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Volumn 8, Issue 4, 1998, Pages 283-289

Hypothesis: Comparisons of inter- and intra-individual variations can substitute for twin studies in drug research

Author keywords

Genetic component; Heritability; Repeat studies; Variations

Indexed keywords

ACYLTRANSFERASE; ALCOHOL; CAFFEINE; CYTOCHROME P450 ISOENZYME; DEXTROMETHORPHAN; OXAZEPAM; PHENACETIN O DEETHYLASE; XANTHINE OXIDASE;

EID: 0031826288     PISSN: 0960314X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008571-199808000-00001     Document Type: Review
Times cited : (269)

References (36)
  • 2
    • 0029971627 scopus 로고    scopus 로고
    • Validation of urine caffeine metabolite ratios with use of stable isotope-labeled caffeine clearance
    • Denaro CP, Wilson M, Jacob III P, Benowitz NL. Validation of urine caffeine metabolite ratios with use of stable isotope-labeled caffeine clearance. Clin Pharmacol Ther 1996; 59:284-296.
    • (1996) Clin Pharmacol Ther , vol.59 , pp. 284-296
    • Denaro, C.P.1    Wilson, M.2    Jacob III, P.3    Benowitz, N.L.4
  • 3
    • 0029146538 scopus 로고
    • Antidepressant drug interactions and the cytochrome P450 system
    • Ereshefsky L, Riesenman C, Lam YWF. Antidepressant drug interactions and the cytochrome P450 system. Clin Pharmacokinet 1995; 29 (suppl 1): 10-19.
    • (1995) Clin Pharmacokinet , vol.29 , Issue.1 SUPPL. , pp. 10-19
    • Ereshefsky, L.1    Riesenman, C.2    Lam, Y.W.F.3
  • 5
    • 0029099107 scopus 로고
    • A genetic polymorphism in coumarin 7-hydroxylation: Sequence of the human CYP2A genes and identification of variant CYP2A6 alleles
    • Fernandez-Salguero P, Hoffman SMG, Cholerton S et al. A genetic polymorphism in coumarin 7-hydroxylation: sequence of the human CYP2A genes and identification of variant CYP2A6 alleles. Am J Hum Genet 1995; 57:651-660.
    • (1995) Am J Hum Genet , vol.57 , pp. 651-660
    • Fernandez-Salguero, P.1    Hoffman, S.M.G.2    Cholerton, S.3
  • 6
    • 0028792443 scopus 로고
    • Inter-individual and intra-individual variability of ethanol concentration-time profiles: Comparison of ethanol ingestion before and after an evening meal
    • Fraser AG, Rosalki SB, Gamble GD, Pounder RE. Inter-individual and intra-individual variability of ethanol concentration-time profiles: comparison of ethanol ingestion before and after an evening meal. Br J Clin Pharmacol 1995; 40:387-392.
    • (1995) Br J Clin Pharmacol , vol.40 , pp. 387-392
    • Fraser, A.G.1    Rosalki, S.B.2    Gamble, G.D.3    Pounder, R.E.4
  • 7
    • 0011260466 scopus 로고
    • The history of twins as a criterium of the relative powers of nature and nurture
    • Galton R. The history of twins as a criterium of the relative powers of nature and nurture. J Anthropol Inst 1876; 5:391-406.
    • (1876) J Anthropol Inst , vol.5 , pp. 391-406
    • Galton, R.1
  • 8
    • 0026849441 scopus 로고
    • Biotransformation of caffeine, paraxanthine, theobromine and theophylline by cDNA-expressed human CYP1A2 and CYP2E1
    • Gu L, Gonzalez FJ, Kalow W, Tang BK. Biotransformation of caffeine, paraxanthine, theobromine and theophylline by cDNA-expressed human CYP1A2 and CYP2E1. Pharmacogenetics 1992; 2:73-77.
    • (1992) Pharmacogenetics , vol.2 , pp. 73-77
    • Gu, L.1    Gonzalez, F.J.2    Kalow, W.3    Tang, B.K.4
  • 9
    • 0002636651 scopus 로고    scopus 로고
    • Pharmacokinetics of ethanol: Absorption, distribution, and elimination
    • Begleiter H, Kissin B, editors. New York, Oxford. Oxford University Press
    • Kalant H. Pharmacokinetics of ethanol: absorption, distribution, and elimination. In: Begleiter H, Kissin B, editors. The pharmacology of alcohol and alcohol dependence. New York, Oxford. Oxford University Press; 1996. pp. 15-58.
    • (1996) The Pharmacology of Alcohol and Alcohol Dependence , pp. 15-58
    • Kalant, H.1
  • 10
    • 6844238138 scopus 로고    scopus 로고
    • Continuous versus polymorphic variation - Practical aspects
    • Schlegel J, Hori W, editors. Southborough, MA: IBC Biomedical Library Series
    • Kalow W. Continuous versus polymorphic variation - practical aspects. In: Schlegel J, Hori W, editors. Pharmacogenetics. Bridging the gap between basic science and clinical application. Southborough, MA: IBC Biomedical Library Series; 1996. pp. 4.2.1-4.2.18.
    • (1996) Pharmacogenetics. Bridging the Gap between Basic Science and Clinical Application , pp. 421-4218
    • Kalow, W.1
  • 11
    • 0026094528 scopus 로고
    • Use of caffeine metabolite ratios to explore CYP1A2 and xanthine oxidase activities
    • Kalow W, Tang BK. Use of caffeine metabolite ratios to explore CYP1A2 and xanthine oxidase activities. Clin Pharmacol Ther 1991; 50:508-519.
    • (1991) Clin Pharmacol Ther , vol.50 , pp. 508-519
    • Kalow, W.1    Tang, B.K.2
  • 12
    • 0027197152 scopus 로고
    • The use of caffeine for enzyme assays: A critical apraisal
    • Kalow W, Tang BK. The use of caffeine for enzyme assays: a critical apraisal. Clin Pharmacol Ther 1993; 53:503-514.
    • (1993) Clin Pharmacol Ther , vol.53 , pp. 503-514
    • Kalow, W.1    Tang, B.K.2
  • 13
    • 0017410391 scopus 로고
    • The kinetics of ethanol absorption and elimination in twins and supplementary repetitive experiments in singleton subjects
    • Kopun M, Propping P. The kinetics of ethanol absorption and elimination in twins and supplementary repetitive experiments in singleton subjects. Eur J Clin Pharmacol 1977; 11:337-344.
    • (1977) Eur J Clin Pharmacol , vol.11 , pp. 337-344
    • Kopun, M.1    Propping, P.2
  • 16
    • 0021844841 scopus 로고
    • Polymorphism of theophylline metabolism in man
    • Miller CA, Slusher LB, Vesell ES. Polymorphism of theophylline metabolism in man. J Clin Invest 1985; 75:1415-1425.
    • (1985) J Clin Invest , vol.75 , pp. 1415-1425
    • Miller, C.A.1    Slusher, L.B.2    Vesell, E.S.3
  • 19
    • 0025253097 scopus 로고
    • Reproducibility of individual rates of ethanol metabolism in fasting subjects
    • Passananti GT, Wolff CA, Vesell ES. Reproducibility of individual rates of ethanol metabolism in fasting subjects. Clin Pharmacol Ther 1990; 47:389-396.
    • (1990) Clin Pharmacol Ther , vol.47 , pp. 389-396
    • Passananti, G.T.1    Wolff, C.A.2    Vesell, E.S.3
  • 21
    • 0028811175 scopus 로고
    • Interindividual variability in the glucuronidation of (S) oxazepam contrasted with that of (R) oxazepam
    • Patel M, Tang BK, Grant DM, Kalow W. Interindividual variability in the glucuronidation of (S) oxazepam contrasted with that of (R) oxazepam. Pharmacogenetics 1995; 5:287-297.
    • (1995) Pharmacogenetics , vol.5 , pp. 287-297
    • Patel, M.1    Tang, B.K.2    Grant, D.M.3    Kalow, W.4
  • 23
    • 0023687412 scopus 로고
    • A form of cytochrome P450 in man, orthologous to form d in the rat, catalyses the O-deethylation of phenacetin and is inducible by cigarette smoking
    • Sesardic D, Boobis AR, Edwards RJ, Davies DS. A form of cytochrome P450 in man, orthologous to form d in the rat, catalyses the O-deethylation of phenacetin and is inducible by cigarette smoking. Br J Clin Pharmacol 1988; 26:363-372.
    • (1988) Br J Clin Pharmacol , vol.26 , pp. 363-372
    • Sesardic, D.1    Boobis, A.R.2    Edwards, R.J.3    Davies, D.S.4
  • 24
    • 0014034483 scopus 로고
    • Acetophenetidin sensitivity
    • Shahidi NT. Acetophenetidin sensitivity. Am J Dis Child 1967; 113:81-82.
    • (1967) Am J Dis Child , vol.113 , pp. 81-82
    • Shahidi, N.T.1
  • 28
    • 0025892853 scopus 로고
    • Caffeine as a metabolic probe: Validation for its use for acetylator phenotyping
    • Tang BK, Kadar D, Li Qian, Iriah J, Yip J, Kalow W. Caffeine as a metabolic probe: validation for its use for acetylator phenotyping. Clin Pharmacol Ther 1991; 49:648-657.
    • (1991) Clin Pharmacol Ther , vol.49 , pp. 648-657
    • Tang, B.K.1    Kadar, D.2    Qian, L.3    Iriah, J.4    Yip, J.5    Kalow, W.6
  • 29
    • 0028333956 scopus 로고
    • Caffeine as a probe for CYP1A2 activity: Potential influence of renal factors on urinary phenotypic trait measurements
    • Tang BR, Zhou Y, Radar D, Kalow W. Caffeine as a probe for CYP1A2 activity: potential influence of renal factors on urinary phenotypic trait measurements. Pharmacogenetics 1994; 4:117-124.
    • (1994) Pharmacogenetics , vol.4 , pp. 117-124
    • Tang, B.R.1    Zhou, Y.2    Radar, D.3    Kalow, W.4
  • 30
    • 7344266187 scopus 로고
    • Multifactorial Inheritance
    • Philadelphia: WB Saunders Company
    • Thompson JS, Thompson MW. Multifactorial Inheritance. In: Genetics in medicine. Philadelphia: WB Saunders Company; 1986. pp. 210-225.
    • (1986) Genetics in Medicine , pp. 210-225
    • Thompson, J.S.1    Thompson, M.W.2
  • 32
    • 0015025833 scopus 로고
    • Genetic and environmental factors afffecting ethanol metabolism in man
    • Vesell ES, Page JG, Passananti GT. Genetic and environmental factors afffecting ethanol metabolism in man. Clin Pharmacol Ther 1971; 12:192-201.
    • (1971) Clin Pharmacol Ther , vol.12 , pp. 192-201
    • Vesell, E.S.1    Page, J.G.2    Passananti, G.T.3
  • 34
    • 0001407146 scopus 로고
    • Beitraege zur Physiologie und Pathologie der Mehrlingsgeburten beim Menschen
    • Weinberg W. Beitraege zur Physiologie und Pathologie der Mehrlingsgeburten beim Menschen. Arch Ges Physiol 1901; 88:346-430.
    • (1901) Arch Ges Physiol , vol.88 , pp. 346-430
    • Weinberg, W.1
  • 35
    • 0018842748 scopus 로고
    • Pharmacokinetics of ethanol: A review
    • Wilkinson PR. Pharmacokinetics of ethanol: a review. Alcoholism: Clin Exp Res 1980; 4:6-21.
    • (1980) Alcoholism: Clin Exp Res , vol.4 , pp. 6-21
    • Wilkinson, P.R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.