Pharmacogenetics: Implications of race and ethnicity on defining genetic profiles for personalized medicine

Journal of Allergy and Clinical Immunology

Volumn 133, Issue 1, 2014, Pages 16-26

  Ortega, Victor E ^a   Meyers, Deborah A ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

admixture mapping; Asthma; ethnic group; genes; pharmacogenetics; response heterogeneity; single nucleotide polymorphism

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR BLOCKING AGENT; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; BUDESONIDE; FLUNISOLIDE; FLUTICASONE; FORMOTEROL; MONTELUKAST; SALBUTAMOL; SALMETEROL; TRIAMCINOLONE; ZILEUTON;

AMERICAN INDIAN; ARTICLE; ASTHMA; CODING; ETHNIC GROUP; ETHNICITY; EUROPE; GENE; GENE INTERACTION; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOME; HAPLOTYPE; HUMAN; PALEOLITHIC; PERSONALIZED MEDICINE; PHARMACOGENETICS; PHENOTYPE; PRIORITY JOURNAL; RACE;

ADMIXTURE MAPPING; ADRB1; ADRB2; ASTHMA; BADGER; BARGE; BEST ADD-ON THERAPY GIVING EFFECTIVE RESPONSE TRIAL; BETA AGONIST RESPONSE BY GENOTYPE TRIAL; CAAPA; CONSORTIUM ON ASTHMA AMONG AFRICAN-ANCESTRY POPULATIONS IN THE AMERICAS; ETHNIC GROUP; G PROTEIN RECEPTOR KINASE 5; GALA; GENES; GENETICS OF ASTHMA IN LATINO AMERICANS; GENOME-WIDE ASSOCIATION STUDY; GLCCL1; GLUCOCORTICOID-INDUCED TRANSCRIPT 1 GENE; GRK5; GWAS; ICS; INHALED CORTICOSTEROID; LABA; LARGE; LONG-ACTING BETA AGONIST RESPONSE BY GENOTYPE; LONG-ACTING Β-AGONIST; NATIONAL HEART, LUNG, AND BLOOD INSTITUTE; NATIONAL INSTITUTES OF HEALTH; NHLBI; NIH; PEAK EXPIRATORY FLOW RATE; PEFR; PHARMACOGENETICS; RESPONSE HETEROGENEITY; SABA; SALMETEROL MULTICENTER ASTHMA RESEARCH TRIAL; SHORT-ACTING Β-AGONIST; SINGLE NUCLEOTIDE POLYMORPHISM; SMART; SNP; SPATS2L; SPERMATOGENESIS-ASSOCIATED, SERINE-RICH 2-LIKE GENE; Β(1)-ADRENERGIC RECEPTOR; Β(2)-ADRENERGIC RECEPTOR;

ADRENERGIC BETA-AGONISTS; ADULT; ASTHMA; EUROPEAN CONTINENTAL ANCESTRY GROUP; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HISPANIC AMERICANS; HUMANS; INDIVIDUALIZED MEDICINE; PHARMACOGENETICS; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, ADRENERGIC, BETA-2;

EID: 84891671739     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2013.10.040     Document Type: Review

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