-
1
-
-
0003146514
-
Diabetes mellitus
-
Longo DL, Fauci AS, Kasper DL, Hauser SL, Jameson JL, Loscalzo J, eds. New York, NY: McGraw-Hill; Accessed March 6, 2012
-
Powers AC. Diabetes mellitus. In: Longo DL, Fauci AS, Kasper DL, Hauser SL, Jameson JL, Loscalzo J, eds. Harrison's Principles of Internal Medicine. 18th ed. New York, NY: McGraw-Hill; 2012. http://www.accessmedicine.com/content. aspx?aID=9141196. Accessed March 6, 2012.
-
(2012)
Harrison's Principles of Internal Medicine. 18th Ed.
-
-
Powers, A.C.1
-
2
-
-
64649104158
-
Banting lecture: From the triumvirate to the ominous octet: A new paradigm for the treatment of type 2 diabetes mellitus
-
DeFronzo RA. Banting lecture: from the triumvirate to the ominous octet: a new paradigm for the treatment of type 2 diabetes mellitus. Diabetes. 2009;58(4):773-795.
-
(2009)
Diabetes
, vol.58
, Issue.4
, pp. 773-795
-
-
DeFronzo, R.A.1
-
3
-
-
4143151942
-
Pathogenesis of type 2 diabetes mellitus
-
DOI 10.1016/j.mcna.2004.04.013, PII S002571250400063X
-
DeFronzo RA. Pathogenesis of type 2 diabetes mellitus. Med Clin North Am. 2004;88:787-835. (Pubitemid 39090340)
-
(2004)
Medical Clinics of North America
, vol.88
, Issue.4
, pp. 787-835
-
-
DeFronzo, R.A.1
-
4
-
-
0024215846
-
The natural history of impaired glucose tolerance in the Pima Indians
-
Saad MF, Knowler WC, Pettitt DJ, Nelson RG, Mott DM, Bennett PH. The natural history of impaired glucose tolerance in the Pima Indians. N Engl J Med. 1988;319:1500-1505.
-
(1988)
N Engl J Med
, vol.319
, pp. 1500-1505
-
-
Saad, M.F.1
Knowler, W.C.2
Pettitt, D.J.3
Nelson, R.G.4
Mott, D.M.5
Bennett, P.H.6
-
5
-
-
1642377274
-
Impaired Mitochondrial Activity in the Insulin-Resistant Offspring of Patients with Type 2 Diabetes
-
DOI 10.1056/NEJMoa031314
-
Petersen KF, Dufour S, Befroy D, Garcia R, Shulman GI. Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes. N Engl J Med. 2004;350:664-671. (Pubitemid 38364625)
-
(2004)
New England Journal of Medicine
, vol.350
, Issue.7
, pp. 664-671
-
-
Petersen, K.F.1
Dufour, S.2
Befroy, D.3
Garcia, R.4
Shulman, G.I.5
-
6
-
-
84866395319
-
Dysfunctional adiposity and the risk of prediabetes and type 2 diabetes in obese adults
-
Neeland IJ, Turer AT, Ayers CR, et al. Dysfunctional adiposity and the risk of prediabetes and type 2 diabetes in obese adults. JAMA. 2012;308(11):1150-1159.
-
(2012)
JAMA
, vol.308
, Issue.11
, pp. 1150-1159
-
-
Neeland, I.J.1
Turer, A.T.2
Ayers, C.R.3
-
8
-
-
0024507794
-
Fasting hyperglycemia in non-insulin-dependent diabetes mellitus: Contributions of excessive hepatic glucose production and impaired tissue glucose uptake
-
DOI 10.1016/0026-0495(89)90129-7
-
DeFronzo RA, Ferrannini E, Simonson DC. Fasting hyperglycemia in non-insulin dependent diabetes mellitus: contributions of excessive hepatic glucose production and impaired tissue glucose uptake. Metabolism. 1989;38:387-395. (Pubitemid 19105727)
-
(1989)
Metabolism: Clinical and Experimental
, vol.38
, Issue.4
, pp. 387-395
-
-
DeFronzo, R.A.1
Ferrannini, E.2
Simonson, D.C.3
-
9
-
-
0024392514
-
Glucose and free fatty acid metabolism in non-insulin-dependent diabetes mellitus. Evidence for multiple sites of insulin resistance
-
Groop LC, Bonadonna RC, DelPrato S, et al. Glucose and free fatty acid metabolism in non-insulin-dependent diabetes mellitus: evidence for multiple sites of insulin resistance. J Clin Invest. 1989;84(1):205-213. (Pubitemid 19170111)
-
(1989)
Journal of Clinical Investigation
, vol.84
, Issue.1
, pp. 205-213
-
-
Groop, L.C.1
Bonadonna, R.C.2
DelPrato, S.3
Ratheiser, K.4
Zyck, K.5
Ferrannini, E.6
DeFronzo, R.A.7
-
10
-
-
0032980306
-
Familiarity of quantitative metabolic traits in Finnish families with non-insulin dependent diabetes mellitus: Finland-United States Investigation of NIDDM Genes (FUSION) Study Investigators
-
Watanabe RM, Valle T, Hauser ER, et al. Familiarity of quantitative metabolic traits in Finnish families with non-insulin dependent diabetes mellitus: Finland-United States Investigation of NIDDM Genes (FUSION) Study Investigators. Hum Hered. 1999;39:159-168.
-
(1999)
Hum Hered
, vol.39
, pp. 159-168
-
-
Watanabe, R.M.1
Valle, T.2
Hauser, E.R.3
-
11
-
-
77952503211
-
Pathogenesis of insulin resistance in skeletal muscle
-
Abdul-Ghani MA, DeFronzo RA. Pathogenesis of insulin resistance in skeletal muscle. J Biomed Biotechnol. 2010;2010:476279.
-
(2010)
J Biomed Biotechnol
, vol.2010
, pp. 476279
-
-
Abdul-Ghani, M.A.1
DeFronzo, R.A.2
-
12
-
-
0021994683
-
Effects of insulin on peripheral and splanchnic glucose metabolism in noninsulin-dependent (type II) diabetes mellitus
-
DeFronzo RA, Gunnarsson R, Bjorkman O, Olsson M, Wahren J. Effects of insulin on peripheral and splanchnic glucose metabolism in non-insulin-dependent (type II) diabetes mellitus. J Clin Invest. 1985;76:149-155. (Pubitemid 15240430)
-
(1985)
Journal of Clinical Investigation
, vol.76
, Issue.1
, pp. 149-155
-
-
DeFronzo, R.A.1
Gunnarsson, R.2
Bjorkman, O.3
-
13
-
-
64649102357
-
Regulation of intermediatory metabolism during fasting and refeeding
-
DeGroot LJ, Jameson JL, eds. Philadelphia, PA: Elsevier
-
DeFronzo RA, Ferrannini E. Regulation of intermediatory metabolism during fasting and refeeding. In: DeGroot LJ, Jameson JL, eds. Endocrinology. Philadelphia, PA: Elsevier; 2006:1015-1043.
-
(2006)
Endocrinology
, pp. 1015-1043
-
-
DeFronzo, R.A.1
Ferrannini, E.2
-
14
-
-
24944452076
-
Glucose metabolism and regulation: Beyond insulin and glucagon
-
Aronoff SL, Berkowitz K, Shreiner B, et al. Glucose metabolism and regulation: beyond insulin and glucagon. Diabetes Spectrum. 2004;17(3):183-190.
-
(2004)
Diabetes Spectrum
, vol.17
, Issue.3
, pp. 183-190
-
-
Aronoff, S.L.1
Berkowitz, K.2
Shreiner, B.3
-
15
-
-
33845515150
-
The inhibitory effects of insulin on hepatic glucose production are both direct and indirect
-
DOI 10.2337/db06-S009
-
Girard J. The inhibitory effects of insulin on hepatic glucose production are both direct and indirect. Diabetes. 2006;55(suppl 2):S65-S69. (Pubitemid 44927034)
-
(2006)
Diabetes
, vol.55
, Issue.SUPPL. 2
-
-
Girard, J.1
-
16
-
-
80051986265
-
Globalization of diabetes: The role of diet, lifestyle, and genes
-
Hu FB. Globalization of diabetes: the role of diet, lifestyle, and genes. Diabetes Care. 2011;34:1249-1257.
-
(2011)
Diabetes Care
, vol.34
, pp. 1249-1257
-
-
Hu, F.B.1
-
17
-
-
0018192087
-
Insulin binding to monocytes and insulin action in human obesity, starvation, and refeeding
-
DeFronzo RA, Soman V, Sherwin RS, et al. Insulin binding to monocytes and insulin action in human obesity, starvation, and refeeding. J Clin Invest. 1978:204-213. (Pubitemid 8367354)
-
(1978)
Journal of Clinical Investigation
, vol.62
, Issue.1
, pp. 204-213
-
-
DeFronzo, R.A.1
Soman, V.2
Sherwin, R.S.3
-
18
-
-
6944254045
-
Analysis of the relationship between body mass index, insulin resistance, and beta-cell function: A cross-sectional study using the minimal model
-
DOI 10.1016/j.metabol.2004.06.014, PII S0026049504002690
-
Garcia-Estevez DA, Araujo-Vilar D, Saavedra-Gonzalez A, et al. Analysis of the relationship between body mass index, insulin resistance, and beta-cell function: a crosssectional study using the minimal model. Metabolism. 2004;53(11):1462-1466. (Pubitemid 39410387)
-
(2004)
Metabolism: Clinical and Experimental
, vol.53
, Issue.11
, pp. 1462-1466
-
-
Garcia-Estevez, D.A.1
Araujo-Vilar, D.2
Saavedra-Gonzalez, A.3
Fiestras-Janeiro, G.4
Cabezas-Cerrato, J.5
-
20
-
-
61349153606
-
Metabolic flexibility in the development of insulin resistance and type 2 diabetes: Effects of lifestyle
-
Corpeleijn E, Saris WHM, Blaak EE. Metabolic flexibility in the development of insulin resistance and type 2 diabetes: effects of lifestyle. Obes Rev. 2009;10:178-193.
-
(2009)
Obes Rev
, vol.10
, pp. 178-193
-
-
Corpeleijn, E.1
Saris, W.H.M.2
Blaak, E.E.3
-
21
-
-
0036097562
-
Insulin resistance in morbid obesity: Reversal with intramyocellular fat depletion
-
Greco AV, Mingrone G, Giancaterini A, et al. Insulin resistance in morbid obesity: reversal with intramyocellular fat depletion. Diabetes. 2002;51:144-151. (Pubitemid 34517991)
-
(2002)
Diabetes
, vol.51
, Issue.1
, pp. 144-151
-
-
Greco, A.V.1
Mingrone, G.2
Giancaterini, A.3
Manco, M.4
Morroni, M.5
Cinti, S.6
Granzotto, M.7
Vettor, R.8
Camastra, S.9
Ferrannini, E.10
-
22
-
-
0030969532
-
Skeletal muscle triglyceride levels are inversely related to insulin action
-
Pan DA, Lillioja S, Kriketos AD, et al. Skeletal muscle triglyceride levels are inversely related to insulin action. Diabetes. 1997;46(6):983-988. (Pubitemid 27220998)
-
(1997)
Diabetes
, vol.46
, Issue.6
, pp. 983-988
-
-
Pan, D.A.1
Lillioja, S.2
Kriketos, A.D.3
Milner, M.R.4
Baur, L.A.5
Bogardus, C.6
Jenkins, A.B.7
Storlien, L.H.8
-
23
-
-
0032934826
-
1H NMR spectroscopy study
-
DOI 10.1007/s001250051123
-
Krssak M, Petersen KF, Dresner A, et al. Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study. Diabetologia. 1999;42:113-116. (Pubitemid 29039748)
-
(1999)
Diabetologia
, vol.42
, Issue.1
, pp. 113-116
-
-
Krssak, M.1
Falk, P.K.2
Dresner, A.3
DiPietro, L.4
Vogel, S.M.5
Rothman, D.L.6
Shulman, G.I.7
Roden, M.8
-
24
-
-
0029948212
-
Mechanism of free fatty acid-induced insulin resistance in humans
-
Roden M, Price TB, Perseghin G, et al. Mechanism of free fatty acid-induced insulin resistance in humans. J Clin Invest. 1996;97:2859-2865. (Pubitemid 26197099)
-
(1996)
Journal of Clinical Investigation
, vol.97
, Issue.12
, pp. 2859-2865
-
-
Roden, M.1
Price, T.B.2
Perseghin, G.3
Petersen, K.F.4
Rothman, D.L.5
Cline, G.W.6
Shulman, G.I.7
-
25
-
-
0141755328
-
A sustained increase in plasma free fatty acids impairs insulin secretion in nondiabetic subjects genetically predisposed to develop type 2 diabetes
-
DOI 10.2337/diabetes.52.10.2461
-
Kashyap S, Belfort R, Gastaldelli A, et al. A sustained increase in plasma free fatty acids impairs insulin secretion in nondiabetic subjects genetically predisposed to develop type 2 diabetes. Diabetes. 2003;52:2461-2474. (Pubitemid 37210533)
-
(2003)
Diabetes
, vol.52
, Issue.10
, pp. 2461-2474
-
-
Kashyap, S.1
Belfort, R.2
Gastaldelli, A.3
Pratipanawatr, T.4
Berria, R.5
Pratipanawatr, W.6
Bajaj, M.7
Mandarino, L.8
DeFronzo, R.9
Cusi, K.10
-
26
-
-
10344228731
-
Dysfunctional fat cells, lipotoxicity, and type 2 diabetes
-
DeFronzo RA. Dysfunctional fat cells, lipotoxicity, and type 2 diabetes. Int J Clin Pract Suppl. 2004;143:9-21.
-
(2004)
Int J Clin Pract Suppl
, vol.143
, pp. 9-21
-
-
DeFronzo, R.A.1
-
27
-
-
33644695097
-
Effect of a sustained reduction in plasma free fatty acid concentration on intramuscular long-chain fatty acyl-CoAs and insulin action in type 2 diabetic patients
-
DOI 10.2337/diabetes.54.11.3148
-
Bajaj M, Suraamornkul S, Romanelli A, et al. Effect of sustained reduction in plasma free fatty acid concentration on intramuscular long chain-fatty acyl-CoAs and insulin action in patients with type 2 diabetes. Diabetes. 2005;54:3148-3153. (Pubitemid 43334368)
-
(2005)
Diabetes
, vol.54
, Issue.11
, pp. 3148-3153
-
-
Bajaj, M.1
Suraamornkul, S.2
Romanelli, A.3
Cline, G.W.4
Mandarino, L.J.5
Shulman, G.I.6
DeFronzo, R.A.7
-
28
-
-
0031753344
-
Lowering fatty acids potentiates acute insulin response in first degree relatives of people with Type II diabetes
-
DOI 10.1007/s001250051041
-
Paulisso G, Tagliamonte MR, Rizzo MR, et al. Lowering fatty acids potentiates acute insulin response in first degree relatives of people with type II diabetes. Diabetologia. 1998;41:1127-1132. (Pubitemid 28449076)
-
(1998)
Diabetologia
, vol.41
, Issue.10
, pp. 1127-1132
-
-
Paolisso, G.1
Tagliamonte, M.R.2
Rizzo, M.R.3
Gualdiero, P.4
Saccomanno, F.5
Gambardella, A.6
Giugliano, D.7
D'Onofrio, F.8
Howard, B.V.9
-
29
-
-
0032829745
-
Overnight lowering of free fatty acids with acipimox improves insulin resistance and glucose tolerance in obese diabetic and nondiabetic subjects
-
DOI 10.2337/diabetes.48.9.1836
-
Santomauro ATMG, Boden G, Silva MER, et al. Overnight lowering of free fatty acids with acipimox improves insulin resistance and glucose tolerance in obese diabetic and nondiabetic subjects. Diabetes. 1999;48:1836-1841. (Pubitemid 29415205)
-
(1999)
Diabetes
, vol.48
, Issue.9
, pp. 1836-1841
-
-
Santomauro, A.T.M.G.1
Boden, G.2
Silva, M.E.R.3
Rocha, D.M.4
Santos, R.F.5
Ursich, M.J.M.6
Strassmann, P.G.7
Wajchenberg, B.L.8
-
30
-
-
1442352339
-
Role of the Adipocyte, Free Fatty Acids, and Ectopic Fat in Pathogenesis of Type 2 Diabetes Mellitus: Peroxisomal Proliferator-Activated Receptor Agonists Provide a Rational Therapeutic Approach
-
DOI 10.1210/jc.2003-030723
-
Bays H, Mandarino L, DeFronzo RA. Role of the adipocyte, free fatty acids, and ectopic fat in pathogenesis of type 2 diabetes mellitus: peroxisomal proliferator-activated receptor agonists provide a rational therapeutic approach. J Clin Endocrinol Metab. 2004;89(2):463-478. (Pubitemid 38269844)
-
(2004)
Journal of Clinical Endocrinology and Metabolism
, vol.89
, Issue.2
, pp. 463-478
-
-
Bays, H.1
Mandarino, L.2
DeFronzo, R.A.3
-
31
-
-
33845547657
-
Central regulation of energy homeostasis
-
Porte D. Central regulation of energy homeostasis. Diabetes. 2006;55(suppl 2):S155-S160.
-
(2006)
Diabetes
, vol.55
, Issue.SUPPL. 2
-
-
Porte, D.1
-
32
-
-
0032856158
-
Altered hypothalamic function in response to glucose ingestion in obese humans
-
DOI 10.2337/diabetes.48.9.1801
-
Matsuda M, Liu Y, Mahankali S, et al. Altered hypothalamic function in response to glucose ingestion in obese humans. Diabetes. 1999;48:1801-1806. (Pubitemid 29415200)
-
(1999)
Diabetes
, vol.48
, Issue.9
, pp. 1801-1806
-
-
Matsuda, M.1
Liu, Y.2
Mahankali, S.3
Pu, Y.4
Mahankali, A.5
Wang, J.6
DeFronzo, R.A.7
Fox, P.T.8
Gao, J.-H.9
-
33
-
-
84860390432
-
Glucolipotoxicity and beta cells in type 2 diabetes mellitus: Target for durable therapy?
-
van Raalte DH, Diamant M. Glucolipotoxicity and beta cells in type 2 diabetes mellitus: target for durable therapy? Diabetes Res Clin Pract. 2011;93S:S37-S46.
-
(2011)
Diabetes Res Clin Pract
, vol.93 S
-
-
Van Raalte, D.H.1
Diamant, M.2
-
34
-
-
0031963964
-
Defects in insulin secretion and insulin action in non-insulin-dependent diabetes mellitus are inherited. Metabolic studies on offspring of diabetic probands
-
Vauhkonen I, Niskanen L, Vanninen E, Kainulainen S, Uusitupa M, Laakso M. Defects in insulin secretion and insulin action in noninsulin-dependent diabetes mellitus are inherited: metabolic studies on offspring of diabetic probands. J Clin Invest. 1998;101(1):86-96. (Pubitemid 28058907)
-
(1998)
Journal of Clinical Investigation
, vol.101
, Issue.1
, pp. 86-96
-
-
Vauhkonen, I.1
Niskanen, L.2
Vanninen, E.3
Kainulainen, S.4
Uusitupa, M.5
Laakso, M.6
-
35
-
-
0036724133
-
Role of ATP production and uncoupling protein-2 in the insulin secretory defect induced by chronic exposure to high glucose or free fatty acids and effects of peroxisome proliferator-activated receptor-β inhibition
-
Patane G, Anello M, Piro S, Vigneri R, Purrello F, Rabuazzo AM. Role of ATP production and uncoupling protein-2 in the insulin secretory defect induced by chronic exposure to high glucose or free fatty acids and effects of peroxisome proliferator-activated receptor-β inhibition. Diabetes. 2002;51:2749-2756. (Pubitemid 34970928)
-
(2002)
Diabetes
, vol.51
, Issue.9
, pp. 2749-2756
-
-
Patane, G.1
Anello, M.2
Piro, S.3
Vigneri, R.4
Purrello, F.5
Rabuazzo, A.M.6
-
36
-
-
33947144118
-
Thiazolidinediones improve α-cell function in type 2 diabetic patients
-
DOI 10.1152/ajpendo.00551.2006
-
Gastaldelli A, Ferrannini E, Miyazaki Y, et al. Thiazolidinediones improve α-cell function in type 2 diabetic patients. Am J Physiol Endocrinol Metab. 2007;292:E871-E883. (Pubitemid 46411067)
-
(2007)
American Journal of Physiology - Endocrinology and Metabolism
, vol.292
, Issue.3
-
-
Gastaldelli, A.1
Ferrannini, E.2
Miyazaki, Y.3
Matsuda, M.4
Mari, A.5
DeFronzo, R.A.6
-
37
-
-
0023571397
-
Effect of chronic hyperglycemia on in vivo insulin secretion in partially pancreatectomized rats
-
Rossetti L, Shulman GI, Zawalich W, DeFronzo RA. Effect of chronic hyperglycemia on in vivo insulin secretion in partially pancreatectomized rats. J Clin Invest. 1987;80:1037-1044. (Pubitemid 18075639)
-
(1987)
Journal of Clinical Investigation
, vol.80
, Issue.4
, pp. 1037-1044
-
-
Rossetti, L.1
Shulman, G.I.2
Zawalich, W.3
DeFronzo, R.A.4
-
38
-
-
0022522943
-
Chronic hyperglycemia is associated with impaired glucose influence on insulin secretion
-
Leahy JL, Cooper HE, Deal DA, et al. Chronic hyperglycemia is associated with impaired glucose influence on insulin secretion. J Clin Invest. 1986;77:908-915.
-
(1986)
J Clin Invest
, vol.77
, pp. 908-915
-
-
Leahy, J.L.1
Cooper, H.E.2
Deal, D.A.3
-
39
-
-
0022617246
-
Reduced incretin effect in Type 2 (non-insulin-dependent) diabetes
-
DOI 10.1007/BF02427280
-
Nauck M, Stockmann F, Ebert R, Creutzfeldt W. Reduced incretin effect in type 2 (non-insulin-dependent) diabetes. Diabetologia. 1986;29:46-52. (Pubitemid 16162741)
-
(1986)
Diabetologia
, vol.29
, Issue.1
, pp. 46-52
-
-
Nauck, M.1
Stockmann, F.2
Ebert, R.3
Creutzfeldt, W.4
-
40
-
-
58149090676
-
The role of incretins in glucose homeostasis and diabetes treatment
-
Kim W, Egan JM. The role of incretins in glucose homeostasis and diabetes treatment. Pharmacol Rev. 2008;60:470-512.
-
(2008)
Pharmacol Rev
, vol.60
, pp. 470-512
-
-
Kim, W.1
Egan, J.M.2
-
41
-
-
33745227417
-
Incretins and the development of type 2 diabetes
-
Meier JJ, Nauck MA. Incretins and the development of type 2 diabetes. Curren Diab Reports. 2006;6:194-201.
-
(2006)
Curren Diab Reports
, vol.6
, pp. 194-201
-
-
Meier, J.J.1
Nauck, M.A.2
-
42
-
-
3242730474
-
Role of incretin hormones in the regulation of insulin secretion in diabetic and nondiabetic humans
-
DOI 10.1152/ajpendo.00545.2003
-
Holst JJ, Gromada J. Role of incretin hormones in the regulation of insulin secretion in diabetic and nondiabetic humans. Am J Physiol Endocrinol Metab. 2004;287:E199-E206. (Pubitemid 38943883)
-
(2004)
American Journal of Physiology - Endocrinology and Metabolism
, vol.287
, Issue.2
-
-
Holst, J.J.1
Gromada, J.2
-
43
-
-
0001095690
-
Reduced postprandial concentrations of intact biologically active glucagon-like peptide 1 in type 2 diabetic patients
-
Vilsbøll T, Krarup T, Deacon CF, Madsbad S, Holst JJ. Reduced postprandial concentrations of intact biologically active glucagonlike peptide 1 in type 2 diabetic patients. Diabetes. 2001;50(3):609-613. (Pubitemid 32195226)
-
(2001)
Diabetes
, vol.50
, Issue.3
, pp. 609-613
-
-
Vilsboll, T.1
Krarup, T.2
Deacon, C.F.3
Madsbad, S.4
Holst, J.J.5
-
44
-
-
0027391607
-
Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type- 2 diabetes mellitus
-
Nauck MA, Heimesaat MM, Orskov C, Holst JJ, Ebert R, Creutzfeldt W. Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus. J Clin Invest. 1993;91:301-307. (Pubitemid 23037285)
-
(1993)
Journal of Clinical Investigation
, vol.91
, Issue.1
, pp. 301-307
-
-
Nauck, M.A.1
Heimesaat, M.M.2
Orskov, C.3
Holst, J.J.4
Ebert, R.5
Creutzfeldt, W.6
-
45
-
-
58149467276
-
Four weeks of near-normalisation of blood glucose improves the insulin response to glucagonlike peptide-1 and glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes
-
Hojberg PV, Vilsbøll T, Rabol R, et al. Four weeks of near-normalisation of blood glucose improves the insulin response to glucagonlike peptide-1 and glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes. Diabetologia. 2009;52:199-207.
-
(2009)
Diabetologia
, vol.52
, pp. 199-207
-
-
Hojberg, P.V.1
Vilsbøll, T.2
Rabol, R.3
-
46
-
-
0036737543
-
Glucagon dose response curve for hepatic glucose production and glucose disposal in type 2 diabetic patients and normal individuals
-
Matsuda M, DeFronzo RA, Glass L, et al. Glucagon dose response curve for hepatic glucose production and glucose disposal in type 2 diabetic patients and normal individuals. Metabolism. 2002;51:1111-1119.
-
(2002)
Metabolism
, vol.51
, pp. 1111-1119
-
-
Matsuda, M.1
DeFronzo, R.A.2
Glass, L.3
-
47
-
-
0023589251
-
Role of hyperglucagonemia in maintenance of increased rates of hepatic glucose output in type II diabetics
-
Baron AD, Schaeffer L, Shragg P, Kolterman OG. Role of hyperglucagonemia in maintenance of increased rates of hepatic glucose output in type II diabetics. Diabetes. 1987;36:274-283. (Pubitemid 18028415)
-
(1987)
Diabetes
, vol.36
, Issue.3
, pp. 274-283
-
-
Baron, A.D.1
Schaeffer, L.2
Shragg, P.3
Kolterman, O.G.4
-
48
-
-
0035195977
-
Effects of a novel glucagon receptor antagonist (Bay 27-9955) on glucagon-stimulated glucose production in humans
-
DOI 10.1007/s001250100006
-
Petersen KF, Sullivan JT. Effects of a novel glucagon receptor antagonist (Bay 27-9955) on glucagon-stimulated glucose production in humans. Diabetologia. 2001;44:2018-2024. (Pubitemid 33124047)
-
(2001)
Diabetologia
, vol.44
, Issue.11
, pp. 2018-2024
-
-
Petersen, K.F.1
Sullivan, J.T.2
-
49
-
-
64749089393
-
Inhibition of renal glucose reabsorption: A novel strategy for achieving glucose control in type 2 diabetes mellitus
-
Abdul-Ghani MA, DeFronzo RA. Inhibition of renal glucose reabsorption: a novel strategy for achieving glucose control in type 2 diabetes mellitus. Endocr Pract. 2008;14:782-790.
-
(2008)
Endocr Pract
, vol.14
, pp. 782-790
-
-
Abdul-Ghani, M.A.1
DeFronzo, R.A.2
-
50
-
-
83655193529
-
The role of the kidneys in glucose homeostasis: A new path towards normalizing glycaemia
-
DeFronzo RA, Davidson JA, Del Prato S. The role of the kidneys in glucose homeostasis: a new path towards normalizing glycaemia. Diabetes Obes Metab. 2012;14(1):5-14.
-
(2012)
Diabetes Obes Metab
, vol.14
, Issue.1
, pp. 5-14
-
-
DeFronzo, R.A.1
Davidson, J.A.2
Del Prato, S.3
-
51
-
-
78651349221
-
Biology of human sodium glucose transporters
-
Wright EM, Loo DD, Hirayama BA. Biology of human sodium glucose transporters. Physiol Rev. 2011;91:733-794.
-
(2011)
Physiol Rev
, vol.91
, pp. 733-794
-
-
Wright, E.M.1
Loo, D.D.2
Hirayama, B.A.3
-
52
-
-
78651406659
-
SGLT2 mediates glucose reabsorption in the early proximal tubule
-
Vallon V, Platt KA, Cunard R, et al. SGLT2 mediates glucose reabsorption in the early proximal tubule. J Am Soc Nephrol. 2011;22:104-112.
-
(2011)
J Am Soc Nephrol
, vol.22
, pp. 104-112
-
-
Vallon, V.1
Platt, K.A.2
Cunard, R.3
-
53
-
-
33846023326
-
Active sugar transport in health and disease
-
DOI 10.1111/j.1365-2796.2006.01746.x
-
Wright EM, Hirayama BA, Loo DF. Active sugar transport in health and disease. J Intern Med. 2007;261:32-43. (Pubitemid 46046470)
-
(2007)
Journal of Internal Medicine
, vol.261
, Issue.1
, pp. 32-43
-
-
Wright, E.M.1
Hirayama, B.A.2
Loo, D.F.3
-
54
-
-
80052362968
-
Role of sodium-glucose cotransporter 2 (SGLT 2) inhibitors in the treatment of type 2 diabetes
-
Abdul-Ghani MA, Norton L, Defronzo RA. Role of sodium-glucose cotransporter 2 (SGLT 2) inhibitors in the treatment of type 2 diabetes. Endocr Rev. 2011;32:515-531.
-
(2011)
Endocr Rev
, vol.32
, pp. 515-531
-
-
Abdul-Ghani, M.A.1
Norton, L.2
Defronzo, R.A.3
-
55
-
-
33644688031
-
Glucose transporters in human renal proximal tubular cells isolated from the urine of patients with non-insulin-dependent diabetes
-
DOI 10.2337/diabetes.54.12.3427
-
Rahmoune H, Thompson PW, Ward JM, et al. Glucose transporters in human renal proximal tubular cells isolated from the urine of patients with non-insulin-dependent diabetes. Diabetes. 2005;54:3427-3434. (Pubitemid 43334332)
-
(2005)
Diabetes
, vol.54
, Issue.12
, pp. 3427-3434
-
-
Rahmoune, H.1
Thompson, P.W.2
Ward, J.M.3
Smith, C.D.4
Hong, G.5
Brown, J.6
-
56
-
-
84255185190
-
Acute and chronic effects of SGLT2 blockade on glomerular and tubular function in the early diabetic rat
-
Thomson SC, Rieg T, Miracle C, et al. Acute and chronic effects of SGLT2 blockade on glomerular and tubular function in the early diabetic rat. Am J Physiol Regul Integr Comp Physiol. 2012;302:R75-R83.
-
(2012)
Am J Physiol Regul Integr Comp Physiol
, vol.302
-
-
Thomson, S.C.1
Rieg, T.2
Miracle, C.3
|