nishiura H (2005) Phosphorylation of sphingoid long-chain bases in Arabidopsis: functional characterization and expression of the first sphingoid long-chain base Kinase gene in plants. Plant Cell Physiol 46: 375-380. doi:10.1093/pcp/pci023. PubMed: 15695468.
-
(2005)
Plant Cell Physiol
, vol.46
, pp. 375-380
-
-
Imai, H.1
Nishiura, H.2
-
44
-
-
18044380709
-
Systematic deletion analysis of fission yeast protein kinases
-
doi:10.1128/EC.4.4.799-813.2005. PubMed: 15821139
-
Bimbó A, Jia Y, Poh SL, Karuturi RK, den Elzen N et al. (2005) Systematic deletion analysis of fission yeast protein kinases. Eukaryot Cell 4: 799-813. doi:10.1128/EC.4.4.799-813.2005. PubMed: 15821139.
-
(2005)
Eukaryot Cell
, vol.4
, pp. 799-813
-
-
Bimbó, A.1
Jia, Y.2
Poh, S.L.3
Karuturi, R.K.4
Den Elzen, N.5
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