Neuregulin1β1 protects oligodendrocyte progenitor cells from oxygen glucose deprivation injury induced apoptosis via ErbB4-dependent activation of PI3-kinase/Akt

Brain Research

Volumn 1467, Issue , 2012, Pages 104-112

  Xu, Chongchong ^a   Lv, Lei ^b   Zheng, Guoli ^a   Li, Beiya ^a   Gao, Lu ^a   Sun, Yan ^a  

^a FUDAN UNIVERSITY   (China)

^b FUDAN UNIVERSITY   (China)

Author keywords

ErbB4; Neuregulin1 1; Oligodendrocyte progenitor cells; Periventricular white matter injury; PI3 kinase Akt pathway

Indexed keywords

CASPASE 3; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIDERMAL GROWTH FACTOR RECEPTOR 4; GLUCOSE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; MITOGEN ACTIVATED PROTEIN KINASE; NEU DIFFERENTIATION FACTOR; NEUREGULIN1BETA1; NEUROPROTECTIVE AGENT; OXYGEN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; RECOMBINANT HUMAN NEUREGULIN1BETA1; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; BRAIN INJURY; CELL HYPOXIA; CONTROLLED STUDY; DRUG MECHANISM; DRUG RECEPTOR BINDING; EMBRYO; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GENE EXPRESSION REGULATION; NEURAL STEM CELL; NEUROPROTECTION; NONHUMAN; OLIGODENDROCYTE PROGENITOR CELL; PERIVENTRICULAR WHITE MATTER INJURY; PRIORITY JOURNAL; PROTEIN DOMAIN; RAT; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; WHITE MATTER;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CASPASE 3; CELL HYPOXIA; CELL SURVIVAL; ENZYME ACTIVATION; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GLUCOSE; NEUREGULIN-1; OLIGODENDROGLIA; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, WISTAR; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION; STEM CELLS;

EID: 84863984742     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2012.05.044     Document Type: Article

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