Stiffness and adhesivity control aortic valve interstitial cell behavior within hyaluronic acid based hydrogels

Acta Biomaterialia

Volumn 9, Issue 8, 2013, Pages 7640-7650

  Duan, Bin ^a   Hockaday, Laura A ^a   Kapetanovic, Edi ^b   Kang, Kevin H ^a   Butcher, Jonathan T ^a  

^a School of Chemical and Molecular Engineering   (United States)

^b Department of Molecular Biology and Genetics   (United States)

Author keywords

Cell spreading; Microenvironment; Phenotype; Stiffness; Tissue engineering

Indexed keywords

CELL ENGINEERING; CYTOLOGY; ENZYME ACTIVITY; HYALURONIC ACID; HYDROGELS; ORGANIC ACIDS; RATIONAL FUNCTIONS; SCAFFOLDS (BIOLOGY); TISSUE;

ADHESIVITY; CELL BEHAVIOURS; CELL SPREADING; HYBRID HYDROGELS; MECHANICAL STIFFNESS; METHACRYLATED HYALURONIC ACIDS; MICROENVIRONMENTS; PHENOTYPE; TISSUES ENGINEERINGS; VALVE INTERSTITIAL CELLS;

STIFFNESS;

ALPHA SMOOTH MUSCLE ACTIN; GELATIN; HYALURONIC ACID; HYALURONIDASE; METHACRYLIC ACID; TRANSCRIPTION FACTOR RUNX2; VIMENTIN; HYDROGEL;

ANIMAL CELL; AORTA VALVE; ARTICLE; BIOMECHANICS; CELL ADHESION; CELL ENCAPSULATION; CELL MIGRATION; CELL PROLIFERATION; CELL SPREADING; CELL STRUCTURE; CELL TYPE; CELL VIABILITY; CHEMICAL COMPOSITION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; HYDROGEL; IMMUNOHISTOCHEMISTRY; MOLECULAR WEIGHT; MYOFIBROBLAST; NONHUMAN; OXIDATION; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RIGIDITY; SYNTHESIS; TISSUE ENGINEERING; UPREGULATION; VALVE INTERSTITIAL CELL; WETTABILITY; ANIMAL; CELL CULTURE; CELL MOTION; CYTOLOGY; MECHANICAL STRESS; METHODOLOGY; PHYSIOLOGY; SWINE; YOUNG MODULUS; PROCEDURES;

ANIMALS; AORTIC VALVE; CELL ADHESION; CELL MOVEMENT; CELLS, CULTURED; ELASTIC MODULUS; HYALURONIC ACID; HYDROGELS; STRESS, MECHANICAL; SWINE; TISSUE ENGINEERING;

EID: 84891684495     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2013.04.050     Document Type: Article

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