Genome-wide association identifies the T gene as a novel asthma pharmacogenetic locus

American Journal of Respiratory and Critical Care Medicine

Volumn 185, Issue 12, 2012, Pages 1286-1291

  Tantisira, Kelan G ^a   Damask, Amy ^b   Szefler, Stanley J ^c   Schuemann, Brooke ^a   Markezich, Amy ^d   Su, Jessica ^a   Klanderman, Barbara ^e   Sylvia, Jody ^a   Wu, Rongling ^f   Martinez, Fernando ^g   Boushey, Homer A ^h   Chinchilli, Vernon M ^f   Mauger, Dave ^f   Weiss, Scott T ^a,e   Israel, Elliot ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b Novartis Corporation   (United States)

^c Children's Hospital Colorado   (United States)

^d Overlake Internal Medicine Associates   (United States)

^e LABORATORY FOR MOLECULAR MEDICINE   (United States)

^f PENN STATE COLLEGE OF MEDICINE   (United States)

^g UNIVERSITY OF ARIZONA   (United States)

^h UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Genome; Glucocorticoid; Pharmacogenomics; Polymorphism

Indexed keywords

CORTICOSTEROID;

ADULT; ARTICLE; ASTHMA; CONTROLLED STUDY; FEMALE; GENE; GENE IDENTIFICATION; GENE LOCUS; GENETIC ASSOCIATION; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; PHARMACOGENETICS; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; T GENE;

ADOLESCENT; ADRENAL CORTEX HORMONES; ADULT; ALLELES; ASTHMA; CHILD; CHILD, PRESCHOOL; FEMALE; FETAL PROTEINS; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMANS; MALE; MIDDLE AGED; MOLECULAR TARGETED THERAPY; PHARMACOGENETICS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROGNOSIS; RESPIRATORY FUNCTION TESTS; RISK ASSESSMENT; SEVERITY OF ILLNESS INDEX; T-BOX DOMAIN PROTEINS; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84862585029     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201111-2061OC     Document Type: Article

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