Targeted over-expression of glutamate transporter 1 (GLT-1) reduces ischemic brain injury in a rat model of stroke

PLoS ONE

Volumn 6, Issue 8, 2011, Pages

  Harvey, Brandon K ^a   Airavaara, Mikko ^a   Hinzman, Jason ^b   Wires, Emily M ^a   Chiocco, Matthew J ^a   Howard, Douglas B ^a   Shen, Hui ^a   Gerhardt, Greg ^b   Hoffer, Barry J ^a   Wang, Yun ^a  

^a NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; PARVOVIRUS VECTOR; TRIPHENYLTETRAZOLIUM; VESICULAR GLUTAMATE TRANSPORTER 1; GLUTAMATE TRANSPORTER; GLUTAMIC ACID DERIVATIVE;

AMPEROMETRY; ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BEHAVIORAL SCIENCE; BRAIN DAMAGE; BRAIN INFARCTION; BRAIN ISCHEMIA; CONTROLLED STUDY; DNA FRAGMENTATION; DRUG MECHANISM; GENE EXPRESSION; GENE OVEREXPRESSION; IN VIVO STUDY; MICRODIALYSIS; MIDDLE CEREBRAL ARTERY OCCLUSION; NERVE CELL NECROSIS; NEUROPROTECTION; NICK END LABELING; NONHUMAN; RISK REDUCTION; TASK PERFORMANCE; VIRAL GENE DELIVERY SYSTEM; ADENO ASSOCIATED VIRUS; ANIMAL; BRAIN CORTEX; BRAIN INJURY; CELL STRAIN HEK293; CEREBRAL ARTERY DISEASE; CONVALESCENCE; DISEASE MODEL; FISCHER 344 RAT; GENE EXPRESSION REGULATION; HUMAN; MALE; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; RAT; STROKE;

ANIMALIA; RATTUS;

AMINO ACID TRANSPORT SYSTEM X-AG; ANIMALS; BEHAVIOR, ANIMAL; BRAIN INFARCTION; BRAIN INJURIES; BRAIN ISCHEMIA; CEREBRAL CORTEX; DEPENDOVIRUS; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; GLUTAMATES; HEK293 CELLS; HUMANS; IN SITU NICK-END LABELING; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; RATS; RATS, INBRED F344; RECOVERY OF FUNCTION; STROKE;

EID: 80051529968     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0022135     Document Type: Article

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