-
1
-
-
55849148482
-
The cytokine network in asthma and chronic obstructive pulmonary disease
-
Barnes PJ. The cytokine network in asthma and chronic obstructive pulmonary disease. J Clin Invest 2008;118:3546-56.
-
(2008)
J Clin Invest
, vol.118
, pp. 3546-3556
-
-
Barnes, P.J.1
-
2
-
-
78649532744
-
Resveratrol impairs the release of steroid-resistant inflammatory cytokines from human airway smooth muscle cells in chronic obstructive pulmonary disease
-
Knobloch J, Sibbing B, Jungck D, Lin Y, Urban K, Stoelben E, et al. Resveratrol impairs the release of steroid-resistant inflammatory cytokines from human airway smooth muscle cells in chronic obstructive pulmonary disease. J Pharmacol Exp Ther 2010;335:788-98.
-
(2010)
J Pharmacol Exp Ther
, vol.335
, pp. 788-798
-
-
Knobloch, J.1
Sibbing, B.2
Jungck, D.3
Lin, Y.4
Urban, K.5
Stoelben, E.6
-
3
-
-
79959351840
-
Airway smooth muscle and immunomodulation in acute exacerbations of airway disease
-
Koziol-White CJ, Panettieri RA Jr. Airway smooth muscle and immunomodulation in acute exacerbations of airway disease. Immunol Rev 2011;242:178-85.
-
(2011)
Immunol Rev
, vol.242
, pp. 178-185
-
-
Koziol-White, C.J.1
Panettieri Jr., R.A.2
-
4
-
-
69249202341
-
Transcriptional regulation of cytokine function in airway smooth muscle cells
-
Clarke D, Damera G, Sukkar MB, Tliba O. Transcriptional regulation of cytokine function in airway smooth muscle cells. Pulm Pharmacol Ther 2009;22:436-45.
-
(2009)
Pulm Pharmacol Ther
, vol.22
, pp. 436-445
-
-
Clarke, D.1
Damera, G.2
Sukkar, M.B.3
Tliba, O.4
-
5
-
-
43549103121
-
Differential regulation of CCL-11/eotaxin-1 and CXCL-8/IL-8 by gram-positive and gram-negative bacteria in human airway smooth muscle cells
-
Issa R, Sorrentino R, Sukkar MB, Sriskandan S, Chung KF, Mitchell JA. Differential regulation of CCL-11/eotaxin-1 and CXCL-8/IL-8 by gram-positive and gram-negative bacteria in human airway smooth muscle cells. Respir Res 2008;9:30.
-
(2008)
Respir Res
, vol.9
, pp. 30
-
-
Issa, R.1
Sorrentino, R.2
Sukkar, M.B.3
Sriskandan, S.4
Chung, K.F.5
Mitchell, J.A.6
-
6
-
-
33748056426
-
Toll-like receptor 2, 3, and 4 expression and function in human airway smooth muscle
-
Sukkar MB, Xie S, Khorasani NM, Kon OM, Stanbridge R, Issa R, et al. Toll-like receptor 2, 3, and 4 expression and function in human airway smooth muscle. J Allergy Clin Immunol 2006;118:641-8.
-
(2006)
J Allergy Clin Immunol
, vol.118
, pp. 641-648
-
-
Sukkar, M.B.1
Xie, S.2
Khorasani, N.M.3
Kon, O.M.4
Stanbridge, R.5
Issa, R.6
-
7
-
-
41649115159
-
TLR2 - promiscuous or specific? A critical re-evaluation of a receptor expressing apparent broadspecificity
-
Zähringer U, Lindner B, Inamura S, Heine H, Alexander C. TLR2 - promiscuous or specific? A critical re-evaluation of a receptor expressing apparent broadspecificity. Immunobiology 2008;213:205-24.
-
(2008)
Immunobiology
, vol.213
, pp. 205-224
-
-
Zähringer, U.1
Lindner, B.2
Inamura, S.3
Heine, H.4
Alexander, C.5
-
8
-
-
33646740631
-
Airway selectivity: an update of pharmacokinetic factors affecting local and systemic disposition of inhaled steroids
-
Edsbäcker S, Johansson CJ. Airway selectivity: an update of pharmacokinetic factors affecting local and systemic disposition of inhaled steroids. Basic Clin Pharmacol Toxicol 2006;98:523-36.
-
(2006)
Basic Clin Pharmacol Toxicol
, vol.98
, pp. 523-536
-
-
Edsbäcker, S.1
Johansson, C.J.2
-
9
-
-
65849427529
-
Glucocorticoid resistance in inflammatory diseases
-
Barnes PJ, Adcock IM. Glucocorticoid resistance in inflammatory diseases. Lancet 2009;373:1905-17.
-
(2009)
Lancet
, vol.373
, pp. 1905-1917
-
-
Barnes, P.J.1
Adcock, I.M.2
-
10
-
-
84878538257
-
Short-term vs conventional glucocorticoid therapy in acute exacerbations of chronic obstructive pulmonary disease
-
Leuppi JD, Schuetz P, Bingisser R, Bodmer M, Briel M, Drescher T, et al. Short-term vs conventional glucocorticoid therapy in acute exacerbations of chronic obstructive pulmonary disease. JAMA 2013;309:2223-31.
-
(2013)
JAMA
, vol.309
, pp. 2223-2231
-
-
Leuppi, J.D.1
Schuetz, P.2
Bingisser, R.3
Bodmer, M.4
Briel, M.5
Drescher, T.6
-
11
-
-
33750094661
-
COPD: an inhaled corticosteroid-resistant, oral corticosteroid-responsive condition
-
Saha S, Siva R, Brightling CE, Pavord ID. COPD: an inhaled corticosteroid-resistant, oral corticosteroid-responsive condition. Eur Respir J 2006;27:863-5.
-
(2006)
Eur Respir J
, vol.27
, pp. 863-865
-
-
Saha, S.1
Siva, R.2
Brightling, C.E.3
Pavord, I.D.4
-
12
-
-
70349088498
-
Pneumonia risk in COPD patients receiving inhaled corticosteroids alone or in combination: TORCH study results
-
Crim C, Calverley PM, Anderson JA, Celli B, Ferguson GT, Jenkins C, et al. Pneumonia risk in COPD patients receiving inhaled corticosteroids alone or in combination: TORCH study results. Eur Respir J 2009;34:641-7.
-
(2009)
Eur Respir J
, vol.34
, pp. 641-647
-
-
Crim, C.1
Calverley, P.M.2
Anderson, J.A.3
Celli, B.4
Ferguson, G.T.5
Jenkins, C.6
-
14
-
-
0242441578
-
Inhibition by red wine extract, resveratrol, of cytokine release by alveolar macrophages in COPD
-
Culpitt SV, Rogers DF, Fenwick PS, Shah P, De Matos C, Russell RE, et al. Inhibition by red wine extract, resveratrol, of cytokine release by alveolar macrophages in COPD. Thorax 2003;58:942-6.
-
(2003)
Thorax
, vol.58
, pp. 942-946
-
-
Culpitt, S.V.1
Rogers, D.F.2
Fenwick, P.S.3
Shah, P.4
De Matos, C.5
Russell, R.E.6
-
15
-
-
84872231816
-
Geroprotectors as a novel therapeutic strategy for COPD, an accelerating aging disease
-
Ito K, Colley T, Mercado N. Geroprotectors as a novel therapeutic strategy for COPD, an accelerating aging disease. Int J Chron Obstruct Pulmon Dis 2012;7:641-52.
-
(2012)
Int J Chron Obstruct Pulmon Dis
, vol.7
, pp. 641-652
-
-
Ito, K.1
Colley, T.2
Mercado, N.3
-
16
-
-
79960262017
-
Resveratrol impairs the release of steroid-resistant cytokines from bacterial endotoxin-exposed alveolar macrophages in chronic obstructive pulmonary disease
-
Knobloch J, Hag H, Jungck D, Urban K, Koch A. Resveratrol impairs the release of steroid-resistant cytokines from bacterial endotoxin-exposed alveolar macrophages in chronic obstructive pulmonary disease. Basic Clin Pharmacol Toxicol 2011;109:138-43.
-
(2011)
Basic Clin Pharmacol Toxicol
, vol.109
, pp. 138-143
-
-
Knobloch, J.1
Hag, H.2
Jungck, D.3
Urban, K.4
Koch, A.5
-
18
-
-
1542301591
-
Corticosteroid resistance in chronic obstructive pulmonary disease: inactivation of histone deacetylase
-
Barnes PJ, Ito K, Adcock IM. Corticosteroid resistance in chronic obstructive pulmonary disease: inactivation of histone deacetylase. Lancet 2004;363:731-3.
-
(2004)
Lancet
, vol.363
, pp. 731-733
-
-
Barnes, P.J.1
Ito, K.2
Adcock, I.M.3
-
19
-
-
52649144195
-
Resveratrol and novel potent activators of SIRT1: effects on aging and age-related diseases
-
Knutson MD, Leeuwenburgh C. Resveratrol and novel potent activators of SIRT1: effects on aging and age-related diseases. Nutr Rev 2008;66:591-6.
-
(2008)
Nutr Rev
, vol.66
, pp. 591-596
-
-
Knutson, M.D.1
Leeuwenburgh, C.2
-
20
-
-
31344446119
-
Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF-kappaB suppression
-
Ito K, Yamamura S, Essilfie-Quaye S, Cosio B, Ito M, Barnes PJ, et al. Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF-kappaB suppression. J Exp Med 2006;203:7-13.
-
(2006)
J Exp Med
, vol.203
, pp. 7-13
-
-
Ito, K.1
Yamamura, S.2
Essilfie-Quaye, S.3
Cosio, B.4
Ito, M.5
Barnes, P.J.6
-
21
-
-
72949103252
-
TNFalpha-induced GM-CSF release from human airway smooth muscle cells depends on activation of an ET-1 autoregulatory positive feedback mechanism
-
Knobloch J, Peters H, Jungck D, Müller K, Strauch J, Koch A. TNFalpha-induced GM-CSF release from human airway smooth muscle cells depends on activation of an ET-1 autoregulatory positive feedback mechanism. Thorax 2009;64:1044-52.
-
(2009)
Thorax
, vol.64
, pp. 1044-1052
-
-
Knobloch, J.1
Peters, H.2
Jungck, D.3
Müller, K.4
Strauch, J.5
Koch, A.6
-
22
-
-
84880439899
-
Inflammatory responses of airway smooth muscle cells and effects of endothelin receptor antagonism
-
Knobloch J, Lin Y, Konradi J, Jungck D, Behr J, Strauch J, et al. Inflammatory responses of airway smooth muscle cells and effects of endothelin receptor antagonism. Am J Respir Cell Mol Biol 2013;49:114-27.
-
(2013)
Am J Respir Cell Mol Biol
, vol.49
, pp. 114-127
-
-
Knobloch, J.1
Lin, Y.2
Konradi, J.3
Jungck, D.4
Behr, J.5
Strauch, J.6
-
23
-
-
3042635565
-
Effect of smoking on MAP kinase-induced modulation of IL-8 in human alveolar macrophages
-
Koch A, Giembycz M, Stirling RG, Lim S, Adcock I, Wassermann K, et al. Effect of smoking on MAP kinase-induced modulation of IL-8 in human alveolar macrophages. Eur Respir J 2004;23:805-12.
-
(2004)
Eur Respir J
, vol.23
, pp. 805-812
-
-
Koch, A.1
Giembycz, M.2
Stirling, R.G.3
Lim, S.4
Adcock, I.5
Wassermann, K.6
-
24
-
-
33750627155
-
Alveolar macrophages as orchestrators of COPD
-
Barnes PJ. Alveolar macrophages as orchestrators of COPD. COPD 2004;1:59-70.
-
(2004)
COPD
, vol.1
, pp. 59-70
-
-
Barnes, P.J.1
-
25
-
-
49449094614
-
Oxadiazole-carbonylaminothioureas as SIRT1 and SIRT2 inhibitors
-
Huhtiniemi T, Suuronen T, Rinne VM, Wittekindt C, Lahtela-Kakkonen M, Jarho E, et al. Oxadiazole-carbonylaminothioureas as SIRT1 and SIRT2 inhibitors. J Med Chem 2008;51:4377-80.
-
(2008)
J Med Chem
, vol.51
, pp. 4377-4380
-
-
Huhtiniemi, T.1
Suuronen, T.2
Rinne, V.M.3
Wittekindt, C.4
Lahtela-Kakkonen, M.5
Jarho, E.6
-
26
-
-
33645221885
-
Inhibition of SIRT1 catalytic activity increases p53 acetylation but does not alter cell survival following DNA damage
-
Solomon JM, Pasupuleti R, Xu L, McDonagh T, Curtis R, DiStefano PS, et al. Inhibition of SIRT1 catalytic activity increases p53 acetylation but does not alter cell survival following DNA damage. Mol Cell Biol 2006;26:28-38.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 28-38
-
-
Solomon, J.M.1
Pasupuleti, R.2
Xu, L.3
McDonagh, T.4
Curtis, R.5
DiStefano, P.S.6
-
27
-
-
83455218662
-
Sirtuin 1 (SIRT1): the misunderstood HDAC
-
Stünkel W, Campbell RM. Sirtuin 1 (SIRT1): the misunderstood HDAC. J Biomol Screen 2011;16:1153-69.
-
(2011)
J Biomol Screen
, vol.16
, pp. 1153-1169
-
-
Stünkel, W.1
Campbell, R.M.2
-
28
-
-
42049103914
-
From natural products to small molecule ketone histone deacetylase inhibitors: development of new class specific agents
-
Jones P, Steinkühler C. From natural products to small molecule ketone histone deacetylase inhibitors: development of new class specific agents. Curr Pharm Des 2008;14:545-61.
-
(2008)
Curr Pharm Des
, vol.14
, pp. 545-561
-
-
Jones, P.1
Steinkühler, C.2
-
29
-
-
60949095770
-
Nitric oxide and histone deacetylases: A new relationship between old molecules
-
Watson PM, Riccio A. Nitric oxide and histone deacetylases: A new relationship between old molecules. Commun Integr Biol 2009;2:113.
-
(2009)
Commun Integr Biol
, vol.2
, pp. 113
-
-
Watson, P.M.1
Riccio, A.2
-
30
-
-
78751692077
-
Chronic obstructive pulmonary disease Th1 cells display impaired response to endotoxin
-
Bengoechea JA, Ito K. Chronic obstructive pulmonary disease Th1 cells display impaired response to endotoxin. Am J Respir Crit Care Med 2011;183:148-50.
-
(2011)
Am J Respir Crit Care Med
, vol.183
, pp. 148-150
-
-
Bengoechea, J.A.1
Ito, K.2
-
31
-
-
78751692199
-
The T-helper cell type 1 immune response to gram-negative bacterial infections is impaired in COPD
-
Knobloch J, Schild K, Jungck D, Urban K, Müller K, Schweda EK, et al. The T-helper cell type 1 immune response to gram-negative bacterial infections is impaired in COPD. Am J Respir Crit Care Med 2011;183:204-14.
-
(2011)
Am J Respir Crit Care Med
, vol.183
, pp. 204-214
-
-
Knobloch, J.1
Schild, K.2
Jungck, D.3
Urban, K.4
Müller, K.5
Schweda, E.K.6
-
32
-
-
84861441715
-
Effect of lipoteichoic acid on IL-2 and IL-5 release from T lymphocytes in asthma and COPD
-
Mat Z, Grensemann B, Yakin Y, Knobloch J, Koch A. Effect of lipoteichoic acid on IL-2 and IL-5 release from T lymphocytes in asthma and COPD. Int Immunopharmacol 2012;13:284-91.
-
(2012)
Int Immunopharmacol
, vol.13
, pp. 284-291
-
-
Mat, Z.1
Grensemann, B.2
Yakin, Y.3
Knobloch, J.4
Koch, A.5
-
33
-
-
82455186241
-
Bacteriological differences between COPD exacerbation and community-acquired pneumonia
-
Li XJ, Li Q, Si LY, Yuan QY. Bacteriological differences between COPD exacerbation and community-acquired pneumonia. Respir Care 2011;56:1818-24.
-
(2011)
Respir Care
, vol.56
, pp. 1818-1824
-
-
Li, X.J.1
Li, Q.2
Si, L.Y.3
Yuan, Q.Y.4
-
34
-
-
36148942465
-
Moxifloxacin in the management of exacerbations of chronic bronchitis and COPD
-
Miravitlles M. Moxifloxacin in the management of exacerbations of chronic bronchitis and COPD. Int J Chron Obstruct Pulmon Dis 2007;2:191-204.
-
(2007)
Int J Chron Obstruct Pulmon Dis
, vol.2
, pp. 191-204
-
-
Miravitlles, M.1
-
35
-
-
0038182550
-
Lipoteichoic acid (LTA) of Streptococcus pneumoniae and Staphylococcus aureus activates immune cells via Toll-like receptor (TLR)-2, lipopolysaccharide-binding protein (LBP), and CD14, whereas TLR-4 and MD-2 are not involved
-
Schröder NW, Morath S, Alexander C, Hamann L, Hartung T, Zähringer U, et al. Lipoteichoic acid (LTA) of Streptococcus pneumoniae and Staphylococcus aureus activates immune cells via Toll-like receptor (TLR)-2, lipopolysaccharide-binding protein (LBP), and CD14, whereas TLR-4 and MD-2 are not involved. J Biol Chem 2003;278:15587-94.
-
(2003)
J Biol Chem
, vol.278
, pp. 15587-15594
-
-
Schröder, N.W.1
Morath, S.2
Alexander, C.3
Hamann, L.4
Hartung, T.5
Zähringer, U.6
-
36
-
-
0001701294
-
Toll-like receptor-2 mediates Treponema glycolipid and lipoteichoic acid-induced NF-kappaB translocation
-
Opitz B, Schröder NW, Spreitzer I, Michelsen KS, Kirschning CJ, Hallatschek W, et al. Toll-like receptor-2 mediates Treponema glycolipid and lipoteichoic acid-induced NF-kappaB translocation. J Biol Chem 2001;276:22041-7.
-
(2001)
J Biol Chem
, vol.276
, pp. 22041-22047
-
-
Opitz, B.1
Schröder, N.W.2
Spreitzer, I.3
Michelsen, K.S.4
Kirschning, C.J.5
Hallatschek, W.6
-
37
-
-
0033580949
-
Peptidoglycan- and lipoteichoic acid-induced cell activation is mediated by toll-like receptor 2
-
Schwandner R, Dziarski R, Wesche H, Rothe M, Kirschning CJ. Peptidoglycan- and lipoteichoic acid-induced cell activation is mediated by toll-like receptor 2. J Biol Chem 1999;274:17406-9.
-
(1999)
J Biol Chem
, vol.274
, pp. 17406-17409
-
-
Schwandner, R.1
Dziarski, R.2
Wesche, H.3
Rothe, M.4
Kirschning, C.J.5
-
38
-
-
21044458874
-
Decreased histone deacetylase activity in chronic obstructive pulmonary disease
-
Ito K, Ito M, Elliott WM, Cosio B, Caramori G, Kon OM, et al. Decreased histone deacetylase activity in chronic obstructive pulmonary disease. N Engl J Med 2005;352:1967-76.
-
(2005)
N Engl J Med
, vol.352
, pp. 1967-1976
-
-
Ito, K.1
Ito, M.2
Elliott, W.M.3
Cosio, B.4
Caramori, G.5
Kon, O.M.6
-
39
-
-
63049112375
-
Antioxidant therapeutic advances in COPD
-
Rahman I. Antioxidant therapeutic advances in COPD. Ther Adv Respir Dis 2008;2:351-74.
-
(2008)
Ther Adv Respir Dis
, vol.2
, pp. 351-374
-
-
Rahman, I.1
-
40
-
-
58949096566
-
The potential role of natural agents in treatment of airway inflammation
-
Sharafkhaneh A, Velamuri S, Badmaev V, Lan C, Hanania N. The potential role of natural agents in treatment of airway inflammation. Ther Adv Respir Dis 2007;1:105-20.
-
(2007)
Ther Adv Respir Dis
, vol.1
, pp. 105-120
-
-
Sharafkhaneh, A.1
Velamuri, S.2
Badmaev, V.3
Lan, C.4
Hanania, N.5
-
41
-
-
80052936263
-
Acute exacerbations of chronic obstructive pulmonary disease: identification of biologic clusters and their biomarkers
-
Bafadhel M, McKenna S, Terry S, Mistry V, Reid C, Haldar P, et al. Acute exacerbations of chronic obstructive pulmonary disease: identification of biologic clusters and their biomarkers. Am J Respir Crit Care Med 2011;184:662-71.
-
(2011)
Am J Respir Crit Care Med
, vol.184
, pp. 662-671
-
-
Bafadhel, M.1
McKenna, S.2
Terry, S.3
Mistry, V.4
Reid, C.5
Haldar, P.6
-
42
-
-
33847060910
-
Sirtuin regulates cigarette smoke-induced proinflammatory mediator release via RelA/p65 NF-kappaB in macrophages in vitro and in rat lungs in vivo: implications for chronic inflammation and aging
-
Yang SR, Wright J, Bauter M, Seweryniak K, Kode A, Rahman I. Sirtuin regulates cigarette smoke-induced proinflammatory mediator release via RelA/p65 NF-kappaB in macrophages in vitro and in rat lungs in vivo: implications for chronic inflammation and aging. Am J Physiol Lung Cell Mol Physiol 2007;292:L567-76.
-
(2007)
Am J Physiol Lung Cell Mol Physiol
, vol.292
-
-
Yang, S.R.1
Wright, J.2
Bauter, M.3
Seweryniak, K.4
Kode, A.5
Rahman, I.6
-
43
-
-
80055113353
-
Activation of Sirt1 by resveratrol inhibits TNF-α induced inflammation in fibroblasts
-
Zhu X, Liu Q, Wang M, Liang M, Yang X, Xu X, et al. Activation of Sirt1 by resveratrol inhibits TNF-α induced inflammation in fibroblasts. PLoS ONE 2011;6:e27081.
-
(2011)
PLoS ONE
, vol.6
-
-
Zhu, X.1
Liu, Q.2
Wang, M.3
Liang, M.4
Yang, X.5
Xu, X.6
-
44
-
-
20444444649
-
Mechanism of human SIRT1 activation by resveratrol
-
Borra MT, Smith BC, Denu JM. Mechanism of human SIRT1 activation by resveratrol. J Biol Chem 2005;280:17187-95.
-
(2005)
J Biol Chem
, vol.280
, pp. 17187-17195
-
-
Borra, M.T.1
Smith, B.C.2
Denu, J.M.3
-
45
-
-
33845977734
-
Airway smooth muscle cell as therapeutic target of inflammation
-
Hai CM. Airway smooth muscle cell as therapeutic target of inflammation. Curr Med Chem 2007;14:67-76.
-
(2007)
Curr Med Chem
, vol.14
, pp. 67-76
-
-
Hai, C.M.1
|