Cyclic strain anisotropy regulates valvular interstitial cell phenotype and tissue remodeling in three-dimensional culture

Acta Biomaterialia

Volumn 8, Issue 5, 2012, Pages 1710-1719

  Gould, Russell A ^a   Chin, Karen ^a   Santisakultarm, Thom P ^a   Dropkin, Amanda ^a   Richards, Jennifer M ^a   Schaffer, Chris B ^a   Butcher, Jonathan T ^a  

^a School of Chemical and Molecular Engineering   (United States)

Author keywords

Bioreactor; Fibroblast; Heart valve; Tissue engineering; Wound healing

Indexed keywords

ANISOTROPY; BIOREACTORS; CELL CULTURE; CELL DEATH; CELL ENGINEERING; CELL PROLIFERATION; FIBROBLASTS; HISTOLOGY; MUSCLE; TISSUE ENGINEERING;

BIOREACTOR; CELL PHENOTYPE; CYCLIC STRAIN; FIBROBLAST; HEART VALVES; INTERSTITIALS; STRAIN ANISOTROPIES; STRAIN FIELDS; TISSUES ENGINEERINGS; WOUND HEALING;

COLLAGEN;

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN FIBER; VIMENTIN;

ANIMAL CELL; ANISOTROPY; AORTA VALVE; AORTA VALVE INTERSTITIAL CELL; APOPTOSIS; ARTICLE; BIOREACTOR DESIGN; CELL PROLIFERATION; CELL TYPE; CONTROLLED STUDY; CYCLIC STRAIN ANISOTROPY; EXTRACELLULAR MATRIX; FIBROBLAST; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REACTOR OPTIMIZATION; STRESS STRAIN RELATIONSHIP; TISSUE ENGINEERING;

EID: 84859110665     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2012.01.006     Document Type: Article

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