Ginsenoside Rd promotes glutamate clearance by up-regulating glial glutamate transporter GLT-1 via PI3K/AKT and ERK1/2 pathways

Frontiers in Pharmacology

Volumn 4 DEC, Issue , 2013, Pages

  Zhang, Xiao ^a   Shi, Ming ^a   Bjørås, Magnar ^b   Wang, Wei ^b   Zhang, Guangyun ^a   Han, Junliang ^a   Liu, Zhirong ^a   Zhang, Yunxia ^a   Wang, Bing ^a   Chen, Jing ^a   Zhu, Yi ^a   Xiong, Lize ^a   Zhao, Gang ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

Astrocyte; ERK1 2; Ginsenoside Rd; GLT 1; Glutamate; PI3K AKT

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; GINSENOSIDE RD; GLUCOSE; GLUTAMIC ACID; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; OXYGEN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; VESICULAR GLUTAMATE TRANSPORTER 1;

AMINO ACID METABOLISM; AMINO ACID TRANSPORT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASTROCYTE CULTURE; CONTROLLED STUDY; IN VITRO STUDY; IN VIVO STUDY; MALE; MICRODIALYSIS; MIDDLE CEREBRAL ARTERY OCCLUSION; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; UPREGULATION;

EID: 84891704489     PISSN: None     EISSN: 16639812     Source Type: Journal    
DOI: 10.3389/fphar.2013.00152     Document Type: Article

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