Impaired hippocampal acetylcholine release parallels spatial memory deficits in Tg2576 mice subjected to basal forebrain cholinergic degeneration

Brain Research

Volumn 1543, Issue , 2014, Pages 253-262

  Laursen, Bettina ^a,b   Mørk, Arne ^a   Plath, Niels ^a   Kristiansen, Uffe ^b   Frank Bastlund, Jesper ^a  

^a H LUNDBECK A S   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Acetylcholine; Alzheimer's disease; Cognitive deficit; Mu p75 saporin; Tg2576

Indexed keywords

ACETYLCHOLINE; AMYLOID BETA PROTEIN; CHOLINE ACETYLTRANSFERASE; IMMUNOTOXIN; PROTEIN P75; SAPORIN;

ACETYLCHOLINE RELEASE; ALZHEIMER DISEASE; AMNESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN DEGENERATION; COGNITIVE DEFECT; CONTROLLED STUDY; FOREBRAIN; FRONTAL CORTEX; HIPPOCAMPUS; LONG TERM MEMORY; MALE; MICRODIALYSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPATIAL MEMORY; WORKING MEMORY;

ACETYLCHOLINE; ACH; AD; ALZHEIMER'S DISEASE; AMYLOID BETA; AMYLOID PRECURSOR PROTEIN; APP; AΒ; BASAL FOREBRAIN CHOLINERGIC DEGENERATION; BFCD; CHAT; CHOLINE ACETYLTRANSFERASE; COGNITIVE DEFICIT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HPLC; ICV; INTRACEREBROVENTRICULAR; M2R; MU P75-SAPORIN; MUSCARINIC ACETYLCHOLINE RECEPTOR 2; PRESENILIN 1; PRESENILIN 2; PS1; PS2; SAP; T-CAT; T-MAZE CONTINUOUS ALTERNATION TASK.; TG2576; WILD TYPE LITTERMATE; WT;

ACETYLCHOLINE; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CHOLINE O-ACETYLTRANSFERASE; CHOLINERGIC NEURONS; DISEASE MODELS, ANIMAL; HIPPOCAMPUS; HUMANS; IMMUNOTOXINS; MAZE LEARNING; MEMORY DISORDERS; MICE; MICE, TRANSGENIC; NERVE DEGENERATION; PRESENILIN-1; PROSENCEPHALON; RECOGNITION (PSYCHOLOGY); RIBOSOME INACTIVATING PROTEINS, TYPE 1;

EID: 84891671219     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2013.10.055     Document Type: Article

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