Injection of IgG 192-saporin into the medial septum produces cholinergic hypofunction and dose-dependent working memory deficits

Brain Research

Volumn 726, Issue 1-2, 1996, Pages 69-79

  Walsh, T J ^a   Herzog, C D ^a   Gandhi, C ^a   Stackman, R W ^a,c   Wiley, R G ^b  

^a RUTGERS UNIVERSITY   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c Lamont Doherty Earth Observatory   (United States)

Author keywords

192 Saponin; Alzheimer's disease; Animal model; Cholinergic basal forebrain; Immunotoxin; Medial septum; Spatial memory

Indexed keywords

DOPAMINE; IMMUNOGLOBULIN G; IMMUNOTOXIN; MONOCLONAL ANTIBODY; NEUROTROPHIN RECEPTOR; SAPORIN; SEROTONIN;

ALZHEIMER DISEASE; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; CHOLINERGIC SYSTEM; CONTROLLED STUDY; DOSE RESPONSE; FOREBRAIN; MALE; MEMORY; NONHUMAN; PRIORITY JOURNAL; RAT; SPATIAL MEMORY; TASK PERFORMANCE;

EID: 0030575306     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-8993(96)00271-5     Document Type: Article

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