-
8
-
-
0026562382
-
Convergent cholinergic activities in aging and Alzheimer's disease
-
(1992)
Neurobiol Aging
, vol.13
, pp. 393-400
-
-
Perry, E.K.1
Johnson, M.2
Kerwin, J.M.3
Piggott, M.A.4
Court, J.A.5
Shaw, P.J.6
Ince, P.G.7
Brown, A.8
Perry, R.H.9
-
14
-
-
0033600274
-
Translating cell biology into therapeutic advances in Alzheimer's disease
-
(1999)
Nature
, vol.399
, Issue.SUPPL.
-
-
Selkoe, D.J.1
-
15
-
-
0033867948
-
Progressive loss of cortical acetylcholinesterase activity in association with cognitive decline in Alzheimer's disease: A positron emission tomography study
-
(2000)
Ann Neurol
, vol.48
, pp. 194-200
-
-
Shinotoh, H.1
Namba, H.2
Fukishi, K.3
Nagatsuka, S.4
Tanaka, N.5
Aotsuka, A.6
Ota, T.7
Tanada, S.8
Irie, T.9
-
17
-
-
0033591017
-
Cholinergic markers in elderly patients with early signs of Alzheimer disease
-
(1999)
J Am Med Assoc
, vol.281
, pp. 1401-1406
-
-
Davis, K.L.1
Mohs, R.2
Marin, D.3
Purohit, D.4
Perl, D.5
Lantz, M.6
Austin, G.7
Haroutunian, V.8
-
18
-
-
0033530073
-
Preservation of nucleus basalis neurons containing choline acetyltransferase and the vesicular acetylcholine transporter in the elderly with mild cognitive impairment and early Alzheimer's disease J Comp Neurol
-
(1999)
, vol.411
, pp. 693-704
-
-
Gilmor, M.L.1
Erickson, J.D.2
Varoqui, H.3
Hersch, L.B.4
Bennett, D.A.5
Cochran, E.J.6
Mufson, E.J.7
Levey, A.I.8
-
19
-
-
0011444914
-
Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 13287-13292
-
-
Sturchler-Pierrat, C.1
Abramowski, D.2
Duke, M.3
Wiederhold, K.H.4
Mistl, C.5
Rothacher, S.6
Ledermann, B.7
Burki, K.8
Frey, P.9
Paganetti, P.A.10
Waridel, C.11
Calhoun, M.E.12
Jucker, M.13
Probst, A.14
Staufenbiel, M.15
Sommer, B.16
-
21
-
-
0001216824
-
Reorganization of cholinergic terminals in the cerebral cortex and hippocampus in transgenic mice carrying mutated presenilin-1 and amyloid precursor protein transgenes
-
(1999)
J Neurosci
, vol.19
, pp. 2706-2716
-
-
Wong, T.P.1
Debeir, T.2
Duff, K.3
Cuello, A.C.4
-
22
-
-
0029742199
-
Correlative memory deficits, Aβ elevation, and amyloid plaques in transgenic mice
-
(1996)
Science
, vol.274
, pp. 99-102
-
-
Hsiao, K.1
Chapman, P.2
Nilsen, S.3
Eckman, C.4
Harigaya, Y.5
Younkin, S.6
Yang, F.7
Cole, G.8
-
25
-
-
0031914718
-
Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes
-
(1998)
Nat Med
, vol.4
, pp. 97-100
-
-
Holcomb, L.1
Gordon, M.N.2
McGowan, E.3
Yu, X.4
Benkovic, S.5
Jantzen, P.6
Wright, K.7
Saad, I.8
Mueller, R.9
Morgan, D.10
Sanders, S.11
Zehr, C.12
O'Campo, K.13
Hardy, J.14
Prada, C.M.15
Eckman, C.16
Younkin, S.17
Hsiao, K.18
Duff, K.19
-
26
-
-
0032417251
-
Transgenic mice expressing Alzheimer amyloid precursor proteins
-
(1998)
Exp Gerontol
, vol.33
, pp. 883-889
-
-
Hsiao, K.1
-
28
-
-
0031981072
-
Amyloid-β deposition in Alzheimer transgenic mice is associated with oxidative stress
-
(1998)
J Neurochem
, vol.70
, pp. 2212-2215
-
-
Smith, M.A.1
Hirai, K.2
Hsiao, K.3
Pappolla, M.A.4
Harris, P.L.5
Siedlack, S.L.6
Tabaton, M.7
Perry, G.8
-
30
-
-
0033360356
-
Impaired synaptic plasticity and learning in aged amyloid precursor protein transgenic mice
-
(1999)
Nat Neurosci
, vol.2
, pp. 271-276
-
-
Chapman, P.F.1
White, G.L.2
Jones, M.W.3
Cooper-Blacketer, D.4
Marshall, V.J.5
Irizarry, M.6
Younkin, L.7
Good, M.A.8
Bliss, T.V.9
Hyman, B.T.10
Younkin, S.G.11
Hsiao, K.K.12
-
33
-
-
0033872024
-
Age-related amyloid beta deposition in transgenic mice overexpressing both Alzheimer mutant presenilin 1 and amyloid beta precursor protein Swedish mutant is not associated with global neuronal loss
-
(2000)
Am J Pathol
, vol.57
, pp. 331-339
-
-
Takeuchi, A.1
Irizarry, M.C.2
Duff, K.3
Saido, T.C.4
Hsiao Ashe, K.5
Hasegawa, M.6
Mann, D.M.7
Hyman, B.T.8
Iwatsubo, T.9
-
35
-
-
0035112955
-
Glutamate receptor dysregulation in the hippocampus of transgenic mice carrying the mutated human amyloid precursor protein
-
(2001)
Neurobiol Dis
, vol.8
, pp. 90-102
-
-
Cha, J.H.1
Farrell, L.A.2
Ahmed, S.F.3
Fray, A.4
Hsiao-Ashe, K.K.5
Young, A.B.6
Penney, J.B.7
Locascio, J.J.8
Hyman, B.T.9
Irizarry, M.C.10
-
36
-
-
0035863055
-
Age-dependent changes in brain, CSF, and plasma amyloid β protein in the Tg2576 transgenic mouse model of Alzheimer's disease
-
(2001)
J Neurosci
, vol.21
, pp. 372-381
-
-
Kawarabashi, T.1
Younkin, L.H.2
Saido, T.C.3
Shoji, M.4
Hsiao Ashe, K.5
Younkin, S.G.6
-
40
-
-
0035108135
-
Alzheimer's disease in man and transgenic mice: Females at higher risk
-
(2001)
Am J Pathol
, vol.158
, pp. 797-801
-
-
Turner, R.S.1
-
44
-
-
0031595258
-
18F]Fluoroethoxy-benzovesamicol, a PET radiotracer for the vesicular acetylcholine transporter and cholinergic synapses
-
(1998)
Synapse
, vol.30
, pp. 263-274
-
-
Mulholland, G.K.1
Wieland, D.M.2
Kilbourn, M.R.3
Frey, K.A.4
Sherman, P.S.5
Carey, J.E.6
Kuhl, D.E.7
-
45
-
-
0029808280
-
In vivo mapping of cholinergic terminals in normal aging, Alzheimer's disease and Parkinson's disease
-
(1996)
Ann Neurol
, vol.40
, pp. 399-410
-
-
Kuhl, D.E.1
Minoshima, S.2
Fessler, J.A.3
Frey, K.A.4
Foster, N.L.5
Ficaro, E.P.6
Wieland, D.M.7
Koeppe, R.A.8
-
46
-
-
10144255848
-
Vesamicol receptor mapping of brain cholinergic neurons with radioiodine-labeled positional isomers of benzovesamicol
-
(1996)
J Med Chem
, vol.39
, pp. 3332-3342
-
-
Jung, Y.W.1
Frey, K.A.2
Mulholland, G.K.3
Del Rosario, R.4
Sherman, P.S.5
Raffel, D.M.6
Van Dort, M.E.7
Kuhl, D.E.8
Gildersleeve, D.L.9
Wieland, D.M.10
-
51
-
-
0016468979
-
A rapid radiochemical method of the determination of choline acetyltransferase
-
(1975)
J Neurochem
, vol.24
, pp. 407-409
-
-
Fonnum, F.1
-
52
-
-
0022186670
-
Measurement of protein using bicinchoninic acid
-
(1985)
Anal Biochem
, vol.150
, pp. 76-85
-
-
Smith, P.K.1
Krohn, R.I.2
Hermanson, G.T.3
Mallia, A.K.4
Gartner, F.H.5
Provenzano, M.D.6
Fujimoto, E.K.7
Goeke, N.M.8
Olson, B.J.9
Klenk, D.C.10
-
54
-
-
0028322017
-
An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants
-
(1994)
Science
, vol.264
, pp. 1336-1340
-
-
Suzuki, N.1
Cheung, T.T.2
Cai, X.D.3
Odaka, A.4
Otvos Jr., L.5
Eckman, C.6
Golde, T.E.7
Younkin, S.G.8
-
56
-
-
0021206313
-
Topochemical localization of choline acetyltransferase and acetyrcholinesterase in mouse brain
-
(1984)
Brain Res
, vol.308
, pp. 364-368
-
-
Gordon, M.N.1
Finch, C.E.2
-
58
-
-
13044287361
-
Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 3228-3233
-
-
Hsia, A.Y.1
Masliah, E.2
McConlogue, L.3
Yu, G.-Q.4
Tatsuno, G.5
Hu, K.6
Kholodenko, D.7
Malenka, R.C.8
Nicoll, R.A.9
Mucke, L.10
-
59
-
-
0034213718
-
1-42 in wild-type human amyloid protein precursor transgenic mice: Synaptotoxicity without plaque formation
-
(2000)
J Neurosci
, vol.20
, pp. 4050-4058
-
-
Mucke, L.1
Masliah, E.2
Yu, G.-Q.3
Mallory, M.4
Rockenstein, E.M.5
Tatsuno, G.6
Hu, K.7
Kholodenko, K.8
McConlogue, L.9
-
62
-
-
0034280437
-
Aging increased amyloid peptide and caused amyloid plaques in brain of old APP/V7171 transgenic mice by a different mechanism than mutant presenilin-1
-
(2000)
J Neurosci
, vol.20
, pp. 6452-6428
-
-
Dewachter, I.1
Van Dorpe, J.2
Smeijers, L.3
Gilis, M.4
Kuiperi, C.5
Laenen, I.6
Caluwaerts, N.7
Moechars, D.8
Checler, F.9
Vanderstichele, H.10
Van Leuven, F.11
-
67
-
-
0033899864
-
Staging of cytoskeletal and β-amyloid changes in human isocortex reveals biphasic synaptic protein response during progression of Alzheimer's disease
-
(2000)
Am J Pathol
, vol.157
, pp. 623-636
-
-
Mukaetova-Ladinska, E.B.1
Garcia-Siera, F.2
Hurt, J.3
Gertz, H.J.4
Xuereb, J.H.5
Hills, R.6
Brayne, C.7
Huppert, F.A.8
Paykel, E.S.9
McGee, M.10
Jakes, R.11
Honer, W.G.12
Harrington, C.R.13
Wischik, C.M.14
-
68
-
-
0033215972
-
Cerebral amyloid induces aberrant axonal sprouting and ectopic terminal formation in amyloid precursor protein transgenic mice
-
(1999)
J Neurosci
, vol.19
, pp. 8552-8559
-
-
Phinney, A.L.1
Deller, T.2
Stalder, M.3
Calhoun, M.E.4
Frotscher, M.5
Sommer, B.6
Staufenbiel, M.7
Jucker, M.8
-
72
-
-
0032459615
-
Hippocampal neurons and synaptophysin-positive bouton number in aging C57BL/6 mice
-
(1998)
Neurobiol Aging
, vol.19
, pp. 599-606
-
-
Calhoun, M.E.1
Kurth, D.2
Phinney, A.L.3
Long, J.M.4
Hengemihle, J.5
Mouton, P.R.6
Ingram, D.K.7
Jucker, M.8
-
74
-
-
0032103915
-
Impairment of basal forebrain cholinergic neurons associated with aging and long-term loss of ovarian function
-
(1998)
Exp Neurol
, vol.151
, pp. 289-302
-
-
Gibbs, R.B.1
-
76
-
-
17944382037
-
Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP
-
(2001)
Science
, vol.293
, pp. 1487-1491
-
-
Lewis, J.1
Dickson, D.W.2
Lin, W.-L.3
Chisholm, L.4
Corral, A.5
Jones, G.6
Yen, S.-H.7
Sahara, N.8
Skipper, L.9
Yager, D.10
Eckman, C.11
Hardy, J.12
Hutton, M.13
McGowan, E.14
|