Mitral valvular interstitial cell responses to substrate stiffness depend on age and anatomic region

Acta Biomaterialia

Volumn 7, Issue 1, 2011, Pages 75-82

  Stephens, Elizabeth H ^a   Durst, Christopher A ^a   West, Jennifer L ^a   Grande Allen, K Jane ^a  

^a Rice University   (United States)

Author keywords

Age aging; Heart valve; Hydrogel; Stiffness; Surface modification

Indexed keywords

BIOSYNTHESIS; ETHYLENE; HYDROGELS; PROTEINS; STIFFNESS MATRIX; SUBSTRATES; SURFACE TREATMENT; VALVES (MECHANICAL);

AGE/AGING; ANATOMIC REGIONS; CELL PHENOTYPE; HEART VALVES; HEAT SHOCK PROTEIN; INTERSTITIALS; PROLYL-4-HYDROXYLASE; SMOOTH MUSCLES; SUBSTRATE STIFFNESS; SURFACE-MODIFICATION;

STIFFNESS;

ALPHA SMOOTH MUSCLE ACTIN; ARGINYLGLYCYLASPARTYLSERINE; BIOLOGICAL MARKER; COLLAGEN; HEAT SHOCK PROTEIN 47; HEPARIN DERIVATIVE; MACROGOL; METHACRYLIC ACID DERIVATIVE; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; VIMENTIN;

AGING; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL CULTURE; CELL STRUCTURE; CELLULAR DISTRIBUTION; COLLAGEN SYNTHESIS; EXTRACELLULAR MATRIX; GROUPS BY AGE; HEART MUSCLE CELL; HYDROGEL; IMMUNOCYTOCHEMISTRY; MITRAL VALVE; NONHUMAN; PHENOTYPE; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REACTION OPTIMIZATION; RIGIDITY; SWINE; SYNTHESIS; YOUNG MODULUS;

SUS;

EID: 78049420977     PISSN: 17427061     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.actbio.2010.07.001     Document Type: Article

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